Apellis Pharmaceuticals, Inc.
APLSDelisted May 14, 2026- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001492422
Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 255
- −2 vs. Q4 2024
- Shares held
- 128.0M
- +1.77M (+1.4%) vs. Q4 2024
- Total value
- $2.80B
- −$1.23B (−30.5%) vs. Q4 2024
- New holders
- 50
- 90 more added
- Sold out
- 52
- 76 more reduced
3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1 | $10.2K |
| Q1 2026 | 324 | $5.56B |
| Q4 2025 | 280 | $3.17B |
| Q3 2025 | 273 | $2.77B |
| Q2 2025 | 247 | $2.28B |
| Q1 2025 | 255 | $2.80B |
| Q4 2024 | 260 | $4.04B |
| Q3 2024 | 265 | $3.41B |
| Q2 2024 | 263 | $4.43B |
| Q1 2024 | 302 | $6.65B |
| Q4 2023 | 284 | $6.82B |
| Q3 2023 | 256 | $4.34B |
| Q2 2023 | 317 | $9.71B |
| Q1 2023 | 282 | $7.28B |
| Q4 2022 | 244 | $5.20B |
| Q3 2022 | 250 | $6.66B |
| Q2 2022 | 212 | $4.15B |
| Q1 2022 | 212 | $4.62B |
| Q4 2021 | 187 | $3.83B |
| Q3 2021 | 181 | $2.29B |
| Q2 2021 | 205 | $4.08B |
| Q1 2021 | 175 | $2.80B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Jane Street Group, LLC | 256,092 | $5.60M | 0.01% | +160,107+166.8% | Added |
| Two Sigma Investments, LP | 262,904 | $5.75M | 0.01% | +262,904 | New |
| Jump Financial, LLC | 265,593 | $5.81M | 0.09% | +265,593 | New |
| Schroder Investment Management Group | 253,109 | $6.14M | 0.01% | +33,726+15.4% | Added |
| Ieq Capital, LLC | 291,858 | $6.38M | 0.05% | +165,148+130.3% | Added |
| Goldman Sachs Group Inc | 307,709 | $6.73M | 0.00% | +64,742+26.6% | Added |
| Hudson Bay Capital Management LP | 310,700 | $6.80M | 0.04% | −34,300−9.9% | Reduced |
| Walleye Capital LLC | 317,442 | $6.94M | 0.08% | −77,381−19.6% | Reduced |
| Balyasny Asset Management LLC | 324,487 | $7.10M | 0.02% | −419,707−56.4% | Reduced |
| Bank of New York Mellon Corp | 329,173 | $7.20M | 0.00% | −5,243−1.6% | Reduced |
| 683 Capital Management, LLC | 333,000 | $7.28M | 0.74% | −27,000−7.5% | Reduced |
| Algert Global LLC | 338,613 | $7.41M | 0.18% | +56,328+20.0% | Added |
| Amundi | 329,582 | $7.42M | 0.00% | 00.0% | Unchanged |
| Pictet Asset Management Holding SA | 314,842 | $7.62M | 0.01% | −33,012−9.5% | Reduced |
| SG Americas Securities, LLC | 366,144 | $8.01M | 0.03% | +313,743+598.7% | Added |
| Trexquant Investment LP | 384,922 | $8.42M | 0.10% | +181,914+89.6% | Added |
| Citigroup Inc | 416,619 | $9.11M | 0.01% | +224,458+116.8% | Added |
| JPMorgan Chase & Co | 423,800 | $9.27M | 0.00% | +12,251+3.0% | Added |
| Squarepoint Ops LLC | 442,793 | $9.68M | 0.02% | +275,831+165.2% | Added |
| Millennium Management LLC | 451,973 | $9.88M | 0.01% | −123,517−21.5% | Reduced |
| Ameriprise Financial Inc | 466,661 | $10.2M | 0.00% | −416,140−47.1% | Reduced |
| Nuveen, LLC | 492,238 | $10.8M | 0.00% | +492,238 | New |
| Northern Trust Corp | 518,694 | $11.3M | 0.00% | −28,582−5.2% | Reduced |
| Jefferies Financial Group Inc. | 599,255 | $13.1M | 0.23% | +257,894+75.5% | Added |
| Invesco Ltd. | 641,397 | $14.0M | 0.00% | +37,741+6.3% | Added |
| Natixis | 655,027 | $14.8M | 0.09% | −215,600−24.8% | Reduced |
| Boxer Capital Management, LLC | 713,000 | $15.6M | 4.69% | −713,000−50.0% | Reduced |
| National Bank of Canada | 782,701 | $17.1M | 0.02% | −602,899−43.5% | Reduced |
| Royal Bank of Canada | 794,935 | $17.4M | 0.00% | −723,892−47.7% | Reduced |
| Charles Schwab Investment Management Inc | 964,499 | $21.1M | 0.00% | −32,249−3.2% | Reduced |
| Man Group plc | 1,027,792 | $22.5M | 0.07% | +978,500+1,985.1% | Added |
| Canada Pension Plan Investment Board | 1,048,700 | $22.9M | 0.02% | +1,013,500+2,879.3% | Added |
| BNP Paribas Arbitrage, SA | 1,110,709 | $24.3M | 0.02% | +259,886+30.5% | Added |
| OrbiMed Advisors LLC | 1,432,300 | $31.3M | 0.75% | +1,432,300 | New |
| FMR LLC | 1,503,209 | $32.9M | 0.00% | −624,456−29.3% | Reduced |
| Norges Bank | 1,573,601 | $34.4M | 0.00% | +487,358+44.9% | Added |
| Polar Capital Holdings Plc | 1,577,175 | $34.5M | 0.21% | 00.0% | Unchanged |
| Suvretta Capital Management, LLC | 1,646,615 | $36.0M | 1.46% | +853,428+107.6% | Added |
| Braidwell LP | 1,652,334 | $36.1M | 1.27% | −446,532−21.3% | Reduced |
| Deutsche Bank AG | 1,776,576 | $38.9M | 0.02% | −1,801−0.1% | Reduced |
| Geode Capital Management, LLC | 1,950,046 | $42.7M | 0.00% | +111,094+6.0% | Added |
