Structure Therapeutics Inc.
GPCR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001888886
No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Structure Therapeutics Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 165
- +6 vs. Q3 2024
- Shares held
- 60.9M
- −620.5K (−1.0%) vs. Q3 2024
- Total value
- $1.65B
- −$1.04B (−38.7%) vs. Q3 2024
- New holders
- 29
- 66 more added
- Sold out
- 23
- 49 more reduced
2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 191 | $3.62B |
| Q1 2026 | 198 | $3.23B |
| Q4 2025 | 199 | $4.58B |
| Q3 2025 | 158 | $1.59B |
| Q2 2025 | 173 | $1.14B |
| Q1 2025 | 151 | $990.0M |
| Q4 2024 | 165 | $1.65B |
| Q3 2024 | 161 | $2.69B |
| Q2 2024 | 167 | $2.33B |
| Q1 2024 | 119 | $1.86B |
| Q4 2023 | 122 | $1.74B |
| Q3 2023 | 84 | $1.64B |
| Q2 2023 | 48 | $699.4M |
| Q1 2023 | 38 | $346.2M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wexford Capital LP | 81,872 | $2.22M | 0.57% | −16,351−16.6% | Reduced |
| Boothbay Fund Management, LLC | 83,148 | $2.25M | 0.07% | +49,485+147.0% | Added |
| TD Asset Management Inc | 88,882 | $2.41M | 0.00% | −101,874−53.4% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 113,992 | $3.09M | 0.01% | +113,992 | New |
| Barclays PLC | 115,671 | $3.14M | 0.00% | +34,533+42.6% | Added |
| Jane Street Group, LLC | 116,013 | $3.15M | 0.01% | +77,176+198.7% | Added |
| RTW Investments, LP | 125,000 | $3.39M | 0.05% | 00.0% | Unchanged |
| Royal Bank of Canada | 125,692 | $3.41M | 0.00% | +8,147+6.9% | Added |
| Monashee Investment Management LLC | 132,000 | $3.58M | 0.49% | −27,608−17.3% | Reduced |
| Pier Capital, LLC | 132,604 | $3.60M | 0.51% | −1,687−1.3% | Reduced |
| Alliancebernstein L.P. | 142,825 | $3.87M | 0.00% | −16,372−10.3% | Reduced |
| CCG Wealth Management, LLC | 150,000 | $4.07M | 2.27% | +150,000 | New |
| Exome Asset Management LLC | 151,965 | $4.12M | 3.10% | +31,800+26.5% | Added |
| Silverarc Capital Management, LLC | 152,395 | $4.13M | 0.92% | +81,879+116.1% | Added |
| Handelsbanken Fonder AB | 165,000 | $4.47M | 0.02% | +165,000 | New |
| Standard Life Aberdeen plc | 171,388 | $4.65M | 0.01% | −45,695−21.0% | Reduced |
| Readystate Asset Management LP | 209,342 | $5.68M | 0.24% | +125,342+149.2% | Added |
| Candriam Luxembourg S.C.A. | 215,421 | $5.84M | 0.03% | +80,421+59.6% | Added |
| Superstring Capital Management LP | 216,811 | $5.88M | 5.16% | −10,236−4.5% | Reduced |
| Nantahala Capital Management, LLC | 221,000 | $5.99M | 0.42% | +50,000+29.2% | Added |
| ArrowMark Colorado Holdings LLC | 232,909 | $6.32M | 0.08% | −8,183−3.4% | Reduced |
| UBS Group AG | 244,063 | $6.62M | 0.00% | +204,983+524.5% | Added |
| Schroder Investment Management Group | 275,311 | $7.33M | 0.01% | +147,475+115.4% | Added |
| SC China Holding Ltd | 266,062 | $7.54M | 0.32% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 284,085 | $7.70M | 2.20% | +168,885+146.6% | Added |
| Camber Capital Management LP | 300,000 | $8.14M | 0.32% | +300,000 | New |
| Ensign Peak Advisors, Inc | 308,241 | $8.36M | 0.01% | +124,456+67.7% | Added |
| Woodline Partners LP | 333,901 | $9.06M | 0.06% | +2,328+0.7% | Added |
| Baker Bros. Advisors LP | 361,565 | $9.81M | 0.10% | +276,065+322.9% | Added |
| Invesco Ltd. | 371,767 | $10.1M | 0.00% | +14,559+4.1% | Added |
| Deerfield Management Company, L.P. (Series C) | 373,407 | $10.1M | 0.19% | −471,000−55.8% | Reduced |
| Morgan Stanley | 387,176 | $10.5M | 0.00% | +224,690+138.3% | Added |
| First Light Asset Management, LLC | 398,855 | $10.8M | 1.03% | −107,367−21.2% | Reduced |
| Foresite Capital Management VI LLC | 420,000 | $11.4M | 5.08% | +420,000 | New |
| Point72 Asset Management, L.P. | 476,698 | $12.9M | 0.04% | −761,570−61.5% | Reduced |
| Bellevue Group AG | 485,050 | $13.2M | 0.25% | −144,708−23.0% | Reduced |
| Boxer Capital Management, LLC | 500,000 | $13.6M | 1.15% | +500,000 | New |
| Catalio Capital Management, LP | 569,395 | $15.4M | 3.38% | +569,395 | New |
