Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 852
- +55 vs. Q3 2025
- Shares held
- 132.8M
- +3.06M (+2.4%) vs. Q3 2025
- Total value
- $52.7B
- −$6.43B (−10.9%) vs. Q3 2025
- New holders
- 172
- 290 more added
- Sold out
- 117
- 291 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Louisiana State Employees Retirement System | 8,800 | $3.50M | 0.06% | +8,800 | New |
| Vestmark Advisory Solutions, Inc. | 8,778 | $3.49M | 0.05% | +7,693+709.0% | Added |
| Walleye Trading LLC | 8,657 | $3.44M | 0.06% | +7,062+442.8% | Added |
| Transamerica Financial Advisors, Inc. | 8,606 | $3.42M | 0.29% | +8,529+11,076.6% | Added |
| S&CO Inc | 8,200 | $3.26M | 0.20% | 00.0% | Unchanged |
| MetLife Investment Management | 8,187 | $3.26M | 0.02% | +195+2.4% | Added |
| Rockefeller Capital Management L.P. | 8,124 | $3.23M | 0.01% | +3,744+85.5% | Added |
| Advisory Services Network, LLC | 8,093 | $3.22M | 0.05% | +1,087+15.5% | Added |
| M&T Bank Corp | 7,966 | $3.17M | 0.01% | +1,164+17.1% | Added |
| St Germain D J Co Inc | 7,857 | $3.12M | 0.12% | −294−3.6% | Reduced |
| Kentucky Retirement Systems | 7,836 | $3.12M | 0.08% | 00.0% | Unchanged |
| Prudential PLC | 7,829 | $3.11M | 0.02% | +133+1.7% | Added |
| La Banque Postale Asset Management SA | 7,790 | $3.10M | 0.04% | −394−4.8% | Reduced |
| Bank of Nova Scotia | 7,749 | $3.08M | 0.00% | +1,805+30.4% | Added |
| Osmosis Investment Management UK Ltd | 7,707 | $3.06M | 0.08% | +7,707 | New |
| NewEdge Wealth, LLC | 7,530 | $2.99M | 0.03% | −463−5.8% | Reduced |
| Edgestream Partners, L.P. | 7,248 | $2.88M | 0.08% | +7,248 | New |
| J.P. Marvel Investment Advisors, LLC | 7,105 | $2.83M | 0.39% | 00.0% | Unchanged |
| Colony Group, LLC | 7,083 | $2.82M | 0.00% | +466+7.0% | Added |
| PKO Investment Management Joint-Stock Co | 6,800 | $2.70M | 0.22% | +6,000+750.0% | Added |
| Dark Forest Capital Management LP | 6,715 | $2.67M | 0.12% | −4,883−42.1% | Reduced |
| Gulf International Bank (UK) Ltd | 6,627 | $2.63M | 0.09% | +249+3.9% | Added |
| Sanctuary Advisors, LLC | 6,520 | $2.59M | 0.01% | +345+5.6% | Added |
| Janney Montgomery Scott LLC | 6,503 | $2.59M | 0.01% | +2,448+60.4% | Added |
| Maryland State Retirement & Pension System | 6,346 | $2.52M | 0.05% | +160+2.6% | Added |
| Hussman Strategic Advisors, Inc. | 6,300 | $2.51M | 0.61% | +6,300 | New |
| Plato Investment Management Ltd | 6,254 | $2.50M | 0.16% | +1,348+27.5% | Added |
| Dai-Ichi Life Insurance Company, Ltd | 6,255 | $2.49M | 0.06% | +800+14.7% | Added |
| Atria Investments LLC | 6,173 | $2.45M | 0.03% | +979+18.8% | Added |
| Pathstone Holdings, LLC | 6,139 | $2.44M | 0.01% | −158−2.5% | Reduced |
| Truist Financial Corp | 6,105 | $2.43M | 0.00% | −361−5.6% | Reduced |
