Apellis Pharmaceuticals, Inc.
APLSDelisted May 14, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 273
- +31 vs. Q2 2025
- Shares held
- 122.3M
- −5.96M (−4.6%) vs. Q2 2025
- Total value
- $2.77B
- +$549.5M (+24.7%) vs. Q2 2025
- New holders
- 61
- 92 more added
- Sold out
- 30
- 91 more reduced
5 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.28B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.04B |
| Q3 2024 | 265 | $3.41B |
| Q2 2024 | 263 | $4.43B |
| Q1 2024 | 302 | $6.65B |
| Q4 2023 | 284 | $6.82B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.71B |
| Q1 2023 | 282 | $7.28B |
| Q4 2022 | 244 | $5.20B |
| Q3 2022 | 250 | $6.66B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.83B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.08B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EFG Asset Management (North America) Corp. | 155,399 | $3.52M | 0.45% | +50,375+48.0% | Added |
| Bank of Montreal | 160,306 | $3.63M | 0.00% | +693+0.4% | Added |
| Y-Intercept (Hong Kong) Ltd | 163,813 | $3.71M | 0.09% | −462−0.3% | Reduced |
| UBS Asset Management Americas Inc | 167,464 | $3.79M | 0.00% | −134,475−44.5% | Reduced |
| Rafferty Asset Management, LLC | 168,352 | $3.81M | 0.01% | +24,500+17.0% | Added |
| Voya Investment Management LLC | 172,934 | $3.91M | 0.00% | +22,341+14.8% | Added |
| Schroder Investment Management Group | 173,087 | $3.92M | 0.00% | −312,528−64.4% | Reduced |
| Boothbay Fund Management, LLC | 179,226 | $4.06M | 0.10% | +156,229+679.3% | Added |
| Invesco Ltd. | 183,016 | $4.14M | 0.00% | +16,881+10.2% | Added |
| Silvercrest Asset Management Group LLC | 190,526 | $4.31M | 0.03% | +190,526 | New |
| ExodusPoint Capital Management, LP | 194,758 | $4.41M | 0.06% | +194,758 | New |
| Fiduciary Trust Co | 198,179 | $4.48M | 0.05% | −4,357−2.2% | Reduced |
| Canada Pension Plan Investment Board | 217,000 | $4.91M | 0.00% | −119,800−35.6% | Reduced |
| Point72 Asset Management, L.P. | 217,071 | $4.91M | 0.01% | +217,071 | New |
| Rhenman & Partners Asset Management AB | 232,250 | $5.26M | 0.58% | +139,000+149.1% | Added |
| Readystate Asset Management LP | 241,977 | $5.48M | 0.27% | +241,977 | New |
| Bank of New York Mellon Corp | 248,194 | $5.62M | 0.00% | +4,867+2.0% | Added |
| Integral Health Asset Management, LLC | 250,000 | $5.66M | 0.41% | +250,000 | New |
| Jefferies Financial Group Inc. | 251,555 | $5.69M | 0.05% | −326,650−56.5% | Reduced |
| Two Sigma Investments, LP | 252,068 | $5.70M | 0.01% | −154,845−38.1% | Reduced |
| Barclays PLC | 269,527 | $6.10M | 0.00% | −4,385−1.6% | Reduced |
| Jump Financial, LLC | 277,648 | $6.28M | 0.08% | −281,020−50.3% | Reduced |
| J. Goldman & Co LP | 283,153 | $6.41M | 0.24% | +189,579+202.6% | Added |
| 683 Capital Management, LLC | 288,000 | $6.52M | 0.59% | −122,000−29.8% | Reduced |
| Jane Street Group, LLC | 293,199 | $6.64M | 0.01% | +47,000+19.1% | Added |
| Ieq Capital, LLC | 296,784 | $6.72M | 0.02% | −50,139−14.5% | Reduced |
| Cubist Systematic Strategies, LLC | 299,783 | $6.78M | 0.10% | +299,783 | New |
| Caption Management, LLC | 305,000 | $6.90M | 0.40% | +74,112+32.1% | Added |
| Susquehanna International Group, LLP | 313,884 | $7.10M | 0.01% | −14,842−4.5% | Reduced |
| HRT Financial LP | 353,649 | $8.00M | 0.03% | +246,449+229.9% | Added |
| Pictet Asset Management Holding SA | 363,450 | $8.23M | 0.01% | +15,101+4.3% | Added |
| Marshall Wace, LLP | 396,735 | $8.98M | 0.01% | −2,308,102−85.3% | Reduced |
| SG Americas Securities, LLC | 417,392 | $9.45M | 0.03% | +372,289+825.4% | Added |
| Hudson Bay Capital Management LP | 418,500 | $9.47M | 0.06% | −56,500−11.9% | Reduced |
| Citigroup Inc | 444,972 | $10.1M | 0.01% | +306,521+221.4% | Added |
| Ikarian Capital, LLC | 451,902 | $10.2M | 2.32% | +376,902+502.5% | Added |
| D. E. Shaw & Co., Inc. | 456,791 | $10.3M | 0.01% | +205,722+81.9% | Added |
| Woodline Partners LP | 542,981 | $12.3M | 0.06% | +12,058+2.3% | Added |
| Northern Trust Corp | 549,248 | $12.4M | 0.00% | +23,366+4.4% | Added |
| Ossiam | 555,953 | $12.6M | 0.16% | 00.0% | Unchanged |
| Citadel Advisors LLC | 586,452 | $13.3M | 0.01% | +143,892+32.5% | Added |
| Trexquant Investment LP | 586,939 | $13.3M | 0.14% | +259,518+79.3% | Added |
| Los Angeles Capital Management LLC | 620,790 | $14.0M | 0.05% | +620,790 | New |