| Goldman Sachs Group Inc | 582,865 | $15.8M | 0.00% | −129,930−18.2% | Reduced |
| Marshall Wace, LLP | 583,207 | $15.8M | 0.02% | +450,531+339.6% | Added |
| BlackRock, Inc. | 610,585 | $16.6M | 0.00% | −69,512−10.2% | Reduced |
| American Century Companies Inc | 612,616 | $16.6M | 0.01% | +67,325+12.3% | Added |
| OrbiMed Advisors LLC | 652,028 | $17.7M | 0.37% | +268,323+69.9% | Added |
| Logos Global Management LP | 700,000 | $19.0M | 2.22% | −550,000−44.0% | Reduced |
| Casdin Capital, LLC | 700,000 | $19.0M | 1.27% | 00.0% | Unchanged |
| Franklin Resources Inc | 738,090 | $20.0M | 0.01% | +31,984+4.5% | Added |
| Millennium Management LLC | 751,013 | $20.4M | 0.02% | −160,438−17.6% | Reduced |
| Principal Financial Group Inc | 791,134 | $21.5M | 0.01% | +245,775+45.1% | Added |
| TCG Crossover Management, LLC | 1,063,000 | $28.8M | 2.82% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 1,080,963 | $29.3M | 1.12% | +17,053+1.6% | Added |
| FIL Ltd | 1,300,015 | $35.3M | 0.03% | −10,520−0.8% | Reduced |
| Price T Rowe Associates Inc | 1,394,306 | $37.8M | 0.00% | −690,381−33.1% | Reduced |
| Ameriprise Financial Inc | 1,420,052 | $38.5M | 0.01% | +322,601+29.4% | Added |
| Citadel Advisors LLC | 1,479,339 | $40.1M | 0.04% | +27,841+1.9% | Added |
| Ra Capital Management, L.P. | 1,517,418 | $41.2M | 0.55% | −379,354−20.0% | Reduced |
| Capital International Investors | 1,619,081 | $43.9M | 0.01% | +103,059+6.8% | Added |
| Vestal Point Capital, LP | 1,725,000 | $46.8M | 2.77% | +575,000+50.0% | Added |
| BVF Inc | 1,771,417 | $48.0M | 1.63% | −467,569−20.9% | Reduced |
| Federated Hermes, Inc. | 2,045,958 | $55.5M | 0.12% | −365,642−15.2% | Reduced |
| Driehaus Capital Management LLC | 2,057,410 | $55.8M | 0.46% | −469,020−18.6% | Reduced |
| Deep Track Capital, LP | 2,800,000 | $75.9M | 2.85% | +1,579,492+129.4% | Added |
| Capital Research Global Investors | 3,537,341 | $95.9M | 0.02% | +6,891+0.2% | Added |
| Janus Henderson Group PLC | 4,159,888 | $112.8M | 0.06% | +203,010+5.1% | Added |
| FMR LLC | 6,078,746 | $164.9M | 0.01% | −49,698−0.8% | Reduced |
| Wellington Management Group LLP | 7,785,614 | $211.1M | 0.04% | +15,843+0.2% | Added |
| Octagon Capital Advisors LP | 0 | $0 | 0.00% | −1,198,000−100.0% | Sold out |
| T. Rowe Price Investment Management, Inc. | 0 | $0 | 0.00% | −715,968−100.0% | Sold out |
| Avidity Partners Management LP | 0 | $0 | 0.00% | −430,900−100.0% | Sold out |
| Boxer Capital, LLC | 0 | $0 | 0.00% | −400,000−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −250,000−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −144,500−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −71,615−100.0% | Sold out |
| Altium Capital Management LP | 0 | $0 | 0.00% | −70,000−100.0% | Sold out |
| Blue Owl Capital Holdings LP | 0 | $0 | 0.00% | −65,000−100.0% | Sold out |
| Plustick Management LLC | 0 | $0 | 0.00% | −45,000−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −40,706−100.0% | Sold out |
| Perceptive Advisors LLC | 0 | $0 | 0.00% | −34,852−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −30,464−100.0% | Sold out |
| AlphaCentric Advisors LLC | 0 | $0 | 0.00% | −26,000−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −16,703−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −11,938−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −7,660−100.0% | Sold out |
| Shay Capital LLC | 0 | $0 | 0.00% | −7,500−100.0% | Sold out |
| Gilbert & Cook, Inc. | 0 | $0 | 0.00% | −5,682−100.0% | Sold out |
| Crestline Management, LP | 0 | $0 | 0.00% | −5,310−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −5,163−100.0% | Sold out |
| Dearborn Partners LLC | 0 | $0 | 0.00% | −4,600−100.0% | Sold out |
| Truvestments Capital LLC | 0 | $0 | 0.00% | −82−100.0% | Sold out |
| PEAK6 Investments LLC | – | – | – | – | Not filed |
| Planning Capital Management Corp | – | – | – | – | Not filed |