Apellis Pharmaceuticals, Inc.
APLSDelisted May 14, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 273
- +31 vs. Q2 2025
- Shares held
- 122.3M
- −5.96M (−4.6%) vs. Q2 2025
- Total value
- $2.77B
- +$549.5M (+24.7%) vs. Q2 2025
- New holders
- 61
- 92 more added
- Sold out
- 30
- 91 more reduced
5 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.28B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.04B |
| Q3 2024 | 265 | $3.41B |
| Q2 2024 | 263 | $4.43B |
| Q1 2024 | 302 | $6.65B |
| Q4 2023 | 284 | $6.82B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.71B |
| Q1 2023 | 282 | $7.28B |
| Q4 2022 | 244 | $5.20B |
| Q3 2022 | 250 | $6.66B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.83B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.08B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Xponance, Inc. | 17,483 | $395.6K | 0.00% | −875−4.8% | Reduced |
| Essential Partners LLC | 17,759 | $401.9K | 0.13% | −6,143−25.7% | Reduced |
| Great West Life Assurance Co | 17,747 | $402.0K | 0.00% | +11,558+186.8% | Added |
| Concentric Capital Strategies, LP | 17,979 | $406.9K | 0.02% | +17,979 | New |
| Buckingham Strategic Partners | 19,919 | $409.3K | 0.00% | −4,431−18.2% | Reduced |
| Corton Capital Inc. | 18,427 | $417.0K | 1.03% | −2,584−12.3% | Reduced |
| FMR LLC | 18,503 | $418.7K | 0.00% | −789−4.1% | Reduced |
| Teacher Retirement System of Texas | 18,512 | $418.9K | 0.00% | −1,775−8.7% | Reduced |
| Dimensional Fund Advisors LP | 18,690 | $423.0K | 0.00% | +18,690 | New |
| Brighton Jones LLC | 19,214 | $434.8K | 0.01% | +2,675+16.2% | Added |
| Merit Financial Group, LLC | 19,544 | $442.3K | 0.00% | −1,552−7.4% | Reduced |
| ADAR1 Capital Management, LLC | 20,000 | $452.6K | 0.04% | +3,000+17.6% | Added |
| Bayforest Capital Ltd | 20,853 | $471.9K | 0.22% | −35,786−63.2% | Reduced |
| Captrust Financial Advisors | 21,111 | $477.7K | 0.00% | −8,421−28.5% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 21,317 | $482.4K | 0.00% | +2,189+11.4% | Added |
| Capstone Investment Advisors, LLC | 21,371 | $483.6K | 0.00% | +9,671+82.7% | Added |
| Colony Group, LLC | 21,771 | $492.2K | 0.00% | −7,905−26.6% | Reduced |
| China Universal Asset Management Co., Ltd. | 22,137 | $501.0K | 0.04% | −3,106−12.3% | Reduced |
| PharVision Advisers, LLC | 22,291 | $504.4K | 0.28% | +22,291 | New |
| Arizona State Retirement System | 22,298 | $504.6K | 0.00% | +315+1.4% | Added |
| Manufacturers Life Insurance Company, The | 22,709 | $513.9K | 0.00% | +736+3.3% | Added |
| Virtus Investment Advisers, Inc. | 23,073 | $522.1K | 0.15% | 00.0% | Unchanged |
| Quest Partners LLC | 23,099 | $522.7K | 0.03% | +1,859+8.8% | Added |
| Graham Capital Management, L.P. | 23,196 | $524.9K | 0.02% | −19,895−46.2% | Reduced |
| Entropy Technologies, LP | 24,603 | $556.8K | 0.04% | +24,603 | New |
| HAP Trading, LLC | 24,763 | $560.4K | 0.15% | +24,763 | New |
| Erste Asset Management GmbH | 25,300 | $573.0K | 0.01% | −16,700−39.8% | Reduced |
