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Livermore
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Structure Therapeutics Inc.

GPCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001888886

No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Structure Therapeutics Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of GPCR: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders1583199+44
Shares57.0M133.0K65.8M+8.91M (+15.7%)
Value$1.59B$3.72M$4.58B+$2.99B (+188.4%)

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (72)

Institutions that held Structure Therapeutics Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to GPCR in Q4 2025
InstitutionSharesValue% of portfolio
Capitolis Liquid Global Markets LLC878,300$61.1M0.36%
Deutsche Bank AG841,162$58.5M0.02%
Healthcare of Ontario Pension Plan Trust Fund467,800$32.5M0.06%
Farallon Capital Management, L.L.C.454,000$31.6M0.16%
EcoR1 Capital, LLC334,380$23.3M1.07%
Capricorn Fund Managers Ltd252,600$17.6M4.23%
Voloridge Investment Management, LLC250,000$17.4M0.06%
Sio Capital Management, LLC201,500$14.0M2.32%
Marshall Wace, LLP168,584$11.7M0.01%
Jane Street Group, LLC147,217$10.2M0.01%
RTW Investments, LP100,000$6.96M0.07%
Jain Global LLC99,996$6.95M0.07%
SummitTX Capital, L.P.94,671$6.58M0.20%
NEXTBio Capital Management LP94,443$6.57M3.85%
Soleus Capital Management, L.P.90,000$6.26M0.27%
B Group, Inc.90,000$6.26M4.64%
Brevan Howard Capital Management LP86,310$5.96M0.11%
Peregrine Capital Management LLC84,324$5.86M0.18%
Nomura Asset Management International Inc.82,645$5.75M0.01%
Boxer Capital Management, LLC75,000$5.22M1.14%
Burkehill Global Management, LP60,000$4.17M0.27%
Longaeva Partners L.P.60,000$4.17M0.50%
Parkman Healthcare Partners LLC55,000$3.83M0.36%
Integral Health Asset Management, LLC50,000$3.48M0.18%
Seven Grand Managers, LLC50,000$3.48M0.26%
Buckland Partners Management Co LLC50,000$3.48M1.93%
Flax Pond Capital, LLC48,721$3.39M2.52%
Raymond James Financial Inc44,388$3.09M0.00%
ACT Capital Management, LLC38,500$2.68M2.17%
EAM Investors, LLC38,054$2.65M0.29%
Tudor Investment Corp Et Al35,053$2.44M0.01%
Vestal Point Capital, LP35,000$2.43M0.09%
Russell Investments Group, Ltd.26,274$1.83M0.00%
Maven Securities LTD20,000$1.39M0.18%
XTX Topco Ltd19,193$1.33M0.04%
Acadian Asset Management LLC17,606$1.22M0.00%
SEI Investments Co14,903$1.04M0.00%
Wexford Capital LP14,835$1.03M0.27%
J. Goldman & Co LP13,601$946.0K0.04%
Quadrature Capital Ltd12,761$887.5K0.01%
Allianz Asset Management GmbH12,000$834.6K0.00%
Y-Intercept (Hong Kong) Ltd10,132$704.7K0.02%
SmartHarvest Portfolios, LLC9,056$629.8K0.22%
Schonfeld Strategic Advisors LLC8,727$607.0K0.00%
MML Investors Services, LLC7,825$544.2K0.00%
Vestmark Advisory Solutions, Inc.7,534$524.0K0.01%
PSP Research LLC6,719$467.3K0.41%
Cetera Investment Advisers6,596$458.8K0.00%
Gilbert & Cook, Inc.5,682$395.2K0.05%
Blueshift Asset Management, LLC5,213$362.6K0.10%
Quadcap Wealth Management, LLC7,483$354.8K0.04%
Concurrent Investment Advisors, LLC5,000$347.8K0.00%
Stifel Financial Corp4,830$335.9K0.00%
Graham Capital Management, L.P.4,778$332.3K0.01%
Independent Advisor Alliance4,543$316.0K0.01%
E. Ohman J:or Asset Management AB4,518$314.2K0.01%
Gabelli Funds LLC4,000$278.2K0.00%
Merit Financial Group, LLC3,688$256.5K0.00%
Northern Trust Corp3,645$253.5K0.00%
Bank of New York Mellon Corp3,604$250.6K0.00%
Profund Advisors LLC3,507$243.9K0.01%
CIBC World Markets Inc.3,248$225.9K0.00%
ProShare Advisors LLC2,957$205.7K0.00%
Banque Cantonale Vaudoise2,945$205.0K0.01%
Persistent Asset Partners Ltd2,436$169.4K0.08%
Police & Firemen's Retirement System of New Jersey1,829$127.2K0.00%
SOA Wealth Advisors, LLC.350$24.3K0.00%
SHP Wealth Management100$6.96K0.00%
Northwestern Mutual Wealth Management Co60$4.17K0.00%
Bellevue Asset Management, LLC15$1.04K0.00%
Ancora Advisors, LLC10$6950.00%
Allworth Financial LP9$6260.00%

Sold out (28)

Institutions that held Structure Therapeutics Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of GPCR in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Ra Capital Management, L.P.1,517,418$42.5M
Point72 Asset Management, L.P.407,700$11.4M
Paradigm Biocapital Advisors LP372,869$10.4M
Nantahala Capital Management, LLC368,553$10.3M
Schroder Investment Management Group300,947$7.61M
Two Sigma Advisers, LP249,299$6.98M
Readystate Asset Management LP237,188$6.64M
First Light Asset Management, LLC197,350$5.53M
Handelsbanken Fonder AB168,000$4.70M
Octagon Capital Advisors LP115,000$3.22M
Jump Financial, LLC106,400$2.98M
Macquarie Group Ltd58,000$1.62M
Caption Management, LLC56,682$1.59M
Boothbay Fund Management, LLC43,674$1.22M
ADAR1 Capital Management, LLC15,200$425.6K
CCG Wealth Management, LLC10,000$280.0K
Gsa Capital Partners LLP9,886$277.0K
Engineers Gate Manager LP9,593$268.6K
Federated Hermes, Inc.4,500$126.0K
FNY Investment Advisers, LLC1,700$47.0K
Group One Trading, L.P.986$27.6K
Legal & General Group Plc612$17.1K
Harbour Investments, Inc.500$14.0K
HighMark Wealth Management LLC418$11.7K
Advisory Services Network, LLC110$3.08K
Ameritas Advisory Services, LLC100$2.80K
Washington Trust Advisors, Inc.41$1.15K
Global Retirement Partners, LLC10$280

Not filed for Q4 2025 yet (3)

Institutions that held Structure Therapeutics Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding GPCR in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Point72 Europe (London) LLP116,697$3.27M
Cubist Systematic Strategies, LLC16,312$456.7K
Point72 Asia (Singapore) Pte. Ltd.1$28