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Apellis Pharmaceuticals, Inc.

APLSDelisted
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted in 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

APLS is no longer listed, so this page shows Q1 2026. 13F filings for later quarters list far fewer holders.

Institutional holders
324
+49 vs. Q4 2025
Shares held
140.4M
+25.8M (+22.6%) vs. Q4 2025
Total value
$5.56B
+$2.69B (+93.5%) vs. Q4 2025
New holders
127
91 more added
Sold out
78
72 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 324 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ1 2026: $5.56B
Q1 2021: $2.80BQ2 2021: $4.13BQ3 2021: $2.29BQ4 2021: $3.91BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.67BQ4 2022: $5.26BQ1 2023: $7.49BQ2 2023: $9.81BQ3 2023: $4.34BQ4 2023: $7.16BQ1 2024: $6.97BQ2 2024: $4.56BQ3 2024: $3.52BQ4 2024: $4.05BQ1 2025: $2.80BQ2 2025: $2.29BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.29B
Q1 2025255$2.80B
Q4 2024260$4.05B
Q3 2024265$3.52B
Q2 2024263$4.56B
Q1 2024302$6.97B
Q4 2023284$7.16B
Q3 2023256$4.34B
Q2 2023317$9.81B
Q1 2023282$7.49B
Q4 2022244$5.26B
Q3 2022250$6.67B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.91B
Q3 2021181$2.29B
Q2 2021205$4.13B
Q1 2021175$2.80B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2025.