| Ci Investments Inc. | 6,052 | $2.41M | 0.01% | −1,172−16.2% | Reduced |
| Kestra Investment Management, LLC | 6,014 | $2.39M | 0.06% | +6,014 | New |
| Bridgeway Capital Management, LLC | 5,990 | $2.38M | 0.05% | −40−0.7% | Reduced |
| Walleye Capital LLC | 5,968 | $2.37M | 0.01% | −16,377−73.3% | Reduced |
| Tower Research Capital LLC (TRC) | 5,841 | $2.32M | 0.06% | +4,304+280.0% | Added |
| Abn Amro Investment Solutions | 5,759 | $2.29M | 0.03% | +4,449+339.6% | Added |
| AG2R la Mondiale Gestion D'Actifs | 5,595 | $2.22M | 0.10% | −230−3.9% | Reduced |
| Diadema Partners LP | 5,341 | $2.12M | 1.26% | −4,659−46.6% | Reduced |
| Westpac Banking Corp | 5,311 | $2.11M | 0.13% | +3,956+292.0% | Added |
| Genus Capital Management Inc. | 5,255 | $2.09M | 0.24% | −3,005−36.4% | Reduced |
| B. Metzler seel. Sohn & Co. AG | 5,252 | $2.09M | 0.02% | +1,339+34.2% | Added |
| US Bancorp | 5,236 | $2.08M | 0.00% | −410−7.3% | Reduced |
| Vident Advisory, LLC | 5,155 | $2.05M | 0.02% | −82−1.6% | Reduced |
| Gateway Investment Advisers LLC | 5,141 | $2.04M | 0.02% | 00.0% | Unchanged |
| Perpetual Ltd | 5,039 | $2.00M | 0.03% | +5,039 | New |
| Tokio Marine Asset Management Co Ltd | 5,015 | $1.99M | 0.07% | +571+12.8% | Added |
| Susquehanna Portfolio Strategies, LLC | 5,005 | $1.99M | 0.03% | 00.0% | Unchanged |
| West Michigan Advisors, LLC | 4,999 | $1.99M | 0.46% | −397−7.4% | Reduced |
| Toroso Investments, LLC | 4,825 | $1.92M | 0.01% | −2,066−30.0% | Reduced |
| AustralianSuper Pty Ltd | 4,803 | $1.91M | 0.01% | −939−16.4% | Reduced |
| North Dakota State Investment Board | 4,789 | $1.90M | 0.07% | +4,789 | New |
| Ameritas Investment Partners, Inc. | 4,776 | $1.90M | 0.06% | +4,776 | New |
| Azzad Asset Management Inc | 4,591 | $1.83M | 0.18% | −29−0.6% | Reduced |
| E. Ohman J:or Asset Management AB | 4,584 | $1.82M | 0.04% | −1,116−19.6% | Reduced |
| Burney Co | 4,582 | $1.82M | 0.06% | −301−6.2% | Reduced |
| Omers Administration Corp | 4,517 | $1.80M | 0.01% | 00.0% | Unchanged |
| Merit Financial Group, LLC | 4,511 | $1.79M | 0.01% | +279+6.6% | Added |
| Norinchukin Bank, The | 4,487 | $1.78M | 0.02% | +4,487 | New |
| Brevan Howard Capital Management LP | 4,437 | $1.76M | 0.03% | −1,733−28.1% | Reduced |
| Brinker Capital Investments, LLC | 4,405 | $1.75M | 0.01% | −993−18.4% | Reduced |
| Envestnet Portfolio Solutions, Inc. | 4,345 | $1.73M | 0.01% | +3,018+227.4% | Added |
| Quantitative Investment Management, LLC | 4,331 | $1.72M | 0.17% | +4,331 | New |
| Advisors Asset Management, Inc. | 4,303 | $1.71M | 0.03% | −219−4.8% | Reduced |
| NLB Skladi, upravljanje premozenja, d.o.o. | 4,300 | $1.71M | 0.08% | +4,300 | New |
