Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Structure Therapeutics Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 158
- −14 vs. Q2 2025
- Shares held
- 57.0M
- +2.18M (+4.0%) vs. Q2 2025
- Total value
- $1.59B
- +$454.7M (+40.0%) vs. Q2 2025
- New holders
- 22
- 60 more added
- Sold out
- 36
- 48 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Point72 Asia (Singapore) Pte. Ltd. | 1 | $28 | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 2 | $56 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 3 | $84 | 0.00% | +3 | New |
| Cullen/Frost Bankers, Inc. | 8 | $224 | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 10 | $280 | 0.00% | 00.0% | Unchanged |
| Bessemer Group Inc | 29 | $1.00K | 0.00% | +29 | New |
| Capital Analysts, LLC | 18 | $1.00K | 0.00% | +18 | New |
| Washington Trust Advisors, Inc. | 41 | $1.15K | 0.00% | 00.0% | Unchanged |
| Ameritas Advisory Services, LLC | 100 | $2.80K | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 110 | $3.08K | 0.00% | +110 | New |
| Jones Financial Companies LLLP | 187 | $4.67K | 0.00% | −580−75.6% | Reduced |
| Private Wealth Management Group, LLC | 196 | $5.49K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 226 | $6.00K | 0.00% | 00.0% | Unchanged |
| Wolff Wiese Magana LLC | 286 | $8.01K | 0.00% | 00.0% | Unchanged |
| North Star Investment Management Corp. | 330 | $9.24K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 355 | $10.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 394 | $11.0K | 0.00% | −504−56.1% | Reduced |
| HighMark Wealth Management LLC | 418 | $11.7K | 0.01% | +418 | New |
| Country Trust Bank | 500 | $14.0K | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 500 | $14.0K | 0.00% | +500 | New |
| Dynamic Wealth Strategies, LLC | 550 | $15.4K | 0.01% | 00.0% | Unchanged |
| Legal & General Group Plc | 612 | $17.1K | 0.00% | +612 | New |
| Farther Finance Advisors, LLC | 670 | $18.8K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 742 | $20.8K | 0.00% | +742 | New |
| GAMMA Investing LLC | 818 | $22.9K | 0.00% | +337+70.1% | Added |
| Group One Trading, L.P. | 986 | $27.6K | 0.00% | −7,079−87.8% | Reduced |
| EverSource Wealth Advisors, LLC | 1,071 | $30.0K | 0.00% | +901+530.0% | Added |
| GF Fund Management Co. Ltd. | 1,278 | $35.8K | 0.00% | −247−16.2% | Reduced |
| State of Wyoming | 1,358 | $38.0K | 0.00% | +28+2.1% | Added |
| Citigroup Inc | 1,456 | $40.8K | 0.00% | −144−9.0% | Reduced |
| FNY Investment Advisers, LLC | 1,700 | $47.0K | 0.02% | 00.0% | Unchanged |
| Assetmark, Inc | 2,384 | $66.8K | 0.00% | −493−17.1% | Reduced |
| Steward Partners Investment Advisory, LLC | 2,640 | $73.9K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 3,773 | $105.6K | 0.00% | −2,555−40.4% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 4,056 | $113.6K | 0.00% | −64−1.6% | Reduced |
| Antipodes Partners Ltd | 4,078 | $114.2K | 0.00% | +1,146+39.1% | Added |
| Walleye Capital LLC | 4,490 | $125.7K | 0.00% | −34,183−88.4% | Reduced |
| Federated Hermes, Inc. | 4,500 | $126.0K | 0.00% | −463,800−99.0% | Reduced |
| The PNC Financial Services Group, Inc. | 4,828 | $135.2K | 0.00% | +413+9.4% | Added |
| Virtus Investment Advisers, Inc. | 5,121 | $143.4K | 0.04% | +889+21.0% | Added |
| Wells Fargo & Company | 6,058 | $169.6K | 0.00% | −1,165−16.1% | Reduced |
| Signaturefd, LLC | 6,650 | $186.2K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 8,264 | $231.4K | 0.00% | 00.0% | Unchanged |
| HighTower Advisors, LLC | 9,000 | $252.0K | 0.00% | +9,000 | New |
| Mission Wealth Management, LP | 9,583 | $268.3K | 0.01% | +9,583 | New |
| Engineers Gate Manager LP | 9,593 | $268.6K | 0.00% | −6,269−39.5% | Reduced |
| Gsa Capital Partners LLP | 9,886 | $277.0K | 0.02% | +9,886 | New |
| CCG Wealth Management, LLC | 10,000 | $280.0K | 0.13% | −140,000−93.3% | Reduced |
| Royal Bank of Canada | 10,293 | $288.0K | 0.00% | +2,711+35.8% | Added |
| China Universal Asset Management Co., Ltd. | 10,444 | $292.4K | 0.02% | −1,523−12.7% | Reduced |
