Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 823
- +178 vs. Q2 2025
- Shares held
- 129.9M
- −193.8K (−0.1%) vs. Q2 2025
- Total value
- $59.2B
- +$16.8B (+39.6%) vs. Q2 2025
- New holders
- 225
- 283 more added
- Sold out
- 47
- 223 more reduced
8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 16,767,625 | $7.65B | 0.40% | +961,104+6.1% | Added |
| Capital World Investors | 16,434,253 | $7.49B | 1.02% | −370,754−2.2% | Reduced |
| Vanguard Group Inc | 13,565,452 | $6.19B | 0.09% | +268,313+2.0% | Added |
| BlackRock, Inc. | 9,903,601 | $4.52B | 0.08% | −76,562−0.8% | Reduced |
| Capital Research Global Investors | 7,222,840 | $3.29B | 0.62% | +31,184+0.4% | Added |
| JPMorgan Chase & Co | 4,543,770 | $2.07B | 0.13% | +2,481,762+120.4% | Added |
| State Street Corp | 3,081,475 | $1.41B | 0.05% | −91,630−2.9% | Reduced |
| Baillie Gifford & Co | 2,789,356 | $1.27B | 0.94% | −242,535−8.0% | Reduced |
| Geode Capital Management, LLC | 2,499,242 | $1.14B | 0.07% | +100,472+4.2% | Added |
| Dodge & Cox | 2,321,230 | $1.06B | 0.57% | −875,866−27.4% | Reduced |
| T. Rowe Price Investment Management, Inc. | 2,173,984 | $991.3M | 0.61% | −2,107,295−49.2% | Reduced |
| Orbis Allan Gray Ltd | 1,950,962 | $889.6M | 3.82% | −170,450−8.0% | Reduced |
| Wellington Management Group LLP | 1,826,321 | $832.8M | 0.15% | −249,431−12.0% | Reduced |
| Price T Rowe Associates Inc | 1,800,294 | $820.9M | 0.09% | −1,344,712−42.8% | Reduced |
| American Century Companies Inc | 1,641,441 | $748.5M | 0.38% | −152,405−8.5% | Reduced |
| Bank of America Corp | 1,498,491 | $683.3M | 0.05% | +241,163+19.2% | Added |
| Invesco Ltd. | 1,481,842 | $675.7M | 0.11% | +140,148+10.4% | Added |
| Regeneron Pharmaceuticals, Inc. | 1,392,303 | $634.9M | 90.64% | −3,052,142−68.7% | Reduced |
| Arrowstreet Capital, Limited Partnership | 1,355,609 | $618.2M | 0.39% | +1,185,909+698.8% | Added |
| Jane Street Group, LLC | 958,750 | $437.2M | 0.51% | +935,894+4,094.7% | Added |
| Two Sigma Advisers, LP | 892,500 | $407.0M | 0.81% | +626,400+235.4% | Added |
| Legal & General Group Plc | 887,780 | $404.8M | 0.09% | +15,009+1.7% | Added |
| Northern Trust Corp | 833,151 | $379.9M | 0.05% | +1,374+0.2% | Added |
| Qube Research & Technologies Ltd | 811,278 | $369.9M | 0.52% | +811,278 | New |
| AQR Capital Management LLC | 744,008 | $336.0M | 0.22% | +555,759+295.2% | Added |
| Morgan Stanley | 726,061 | $331.1M | 0.02% | −44,907−5.8% | Reduced |
| Franklin Resources Inc | 714,012 | $325.6M | 0.08% | +112,681+18.7% | Added |
| UBS Asset Management Americas Inc | 708,564 | $323.1M | 0.07% | −249,772−26.1% | Reduced |
| Macquarie Group Ltd | 648,344 | $295.6M | 0.35% | +48,233+8.0% | Added |
| Clearbridge Investments, LLC | 622,435 | $283.8M | 0.21% | +65,336+11.7% | Added |
| Charles Schwab Investment Management Inc | 618,770 | $282.2M | 0.05% | +47,023+8.2% | Added |
