Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Structure Therapeutics Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 151
- −13 vs. Q4 2024
- Shares held
- 56.4M
- −4.53M (−7.4%) vs. Q4 2024
- Total value
- $990.0M
- −$662.8M (−40.1%) vs. Q4 2024
- New holders
- 23
- 47 more added
- Sold out
- 36
- 50 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Susquehanna Fundamental Investments, LLC | 157,961 | $2.73M | 0.05% | +157,961 | New |
| Nantahala Capital Management, LLC | 168,553 | $2.92M | 0.24% | −52,447−23.7% | Reduced |
| Woodline Partners LP | 175,424 | $3.04M | 0.02% | −158,477−47.5% | Reduced |
| Silverarc Capital Management, LLC | 188,069 | $3.26M | 0.68% | +35,674+23.4% | Added |
| Balyasny Asset Management LLC | 202,483 | $3.50M | 0.01% | +202,483 | New |
| Pier Capital, LLC | 212,520 | $3.68M | 0.62% | +79,916+60.3% | Added |
| Candriam Luxembourg S.C.A. | 214,063 | $3.71M | 0.02% | −1,358−0.6% | Reduced |
| Bellevue Group AG | 221,715 | $3.84M | 0.09% | −263,335−54.3% | Reduced |
| Point72 Asset Management, L.P. | 229,431 | $3.97M | 0.01% | −247,267−51.9% | Reduced |
| UBS Group AG | 238,197 | $4.12M | 0.00% | −5,866−2.4% | Reduced |
| ArrowMark Colorado Holdings LLC | 245,186 | $4.24M | 0.07% | +12,277+5.3% | Added |
| Standard Life Aberdeen plc | 248,899 | $4.31M | 0.01% | +77,511+45.2% | Added |
| Ikarian Capital, LLC | 264,085 | $4.57M | 1.49% | −20,000−7.0% | Reduced |
| Monashee Investment Management LLC | 292,862 | $5.07M | 0.60% | +160,862+121.9% | Added |
| Camber Capital Management LP | 300,000 | $5.19M | 0.32% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 324,435 | $5.62M | 0.00% | −258,430−44.3% | Reduced |
| SC China Holding Ltd | 266,062 | $6.20M | 0.36% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 361,565 | $6.26M | 0.07% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 373,407 | $6.46M | 0.13% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 380,000 | $6.58M | 0.03% | +215,000+130.3% | Added |
| Invesco Ltd. | 394,386 | $6.83M | 0.00% | +22,619+6.1% | Added |
| Foresite Capital Management VI LLC | 420,000 | $7.27M | 3.98% | 00.0% | Unchanged |
| Logos Global Management LP | 425,000 | $7.36M | 1.31% | −275,000−39.3% | Reduced |
| Readystate Asset Management LP | 481,241 | $8.33M | 0.42% | +271,899+129.9% | Added |
| American Century Companies Inc | 510,201 | $8.83M | 0.01% | −102,415−16.7% | Reduced |
| Schroder Investment Management Group | 476,136 | $9.41M | 0.01% | +200,825+72.9% | Added |
| BlackRock, Inc. | 566,505 | $9.81M | 0.00% | −44,080−7.2% | Reduced |
| OrbiMed Advisors LLC | 652,028 | $11.3M | 0.27% | 00.0% | Unchanged |
| Morgan Stanley | 692,439 | $12.0M | 0.00% | +305,263+78.8% | Added |
| Casdin Capital, LLC | 700,000 | $12.1M | 0.99% | 00.0% | Unchanged |
| Catalio Capital Management, LP | 704,864 | $12.2M | 3.02% | +135,469+23.8% | Added |
| Franklin Resources Inc | 740,152 | $12.8M | 0.00% | +2,062+0.3% | Added |
| Principal Financial Group Inc | 756,707 | $13.1M | 0.01% | −34,427−4.4% | Reduced |
| Price T Rowe Associates Inc | 777,173 | $13.5M | 0.00% | −617,133−44.3% | Reduced |
| Millennium Management LLC | 790,159 | $13.7M | 0.01% | +39,146+5.2% | Added |
| Citadel Advisors LLC | 992,340 | $17.2M | 0.02% | −486,999−32.9% | Reduced |
| TCG Crossover Management, LLC | 1,063,000 | $18.4M | 2.51% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 1,132,979 | $19.6M | 1.12% | +52,016+4.8% | Added |
| FIL Ltd | 1,150,440 | $19.9M | 0.02% | −149,575−11.5% | Reduced |
| Federated Hermes, Inc. | 1,170,948 | $20.3M | 0.04% | −875,010−42.8% | Reduced |
