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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2023

Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
282
+41 vs. Q4 2022
Shares held
110.4M
+9.95M (+9.9%) vs. Q4 2022
Total value
$7.28B
+$2.09B (+40.2%) vs. Q4 2022
New holders
68
106 more added
Sold out
27
78 more reduced

3 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 282 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ1 2023: $7.28B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2022.

Institutions holding APLS in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Marshall Wace, LLP92,446$6.10M0.02%−343,977−78.8%Reduced
J. Goldman & Co LP91,025$6.00M0.35%+91,025New
Legal & General Group Plc86,668$5.72M0.00%+6,274+7.8%Added
Lisanti Capital Growth, LLC85,510$5.64M0.79%+29,815+53.5%Added
Credit Suisse AG83,948$5.54M0.01%+7,040+9.2%Added
Canada Pension Plan Investment Board82,300$5.43M0.01%00.0%Unchanged
Susquehanna International Group, LLP81,796$5.40M0.01%+50,064+157.8%Added
State of Wisconsin Investment Board81,584$5.38M0.02%−6,574−7.5%Reduced
Ameriprise Financial Inc79,673$5.26M0.00%+22,033+38.2%Added
Tri Locum Partners LP77,048$5.08M1.55%−144,849−65.3%Reduced
Pier Capital, LLC76,066$5.02M0.76%+849+1.1%Added
Schonfeld Strategic Advisors LLC76,027$5.01M0.05%+59,627+363.6%Added
Moore Capital Management, LP75,000$4.95M0.15%+65,000+650.0%Added
Lombard Odier Asset Management (Switzerland) SA71,180$4.70M0.41%−99,173−58.2%Reduced
Voloridge Investment Management, LLC66,235$4.37M0.02%+66,235New
Jane Street Group, LLC63,384$4.18M0.01%+49,363+352.1%Added
Raymond James & Associates61,528$4.06M0.00%+47,091+326.2%Added
The PNC Financial Services Group, Inc.61,465$4.05M0.00%+510+0.8%Added
Baird Financial Group, Inc.60,869$4.01M0.01%+21,392+54.2%Added
DAFNA Capital Management LLC57,746$3.81M1.14%−25,700−30.8%Reduced
CIBC Private Wealth Group, LLC56,985$3.76M0.01%+56,985New
State of New Jersey Common Pension Fund D55,095$3.63M0.01%−2,808−4.8%Reduced
Teachers Retirement System of the State of Kentucky54,732$3.61M0.04%−23,754−30.3%Reduced
SEI Investments Co51,195$3.38M0.01%+40,399+374.2%Added
Mirae Asset Global Investments Co., Ltd.50,462$3.33M0.01%+5,283+11.7%Added
Hudson Bay Capital Management LP50,000$3.30M0.04%+50,000New
MetLife Investment Management49,075$3.24M0.02%−590−1.2%Reduced
Picton Mahoney Asset Management48,775$3.22M0.16%+15,249+45.5%Added
First Trust Advisors LP48,322$3.19M0.00%−4,458−8.4%Reduced
American International Group, Inc.45,261$2.99M0.02%+900+2.0%Added
Amundi36,873$2.85M0.00%+11,035+42.7%Added
Algert Global LLC42,699$2.82M0.13%+9,468+28.5%Added
Neuberger Berman Group LLC40,748$2.69M0.00%−14,750−26.6%Reduced
Erste Asset Management GmbH39,650$2.62M0.05%+2,650+7.2%Added
HighVista Strategies LLC39,111$2.58M2.10%00.0%Unchanged
Guggenheim Capital LLC35,992$2.37M0.02%−12,815−26.3%Reduced
Calamos Advisors LLC35,645$2.35M0.01%+35,645New
Lazard Asset Management LLC35,304$2.33M0.00%−49,516−58.4%Reduced
Affinity Asset Advisors, LLC35,000$2.31M0.89%+35,000New
International Biotechnology Trust PLC31,700$2.09M0.58%00.0%Unchanged
Ensign Peak Advisors, Inc29,930$1.97M0.00%−133,500−81.7%Reduced
Skandinaviska Enskilda Banken AB (publ)29,441$1.94M0.01%−1,405−4.6%Reduced
State Board of Administration of Florida Retirement System28,116$1.85M0.00%00.0%Unchanged
Clough Capital Partners L P27,879$1.84M0.20%−730−2.6%Reduced
