Apellis Pharmaceuticals, Inc.
APLSDelisted May 14, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 280
- +14 vs. Q3 2025
- Shares held
- 126.4M
- +4.65M (+3.8%) vs. Q3 2025
- Total value
- $3.17B
- +$415.1M (+15.0%) vs. Q3 2025
- New holders
- 61
- 89 more added
- Sold out
- 47
- 102 more reduced
7 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.28B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.04B |
| Q3 2024 | 265 | $3.41B |
| Q2 2024 | 263 | $4.43B |
| Q1 2024 | 302 | $6.65B |
| Q4 2023 | 284 | $6.82B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.71B |
| Q1 2023 | 282 | $7.28B |
| Q4 2022 | 244 | $5.20B |
| Q3 2022 | 250 | $6.66B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.83B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.08B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Swiss Life Asset Management Ltd | 10,832 | $272.1K | 0.00% | +10,832 | New |
| Teacher Retirement System of Texas | 11,225 | $282.0K | 0.00% | −7,287−39.4% | Reduced |
| Franklin Resources Inc | 11,304 | $284.0K | 0.00% | +11,304 | New |
| Bridgefront Capital, LLC | 11,326 | $284.5K | 0.07% | +11,326 | New |
| Quest Partners LLC | 11,741 | $294.9K | 0.02% | −11,358−49.2% | Reduced |
| Wedmont Private Capital | 11,883 | $314.8K | 0.01% | +468+4.1% | Added |
| Freestone Grove Partners LP | 12,537 | $314.9K | 0.00% | +12,537 | New |
| Walleye Trading LLC | 12,699 | $319.0K | 0.01% | +2,258+21.6% | Added |
| Twinbeech Capital LP | 13,152 | $330.4K | 0.02% | +4,225+47.3% | Added |
| Empowered Funds, LLC | 13,381 | $336.1K | 0.01% | +40+0.3% | Added |
| Summit Trail Advisors, LLC | 13,851 | $347.9K | 0.01% | +3,575+34.8% | Added |
| Pallas Capital Advisors LLC | 13,885 | $348.8K | 0.01% | −19,192−58.0% | Reduced |
| Birchview Capital, LP | 14,000 | $351.7K | 0.21% | 00.0% | Unchanged |
| Nomura Holdings Inc | 14,200 | $356.7K | 0.00% | −22,400−61.2% | Reduced |
| M&T Bank Corp | 14,477 | $363.8K | 0.00% | +1,452+11.1% | Added |
| GWM Advisors LLC | 14,570 | $366.0K | 0.00% | +14,570 | New |
| Maven Securities LTD | 15,000 | $376.8K | 0.05% | +15,000 | New |
| Victory Capital Management Inc | 15,197 | $381.7K | 0.00% | −75−0.5% | Reduced |
| Vident Advisory, LLC | 15,553 | $390.7K | 0.00% | −19,828−56.0% | Reduced |
| Duncan Williams Asset Management, LLC | 17,005 | $393.7K | 0.10% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 16,117 | $404.9K | 0.01% | −74,904−82.3% | Reduced |
| KLP Kapitalforvaltning AS | 16,200 | $406.9K | 0.00% | +600+3.8% | Added |
| Creative Planning | 16,439 | $412.9K | 0.00% | −19,206−53.9% | Reduced |
| Jain Global LLC | 16,877 | $423.9K | 0.00% | +16,877 | New |
| Allianz Asset Management GmbH | 17,000 | $427.0K | 0.00% | 00.0% | Unchanged |
| Mercer Global Advisors Inc | 17,668 | $443.8K | 0.00% | −21,375−54.7% | Reduced |
| Advent Capital Management | 18,000 | $452.2K | 0.01% | +18,000 | New |
