Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Structure Therapeutics Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 199
- +44 vs. Q3 2025
- Shares held
- 65.8M
- +8.91M (+15.7%) vs. Q3 2025
- Total value
- $4.58B
- +$2.99B (+188.4%) vs. Q3 2025
- New holders
- 72
- 52 more added
- Sold out
- 28
- 63 more reduced
3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Walleye Capital LLC | 2 | $139 | 0.00% | −4,488−100.0% | Reduced |
| Huntington National Bank | 2 | $139 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 5 | $348 | 0.00% | +2+66.7% | Added |
| Cullen/Frost Bankers, Inc. | 8 | $556 | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 9 | $626 | 0.00% | +9 | New |
| Ancora Advisors, LLC | 10 | $695 | 0.00% | +10 | New |
| Capital Analysts, LLC | 18 | $1.00K | 0.00% | 00.0% | Unchanged |
| Bellevue Asset Management, LLC | 15 | $1.04K | 0.00% | +15 | New |
| Bessemer Group Inc | 29 | $2.00K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 41 | $2.85K | 0.00% | −353−89.6% | Reduced |
| Northwestern Mutual Wealth Management Co | 60 | $4.17K | 0.00% | +60 | New |
| SHP Wealth Management | 100 | $6.96K | 0.00% | +100 | New |
| Dynamic Wealth Strategies, LLC | 150 | $10.4K | 0.01% | −400−72.7% | Reduced |
| Daiwa Securities Group Inc. | 186 | $13.0K | 0.00% | −40−17.7% | Reduced |
| Private Wealth Management Group, LLC | 196 | $13.6K | 0.00% | 00.0% | Unchanged |
| North Star Investment Management Corp. | 330 | $23.0K | 0.00% | 00.0% | Unchanged |
| SOA Wealth Advisors, LLC. | 350 | $24.3K | 0.00% | +350 | New |
| Wolff Wiese Magana LLC | 400 | $27.8K | 0.02% | +114+39.9% | Added |
| CWM, LLC | 480 | $33.0K | 0.00% | +125+35.2% | Added |
| Country Trust Bank | 500 | $34.8K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 578 | $40.2K | 0.00% | −493−46.0% | Reduced |
| Farther Finance Advisors, LLC | 690 | $48.0K | 0.00% | +20+3.0% | Added |
| Rockefeller Capital Management L.P. | 731 | $50.8K | 0.00% | −11−1.5% | Reduced |
| GAMMA Investing LLC | 930 | $64.7K | 0.00% | +112+13.7% | Added |
| Jones Financial Companies LLLP | 1,046 | $72.7K | 0.00% | +859+459.4% | Added |
| GF Fund Management Co. Ltd. | 1,312 | $91.3K | 0.00% | +34+2.7% | Added |
| State of Wyoming | 1,761 | $122.5K | 0.01% | +403+29.7% | Added |
| Police & Firemen's Retirement System of New Jersey | 1,829 | $127.2K | 0.00% | +1,829 | New |
| Assetmark, Inc | 2,095 | $145.7K | 0.00% | −289−12.1% | Reduced |
| Persistent Asset Partners Ltd | 2,436 | $169.4K | 0.08% | +2,436 | New |
| Steward Partners Investment Advisory, LLC | 2,540 | $176.7K | 0.00% | −100−3.8% | Reduced |
| Banque Cantonale Vaudoise | 2,945 | $205.0K | 0.01% | +2,945 | New |
| ProShare Advisors LLC | 2,957 | $205.7K | 0.00% | +2,957 | New |
| Invesco Ltd. | 3,200 | $222.6K | 0.00% | −440,537−99.3% | Reduced |
| CIBC World Markets Inc. | 3,248 | $225.9K | 0.00% | +3,248 | New |
| Profund Advisors LLC | 3,507 | $243.9K | 0.01% | +3,507 | New |
| Bank of New York Mellon Corp | 3,604 | $250.6K | 0.00% | +3,604 | New |
| Northern Trust Corp | 3,645 | $253.5K | 0.00% | +3,645 | New |
| Merit Financial Group, LLC | 3,688 | $256.5K | 0.00% | +3,688 | New |
| The PNC Financial Services Group, Inc. | 3,926 | $273.1K | 0.00% | −902−18.7% | Reduced |
| Virtus Investment Advisers, Inc. | 3,967 | $275.9K | 0.07% | −1,154−22.5% | Reduced |
| Gabelli Funds LLC | 4,000 | $278.2K | 0.00% | +4,000 | New |
| E. Ohman J:or Asset Management AB | 4,518 | $314.2K | 0.01% | +4,518 | New |
| Independent Advisor Alliance | 4,543 | $316.0K | 0.01% | +4,543 | New |
| Graham Capital Management, L.P. | 4,778 | $332.3K | 0.01% | +4,778 | New |
| Ikarian Capital, LLC | 4,824 | $335.5K | 0.04% | −158,413−97.0% | Reduced |
| Stifel Financial Corp | 4,830 | $335.9K | 0.00% | +4,830 | New |
| Concurrent Investment Advisors, LLC | 5,000 | $347.8K | 0.00% | +5,000 | New |
| Quadcap Wealth Management, LLC | 7,483 | $354.8K | 0.04% | +7,483 | New |
