Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 594
- +35 vs. Q3 2024
- Shares held
- 127.8M
- +4.29M (+3.5%) vs. Q3 2024
- Total value
- $30.1B
- −$3.90B (−11.5%) vs. Q3 2024
- New holders
- 98
- 239 more added
- Sold out
- 63
- 180 more reduced
10 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital World Investors | 16,600,525 | $3.91B | 0.59% | +92,101+0.6% | Added |
| FMR LLC | 13,485,903 | $3.17B | 0.19% | −1,186,369−8.1% | Reduced |
| Vanguard Group Inc | 12,733,399 | $3.00B | 0.05% | +98,303+0.8% | Added |
| BlackRock, Inc. | 9,885,257 | $2.33B | 0.05% | +177,839+1.8% | Added |
| Capital Research Global Investors | 6,968,513 | $1.64B | 0.34% | +1,724,610+32.9% | Added |
| Regeneron Pharmaceuticals, Inc. | 4,444,445 | $1.05B | 95.54% | +4,444,445 | New |
| T. Rowe Price Investment Management, Inc. | 4,384,449 | $1.03B | 0.64% | +1,245,195+39.7% | Added |
| Wellington Management Group LLP | 4,196,623 | $987.5M | 0.18% | −756,724−15.3% | Reduced |
| Baillie Gifford & Co | 4,040,259 | $950.7M | 0.73% | −846,741−17.3% | Reduced |
| Dodge & Cox | 3,540,262 | $833.1M | 0.48% | −82,273−2.3% | Reduced |
| State Street Corp | 3,422,877 | $805.5M | 0.03% | −45,438−1.3% | Reduced |
| Price T Rowe Associates Inc | 3,319,385 | $781.1M | 0.09% | −132,448−3.8% | Reduced |
| Norges Bank | 2,456,082 | $577.9M | 0.08% | +80,547+3.4% | Added |
| JPMorgan Chase & Co | 2,250,060 | $529.5M | 0.04% | +87,116+4.0% | Added |
| Geode Capital Management, LLC | 2,206,800 | $518.4M | 0.04% | +59,597+2.8% | Added |
| American Century Companies Inc | 1,604,024 | $377.4M | 0.22% | +11,291+0.7% | Added |
| Orbis Allan Gray Ltd | 1,472,802 | $346.6M | 1.86% | +204,690+16.1% | Added |
| Capital International Investors | 1,418,602 | $333.8M | 0.06% | −2,552,261−64.3% | Reduced |
| Winslow Capital Management, LLC | 1,020,567 | $240.1M | 0.85% | +58,960+6.1% | Added |
| Northern Trust Corp | 878,860 | $206.8M | 0.03% | +143,941+19.6% | Added |
| Legal & General Group Plc | 828,917 | $195.1M | 0.05% | +37,188+4.7% | Added |
| AQR Capital Management LLC | 813,356 | $191.4M | 0.25% | +307,702+60.9% | Added |
| Bellevue Group AG | 770,268 | $181.3M | 3.49% | −38,827−4.8% | Reduced |
| Morgan Stanley | 727,224 | $171.1M | 0.01% | +108,661+17.6% | Added |
| UBS Asset Management Americas Inc | 710,598 | $167.2M | 0.04% | +4,367+0.6% | Added |
| Invesco Ltd. | 558,490 | $131.4M | 0.02% | −137,378−19.7% | Reduced |
| Deutsche Bank AG | 556,579 | $131.0M | 0.05% | +17,308+3.2% | Added |
| Charles Schwab Investment Management Inc | 513,962 | $120.9M | 0.02% | +26,614+5.5% | Added |
| Amundi | 496,301 | $119.4M | 0.04% | −97,019−16.4% | Reduced |
| TD Asset Management Inc | 504,038 | $118.6M | 0.10% | +15,755+3.2% | Added |
| Loomis Sayles & Co L P | 503,045 | $118.4M | 0.15% | −22,258−4.2% | Reduced |
