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Apellis Pharmaceuticals, Inc.

APLSDelisted May 14, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001492422

Apellis Pharmaceuticals, Inc. was delisted on May 14, 2026; its insiders filed their last Form 4 on May 14, 2026; 324 institutions reported holding it in 13F filings for Q1 2026, worth $5.56B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2022

Institutional positions in Apellis Pharmaceuticals, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
212
+28 vs. Q4 2021
Shares held
91.0M
+10.1M (+12.5%) vs. Q4 2021
Total value
$4.62B
+$799.1M (+20.9%) vs. Q4 2021
New holders
52
73 more added
Sold out
24
64 more reduced

3 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 212 institutions
Q1 2021: 175 institutionsQ2 2021: 205 institutionsQ3 2021: 181 institutionsQ4 2021: 187 institutionsQ1 2022: 212 institutionsQ2 2022: 212 institutionsQ3 2022: 250 institutionsQ4 2022: 244 institutionsQ1 2023: 282 institutionsQ2 2023: 317 institutionsQ3 2023: 256 institutionsQ4 2023: 284 institutionsQ1 2024: 302 institutionsQ2 2024: 263 institutionsQ3 2024: 265 institutionsQ4 2024: 260 institutionsQ1 2025: 255 institutionsQ2 2025: 247 institutionsQ3 2025: 273 institutionsQ4 2025: 280 institutionsQ1 2026: 324 institutionsQ2 2026: 1 institution
Value heldQ1 2022: $4.62B
Q1 2021: $2.80BQ2 2021: $4.08BQ3 2021: $2.29BQ4 2021: $3.83BQ1 2022: $4.62BQ2 2022: $4.15BQ3 2022: $6.66BQ4 2022: $5.20BQ1 2023: $7.28BQ2 2023: $9.71BQ3 2023: $4.34BQ4 2023: $6.82BQ1 2024: $6.65BQ2 2024: $4.43BQ3 2024: $3.41BQ4 2024: $4.04BQ1 2025: $2.80BQ2 2025: $2.28BQ3 2025: $2.77BQ4 2025: $3.17BQ1 2026: $5.56BQ2 2026: $10.2K
Institutions holding APLS and their total value by quarter
QuarterHoldersValue
Q2 20261$10.2K
Q1 2026324$5.56B
Q4 2025280$3.17B
Q3 2025273$2.77B
Q2 2025247$2.28B
Q1 2025255$2.80B
Q4 2024260$4.04B
Q3 2024265$3.41B
Q2 2024263$4.43B
Q1 2024302$6.65B
Q4 2023284$6.82B
Q3 2023256$4.34B
Q2 2023317$9.71B
Q1 2023282$7.28B
Q4 2022244$5.20B
Q3 2022250$6.66B
Q2 2022212$4.15B
Q1 2022212$4.62B
Q4 2021187$3.83B
Q3 2021181$2.29B
Q2 2021205$4.08B
Q1 2021175$2.80B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Apellis Pharmaceuticals, Inc.; share changes are against Q4 2021.