| Teachers Retirement System of the State of Kentucky | 10,751 | $301.0K | 0.00% | −6,900−39.1% | Reduced |
| PEAK6 LLC | 11,000 | $308.0K | 0.01% | +1,555+16.5% | Added |
| Brandywine Managers, LLC | 11,057 | $309.6K | 0.30% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 12,220 | $342.2K | 0.00% | +1,544+14.5% | Added |
| DnB Asset Management AS | 12,888 | $360.9K | 0.00% | +2,253+21.2% | Added |
| Janney Capital Management LLC | 13,718 | $384.0K | 0.02% | +13,718 | New |
| Bank of America Corp | 13,779 | $385.8K | 0.00% | −129−0.9% | Reduced |
| ADAR1 Capital Management, LLC | 15,200 | $425.6K | 0.04% | +200+1.3% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 15,714 | $440.0K | 0.00% | +3,800+31.9% | Added |
| Cubist Systematic Strategies, LLC | 16,312 | $456.7K | 0.01% | −55,378−77.2% | Reduced |
| Voya Investment Management LLC | 16,425 | $459.9K | 0.00% | −14,230−46.4% | Reduced |
| Bleichroeder LP | 20,000 | $560.0K | 0.11% | +10,000+100.0% | Added |
| Trexquant Investment LP | 20,192 | $565.4K | 0.01% | −61,396−75.3% | Reduced |
| LPL Financial LLC | 23,003 | $644.1K | 0.00% | +11,404+98.3% | Added |
| Simplex Trading, LLC | 25,161 | $704.0K | 0.02% | +2,067+9.0% | Added |
| Nomura Asset Management Co Ltd | 25,856 | $724.0K | 0.00% | +982+3.9% | Added |
| Headlands Technologies LLC | 26,814 | $750.8K | 0.06% | +4,476+20.0% | Added |
| Alps Advisors Inc | 27,958 | $782.8K | 0.00% | −3,115−10.0% | Reduced |
| Manufacturers Life Insurance Company, The | 28,532 | $798.9K | 0.00% | −12,257−30.0% | Reduced |
| Alliancebernstein L.P. | 29,559 | $827.7K | 0.00% | +7,060+31.4% | Added |
| TrueMark Investments, LLC | 34,861 | $976.1K | 0.17% | −2,904−7.7% | Reduced |
| TD Asset Management Inc | 36,086 | $1.01M | 0.00% | −7,600−17.4% | Reduced |
| D. E. Shaw & Co., Inc. | 36,346 | $1.02M | 0.00% | +24,181+198.8% | Added |
| Verition Fund Management LLC | 39,349 | $1.10M | 0.01% | −33,635−46.1% | Reduced |
| SG Americas Securities, LLC | 39,700 | $1.11M | 0.00% | +20,461+106.4% | Added |
| Quinn Opportunity Partners LLC | 42,000 | $1.18M | 0.09% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 43,674 | $1.22M | 0.03% | −13,948−24.2% | Reduced |
| Advisor Group Holdings, Inc. | 62,839 | $1.23M | 0.00% | −523−0.8% | Reduced |
| Mariner, LLC | 44,136 | $1.24M | 0.00% | +4,635+11.7% | Added |
| State Street Corp | 46,017 | $1.29M | 0.00% | +12,558+37.5% | Added |
| Private Capital Advisors, Inc. | 55,185 | $1.55M | 0.17% | +55,185 | New |
| Susquehanna Portfolio Strategies, LLC | 55,942 | $1.57M | 0.02% | +15,982+40.0% | Added |
| Caption Management, LLC | 56,682 | $1.59M | 0.09% | +28,508+101.2% | Added |
| Geode Capital Management, LLC | 57,958 | $1.62M | 0.00% | +3,777+7.0% | Added |
| Macquarie Group Ltd | 58,000 | $1.62M | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 58,148 | $1.63M | 0.00% | +15,706+37.0% | Added |
| Exchange Traded Concepts, LLC | 58,222 | $1.63M | 0.02% | −3,510−5.7% | Reduced |
| DAFNA Capital Management LLC | 59,000 | $1.65M | 0.41% | 00.0% | Unchanged |
| Bank of Montreal | 60,722 | $1.70M | 0.00% | +2,649+4.6% | Added |
| Banque Pictet & Cie SA | 64,185 | $1.80M | 0.02% | −6,216−8.8% | Reduced |
| DCF Advisers, LLC | 64,250 | $1.80M | 0.68% | +39,500+159.6% | Added |
| Woodline Partners LP | 65,440 | $1.83M | 0.01% | −111,013−62.9% | Reduced |
| Birchview Capital, LP | 78,000 | $2.18M | 1.65% | +42,000+116.7% | Added |
| BNP Paribas Arbitrage, SA | 90,431 | $2.53M | 0.00% | +24,595+37.4% | Added |
| Susquehanna Fundamental Investments, LLC | 99,617 | $2.79M | 0.11% | −40,100−28.7% | Reduced |
| Jump Financial, LLC | 106,400 | $2.98M | 0.04% | +43,166+68.3% | Added |
| Octagon Capital Advisors LP | 115,000 | $3.22M | 0.50% | +115,000 | New |
| PFM Health Sciences, LP | 115,073 | $3.22M | 0.27% | +58,479+103.3% | Added |
| Point72 Europe (London) LLP | 116,697 | $3.27M | 0.18% | 00.0% | Unchanged |
| Platinum Investment Management Ltd | 122,758 | $3.44M | 0.22% | +47,858+63.9% | Added |