Teacher Retirement System of Texas27,251$1.80M0.01%+249+0.9%Added
Mutual of America Capital Management LLC26,852$1.77M0.02%−1,237−4.4%Reduced
Arizona State Retirement System25,631$1.69M0.02%+830+3.3%Added
Principal Financial Group Inc25,540$1.68M0.00%−47,442−65.0%Reduced
Parkman Healthcare Partners LLC25,000$1.65M0.36%+25,000New
EFG Asset Management (North America) Corp.24,031$1.58M0.35%−1,346−5.3%Reduced
ExodusPoint Capital Management, LP23,068$1.52M0.02%+8,276+55.9%Added
Axiom Investors LLC21,795$1.44M0.02%−3,553−14.0%Reduced
Profund Advisors LLC21,694$1.43M0.09%+8,972+70.5%Added
Monashee Investment Management LLC21,259$1.40M0.39%+21,259New
Boothbay Fund Management, LLC21,058$1.39M0.04%+21,058New
Knights of Columbus Asset Advisors LLC20,974$1.38M0.14%+2,283+12.2%Added
Envestnet Asset Management Inc20,744$1.37M0.00%+20,744New
Cubist Systematic Strategies, LLC20,469$1.35M0.01%+20,469New
ProShare Advisors LLC18,974$1.25M0.00%−3,663−16.2%Reduced
Allianz Asset Management GmbH18,000$1.19M0.00%+18,000New
Bayesian Capital Management, LP17,924$1.18M0.15%+17,924New
HSBC Holdings PLC17,530$1.17M0.00%+17,530New
Mackenzie Financial Corp17,662$1.16M0.00%+7,360+71.4%Added
Brinker Capital Investments, LLC17,325$1.14M0.01%+17,325New
Orion Portfolio Solutions, LLC17,325$1.14M0.01%+17,325New
PDT Partners, LLC16,824$1.11M0.15%+16,824New
Stifel Financial Corp16,718$1.10M0.00%+9,508+131.9%Added
Panagora Asset Management Inc16,231$1.07M0.01%00.0%Unchanged
Natixis15,700$1.04M0.01%−329,300−95.4%Reduced
AQR Capital Management LLC15,189$1.00M0.00%−2,002−11.6%Reduced
Handelsbanken Fonder AB15,000$989.0K0.01%+3,000+25.0%Added
Creative Planning14,638$965.5K0.00%+551+3.9%Added
Advisor Group Holdings, Inc.14,237$938.8K0.00%+10,988+338.2%Added
Capital Impact Advisors, LLC13,934$919.1K1.13%−25−0.2%Reduced
Amalgamated Bank13,294$877.0K0.01%−2,109−13.7%Reduced
STRS Ohio12,200$804.0K0.00%+1,800+17.3%Added
Inspire Advisors, LLC12,151$801.5K0.18%+12,151New
Birchview Capital, LP12,000$792.0K0.62%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)11,661$769.2K0.00%+1,026+9.6%Added
Raymond James Financial Services Advisors, Inc.11,412$752.7K0.00%−6−0.1%Reduced
Hennion & Walsh Asset Management, Inc.11,346$748.0K0.05%+1,928+20.5%Added
Stonnington Group, LLC9,400$744.1K0.19%+9,400New
Sippican Capital Advisors11,169$736.7K0.70%+11,169New
SG Americas Securities, LLC11,063$730.0K0.01%−20,319−64.7%Reduced
Virginia Retirement Systems Et Al10,800$712.4K0.01%−4,200−28.0%Reduced
Walleye Trading LLC10,724$707.4K0.03%+10,724New
Cambridge Trust Co10,000$659.6K0.03%00.0%Unchanged
Nisa Investment Advisors, LLC9,860$650.0K0.01%+12+0.1%Added
Public Employees Retirement Association of Colorado9,749$643.0K0.00%00.0%Unchanged
Stock Yards Bank & Trust Co9,532$629.0K0.02%−1,683−15.0%Reduced
Keybank National Association8,373$552.3K0.00%00.0%Unchanged
Campbell & CO Investment Adviser LLC8,305$547.8K0.10%+8,305New
PAX Financial Group, LLC8,182$539.7K0.13%+8,182New
FORA Capital, LLC7,911$521.8K0.05%+7,911New
Ameritas Investment Partners, Inc.7,386$487.2K0.02%+33+0.4%Added
Pictet & Cie (Europe) SA7,341$484.2K0.02%+79+1.1%Added
Oppenheimer & Co Inc7,340$484.1K0.01%−175−2.3%Reduced
Legato Capital Management LLC6,961$459.1K0.08%00.0%Unchanged
Henshaw Capital LLC6,892$454.6K0.03%00.0%Unchanged
Oppenheimer Asset Management Inc.6,325$417.2K0.01%+6,325New