| Deutsche Bank AG | 606,320 | $276.5M | 0.09% | −42,964−6.6% | Reduced |
| Two Sigma Investments, LP | 595,926 | $271.7M | 0.42% | +252,621+73.6% | Added |
| Nuveen, LLC | 587,821 | $268.0M | 0.07% | −187,148−24.1% | Reduced |
| Susquehanna International Group, LLP | 577,632 | $263.4M | 0.39% | +369,370+177.4% | Added |
| Federated Hermes, Inc. | 550,104 | $250.8M | 0.44% | +226,262+69.9% | Added |
| Millennium Management LLC | 549,931 | $250.8M | 0.20% | +459,486+508.0% | Added |
| Goldman Sachs Group Inc | 538,346 | $245.5M | 0.04% | −6,970−1.3% | Reduced |
| Marshall Wace, LLP | 508,371 | $231.8M | 0.25% | +269,798+113.1% | Added |
| Loomis Sayles & Co L P | 500,672 | $228.3M | 0.27% | +13,344+2.7% | Added |
| UBS Group AG | 488,204 | $222.6M | 0.04% | −55,282−10.2% | Reduced |
| 1832 Asset Management L.P. | 459,345 | $209.5M | 0.35% | +236,000+105.7% | Added |
| Bellevue Group AG | 446,524 | $203.6M | 4.23% | −229,843−34.0% | Reduced |
| Royal Bank of Canada | 436,758 | $199.2M | 0.04% | +5,923+1.4% | Added |
| Bank of New York Mellon Corp | 419,783 | $191.4M | 0.03% | −9,986−2.3% | Reduced |
| Jacobs Levy Equity Management, Inc | 410,342 | $187.1M | 0.74% | +392,668+2,221.7% | Added |
| Pictet Asset Management Holding SA | 387,546 | $176.0M | 0.17% | −77,060−16.6% | Reduced |
| Amundi | 384,272 | $173.7M | 0.06% | −9,907−2.5% | Reduced |
| Raymond James Financial Inc | 377,294 | $172.0M | 0.06% | +106,844+39.5% | Added |
| Swiss National Bank | 375,800 | $171.4M | 0.10% | −18,000−4.6% | Reduced |
| Voya Investment Management LLC | 373,356 | $170.3M | 0.17% | +162,311+76.9% | Added |
| Voloridge Investment Management, LLC | 356,806 | $162.7M | 0.55% | +349,104+4,532.6% | Added |
| Massachusetts Financial Services Co | 356,529 | $162.6M | 0.05% | +356,529 | New |
| Gilder Gagnon Howe & Co LLC | 329,321 | $150.2M | 1.53% | −7,767−2.3% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 314,452 | $143.4M | 0.08% | +20,910+7.1% | Added |
| Allspring Global Investments Holdings, LLC | 310,804 | $143.2M | 0.23% | −1,412−0.5% | Reduced |
| TD Asset Management Inc | 312,517 | $142.5M | 0.12% | −128,660−29.2% | Reduced |
| Jennison Associates LLC | 304,863 | $139.0M | 0.08% | −45,207−12.9% | Reduced |
| OrbiMed Advisors LLC | 301,600 | $137.5M | 3.30% | −40,300−11.8% | Reduced |
| HRT Financial LP | 291,449 | $132.9M | 0.49% | +273,562+1,529.4% | Added |
| Susquehanna Advisors Group, Inc. | 286,100 | $130.5M | 4.02% | +286,100 | New |
| Wells Fargo & Company | 280,568 | $127.9M | 0.03% | −41,256−12.8% | Reduced |
| KBC Group NV | 273,352 | $124.6M | 0.30% | +79,802+41.2% | Added |
| Royal London Asset Management Ltd | 257,313 | $117.3M | 0.25% | −1,758−0.7% | Reduced |
| Polar Capital Holdings Plc | 251,460 | $114.7M | 0.55% | +13,960+5.9% | Added |
| Dimensional Fund Advisors LP | 241,934 | $110.3M | 0.02% | −63,629−20.8% | Reduced |
