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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2023

Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
282
+41 vs. Q4 2022
Shares held
110.4M
+9.95M (+9.9%) vs. Q4 2022
Total value
$7.28B
+$2.09B (+40.2%) vs. Q4 2022
New holders
68
106 more added
Sold out
27
78 more reduced

3 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 282 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ1 2023: $7.28B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2022.

Institutions holding APLS in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Oliver Lagore Vanvalin Investment Group1$660.00%+1New
Institutional & Family Asset Management, LLC4$2640.00%00.0%Unchanged
Global Retirement Partners, LLC6$5100.00%+6New
Baker Avenue Asset Management, LP13$8570.00%00.0%Unchanged
Farther Finance Advisors, LLC13$8570.00%00.0%Unchanged
Capital Advisors, Ltd. LLC8$1.00K0.00%00.0%Unchanged
Massmutual Trust Co FSB19$1.25K0.00%00.0%Unchanged
Allworth Financial LP21$1.39K0.00%−29−58.0%Reduced
Park Place Capital Corp23$1.52K0.00%+23New
Harvest Group Wealth Management, LLC30$1.98K0.00%+3+11.1%Added
Key Financial Inc38$2.51K0.00%00.0%Unchanged
Whittier Trust Co of Nevada Inc38$2.51K0.00%+38New
Carolinas Wealth Consulting LLC39$2.56K0.00%+39New
Bell Investment Advisors, Inc58$3.83K0.00%+8+16.0%Added
Leonteq Securities AG62$4.09K0.00%+62New
CWM, LLC71$5.00K0.00%−4−5.3%Reduced
Parallax Volatility Advisers, L.P.89$5.87K0.00%−31,791−99.7%Reduced
Hanseatic Management Services Inc85$6.00K0.01%00.0%Unchanged
Geneos Wealth Management Inc.100$6.60K0.00%00.0%Unchanged
Signaturefd, LLC109$7.19K0.00%+34+45.3%Added
Northwestern Mutual Wealth Management Co116$7.65K0.00%+116New
Quadrant Capital Group LLC123$8.11K0.00%+123New
Quintet Private Bank (Europe) S.A.152$10.0K0.00%+152New
Covestor Ltd169$11.0K0.01%00.0%Unchanged
Itau Unibanco Holding S.A.179$11.8K0.00%00.0%Unchanged
Belpointe Asset Management LLC224$14.8K0.00%+224New
AdvisorNet Financial, Inc270$17.8K0.00%+270New
Lindbrook Capital, LLC276$18.2K0.00%−6−2.1%Reduced
TCI Wealth Advisors, Inc.308$20.3K0.00%−90−22.6%Reduced
Baillie Gifford & Co325$21.4K0.00%+42+14.8%Added
First Horizon Advisors, Inc.355$23.4K0.00%+355New
Clearstead Advisors, LLC405$26.7K0.00%+405New
Daiwa Securities Group Inc.445$29.0K0.00%00.0%Unchanged
Jacob Asset Management of New York LLC544$35.9K0.04%−3,500−86.5%Reduced
IFP Advisors, Inc1,985$39.0K0.00%+1,981+49,525.0%Added
Ci Investments Inc.825$54.0K0.00%+686+493.5%Added
S.A. Mason LLC925$61.0K0.04%−1,435−60.8%Reduced
Parallel Advisors, LLC942$62.1K0.00%+868+1,173.0%Added
US Bancorp1,311$86.5K0.00%+597+83.6%Added
Harbor Investment Advisory, LLC1,333$87.9K0.01%00.0%Unchanged
China Universal Asset Management Co., Ltd.2,366$156.1K0.05%+1,243+110.7%Added
Jefferies Financial Group Inc.2,475$163.3K0.00%+2,475New
Tower Research Capital LLC (TRC)2,571$170.0K0.01%+1,712+199.3%Added
Union Investments & Development Ltd.3,000$197.9K0.11%00.0%Unchanged
Weiss Multi-Strategy Advisers LLC3,373$222.0K0.01%+3,373New
HC Advisors, LLC3,378$222.8K0.14%−2,347−41.0%Reduced
