Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Structure Therapeutics Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 158
- −14 vs. Q2 2025
- Shares held
- 57.0M
- +2.18M (+4.0%) vs. Q2 2025
- Total value
- $1.59B
- +$454.7M (+40.0%) vs. Q2 2025
- New holders
- 22
- 60 more added
- Sold out
- 36
- 48 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| StemPoint Capital LP | 129,335 | $3.62M | 0.73% | +129,335 | New |
| National Bank of Canada | 144,000 | $4.03M | 0.00% | +143,800+71,900.0% | Added |
| Renaissance Technologies LLC | 153,900 | $4.31M | 0.01% | +42,000+37.5% | Added |
| Ikarian Capital, LLC | 163,237 | $4.57M | 1.04% | −19,848−10.8% | Reduced |
| SC China Holding Ltd | 266,062 | $4.61M | 0.24% | 00.0% | Unchanged |
| Eversept Partners, LP | 166,391 | $4.66M | 0.36% | +67,053+67.5% | Added |
| Handelsbanken Fonder AB | 168,000 | $4.70M | 0.01% | −212,000−55.8% | Reduced |
| Jefferies Financial Group Inc. | 170,345 | $4.77M | 0.04% | +170,345 | New |
| Sphera Funds Management Ltd. | 173,931 | $4.87M | 1.16% | +78,000+81.3% | Added |
| Rhenman & Partners Asset Management AB | 180,100 | $5.04M | 0.56% | +45,000+33.3% | Added |
| Two Sigma Investments, LP | 182,911 | $5.12M | 0.01% | +182,911 | New |
| First Light Asset Management, LLC | 197,350 | $5.53M | 0.52% | +75,124+61.5% | Added |
| Pier Capital, LLC | 197,509 | $5.53M | 0.86% | −969−0.5% | Reduced |
| Monashee Investment Management LLC | 200,000 | $5.60M | 2.79% | −230,000−53.5% | Reduced |
| UBS Group AG | 208,092 | $5.83M | 0.00% | +55,111+36.0% | Added |
| Susquehanna International Group, LLP | 213,608 | $5.98M | 0.01% | +137,806+181.8% | Added |
| Sectoral Asset Management Inc | 221,872 | $6.21M | 3.83% | +170,503+331.9% | Added |
| HighVista Strategies LLC | 236,236 | $6.61M | 1.62% | +149,615+172.7% | Added |
| Readystate Asset Management LP | 237,188 | $6.64M | 0.32% | +58,576+32.8% | Added |
| Alyeska Investment Group, L.P. | 244,848 | $6.86M | 0.02% | +244,848 | New |
| Two Sigma Advisers, LP | 249,299 | $6.98M | 0.01% | +213,199+590.6% | Added |
| BlackRock, Inc. | 263,938 | $7.39M | 0.00% | +20,604+8.5% | Added |
| Schroder Investment Management Group | 300,947 | $7.61M | 0.01% | +113,142+60.2% | Added |
| Price T Rowe Associates Inc | 289,393 | $8.10M | 0.00% | −63,475−18.0% | Reduced |
| Bellevue Group AG | 315,857 | $8.84M | 0.18% | −32,670−9.4% | Reduced |
| ArrowMark Colorado Holdings LLC | 323,166 | $9.05M | 0.17% | +24,229+8.1% | Added |
| Nantahala Capital Management, LLC | 368,553 | $10.3M | 0.64% | +200,000+118.7% | Added |
| Paradigm Biocapital Advisors LP | 372,869 | $10.4M | 0.31% | +372,869 | New |
| Deerfield Management Company, L.P. (Series C) | 373,407 | $10.5M | 0.16% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 407,700 | $11.4M | 0.02% | +77,700+23.5% | Added |
| Invesco Ltd. | 443,737 | $12.4M | 0.00% | +19,189+4.5% | Added |
| Citadel Advisors LLC | 443,800 | $12.4M | 0.01% | −884,679−66.6% | Reduced |
| Balyasny Asset Management LLC | 461,553 | $12.9M | 0.03% | +461,553 | New |
| American Century Companies Inc | 486,786 | $13.6M | 0.01% | −4,407−0.9% | Reduced |
| Goldman Sachs Group Inc | 504,396 | $14.1M | 0.00% | +284,222+129.1% | Added |
| Morgan Stanley | 577,741 | $16.2M | 0.00% | −339,605−37.0% | Reduced |
| Standard Life Aberdeen plc | 586,869 | $16.4M | 0.03% | +185,245+46.1% | Added |
| Catalio Capital Management, LP | 651,810 | $18.3M | 3.37% | −18,765−2.8% | Reduced |
| Pacific Heights Asset Management LLC | 700,000 | $19.6M | 0.87% | +240,000+52.2% | Added |
| Franklin Resources Inc | 745,734 | $20.9M | 0.01% | +3,951+0.5% | Added |
| Principal Financial Group Inc | 787,484 | $22.0M | 0.01% | −65,718−7.7% | Reduced |
| Logos Global Management LP | 850,000 | $23.8M | 2.35% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 873,504 | $24.5M | 0.18% | +200,712+29.8% | Added |