| Virginia Retirement Systems Et Al | 25,465 | $576.3K | 0.00% | −2,200−8.0% | Reduced |
| Bayesian Capital Management, LP | 25,500 | $577.1K | 0.12% | +25,500 | New |
| Fox Run Management, L.L.C. | 27,223 | $616.1K | 0.10% | +13,256+94.9% | Added |
| Gsa Capital Partners LLP | 31,446 | $712.0K | 0.06% | +31,446 | New |
| Voleon Capital Management LP | 32,221 | $729.2K | 0.02% | −10,918−25.3% | Reduced |
| Pallas Capital Advisors LLC | 33,077 | $748.5K | 0.03% | −21,772−39.7% | Reduced |
| Public Employees Retirement System of Ohio | 33,679 | $762.2K | 0.00% | +209+0.6% | Added |
| Guggenheim Capital LLC | 33,834 | $765.7K | 0.01% | −4,619−12.0% | Reduced |
| Scientech Research LLC | 34,182 | $773.5K | 0.27% | +34,182 | New |
| Janus Henderson Group PLC | 34,412 | $778.7K | 0.00% | 00.0% | Unchanged |
| Profund Advisors LLC | 34,712 | $785.5K | 0.03% | +6,036+21.0% | Added |
| Vident Advisory, LLC | 35,381 | $800.7K | 0.01% | +35,381 | New |
| Creative Planning | 35,645 | $806.6K | 0.00% | +13,807+63.2% | Added |
| Nomura Holdings Inc | 36,600 | $828.3K | 0.00% | +36,600 | New |
| Point72 Hong Kong Ltd | 37,941 | $858.6K | 0.04% | +37,941 | New |
| Mercer Global Advisors Inc | 39,043 | $883.5K | 0.00% | +18,102+86.4% | Added |
| Handelsbanken Fonder AB | 39,100 | $885.0K | 0.00% | +8,900+29.5% | Added |
| Mariner, LLC | 43,239 | $978.5K | 0.00% | +6,909+19.0% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 46,113 | $1.04M | 0.00% | +20,840+82.5% | Added |
| Schonfeld Strategic Advisors LLC | 47,282 | $1.07M | 0.01% | −36,634−43.7% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 48,129 | $1.09M | 0.04% | −885−1.8% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 48,370 | $1.09M | 0.01% | +7,416+18.1% | Added |
| Quantinno Capital Management LP | 48,419 | $1.10M | 0.00% | +48,419 | New |
| Treasurer of the State of North Carolina | 48,466 | $1.10M | 0.00% | −1,892−3.8% | Reduced |
| T. Rowe Price Investment Management, Inc. | 48,756 | $1.10M | 0.00% | −552−1.1% | Reduced |
| New York State Common Retirement Fund | 48,837 | $1.11M | 0.00% | −10,042−17.1% | Reduced |
| Highland Capital Management, LLC | 50,133 | $1.13M | 0.06% | +50,133 | New |
| Natixis | 52,239 | $1.18M | 0.01% | −38,427−42.4% | Reduced |
| Squarepoint Ops LLC | 52,834 | $1.20M | 0.00% | −276,558−84.0% | Reduced |
| DekaBank Deutsche Girozentrale | 55,000 | $1.20M | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 53,516 | $1.21M | 0.00% | −181,285−77.2% | Reduced |
| Campbell & CO Investment Adviser LLC | 53,540 | $1.21M | 0.09% | +53,540 | New |
| Simplex Trading, LLC | 53,901 | $1.22M | 0.03% | −2,033−3.6% | Reduced |
| PDT Partners, LLC | 53,951 | $1.22M | 0.08% | −106,107−66.3% | Reduced |
| The PNC Financial Services Group, Inc. | 54,052 | $1.22M | 0.00% | −4,804−8.2% | Reduced |
| Alps Advisors Inc | 62,815 | $1.42M | 0.01% | −4,946−7.3% | Reduced |
| Sphera Funds Management Ltd. | 63,660 | $1.44M | 0.34% | −50,686−44.3% | Reduced |