| Octagon Capital Advisors LP | 2,094,000 | $45.8M | 9.95% | −912,980−30.4% | Reduced |
| Jennison Associates LLC | 2,477,531 | $54.2M | 0.04% | −282,873−10.2% | Reduced |
| Siren, L.L.C. | 2,578,396 | $56.4M | 3.18% | −237,862−8.4% | Reduced |
| Bank of America Corp | 3,131,436 | $68.5M | 0.01% | +1,451,223+86.4% | Added |
| UBS Group AG | 3,272,194 | $71.6M | 0.02% | +685,455+26.5% | Added |
| State Street Corp | 3,941,405 | $86.2M | 0.00% | −583,750−12.9% | Reduced |
| AQR Capital Management LLC | 4,077,419 | $89.2M | 0.09% | +2,220,977+119.6% | Added |
| Deep Track Capital, LP | 5,000,000 | $109.3M | 3.54% | +725,079+17.0% | Added |
| BlackRock, Inc. | 6,329,598 | $138.4M | 0.00% | −148,391−2.3% | Reduced |
| Morgan Stanley | 9,626,123 | $210.5M | 0.02% | −1,1040.0% | Reduced |
| Vanguard Group Inc | 10,130,356 | $221.6M | 0.00% | +84,331+0.8% | Added |
| EcoR1 Capital, LLC | 11,895,808 | $260.2M | 15.47% | +4,9650.0% | Added |
| Avoro Capital Advisors LLC | 12,222,222 | $267.3M | 4.17% | 00.0% | Unchanged |
| Wellington Management Group LLP | 12,303,252 | $269.1M | 0.05% | +502,403+4.3% | Added |
| Activest Wealth Management | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| CIBC World Markets Corp | 0 | $0 | 0.00% | −1,285,300−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −1,267,958−100.0% | Sold out |
| Logos Global Management LP | 0 | $0 | 0.00% | −500,000−100.0% | Sold out |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −420,000−100.0% | Sold out |
| MUFG Securities EMEA plc | 0 | $0 | 0.00% | −298,000−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −271,913−100.0% | Sold out |
| Intrinsic Edge Capital Management LLC | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Point72 Europe (London) LLP | 0 | $0 | 0.00% | −192,694−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −191,687−100.0% | Sold out |
| Capital Fund Management S.A. | 0 | $0 | 0.00% | −121,433−100.0% | Sold out |
| Exome Asset Management LLC | 0 | $0 | 0.00% | −119,467−100.0% | Sold out |
| Banque Pictet & Cie SA | 0 | $0 | 0.00% | −97,299−100.0% | Sold out |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −86,991−100.0% | Sold out |
| Fieldview Capital Management, LLC | 0 | $0 | 0.00% | −61,405−100.0% | Sold out |
| Affinity Asset Advisors, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| TD Asset Management Inc | 0 | $0 | 0.00% | −38,692−100.0% | Sold out |
| Readystate Asset Management LP | 0 | $0 | 0.00% | −35,561−100.0% | Sold out |
| Savant Capital, LLC | 0 | $0 | 0.00% | −31,525−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −31,255−100.0% | Sold out |
| Sippican Capital Advisors | 0 | $0 | 0.00% | −20,753−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Syon Capital LLC | 0 | $0 | 0.00% | −19,455−100.0% | Sold out |
| Creative Planning | 0 | $0 | 0.00% | −16,214−100.0% | Sold out |
| Vident Advisory, LLC | 0 | $0 | 0.00% | −14,564−100.0% | Sold out |
| Entropy Technologies, LP | 0 | $0 | 0.00% | −13,960−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −11,258−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −10,680−100.0% | Sold out |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −9,937−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −9,785−100.0% | Sold out |
| Inceptionr LLC | 0 | $0 | 0.00% | −9,217−100.0% | Sold out |
| Principal Financial Group Inc | 0 | $0 | 0.00% | −9,094−100.0% | Sold out |
| DnB Asset Management AS | 0 | $0 | 0.00% | −8,853−100.0% | Sold out |
| Kovitz Investment Group Partners, LLC | 0 | $0 | 0.00% | −8,394−100.0% | Sold out |
| KPP Advisory Services LLC | 0 | $0 | 0.00% | −8,151−100.0% | Sold out |
| Point72 (DIFC) Ltd | 0 | $0 | 0.00% | −8,009−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −7,835−100.0% | Sold out |
| JustInvest LLC | 0 | $0 | 0.00% | −7,832−100.0% | Sold out |
| Corton Capital Inc. | 0 | $0 | 0.00% | −7,595−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −7,157−100.0% | Sold out |
| Nomura Holdings Inc | 0 | $0 | 0.00% | −7,000−100.0% | Sold out |
| M&T Bank Corp | 0 | $0 | 0.00% | −6,768−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −261−100.0% | Sold out |
| Colonial Trust Co | 0 | $0 | 0.00% | −258−100.0% | Sold out |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 0 | $0 | 0.00% | −220−100.0% | Sold out |