| Hunting Hill Global Capital, LLC | 4,259 | $1.69M | 1.68% | +4,259 | New |
| Howland Capital Management LLC | 4,243 | $1.69M | 0.06% | 00.0% | Unchanged |
| Integrated Wealth Concepts LLC | 4,240 | $1.69M | 0.02% | −396−8.5% | Reduced |
| Sequoia Financial Advisors, LLC | 4,212 | $1.67M | 0.01% | −94−2.2% | Reduced |
| Metis Global Partners, LLC | 4,185 | $1.66M | 0.04% | −126−2.9% | Reduced |
| Pallas Capital Advisors LLC | 4,109 | $1.63M | 0.05% | −316−7.1% | Reduced |
| Buckingham Strategic Partners | 4,095 | $1.63M | 0.02% | −1,032−20.1% | Reduced |
| Comerica Bank | 4,040 | $1.61M | 0.01% | −7,750−65.7% | Reduced |
| Gilbert & Cook, Inc. | 4,018 | $1.60M | 0.20% | −1,490−27.1% | Reduced |
| Verition Fund Management LLC | 4,005 | $1.59M | 0.01% | −13,028−76.5% | Reduced |
| Atlantic Trust, LLC | 3,966 | $1.58M | 0.25% | −28−0.7% | Reduced |
| 683 Capital Management, LLC | 3,782 | $1.50M | 0.13% | +3,782 | New |
| Ambassador Advisors, LLC | 3,774 | $1.50M | 0.22% | +3,774 | New |
| Howard Capital Management Inc. | 3,680 | $1.46M | 0.02% | +2,826+330.9% | Added |
| Twin Tree Management, LP | 3,641 | $1.45M | 0.15% | −12,364−77.3% | Reduced |
| Brandywine Managers, LLC | 3,618 | $1.44M | 0.71% | −100−2.7% | Reduced |
| Callan Family Office, LLC | 3,614 | $1.44M | 0.03% | +858+31.1% | Added |
| Sterling Capital Management LLC | 3,557 | $1.41M | 0.02% | +730+25.8% | Added |
| Vestcor Inc | 3,533 | $1.41M | 0.04% | +1,006+39.8% | Added |
| Summit Trail Advisors, LLC | 3,514 | $1.40M | 0.02% | +79+2.3% | Added |
| Laird Norton Trust Company, LLC | 3,501 | $1.39M | 0.03% | +3,501 | New |
| Bamco Inc | 3,500 | $1.39M | 0.00% | 00.0% | Unchanged |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 3,500 | $1.39M | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 3,498 | $1.39M | 0.00% | −1,922−35.5% | Reduced |
| FORA Capital, LLC | 3,466 | $1.38M | 0.17% | +747+27.5% | Added |
| SummitTX Capital, L.P. | 3,465 | $1.38M | 0.04% | −4,060−54.0% | Reduced |
| J. Goldman & Co LP | 3,368 | $1.34M | 0.05% | +3,368 | New |
| Spectrum Planning & Advisory Services Inc. | 3,350 | $1.33M | 0.69% | 00.0% | Unchanged |
| Keybank National Association | 3,335 | $1.33M | 0.00% | −725−17.9% | Reduced |
| SBI Okasan Asset Management Co.Ltd. | 3,290 | $1.31M | 0.07% | +3,290 | New |
| Kentucky Retirement Systems Insurance Trust Fund | 3,285 | $1.31M | 0.08% | 00.0% | Unchanged |
| Values First Advisors, Inc. | 3,226 | $1.28M | 0.67% | −656−16.9% | Reduced |
| Ethic Inc. | 3,218 | $1.28M | 0.02% | +1,034+47.3% | Added |
| Kennedy Capital Management, Inc. | 3,215 | $1.28M | 0.03% | −5−0.2% | Reduced |
| Sumitomo Life Insurance Co | 3,194 | $1.27M | 0.03% | +27+0.9% | Added |