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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
653
+35 vs. Q1 2025
Shares held
132.1M
+2.77M (+2.1%) vs. Q1 2025
Total value
$43.1B
+$8.27B (+23.8%) vs. Q1 2025
New holders
98
262 more added
Sold out
63
214 more reduced

7 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 653 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ2 2025: $43.1B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding ALNY in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Capital World Investors16,805,007$5.48B0.80%+55,384+0.3%Added
FMR LLC15,806,521$5.15B0.29%+496,661+3.2%Added
Vanguard Group Inc13,297,139$4.34B0.07%+240,534+1.8%Added
BlackRock, Inc.9,980,163$3.25B0.06%+420,781+4.4%Added
Capital Research Global Investors7,191,656$2.35B0.47%+36,928+0.5%Added
Regeneron Pharmaceuticals, Inc.4,444,445$1.45B97.60%00.0%Unchanged
T. Rowe Price Investment Management, Inc.4,281,279$1.40B0.88%−136,866−3.1%Reduced
Dodge & Cox3,197,096$1.04B0.59%−154,666−4.6%Reduced
State Street Corp3,173,105$1.03B0.04%−193,478−5.7%Reduced
Price T Rowe Associates Inc3,145,006$1.03B0.12%−360,162−10.3%Reduced
Baillie Gifford & Co3,031,891$988.7M0.74%−625,716−17.1%Reduced
Geode Capital Management, LLC2,398,770$779.9M0.05%+75,936+3.3%Added
Orbis Allan Gray Ltd2,121,412$691.8M3.36%+486,489+29.8%Added
Wellington Management Group LLP2,075,752$676.9M0.12%−535,234−20.5%Reduced
JPMorgan Chase & Co2,062,008$672.4M0.05%−156,864−7.1%Reduced
Norges Bank2,032,680$662.8M0.08%−103,344−4.8%Reduced
American Century Companies Inc1,793,846$585.0M0.32%+33,411+1.9%Added
Invesco Ltd.1,341,694$437.5M0.07%+427,902+46.8%Added
Bank of America Corp1,257,328$410.0M0.03%+192,755+18.1%Added
Winslow Capital Management, LLC1,177,439$384.0M1.28%−9,739−0.8%Reduced
UBS Asset Management Americas Inc958,336$312.5M0.06%+222,225+30.2%Added
Legal & General Group Plc872,771$284.6M0.07%−8,340−0.9%Reduced
Northern Trust Corp831,777$271.2M0.04%−33,243−3.8%Reduced
Nuveen, LLC774,969$252.7M0.07%−108,405−12.3%Reduced
Morgan Stanley770,968$251.4M0.02%+129,203+20.1%Added
Bellevue Group AG676,367$220.6M4.86%−91,780−11.9%Reduced
Deutsche Bank AG649,284$211.7M0.08%+72,291+12.5%Added
Woodline Partners LP623,115$203.2M1.07%+466,651+298.2%Added
Franklin Resources Inc601,331$196.1M0.05%+143,017+31.2%Added
Citadel Advisors LLC601,199$196.0M0.17%+596,963+14,092.6%Added
Macquarie Group Ltd600,111$195.7M0.24%+527,519+726.7%Added
Holocene Advisors, LP596,816$194.6M0.48%+596,816New
Charles Schwab Investment Management Inc571,747$186.4M0.03%+25,105+4.6%Added
Clearbridge Investments, LLC557,099$181.7M0.15%+549,322+7,063.4%Added
Goldman Sachs Group Inc545,316$177.8M0.03%+121,949+28.8%Added
UBS Group AG543,486$177.2M0.04%+264,848+95.1%Added
Loomis Sayles & Co L P487,328$158.9M0.20%−10,156−2.0%Reduced
Pictet Asset Management Holding SA464,606$151.2M0.15%−16,361−3.4%Reduced
TD Asset Management Inc441,177$143.9M0.12%−45,407−9.3%Reduced
Royal Bank of Canada430,835$140.5M0.03%+93,604+27.8%Added
Bank of New York Mellon Corp429,769$140.1M0.03%−45,063−9.5%Reduced
Amundi394,179$130.0M0.04%−60,816−13.4%Reduced
Swiss National Bank393,800$128.4M0.08%+29,600+8.1%Added
Jennison Associates LLC350,070$114.2M0.07%+40,851+13.2%Added
Two Sigma Investments, LP343,305$111.9M0.20%+145,890+73.9%Added
OrbiMed Advisors LLC341,900$111.5M2.80%−4,200−1.2%Reduced
Gilder Gagnon Howe & Co LLC337,088$109.9M1.17%−8,487−2.5%Reduced
Federated Hermes, Inc.323,842$105.6M0.20%+59,669+22.6%Added