| Xponance, Inc. | 18,164 | $456.3K | 0.00% | +681+3.9% | Added |
| Qube Research & Technologies Ltd | 18,843 | $473.3K | 0.00% | −101,160−84.3% | Reduced |
| Diversified Trust Co | 18,942 | $475.8K | 0.01% | +18,942 | New |
| Odyssean, LLC | 19,207 | $482.5K | 0.35% | +19,207 | New |
| ADAR1 Capital Management, LLC | 20,000 | $502.4K | 0.04% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 20,617 | $517.9K | 0.04% | −1,520−6.9% | Reduced |
| Arizona State Retirement System | 21,010 | $527.8K | 0.00% | −1,288−5.8% | Reduced |
| IMC-Chicago, LLC | 21,324 | $535.7K | 0.01% | +21,324 | New |
| Boothbay Fund Management, LLC | 21,415 | $537.9K | 0.01% | −157,811−88.1% | Reduced |
| PSP Research LLC | 21,866 | $549.3K | 0.48% | +21,866 | New |
| Manufacturers Life Insurance Company, The | 22,852 | $574.0K | 0.00% | +143+0.6% | Added |
| Marex Group plc | 23,000 | $577.8K | 0.01% | +23,000 | New |
| Entropy Technologies, LP | 23,128 | $581.0K | 0.03% | −1,475−6.0% | Reduced |
| Cerity Partners LLC | 23,971 | $602.2K | 0.00% | −104,139−81.3% | Reduced |
| Quadrature Capital Ltd | 24,075 | $604.8K | 0.01% | +24,075 | New |
| Virginia Retirement Systems Et Al | 24,365 | $612.0K | 0.00% | −1,100−4.3% | Reduced |
| Erste Asset Management GmbH | 25,300 | $636.8K | 0.01% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 25,364 | $637.1K | 0.00% | +4,047+19.0% | Added |
| Ieq Capital, LLC | 25,500 | $640.6K | 0.00% | −271,284−91.4% | Reduced |
| State of New Jersey Common Pension Fund D | 25,863 | $649.7K | 0.00% | +25,863 | New |
| Virtus Investment Advisers, Inc. | 27,086 | $680.4K | 0.18% | +4,013+17.4% | Added |
| Simplex Trading, LLC | 27,187 | $682.9K | 0.02% | −26,714−49.6% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 30,175 | $722.4K | 0.00% | −47,333−61.1% | Reduced |
| Amundi | 30,721 | $771.7K | 0.00% | −1,462,957−97.9% | Reduced |
| Dark Forest Capital Management LP | 31,091 | $781.0K | 0.04% | +31,091 | New |
| Y-Intercept (Hong Kong) Ltd | 31,581 | $793.3K | 0.02% | −132,232−80.7% | Reduced |
| Quantinno Capital Management LP | 31,763 | $797.9K | 0.00% | −16,656−34.4% | Reduced |
| FMR LLC | 32,163 | $807.9K | 0.00% | +13,660+73.8% | Added |
| Public Employees Retirement System of Ohio | 32,448 | $815.1K | 0.00% | −1,231−3.7% | Reduced |
| Vontobel Holding Ltd. | 34,039 | $855.1K | 0.00% | +34,039 | New |
| Alliancebernstein L.P. | 34,530 | $867.4K | 0.00% | −46,075−57.2% | Reduced |
| Handelsbanken Fonder AB | 35,400 | $889.0K | 0.00% | −3,700−9.5% | Reduced |
| Guggenheim Capital LLC | 36,647 | $920.6K | 0.01% | +2,813+8.3% | Added |
| Stifel Financial Corp | 36,661 | $920.9K | 0.00% | +36,661 | New |
| Prelude Capital Management, LLC | 38,521 | $967.6K | 0.07% | +38,521 | New |
| CWM, LLC | 41,880 | $1.05M | 0.00% | −52,353−55.6% | Reduced |
| Panagora Asset Management Inc | 42,134 | $1.06M | 0.00% | +42,134 | New |