Institutions holding APLS in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
D. E. Shaw & Co., Inc.33,034$1.68M0.00%−4,856−12.8%Reduced
Graham Capital Management, L.P.35,030$1.78M0.08%+35,030New
Erste Asset Management GmbH37,000$1.83M0.03%00.0%Unchanged
HighVista Strategies LLC36,893$1.88M1.19%+36,893New
Skandinaviska Enskilda Banken AB (publ)37,054$1.88M0.01%+37,054New
American International Group, Inc.38,816$1.97M0.01%+828+2.2%Added
Integral Health Asset Management, LLC39,769$2.02M0.53%−80,231−66.9%Reduced
Ensign Peak Advisors, Inc40,180$2.04M0.00%−45,409−53.1%Reduced
J. Goldman & Co LP40,377$2.05M0.15%−7,636−15.9%Reduced
Employees Retirement System of Texas41,000$2.08M0.02%+41,000New
MetLife Investment Management41,293$2.10M0.01%+16,567+67.0%Added
Wells Fargo & Company41,419$2.10M0.00%−22,506−35.2%Reduced
Neuberger Berman Group LLC41,906$2.13M0.00%−59,217−58.6%Reduced
Guggenheim Capital LLC43,099$2.19M0.01%−5,152−10.7%Reduced
Russell Investments Group, Ltd.47,749$2.42M0.00%−60,202−55.8%Reduced
Polar Asset Management Partners Inc.48,200$2.45M0.03%−38,400−44.3%Reduced
Tudor Investment Corp Et Al48,840$2.48M0.06%+48,840New
Lisanti Capital Growth, LLC50,040$2.54M0.29%−53,385−51.6%Reduced
RTW Investments, LP51,194$2.60M0.05%−1,939,210−97.4%Reduced
Barclays PLC52,604$2.67M0.00%−92,644−63.8%Reduced
Verition Fund Management LLC52,899$2.69M0.05%−31,594−37.4%Reduced
Baird Financial Group, Inc.54,266$2.76M0.01%+1,191+2.2%Added
Group One Trading, L.P.55,546$2.82M0.06%+19,525+54.2%Added
EFG Asset Management (North America) Corp.56,550$2.87M0.43%−505−0.9%Reduced
The PNC Financial Services Group, Inc.57,699$2.93M0.00%+44,751+345.6%Added
First Trust Advisors LP57,809$2.94M0.00%+57,809New
State of New Jersey Common Pension Fund D59,226$3.01M0.01%−4,708−7.4%Reduced
Millennium Management LLC60,505$3.07M0.00%−251,497−80.6%Reduced
Nicholas Investment Partners, LP62,000$3.15M0.22%+62,000New
Man Group plc63,852$3.24M0.01%+63,852New
Fred Alger Management, LLC68,783$3.50M0.01%+68,783New
Sectoral Asset Management Inc69,500$3.53M0.63%+69,500New
Credit Suisse AG70,266$3.57M0.00%+7,234+11.5%Added
Legal & General Group Plc70,357$3.58M0.00%+1,190+1.7%Added
Private Advisor Group, LLC73,340$3.73M0.03%+98+0.1%Added
Voloridge Investment Management, LLC73,426$3.73M0.02%−2,736−3.6%Reduced
Jane Street Group, LLC75,110$3.82M0.01%−25,601−25.4%Reduced
Susquehanna International Group, LLP75,635$3.84M0.01%+6,886+10.0%Added
New York State Common Retirement Fund77,691$3.95M0.00%+11,877+18.0%Added
Rhumbline Advisers77,764$3.95M0.01%+3,835+5.2%Added
Royal Bank of Canada89,782$4.56M0.00%−15,408−14.6%Reduced
DAFNA Capital Management LLC93,935$4.77M1.24%+93,935New
State of Wisconsin Investment Board95,700$4.86M0.01%00.0%Unchanged
Voya Investment Management LLC96,009$4.88M0.01%−7,867−7.6%Reduced
Manufacturers Life Insurance Company, The100,299$5.00M0.00%+64,350+179.0%Added
California State Teachers Retirement System98,930$5.03M0.01%−4,771−4.6%Reduced
Silverarc Capital Management, LLC105,368$5.35M2.91%+105,368New
Nomura Holdings Inc104,067$5.72M0.04%+90,576+671.4%Added
UBS Group AG114,649$5.83M0.00%+5,262+4.8%Added