Wells Fargo & Company321,824$104.9M0.02%+21,744+7.2%Added
SEI Investments Co308,619$100.6M0.12%+31,250+11.3%Added
Allspring Global Investments Holdings, LLC312,216$100.6M0.17%+41,292+15.2%Added
Dimensional Fund Advisors LP305,563$99.6M0.02%−4,256−1.4%Reduced
Sumitomo Mitsui Trust Holdings, Inc.293,542$95.7M0.06%+2,066+0.7%Added
Raymond James Financial Inc270,450$88.2M0.03%+1,480+0.6%Added
Two Sigma Advisers, LP266,100$86.8M0.18%−9,700−3.5%Reduced
Royal London Asset Management Ltd259,071$84.5M0.19%−27,872−9.7%Reduced
First Trust Advisors LP251,817$82.1M0.07%+71,357+39.5%Added
Citigroup Inc248,238$80.9M0.06%+53,504+27.5%Added
Marshall Wace, LLP238,573$77.8M0.09%−30,359−11.3%Reduced
Candriam Luxembourg S.C.A.238,084$77.6M0.45%−11,835−4.7%Reduced
Polar Capital Holdings Plc237,500$77.4M0.41%−42,500−15.2%Reduced
1832 Asset Management L.P.223,345$72.8M0.13%+79,300+55.1%Added
CIBC Private Wealth Group, LLC218,329$71.2M0.13%+12,818+6.2%Added
Standard Life Aberdeen plc218,624$70.4M0.12%+3,239+1.5%Added
California Public Employees Retirement System211,581$69.0M0.04%+10,100+5.0%Added
Voya Investment Management LLC211,045$68.8M0.07%+119,901+131.6%Added
Susquehanna International Group, LLP208,262$67.9M0.10%+137,797+195.6%Added
Allianz Asset Management GmbH205,993$67.2M0.09%−12,510−5.7%Reduced
Point72 Asset Management, L.P.201,396$65.7M0.16%−99,239−33.0%Reduced
Rhumbline Advisers200,485$65.4M0.06%+19,022+10.5%Added
California State Teachers Retirement System199,316$65.0M0.07%+1,873+0.9%Added
Ameriprise Financial Inc193,649$63.1M0.02%+84,513+77.4%Added
KBC Group NV193,550$63.1M0.17%+174,238+902.2%Added
AQR Capital Management LLC188,249$61.3M0.05%−640,095−77.3%Reduced
Westfield Capital Management Co LP186,905$60.9M0.26%−5,267−2.7%Reduced
National Pension Service175,046$57.1M0.05%+1,387+0.8%Added
SCS Capital Management LLC170,662$55.7M0.62%−415−0.2%Reduced
Arrowstreet Capital, Limited Partnership169,700$55.3M0.04%+165,645+4,085.0%Added
Victory Capital Management Inc156,294$51.0M0.03%+118,645+315.1%Added
Handelsbanken Fonder AB155,362$50.7M0.18%+38,679+33.1%Added
Janus Henderson Group PLC150,421$49.0M0.02%−31,228−17.2%Reduced
FIL Ltd147,937$48.2M0.04%+30,075+25.5%Added
Deerfield Management Company, L.P. (Series C)145,000$47.3M0.86%00.0%Unchanged
BNP Paribas Arbitrage, SA128,634$41.9M0.03%+86,059+202.1%Added
Capital International Sarl128,286$41.8M0.80%+7,126+5.9%Added
State Board of Administration of Florida Retirement System127,050$41.4M0.07%+1,810+1.4%Added
Eventide Asset Management, LLC125,902$41.1M0.72%−40,548−24.4%Reduced
Antipodes Partners Ltd122,804$40.0M1.24%−36,750−23.0%Reduced
Worldquant Millennium Advisors LLC117,373$38.3M0.19%−73,732−38.6%Reduced
Balyasny Asset Management LLC115,275$37.6M0.09%+102,159+778.9%Added
Universal- Beteiligungs- und Servicegesellschaft mbH114,366$37.3M0.07%−3,354−2.8%Reduced
DekaBank Deutsche Girozentrale113,193$36.5M0.07%+151+0.1%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.111,785$36.5M0.03%+5,906+5.6%Added
Korea Investment CORP110,855$36.1M0.08%+5,096+4.8%Added
HighTower Advisors, LLC109,265$35.6M0.04%−4,592−4.0%Reduced
D. E. Shaw & Co., Inc.108,276$35.3M0.04%−181,586−62.6%Reduced
Soleus Capital Management, L.P.106,750$34.8M2.40%+106,750New
Frontier Capital Management Co LLC103,003$33.6M0.31%+583+0.6%Added
Ensign Peak Advisors, Inc100,209$32.7M0.06%+19,730+24.5%Added
Rock Springs Capital Management LP100,000$32.6M2.03%−43,250−30.2%Reduced