| Blueshift Asset Management, LLC | 5,213 | $362.6K | 0.10% | +5,213 | New |
| Mirae Asset Global Investments Co., Ltd. | 5,267 | $366.3K | 0.00% | +1,211+29.9% | Added |
| Wells Fargo & Company | 5,664 | $393.9K | 0.00% | −394−6.5% | Reduced |
| Gilbert & Cook, Inc. | 5,682 | $395.2K | 0.05% | +5,682 | New |
| Cetera Investment Advisers | 6,596 | $458.8K | 0.00% | +6,596 | New |
| Signaturefd, LLC | 6,650 | $462.5K | 0.01% | 00.0% | Unchanged |
| PSP Research LLC | 6,719 | $467.3K | 0.41% | +6,719 | New |
| Citigroup Inc | 7,335 | $510.1K | 0.00% | +5,879+403.8% | Added |
| Private Capital Advisors, Inc. | 7,348 | $511.1K | 0.05% | −47,837−86.7% | Reduced |
| Parallel Advisors, LLC | 7,352 | $511.3K | 0.01% | −912−11.0% | Reduced |
| Vestmark Advisory Solutions, Inc. | 7,534 | $524.0K | 0.01% | +7,534 | New |
| MML Investors Services, LLC | 7,825 | $544.2K | 0.00% | +7,825 | New |
| Barclays PLC | 7,833 | $544.8K | 0.00% | +4,060+107.6% | Added |
| PEAK6 LLC | 7,955 | $553.3K | 0.02% | −3,045−27.7% | Reduced |
| LPL Financial LLC | 8,109 | $564.0K | 0.00% | −14,894−64.7% | Reduced |
| Janney Capital Management LLC | 8,513 | $592.0K | 0.04% | −5,205−37.9% | Reduced |
| D. E. Shaw & Co., Inc. | 8,623 | $599.7K | 0.00% | −27,723−76.3% | Reduced |
| Schonfeld Strategic Advisors LLC | 8,727 | $607.0K | 0.00% | +8,727 | New |
| BNP Paribas Arbitrage, SA | 8,746 | $608.3K | 0.00% | −81,685−90.3% | Reduced |
| Susquehanna International Group, LLP | 8,999 | $625.9K | 0.00% | −204,609−95.8% | Reduced |
| SmartHarvest Portfolios, LLC | 9,056 | $629.8K | 0.22% | +9,056 | New |
| HighTower Advisors, LLC | 9,320 | $648.2K | 0.00% | +320+3.6% | Added |
| Mission Wealth Management, LP | 9,583 | $666.5K | 0.01% | 00.0% | Unchanged |
| Bleichroeder LP | 10,000 | $695.5K | 0.12% | −10,000−50.0% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 10,132 | $704.7K | 0.02% | +10,132 | New |
| SG Americas Securities, LLC | 10,147 | $706.0K | 0.00% | −29,553−74.4% | Reduced |
| Royal Bank of Canada | 10,200 | $709.0K | 0.00% | −93−0.9% | Reduced |
| China Universal Asset Management Co., Ltd. | 10,888 | $757.3K | 0.06% | +444+4.3% | Added |
| Envestnet Asset Management Inc | 11,570 | $804.7K | 0.00% | −650−5.3% | Reduced |
| Allianz Asset Management GmbH | 12,000 | $834.6K | 0.00% | +12,000 | New |
| DnB Asset Management AS | 12,639 | $879.0K | 0.00% | −249−1.9% | Reduced |
| Quadrature Capital Ltd | 12,761 | $887.5K | 0.01% | +12,761 | New |
| JPMorgan Chase & Co | 12,956 | $901.1K | 0.00% | −45,192−77.7% | Reduced |
| Brandywine Managers, LLC | 13,357 | $929.0K | 0.46% | +2,300+20.8% | Added |
| J. Goldman & Co LP | 13,601 | $946.0K | 0.04% | +13,601 | New |
| Wexford Capital LP | 14,835 | $1.03M | 0.27% | +14,835 | New |
| SEI Investments Co | 14,903 | $1.04M | 0.00% | +14,903 | New |
| Teachers Retirement System of the State of Kentucky | 17,297 | $1.20M | 0.01% | +6,546+60.9% | Added |
| Acadian Asset Management LLC | 17,606 | $1.22M | 0.00% | +17,606 | New |
| XTX Topco Ltd | 19,193 | $1.33M | 0.04% | +19,193 | New |
| Maven Securities LTD | 20,000 | $1.39M | 0.18% | +20,000 | New |
| Sectoral Asset Management Inc | 23,872 | $1.66M | 1.33% | −198,000−89.2% | Reduced |
| Quinn Opportunity Partners LLC | 25,000 | $1.74M | 0.08% | −17,000−40.5% | Reduced |
| Exchange Traded Concepts, LLC | 25,981 | $1.81M | 0.02% | −32,241−55.4% | Reduced |
| Russell Investments Group, Ltd. | 26,274 | $1.83M | 0.00% | +26,274 | New |
| Nomura Asset Management Co Ltd | 29,152 | $2.03M | 0.01% | +3,296+12.7% | Added |
| DCF Advisers, LLC | 30,000 | $2.09M | 0.69% | −34,250−53.3% | Reduced |
| Bank of America Corp | 31,678 | $2.20M | 0.00% | +17,899+129.9% | Added |
| TrueMark Investments, LLC | 33,893 | $2.36M | 0.45% | −968−2.8% | Reduced |
| Vestal Point Capital, LP | 35,000 | $2.43M | 0.09% | +35,000 | New |
| Tudor Investment Corp Et Al | 35,053 | $2.44M | 0.01% | +35,053 | New |