| Driehaus Capital Management LLC | 1,272,743 | $22.0M | 0.21% | −784,667−38.1% | Reduced |
| Ameriprise Financial Inc | 1,481,809 | $25.7M | 0.01% | +61,757+4.3% | Added |
| Ra Capital Management, L.P. | 1,517,418 | $26.3M | 0.44% | 00.0% | Unchanged |
| Capital International Investors | 1,619,026 | $28.0M | 0.01% | −550.0% | Reduced |
| BVF Inc | 1,771,417 | $30.7M | 1.25% | 00.0% | Unchanged |
| Vestal Point Capital, LP | 1,788,990 | $31.0M | 2.21% | +63,990+3.7% | Added |
| Capital Research Global Investors | 2,164,145 | $37.5M | 0.01% | −1,373,196−38.8% | Reduced |
| Deep Track Capital, LP | 4,100,000 | $71.0M | 2.30% | +1,300,000+46.4% | Added |
| Janus Henderson Group PLC | 4,355,194 | $86.1M | 0.05% | +195,306+4.7% | Added |
| FMR LLC | 5,883,707 | $101.8M | 0.01% | −195,039−3.2% | Reduced |
| Wellington Management Group LLP | 7,791,183 | $134.9M | 0.03% | +5,569+0.1% | Added |
| Boxer Capital Management, LLC | 0 | $0 | 0.00% | −500,000−100.0% | Sold out |
| Ensign Peak Advisors, Inc | 0 | $0 | 0.00% | −308,241−100.0% | Sold out |
| Superstring Capital Management LP | 0 | $0 | 0.00% | −216,811−100.0% | Sold out |
| Alliancebernstein L.P. | 0 | $0 | 0.00% | −142,825−100.0% | Sold out |
| RTW Investments, LP | 0 | $0 | 0.00% | −125,000−100.0% | Sold out |
| Fred Alger Management, LLC | 0 | $0 | 0.00% | −66,662−100.0% | Sold out |
| Russell Investments Group, Ltd. | 0 | $0 | 0.00% | −34,671−100.0% | Sold out |
| Twinbeech Capital LP | 0 | $0 | 0.00% | −28,268−100.0% | Sold out |
| Money Concepts Capital Corp | 0 | $0 | 0.00% | −21,031−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −19,520−100.0% | Sold out |
| M&T Bank Corp | 0 | $0 | 0.00% | −18,110−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −16,880−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −16,873−100.0% | Sold out |
| Natixis Advisors, L.P. | 0 | $0 | 0.00% | −14,459−100.0% | Sold out |
| Griffin Asset Management, Inc. | 0 | $0 | 0.00% | −14,450−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −13,485−100.0% | Sold out |
| EntryPoint Capital, LLC | 0 | $0 | 0.00% | −13,260−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −11,656−100.0% | Sold out |
| LPL Financial LLC | 0 | $0 | 0.00% | −11,485−100.0% | Sold out |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −9,065−100.0% | Sold out |
| Janney Capital Management LLC | 0 | $0 | 0.00% | −9,007−100.0% | Sold out |
| Spire Wealth Management | 0 | $0 | 0.00% | −8,949−100.0% | Sold out |
| Allianz Asset Management GmbH | 0 | $0 | 0.00% | −8,800−100.0% | Sold out |
| Quadcap Wealth Management, LLC | 0 | $0 | 0.00% | −7,851−100.0% | Sold out |
| Envestnet Asset Management Inc | 0 | $0 | 0.00% | −7,403−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −5,445−100.0% | Sold out |
| Vestcor Inc | 0 | $0 | 0.00% | −4,700−100.0% | Sold out |
| Pictet & Cie (Europe) SA | 0 | $0 | 0.00% | −4,143−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −2,242−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −2,000−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −680−100.0% | Sold out |
| Clear Street Markets LLC | 0 | $0 | 0.00% | −246−100.0% | Sold out |
| Vermillion Wealth Management, Inc. | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Fairfield Financial Advisors, LTD | 0 | $0 | 0.00% | −59−100.0% | Sold out |
| Aventura Private Wealth, LLC | 0 | $0 | 0.00% | −28−100.0% | Sold out |
| Capital Analysts, LLC | 0 | $0 | 0.00% | −18−100.0% | Sold out |
| Global Retirement Partners, LLC | – | – | – | – | Not filed |