| Voya Investment Management LLC | 43,661 | $1.10M | 0.00% | −129,273−74.8% | Reduced |
| Treasurer of the State of North Carolina | 45,170 | $1.14M | 0.00% | −3,296−6.8% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 46,009 | $1.16M | 0.01% | −2,361−4.9% | Reduced |
| Elmind Capital, LP | 50,000 | $1.26M | 0.37% | +50,000 | New |
| Ishara Investments LP | 50,000 | $1.26M | 1.46% | +50,000 | New |
| Jane Street Group, LLC | 50,114 | $1.26M | 0.00% | −243,085−82.9% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 51,933 | $1.30M | 0.05% | +3,804+7.9% | Added |
| The PNC Financial Services Group, Inc. | 53,526 | $1.34M | 0.00% | −526−1.0% | Reduced |
| PDT Partners, LLC | 53,951 | $1.36M | 0.09% | 00.0% | Unchanged |
| SEI Investments Co | 60,291 | $1.51M | 0.00% | −94,831−61.1% | Reduced |
| Profund Advisors LLC | 61,832 | $1.55M | 0.05% | +27,120+78.1% | Added |
| Balyasny Asset Management LLC | 65,133 | $1.64M | 0.00% | +65,133 | New |
| State of Wisconsin Investment Board | 66,916 | $1.68M | 0.00% | −18,845−22.0% | Reduced |
| Raymond James Financial Inc | 66,997 | $1.68M | 0.00% | −10,681−13.8% | Reduced |
| Ikarian Capital, LLC | 71,747 | $1.80M | 0.23% | −380,155−84.1% | Reduced |
| California State Teachers Retirement System | 73,203 | $1.84M | 0.00% | −95−0.1% | Reduced |
| Coppell Advisory Solutions LLC | 77,390 | $1.95M | 0.20% | +77,390 | New |
| Steward Partners Investment Advisory, LLC | 81,698 | $2.05M | 0.01% | −32,390−28.4% | Reduced |
| Legal & General Group Plc | 85,489 | $2.15M | 0.00% | −6,903−7.5% | Reduced |
| Winton Group Ltd | 86,653 | $2.18M | 0.08% | +86,653 | New |
| Royal Bank of Canada | 88,687 | $2.23M | 0.00% | −57,520−39.3% | Reduced |
| Price T Rowe Associates Inc | 95,035 | $2.39M | 0.00% | −2,905−3.0% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 95,755 | $2.41M | 0.00% | +49,642+107.7% | Added |
| State Board of Administration of Florida Retirement System | 96,125 | $2.41M | 0.00% | +530+0.6% | Added |
| Mackenzie Financial Corp | 96,211 | $2.42M | 0.00% | +19,500+25.4% | Added |
| Edgestream Partners, L.P. | 97,443 | $2.45M | 0.07% | −32,308−24.9% | Reduced |
| Alps Advisors Inc | 103,696 | $2.60M | 0.02% | +40,881+65.1% | Added |
| Wells Fargo & Company | 103,815 | $2.61M | 0.00% | +101,352+4,115.0% | Added |
| New York State Common Retirement Fund | 104,018 | $2.61M | 0.00% | +55,181+113.0% | Added |
| Algert Global LLC | 109,733 | $2.76M | 0.04% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 110,900 | $2.79M | 0.01% | +110,900 | New |
| Rhumbline Advisers | 116,917 | $2.94M | 0.00% | −512−0.4% | Reduced |
| Exome Asset Management LLC | 135,849 | $3.41M | 1.69% | +135,849 | New |
| ING Groep NV | 139,000 | $3.49M | 0.02% | −1,035,500−88.2% | Reduced |
| DekaBank Deutsche Girozentrale | 55,000 | $3.50M | 0.01% | 00.0% | Unchanged |
| Bridgewater Associates, LP | 143,805 | $3.61M | 0.01% | +143,805 | New |