| Charles Schwab Investment Management Inc | 647,082 | $14.6M | 0.00% | −342,061−34.6% | Reduced |
| Nuveen, LLC | 665,048 | $15.1M | 0.00% | +195,795+41.7% | Added |
| Ameriprise Financial Inc | 717,703 | $16.2M | 0.00% | −32,458−4.3% | Reduced |
| Renaissance Technologies LLC | 722,895 | $16.4M | 0.02% | +711,907+6,478.9% | Added |
| Kynam Capital Management, LP | 808,607 | $18.3M | 1.36% | +808,607 | New |
| Octagon Capital Advisors LP | 903,500 | $20.4M | 3.19% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 972,474 | $22.0M | 0.02% | −325,985−25.1% | Reduced |
| Voloridge Investment Management, LLC | 992,269 | $22.5M | 0.08% | +523,559+111.7% | Added |
| ING Groep NV | 1,174,500 | $26.6M | 0.14% | +866,200+281.0% | Added |
| Millennium Management LLC | 1,343,726 | $30.4M | 0.02% | +1,141,274+563.7% | Added |
| Bank of Nova Scotia | 1,456,225 | $33.0M | 0.06% | +861,413+144.8% | Added |
| Bank of America Corp | 1,477,525 | $33.4M | 0.00% | −949,103−39.1% | Reduced |
| Deutsche Bank AG | 1,504,457 | $34.0M | 0.01% | +8,161+0.5% | Added |
| Amundi | 1,493,678 | $36.4M | 0.01% | −110,427−6.9% | Reduced |
| Geode Capital Management, LLC | 2,072,913 | $46.9M | 0.00% | +77,642+3.9% | Added |
| OrbiMed Advisors LLC | 2,323,368 | $52.6M | 1.26% | +841,068+56.7% | Added |
| Siren, L.L.C. | 2,578,396 | $58.3M | 2.28% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 2,650,230 | $60.0M | 0.29% | +1,298,055+96.0% | Added |
| Suvretta Capital Management, LLC | 2,878,000 | $65.1M | 1.97% | 00.0% | Unchanged |
| UBS Group AG | 3,429,905 | $77.6M | 0.02% | −1,305,406−27.6% | Reduced |
| EcoR1 Capital, LLC | 3,447,156 | $78.0M | 3.75% | −8,448,652−71.0% | Reduced |
| State Street Corp | 4,037,644 | $91.4M | 0.00% | +474,923+13.3% | Added |
| Jennison Associates LLC | 4,348,055 | $98.4M | 0.06% | +1,686,232+63.3% | Added |
| AQR Capital Management LLC | 4,487,354 | $101.5M | 0.07% | −1,489,060−24.9% | Reduced |
| BlackRock, Inc. | 6,268,465 | $141.9M | 0.00% | −136,534−2.1% | Reduced |
| Deep Track Capital, LP | 8,000,382 | $181.0M | 5.05% | +1,000,382+14.3% | Added |
| Wellington Management Group LLP | 9,290,960 | $210.3M | 0.04% | +313,998+3.5% | Added |
| Morgan Stanley | 9,643,248 | $218.2M | 0.01% | −108,953−1.1% | Reduced |
| Vanguard Group Inc | 9,987,394 | $226.0M | 0.00% | −167,357−1.6% | Reduced |
| Avoro Capital Advisors LLC | 12,222,222 | $276.6M | 3.58% | 00.0% | Unchanged |
| Braidwell LP | 0 | $0 | 0.00% | −1,121,034−100.0% | Sold out |
| Capitolis Liquid Global Markets LLC | 0 | $0 | 0.00% | −544,600−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −256,800−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −154,010−100.0% | Sold out |
| Connor, Clark & Lunn Investment Management Ltd. | 0 | $0 | 0.00% | −118,724−100.0% | Sold out |
| Dark Forest Capital Management LP | 0 | $0 | 0.00% | −104,725−100.0% | Sold out |
| Exome Asset Management LLC | 0 | $0 | 0.00% | −98,600−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −95,605−100.0% | Sold out |
| Phocas Financial Corp. | 0 | $0 | 0.00% | −71,599−100.0% | Sold out |
| Healthcare of Ontario Pension Plan Trust Fund | 0 | $0 | 0.00% | −56,000−100.0% | Sold out |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −47,700−100.0% | Sold out |
| Wealthedge Investment Advisors, LLC | 0 | $0 | 0.00% | −38,572−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −31,139−100.0% | Sold out |
| First Trust Advisors LP | 0 | $0 | 0.00% | −26,538−100.0% | Sold out |
| Parallax Volatility Advisers, L.P. | 0 | $0 | 0.00% | −24,443−100.0% | Sold out |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −23,437−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −21,168−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −16,798−100.0% | Sold out |
| 111 Capital | 0 | $0 | 0.00% | −12,400−100.0% | Sold out |
| Eastern Bank | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Wexford Capital LP | 0 | $0 | 0.00% | −9,139−100.0% | Sold out |
| Headlands Technologies LLC | 0 | $0 | 0.00% | −6,892−100.0% | Sold out |
| Lazard Asset Management LLC | 0 | $0 | 0.00% | −1,024−100.0% | Sold out |
| Future Financial Wealth Managment LLC | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| Quintet Private Bank (Europe) S.A. | 0 | $0 | 0.00% | −452−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −241−100.0% | Sold out |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −152−100.0% | Sold out |