| Macquarie Group Ltd | 65,156 | $1.47M | 0.00% | +65,156 | New |
| Engineers Gate Manager LP | 66,336 | $1.50M | 0.02% | +7,618+13.0% | Added |
| Man Group plc | 67,202 | $1.52M | 0.00% | +67,202 | New |
| J. Safra Sarasin Holding AG | 70,500 | $1.60M | 0.03% | −45,184−39.1% | Reduced |
| California State Teachers Retirement System | 73,298 | $1.66M | 0.00% | −14,631−16.6% | Reduced |
| Landscape Capital Management, L.L.C. | 75,000 | $1.70M | 0.11% | +10,479+16.2% | Added |
| Mackenzie Financial Corp | 76,711 | $1.74M | 0.00% | +2,546+3.4% | Added |
| Raymond James Financial Inc | 77,678 | $1.76M | 0.00% | +3,212+4.3% | Added |
| Bleakley Financial Group, LLC | 79,305 | $1.79M | 0.04% | +2,217+2.9% | Added |
| Alliancebernstein L.P. | 80,605 | $1.82M | 0.00% | +48,676+152.5% | Added |
| SRS Capital Advisors, Inc. | 82,067 | $1.86M | 0.03% | +82,067 | New |
| State of Wisconsin Investment Board | 85,761 | $1.94M | 0.00% | −8,643−9.2% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 77,508 | $1.95M | 0.00% | −23,158−23.0% | Reduced |
| Brevan Howard Capital Management LP | 91,021 | $2.06M | 0.03% | +91,021 | New |
| Rock Springs Capital Management LP | 92,000 | $2.08M | 0.12% | +7,700+9.1% | Added |
| Legal & General Group Plc | 92,392 | $2.09M | 0.00% | −3,658−3.8% | Reduced |
| CWM, LLC | 94,233 | $2.13M | 0.01% | −33,351−26.1% | Reduced |
| State Board of Administration of Florida Retirement System | 95,595 | $2.16M | 0.00% | +4,187+4.6% | Added |
| Price T Rowe Associates Inc | 97,940 | $2.22M | 0.00% | +5,789+6.3% | Added |
| Simplify Asset Management Inc. | 106,888 | $2.42M | 0.05% | +106,888 | New |
| Algert Global LLC | 109,733 | $2.48M | 0.04% | −44,380−28.8% | Reduced |
| Worldquant Millennium Advisors LLC | 111,979 | $2.53M | 0.01% | +111,979 | New |
| Steward Partners Investment Advisory, LLC | 114,088 | $2.58M | 0.01% | −26,887−19.1% | Reduced |
| Rhumbline Advisers | 117,429 | $2.66M | 0.00% | −4,573−3.7% | Reduced |
| Qube Research & Technologies Ltd | 120,003 | $2.72M | 0.00% | +120,003 | New |
| Goldman Sachs Group Inc | 124,373 | $2.81M | 0.00% | −91,626−42.4% | Reduced |
| Gotham Asset Management, LLC | 127,158 | $2.88M | 0.01% | +7,929+6.7% | Added |
| Cerity Partners LLC | 128,110 | $2.90M | 0.00% | +13,365+11.6% | Added |
| Edgestream Partners, L.P. | 129,751 | $2.94M | 0.09% | −88,641−40.6% | Reduced |
| Aquatic Capital Management LLC | 130,828 | $2.96M | 0.05% | −45,876−26.0% | Reduced |
| Walleye Capital LLC | 142,158 | $3.22M | 0.03% | +60,888+74.9% | Added |
| HighVista Strategies LLC | 145,729 | $3.30M | 0.81% | +59,066+68.2% | Added |
| Royal Bank of Canada | 146,207 | $3.31M | 0.00% | −651,378−81.7% | Reduced |
| California Public Employees Retirement System | 146,188 | $3.31M | 0.00% | +11,551+8.6% | Added |
| Swiss National Bank | 146,200 | $3.31M | 0.00% | +2,400+1.7% | Added |
| SEI Investments Co | 155,122 | $3.51M | 0.00% | +132,763+593.8% | Added |