CWA Asset Management Group, LLC3,400$224.3K0.02%+3,400New
Prime Capital Investment Advisors, LLC3,400$224.3K0.01%+3,400New
Simplex Trading, LLC3,423$225.0K0.01%+3,423New
Cutler Group LP3,500$230.0K0.04%+3,225+1,172.7%Added
Verition Fund Management LLC3,650$240.8K0.00%+3,650New
Level Four Advisory Services, LLC3,678$242.6K0.02%+3,678New
Veritable, L.P.3,683$242.9K0.00%+3,683New
Nelson, Van Denburg & Campbell Wealth Management Group, LLC3,795$250.3K0.02%+413+12.2%Added
Gotham Asset Management, LLC3,852$254.1K0.01%+3,852New
Compagnie Lombard Odier SCmA4,000$263.8K0.01%−500−11.1%Reduced
Sandia Investment Management LP4,000$263.8K0.05%+4,000New
Alberta Investment Management Corp4,015$264.8K0.00%+4,015New
O'Shaughnessy Asset Management, LLC4,139$273.0K0.00%+5+0.1%Added
IMA Wealth, Inc.4,150$273.7K0.07%00.0%Unchanged
Man Group plc–$274.1K0.00%––
Great West Life Assurance Co4,232$280.0K0.00%−286−6.3%Reduced
JustInvest LLC4,260$281.0K0.01%−1,961−31.5%Reduced
Harbor Capital Advisors, Inc.4,371$288.3K0.08%−88−2.0%Reduced
Cim Investment Mangement Inc4,744$312.9K0.12%+163+3.6%Added
Assetmark, Inc4,810$317.3K0.00%+4,810New
CWM Advisors, LLC4,812$317.4K0.04%+4,812New
Nebula Research & Development LLC4,821$318.0K0.56%+4,821New
Group One Trading, L.P.4,910$323.9K0.02%−45,913−90.3%Reduced
Mariner, LLC5,058$334.0K0.00%+5,058New
Metropolitan Life Insurance Co5,066$334.2K0.02%−697−12.1%Reduced
Commonwealth Equity Services, LLC5,395$355.0K0.00%+5,395New
Crown Wealth Group, LLC5,400$356.2K0.30%−6,414−54.3%Reduced
Xponance, Inc.5,415$357.2K0.01%+46+0.9%Added
Stelac Advisory Services LLC5,520$364.1K0.16%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd5,576$367.8K0.04%+5,576New
Virtus ETF Advisers LLC5,847$385.7K0.21%+104+1.8%Added
Snowden Capital Advisors LLC5,854$386.1K0.02%+5,854New
Wolverine Trading, LLC5,966$394.0K0.01%+5,966New
NJ State Employees Deferred Compensation Plan6,000$395.8K0.06%00.0%Unchanged
E Fund Management Co., Ltd.6,207$409.0K0.03%−2,397−27.9%Reduced
MML Investors Services, LLC6,202$409.0K0.00%+2,172+53.9%Added
Oppenheimer Asset Management Inc.6,325$417.2K0.01%+6,325New
Henshaw Capital LLC6,892$454.6K0.03%00.0%Unchanged
Legato Capital Management LLC6,961$459.1K0.08%00.0%Unchanged
Oppenheimer & Co Inc7,340$484.1K0.01%−175−2.3%Reduced
Pictet & Cie (Europe) SA7,341$484.2K0.02%+79+1.1%Added
Ameritas Investment Partners, Inc.7,386$487.2K0.02%+33+0.4%Added
FORA Capital, LLC7,911$521.8K0.05%+7,911New
PAX Financial Group, LLC8,182$539.7K0.13%+8,182New
Campbell & CO Investment Adviser LLC8,305$547.8K0.10%+8,305New
Keybank National Association8,373$552.3K0.00%00.0%Unchanged
Stock Yards Bank & Trust Co9,532$629.0K0.02%−1,683−15.0%Reduced
Public Employees Retirement Association of Colorado9,749$643.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC9,860$650.0K0.01%+12+0.1%Added
Cambridge Trust Co10,000$659.6K0.03%00.0%Unchanged
Walleye Trading LLC10,724$707.4K0.03%+10,724New
Virginia Retirement Systems Et Al10,800$712.4K0.01%−4,200−28.0%Reduced
SG Americas Securities, LLC11,063$730.0K0.01%−20,319−64.7%Reduced
Sippican Capital Advisors11,169$736.7K0.70%+11,169New