| California Public Employees Retirement System | 229,641 | $104.7M | 0.06% | +18,060+8.5% | Added |
| Ameriprise Financial Inc | 225,879 | $103.0M | 0.02% | +32,230+16.6% | Added |
| Citadel Advisors LLC | 221,843 | $101.2M | 0.08% | −379,356−63.1% | Reduced |
| Worldquant Millennium Advisors LLC | 220,634 | $100.6M | 0.43% | +103,261+88.0% | Added |
| CIBC Private Wealth Group, LLC | 214,213 | $97.7M | 0.17% | −4,116−1.9% | Reduced |
| Candriam Luxembourg S.C.A. | 212,416 | $96.9M | 0.51% | −25,668−10.8% | Reduced |
| First Trust Advisors LP | 210,383 | $95.9M | 0.07% | −41,434−16.5% | Reduced |
| California State Teachers Retirement System | 203,778 | $92.9M | 0.10% | +4,462+2.2% | Added |
| D. E. Shaw & Co., Inc. | 199,417 | $90.9M | 0.07% | +91,141+84.2% | Added |
| Korea Investment CORP | 196,912 | $89.8M | 0.18% | +86,057+77.6% | Added |
| Rhumbline Advisers | 196,497 | $89.6M | 0.07% | −3,988−2.0% | Reduced |
| Russell Investments Group, Ltd. | 195,916 | $89.2M | 0.10% | +102,481+109.7% | Added |
| Victory Capital Management Inc | 180,349 | $82.2M | 0.05% | +24,055+15.4% | Added |
| National Pension Service | 177,238 | $80.8M | 0.06% | +2,192+1.3% | Added |
| Los Angeles Capital Management LLC | 159,394 | $72.7M | 0.25% | +91,995+136.5% | Added |
| Standard Life Aberdeen plc | 157,396 | $71.7M | 0.11% | −61,228−28.0% | Reduced |
| Handelsbanken Fonder AB | 155,369 | $70.8M | 0.23% | +70.0% | Added |
| BNP Paribas Arbitrage, SA | 153,039 | $69.8M | 0.05% | +24,405+19.0% | Added |
| SCS Capital Management LLC | 150,668 | $68.7M | 0.75% | −19,994−11.7% | Reduced |
| Squarepoint Ops LLC | 145,565 | $66.4M | 0.14% | +143,119+5,851.1% | Added |
| Canada Pension Plan Investment Board | 136,331 | $62.2M | 0.04% | +100,811+283.8% | Added |
| Janus Henderson Group PLC | 135,855 | $61.9M | 0.03% | −14,566−9.7% | Reduced |
| FIL Ltd | 135,484 | $61.8M | 0.05% | −12,453−8.4% | Reduced |
| Neuberger Berman Group LLC | 130,544 | $59.5M | 0.04% | +31,500+31.8% | Added |
| Capital International Sarl | 129,702 | $59.1M | 1.02% | +1,416+1.1% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 120,787 | $55.1M | 0.04% | +9,002+8.1% | Added |
| Envestnet Asset Management Inc | 118,964 | $54.2M | 0.02% | +23,168+24.2% | Added |
| Frontier Capital Management Co LLC | 118,878 | $54.2M | 0.49% | +15,875+15.4% | Added |
| Congress Asset Management Co | 118,800 | $54.2M | 0.36% | +118,800 | New |
| State Board of Administration of Florida Retirement System | 117,226 | $53.5M | 0.09% | −9,824−7.7% | Reduced |
| Robeco Institutional Asset Management B.V. | 113,074 | $51.6M | 0.07% | +16,706+17.3% | Added |
| HighTower Advisors, LLC | 110,624 | $50.4M | 0.06% | +1,359+1.2% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 110,552 | $50.4M | 0.08% | −3,814−3.3% | Reduced |
| DekaBank Deutsche Girozentrale | 113,193 | $50.3M | 0.08% | 00.0% | Unchanged |