| Qube Research & Technologies Ltd | 485,260 | $114.2M | 0.19% | +333,098+218.9% | Added |
| Bank of New York Mellon Corp | 479,203 | $112.8M | 0.02% | +4,764+1.0% | Added |
| Nuveen Asset Management, LLC | 448,881 | $105.6M | 0.03% | +7,789+1.8% | Added |
| Pictet Asset Management Holding SA | 430,612 | $101.3M | 0.11% | −234,110−35.2% | Reduced |
| Bank of America Corp | 418,552 | $98.5M | 0.01% | −132,220−24.0% | Reduced |
| OrbiMed Advisors LLC | 415,600 | $97.8M | 2.03% | +165,300+66.0% | Added |
| Franklin Resources Inc | 414,139 | $97.5M | 0.03% | +31,166+8.1% | Added |
| Marshall Wace, LLP | 378,649 | $89.1M | 0.11% | +315,182+496.6% | Added |
| Gilder Gagnon Howe & Co LLC | 365,463 | $86.0M | 0.93% | −18,530−4.8% | Reduced |
| D. E. Shaw & Co., Inc. | 363,085 | $85.4M | 0.09% | +30,780+9.3% | Added |
| Swiss National Bank | 362,600 | $85.3M | 0.06% | −12,800−3.4% | Reduced |
| Dimensional Fund Advisors LP | 333,661 | $78.5M | 0.02% | +32,272+10.7% | Added |
| Millennium Management LLC | 333,442 | $78.5M | 0.07% | +82,479+32.9% | Added |
| First Trust Advisors LP | 327,782 | $77.1M | 0.07% | +42,211+14.8% | Added |
| Royal Bank of Canada | 310,187 | $73.0M | 0.02% | −100,879−24.5% | Reduced |
| Polar Capital Holdings Plc | 310,000 | $72.9M | 0.41% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 306,455 | $72.1M | 0.01% | −49,645−13.9% | Reduced |
| UBS Group AG | 289,966 | $68.2M | 0.02% | +134,295+86.3% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 286,703 | $67.5M | 0.05% | +8,462+3.0% | Added |
| Candriam Luxembourg S.C.A. | 282,407 | $66.5M | 0.38% | −69,261−19.7% | Reduced |
| Royal London Asset Management Ltd | 281,509 | $66.2M | 0.16% | +1,759+0.6% | Added |
| CI Private Wealth, LLC | 278,566 | $65.5M | 0.11% | +810.0% | Added |
| Raymond James Financial Inc | 277,486 | $65.3M | 0.02% | +277,486 | New |
| Wells Fargo & Company | 276,962 | $65.2M | 0.02% | +10,465+3.9% | Added |
| SEI Investments Co | 266,000 | $62.6M | 0.08% | +28,093+11.8% | Added |
| Jennison Associates LLC | 259,913 | $61.2M | 0.04% | +259,913 | New |
| Rock Springs Capital Management LP | 256,200 | $60.3M | 2.30% | +6,200+2.5% | Added |
| Federated Hermes, Inc. | 249,591 | $58.7M | 0.13% | +80,668+47.8% | Added |
| Eventide Asset Management, LLC | 240,418 | $56.6M | 1.03% | +16,085+7.2% | Added |
| Westfield Capital Management Co LP | 216,126 | $50.9M | 0.22% | +216,126 | New |
| Janus Henderson Group PLC | 210,080 | $49.4M | 0.03% | −9,257−4.2% | Reduced |
| CIBC Private Wealth Group, LLC | 203,368 | $48.9M | 0.09% | −5,118−2.5% | Reduced |
| California Public Employees Retirement System | 204,132 | $48.0M | 0.03% | −7,649−3.6% | Reduced |
| California State Teachers Retirement System | 196,362 | $46.2M | 0.05% | +5,037+2.6% | Added |
| Standard Life Aberdeen plc | 190,841 | $45.2M | 0.08% | −9,228−4.6% | Reduced |