Hennion & Walsh Asset Management, Inc.119,322$6.06M0.32%−17,438−12.8%Reduced
Rafferty Asset Management, LLC123,495$6.28M0.04%−2,415−1.9%Reduced
Pier Capital, LLC130,208$6.62M0.84%−91,693−41.3%Reduced
Invesco Ltd.133,183$6.77M0.00%+84,634+174.3%Added
Privium Fund Management B.V.137,616$6.99M1.58%+10,000+7.8%Added
Clough Capital Partners L P142,409$7.24M0.55%+10,660+8.1%Added
Teachers Retirement System of the State of Kentucky144,468$7.34M0.07%+5,537+4.0%Added
Sessa Capital IM, L.P.149,000$7.57M0.46%+149,000New
Granahan Investment Management Inc153,923$7.82M0.19%+70,322+84.1%Added
Bank of Montreal168,107$8.32M0.00%−11,574−6.4%Reduced
Ameriprise Financial Inc169,621$8.62M0.00%+2,933+1.8%Added
Alliancebernstein L.P.178,670$9.08M0.00%+98,670+123.3%Added
Swiss National Bank181,100$9.20M0.01%+12,200+7.2%Added
Banque Pictet & Cie SA189,223$9.61M0.07%+20,734+12.3%Added
Tekla Capital Management LLC195,820$9.95M0.35%00.0%Unchanged
Artal Group S.A.200,000$10.2M0.43%+200,000New
Avidity Partners Management LP210,000$10.7M0.24%+210,000New
Lombard Odier Asset Management (Switzerland) SA221,251$11.2M0.88%−202,425−47.8%Reduced
Maven Securities LTD221,400$11.2M2.33%+221,400New
TD Asset Management Inc247,686$12.6M0.01%+86,641+53.8%Added
Ghost Tree Capital, LLC250,000$12.7M6.29%−75,000−23.1%Reduced
Caas Capital Management LP250,000$12.7M2.24%+250,000New
Morgan Stanley253,389$12.9M0.00%+185,730+274.5%Added
Natixis268,100$13.6M0.05%+268,100New
Nuveen Asset Management, LLC263,645$13.7M0.00%+7,204+2.8%Added
Bank of New York Mellon Corp315,480$16.0M0.00%+17,287+5.8%Added
Adage Capital Partners GP, L.L.C.325,000$16.5M0.03%+325,000New
Prudential Financial Inc332,202$16.9M0.02%+151,932+84.3%Added
Rhenman & Partners Asset Management AB377,000$19.2M1.89%−53,000−12.3%Reduced
Bank of America Corp381,958$19.4M0.00%+107,052+38.9%Added
UBS Asset Management Americas Inc390,140$19.8M0.01%+16,466+4.4%Added
Citadel Advisors LLC429,252$21.8M0.03%−524,479−55.0%Reduced
Candriam Luxembourg S.C.A.466,095$23.7M0.16%−228,330−32.9%Reduced
Goldman Sachs Group Inc500,254$25.4M0.01%+2,172+0.4%Added
Assenagon Asset Management S.A.513,027$26.1M0.08%+445,745+662.5%Added
Deutsche Bank AG544,311$27.7M0.01%+205,558+60.7%Added
Acuta Capital Partners, LLC554,000$28.1M13.39%+19,000+3.6%Added
Fiduciary Trust Co564,826$28.7M0.51%−150.0%Reduced
Driehaus Capital Management LLC628,645$31.9M0.39%+365,748+139.1%Added
Charles Schwab Investment Management Inc655,308$33.3M0.01%+63,394+10.7%Added
Northern Trust Corp765,202$38.9M0.01%+21,335+2.9%Added
Norges Bank814,965$41.4M0.01%+174,798+27.3%Added
Pictet Asset Management SA897,956$45.6M0.05%+251,597+38.9%Added
Logos Global Management LP900,000$45.7M5.93%−100,000−10.0%Reduced
Marshall Wace, LLP915,163$46.5M0.10%+915,163New
Bellevue Group AG1,098,712$55.8M0.65%+448,121+68.9%Added
Cormorant Asset Management, LP1,125,000$57.2M4.39%+500,000+80.0%Added
JPMorgan Chase & Co1,266,238$64.3M0.01%−321,640−20.3%Reduced
Boxer Capital, LLC1,303,700$66.2M3.40%+1,303,700New
Macquarie Group Ltd1,321,558$67.1M0.06%+29,775+2.3%Added
Victory Capital Management Inc1,324,964$67.2M0.07%−241,013−15.4%Reduced