Institutions holding APLS in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Asset Management, Ltd71,855$2.89M0.00%+71,855New
ADAR1 Capital Management, LLC72,500$2.92M0.18%+52,500+262.5%Added
Acadian Asset Management LLC74,716$3.00M0.00%−131,270−63.7%Reduced
HGC Investment Management Inc.75,000$3.02M0.67%+75,000New
Gotham Asset Management, LLC78,750$3.17M0.01%−89,705−53.3%Reduced
State of Wisconsin Investment Board79,680$3.21M0.01%+12,764+19.1%Added
Great West Life Assurance Co80,662$3.25M0.01%+72,167+849.5%Added
Perceptive Advisors LLC80,956$3.26M0.06%+80,956New
Profund Advisors LLC81,190$3.27M0.12%+19,358+31.3%Added
Abc Arbitrage SA83,317$3.35M0.45%+83,317New
New York State Common Retirement Fund84,451$3.40M0.00%−19,567−18.8%Reduced
CI Private Wealth, LLC84,571$3.40M0.00%+84,571New
Exome Asset Management LLC85,517$3.44M2.02%−50,332−37.0%Reduced
Los Angeles Capital Management LLC85,913$3.46M0.01%−865,803−91.0%Reduced
Caitong International Asset Management Co., Ltd90,466$3.64M0.67%+90,466New
Prudential Financial Inc92,510$3.72M0.00%+92,510New
California State Teachers Retirement System94,833$3.82M0.00%+21,630+29.5%Added
Deutsche Bank AG95,365$3.84M0.00%−1,289,898−93.1%Reduced
State Board of Administration of Florida Retirement System96,125$3.87M0.01%00.0%Unchanged
Nine Masts Capital Ltd97,478$3.92M0.61%+97,478New
Barclays PLC98,327$3.96M0.00%−89,385−47.6%Reduced
Alps Advisors Inc104,058$4.19M0.02%+362+0.3%Added
Sagefield Capital LP104,065$4.19M0.30%+104,065New
Price T Rowe Associates Inc106,908$4.30M0.00%+11,873+12.5%Added
Prelude Capital Management, LLC111,468$4.48M0.34%+72,947+189.4%Added
Water Island Capital LLC120,500$4.85M0.65%+120,500New
Quantinno Capital Management LP121,270$4.88M0.01%+89,507+281.8%Added
Schonfeld Strategic Advisors LLC123,824$4.98M0.04%+123,824New
Royal Bank of Canada126,701$5.10M0.00%+38,014+42.9%Added
Twin Securities, Inc.127,440$5.13M2.53%+127,440New
Slotnik Capital, LLC135,000$5.43M1.61%+135,000New
Chicago Capital Management, LLC190,000$5.76M4.77%+190,000New
CNH Partners LLC146,604$5.90M0.10%+146,604New
Empowered Funds, LLC148,038$5.96M0.04%+134,657+1,006.3%Added
Swiss National Bank149,500$6.01M0.00%00.0%Unchanged
Picton Mahoney Asset Management150,000$6.03M0.06%+150,000New
Mackenzie Financial Corp153,330$6.17M0.01%+57,119+59.4%Added
Rock Springs Capital Management LP162,750$6.55M0.39%+12,250+8.1%Added
Gardner Lewis Asset Management L P165,000$6.64M1.44%+165,000New
UBS Asset Management Americas Inc179,953$7.24M0.00%+1,065+0.6%Added
Fiduciary Trust Co180,161$7.25M0.09%−93−0.1%Reduced
Rafferty Asset Management, LLC180,471$7.26M0.03%+9,015+5.3%Added
Boothbay Fund Management, LLC183,522$7.38M0.17%+162,107+757.0%Added
Ameriprise Financial Inc183,578$7.39M0.00%−406,019−68.9%Reduced
D. E. Shaw & Co., Inc.186,853$7.52M0.01%−262,823−58.4%Reduced
Pictet Asset Management Holding SA426,821$7.56M0.01%+35,937+9.2%Added
Gabelli & Co Investment Advisers, Inc.200,600$8.07M1.20%+200,600New
Trexquant Investment LP205,219$8.26M0.06%+10,627+5.5%Added
Sphera Funds Management Ltd.214,914$8.65M1.49%−36,047−14.4%Reduced
Bank of Montreal215,041$8.65M0.00%+38,470+21.8%Added
Jefferies Financial Group Inc.219,000$8.81M0.11%+210,282+2,412.0%Added
Nuveen, LLC220,114$8.86M0.00%−461,705−67.7%Reduced
Westchester Capital Management, LLC227,489$9.15M0.44%+227,489New
Legal & General Group Plc228,255$9.18M0.00%+142,766+167.0%Added
Granite Investment Partners, LLC231,917$9.33M0.57%−95,177−29.1%Reduced
Wellington Management Group LLP249,635$10.0M0.00%−12,471,717−98.0%Reduced
683 Capital Management, LLC250,000$10.1M0.93%−80,000−24.2%Reduced
Capstone Investment Advisors, LLC250,000$10.1M0.08%+250,000New
Janus Henderson Group PLC252,130$10.1M0.00%+21,810+9.5%Added
Rhumbline Advisers275,540$11.1M0.01%+158,623+135.7%Added
Jump Financial, LLC291,488$11.7M0.17%+97,612+50.3%Added
O'Connor Alternative Investments LLC300,000$12.1M0.63%+300,000New
Meteora Capital, LLC300,000$12.1M0.89%+300,000New
Beck Bode, LLC312,841$12.6M2.13%+312,841New
Gabelli Funds LLC321,200$12.9M0.09%+321,200New
Susquehanna International Group, LLP340,086$13.7M0.02%−193,823−36.3%Reduced
Vivaldi Asset Management, LLC350,800$14.1M0.74%+350,800New
Public Sector Pension Investment Board366,674$14.8M0.05%+366,674New
Alliancebernstein L.P.638,291$16.0M0.01%+603,761+1,748.5%Added
Verition Fund Management LLC400,000$16.1M0.16%+400,000New
LMR Partners LLP403,622$16.2M0.15%+403,622New
AQR Capital Management LLC427,970$17.2M0.01%−1,848,717−81.2%Reduced
Invesco Ltd.437,868$17.6M0.00%+211,892+93.8%Added
Squarepoint Ops LLC449,796$18.1M0.04%+257,640+134.1%Added
Absolute Gestao de Investimentos Ltda.450,000$18.1M2.07%+450,000New
Principal Financial Group Inc499,053$20.1M0.01%+499,053New
Two Sigma Investments, LP521,965$21.0M0.02%−40,396−7.2%Reduced
Bank of New York Mellon Corp524,789$21.1M0.00%+252,864+93.0%Added
Ossiam555,953$22.4M0.39%+124,174+28.8%Added
BNP Paribas Arbitrage, SA584,192$23.5M0.02%+26,601+4.8%Added
Tudor Investment Corp Et Al650,000$26.1M0.14%+435,000+202.3%Added
Vanguard Fiduciary Trust Co654,922$26.3M0.01%+654,922New
Citigroup Inc657,223$26.4M0.02%+35,065+5.6%Added
Charles Schwab Investment Management Inc675,864$27.2M0.00%+31,419+4.9%Added
Weiss Asset Management LP700,000$28.2M0.52%+700,000New
Northern Trust Corp738,440$29.7M0.00%+41,919+6.0%Added
Kynam Capital Management, LP825,000$33.2M2.11%−83,607−9.2%Reduced
Oddo BHF Asset Management SAS825,000$33.2M1.31%+825,000New
Alpine Associates Management Inc.864,000$34.8M2.05%+864,000New
Magnetar Financial LLC869,229$35.0M0.36%+869,229New
JPMorgan Chase & Co2,047,927$35.0M0.00%+1,890,173+1,198.2%Added
First Trust Advisors LP903,637$36.4M0.03%+407,690+82.2%Added
Man Group plc915,689$36.8M0.08%+771,418+534.7%Added
Marshall Wace, LLP929,019$37.4M0.04%−61,829−6.2%Reduced
Renaissance Technologies LLC935,958$37.7M0.06%+302,900+47.8%Added
Woodline Partners LP976,175$39.3M0.15%+433,194+79.8%Added
Capitolis Liquid Global Markets LLC1,013,500$40.8M0.26%+1,013,500New
Soros Fund Management LLCSuperinvestorSoros Fund Management1,056,000$42.5M0.58%+1,056,000New
Kryger Capital LLC1,100,000$44.3M3.13%+1,100,000New
FIL Ltd1,140,000$45.9M0.04%+1,140,000New