| Rock Springs Capital Management LP | 951,154 | $26.6M | 1.56% | −184,725−16.3% | Reduced |
| Siren, L.L.C. | 1,026,811 | $28.8M | 1.12% | +1,026,811 | New |
| TCG Crossover Management, LLC | 1,063,000 | $29.8M | 1.46% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 1,139,300 | $31.9M | 0.77% | −60,000−5.0% | Reduced |
| Ameriprise Financial Inc | 1,224,144 | $34.3M | 0.01% | −364,054−22.9% | Reduced |
| Millennium Management LLC | 1,274,551 | $35.7M | 0.03% | +54,496+4.5% | Added |
| Ra Capital Management, L.P. | 1,517,418 | $42.5M | 0.52% | 00.0% | Unchanged |
| Casdin Capital, LLC | 1,555,000 | $43.5M | 3.63% | +330,000+26.9% | Added |
| Baker Bros. Advisors LP | 1,556,109 | $43.6M | 0.31% | −952,658−38.0% | Reduced |
| BVF Inc | 3,203,917 | $89.7M | 3.64% | +1,432,500+80.9% | Added |
| Deep Track Capital, LP | 4,215,811 | $118.0M | 3.29% | −918,106−17.9% | Reduced |
| Janus Henderson Group PLC | 4,448,826 | $124.6M | 0.06% | −124,180−2.7% | Reduced |
| Avoro Capital Advisors LLC | 5,155,555 | $144.4M | 1.87% | +5,155,555 | New |
| FMR LLC | 5,250,368 | $147.0M | 0.01% | +335,403+6.8% | Added |
| Wellington Management Group LLP | 5,689,187 | $159.3M | 0.03% | −1,186,582−17.3% | Reduced |
| Capital International Investors | 0 | $0 | 0.00% | −1,618,876−100.0% | Sold out |
| Vestal Point Capital, LP | 0 | $0 | 0.00% | −1,200,000−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −321,591−100.0% | Sold out |
| Foresite Capital Management VI LLC | 0 | $0 | 0.00% | −210,000−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −176,060−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −175,636−100.0% | Sold out |
| Canada Pension Plan Investment Board | 0 | $0 | 0.00% | −167,800−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −69,369−100.0% | Sold out |
| Exome Asset Management LLC | 0 | $0 | 0.00% | −53,744−100.0% | Sold out |
| Sofinnova Investments, Inc. | 0 | $0 | 0.00% | −34,353−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −24,600−100.0% | Sold out |
| NEOS Investment Management LLC | 0 | $0 | 0.00% | −22,880−100.0% | Sold out |
| Tema ETFs LLC | 0 | $0 | 0.00% | −22,880−100.0% | Sold out |
| Tejara Capital Ltd | 0 | $0 | 0.00% | −22,400−100.0% | Sold out |
| Paloma Partners Management Co | 0 | $0 | 0.00% | −20,950−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −17,070−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −16,079−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −15,176−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −14,779−100.0% | Sold out |
| Capital Fund Management S.A. | 0 | $0 | 0.00% | −14,350−100.0% | Sold out |
| Maso Capital Partners Ltd | 0 | $0 | 0.00% | −13,000−100.0% | Sold out |
| Griffin Asset Management, Inc. | 0 | $0 | 0.00% | −11,205−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −11,027−100.0% | Sold out |
| Allianz Asset Management GmbH | 0 | $0 | 0.00% | −11,000−100.0% | Sold out |
| Raymond James Financial Inc | 0 | $0 | 0.00% | −6,229−100.0% | Sold out |
| UBS Asset Management Americas Inc | 0 | $0 | 0.00% | −4,170−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −2,888−100.0% | Sold out |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −835−100.0% | Sold out |
| South State Corp. | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| Rhumbline Advisers | 0 | $0 | 0.00% | −450−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −58−100.0% | Sold out |
| CIBC Private Wealth Group, LLC | 0 | $0 | 0.00% | −33−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −32−100.0% | Sold out |
| Federation des caisses Desjardins du Quebec | 0 | $0 | 0.00% | −20−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −13−100.0% | Sold out |
| MAI Capital Management | 0 | $0 | 0.00% | −10−100.0% | Sold out |
| Good Life Advisors, LLC | – | – | – | – | Not filed |