| Rhumbline Advisers | 179,578 | $42.3M | 0.04% | −1,850−1.0% | Reduced |
| Canada Pension Plan Investment Board | 174,021 | $40.9M | 0.04% | −170,837−49.5% | Reduced |
| Jane Street Group, LLC | 160,637 | $37.8M | 0.06% | +24,356+17.9% | Added |
| National Pension Service | 159,511 | $37.5M | 0.04% | −36,876−18.8% | Reduced |
| Worldquant Millennium Advisors LLC | 150,191 | $35.3M | 0.23% | +91,671+156.6% | Added |
| Deerfield Management Company, L.P. (Series C) | 145,191 | $34.2M | 0.65% | +191+0.1% | Added |
| Palo Alto Investors LP | 140,681 | $33.1M | 5.13% | 00.0% | Unchanged |
| Casdin Capital, LLC | 140,000 | $32.9M | 2.20% | −30,000−17.6% | Reduced |
| Antipodes Partners Ltd | 133,759 | $31.5M | 1.09% | −5,616−4.0% | Reduced |
| Ameriprise Financial Inc | 128,073 | $30.1M | 0.01% | −9,765−7.1% | Reduced |
| Squarepoint Ops LLC | 127,697 | $30.0M | 0.08% | +84,996+199.0% | Added |
| Schonfeld Strategic Advisors LLC | 127,000 | $29.9M | 0.19% | +99,133+355.7% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 125,491 | $29.6M | 0.13% | −24,628−16.4% | Reduced |
| State Board of Administration of Florida Retirement System | 125,240 | $29.5M | 0.06% | −4,177−3.2% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 124,360 | $29.3M | 0.06% | +124,360 | New |
| Mitsubishi UFJ Trust & Banking Corp | 116,686 | $27.5M | 0.06% | −3,646−3.0% | Reduced |
| HighTower Advisors, LLC | 115,380 | $27.2M | 0.04% | −410−0.4% | Reduced |
| Capital International Sarl | 115,142 | $27.1M | 0.63% | −19,931−14.8% | Reduced |
| DekaBank Deutsche Girozentrale | 113,193 | $26.5M | 0.05% | 00.0% | Unchanged |
| Sofinnova Investments, Inc. | 110,157 | $25.9M | 1.90% | +110,157 | New |
| Neuberger Berman Group LLC | 109,708 | $25.8M | 0.02% | +3,511+3.3% | Added |
| Manufacturers Life Insurance Company, The | 109,102 | $25.7M | 0.02% | −82,280−43.0% | Reduced |
| Allianz Asset Management GmbH | 108,871 | $25.6M | 0.04% | +82,065+306.1% | Added |
| Two Sigma Investments, LP | 107,117 | $25.2M | 0.06% | +87,969+459.4% | Added |
| Capital International Inc | 105,085 | $24.7M | 0.29% | −20,136−16.1% | Reduced |
| Frontier Capital Management Co LLC | 104,718 | $24.6M | 0.23% | −6,513−5.9% | Reduced |
| Barclays PLC | 103,847 | $24.4M | 0.01% | −1,338−1.3% | Reduced |
| Robeco Institutional Asset Management B.V. | 99,994 | $23.5M | 0.04% | +26,426+35.9% | Added |
| AXA S.A. | 95,306 | $22.4M | 0.07% | −15,910−14.3% | Reduced |
| Voya Investment Management LLC | 95,086 | $22.4M | 0.02% | −13,623−12.5% | Reduced |
| Los Angeles Capital Management LLC | 94,822 | $22.3M | 0.09% | −42,195−30.8% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 94,698 | $22.2M | 0.02% | +9,393+11.0% | Added |
| Korea Investment CORP | 93,603 | $22.0M | 0.05% | −14,290−13.2% | Reduced |
| Adage Capital Partners GP, L.L.C. | 93,056 | $21.9M | 0.04% | −22,944−19.8% | Reduced |