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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
823
+178 vs. Q2 2025
Shares held
129.9M
−193.8K (−0.1%) vs. Q2 2025
Total value
$59.2B
+$16.8B (+39.6%) vs. Q2 2025
New holders
225
283 more added
Sold out
47
223 more reduced

8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 823 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ3 2025: $59.2B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.

Institutions holding ALNY in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Allianz Asset Management GmbH106,816$48.7M0.06%−99,177−48.1%Reduced
Aviva PLC103,206$47.1M0.09%+6,141+6.3%Added
Eventide Asset Management, LLC101,739$46.4M0.76%−24,163−19.2%Reduced
SEI Investments Co94,481$43.1M0.05%−214,138−69.4%Reduced
Barclays PLC94,408$43.1M0.02%+350+0.4%Added
Woodline Partners LP91,791$41.9M0.20%−531,324−85.3%Reduced
Great West Life Assurance Co93,092$41.6M0.06%+1,938+2.1%Added
Nomura Asset Management Co Ltd89,869$41.0M0.11%−1,505−1.6%Reduced
Westfield Capital Management Co LP87,908$40.1M0.17%−98,997−53.0%Reduced
Parkman Healthcare Partners LLC87,690$40.0M4.39%−4,648−5.0%Reduced
Aquatic Capital Management LLC84,059$38.3M0.71%+84,059New
Assenagon Asset Management S.A.80,381$36.7M0.05%+62,695+354.5%Added
Skandinaviska Enskilda Banken AB (publ)79,652$36.3M0.15%−5,236−6.2%Reduced
Capital International Ltd78,223$35.7M1.29%−4,577−5.5%Reduced
Jain Global LLC78,046$35.6M0.46%+61,316+366.5%Added
Mitsubishi UFJ Trust & Banking Corp77,461$35.3M0.08%−8,273−9.6%Reduced
Capital International Inc75,638$34.5M0.28%+3,807+5.3%Added
Rock Springs Capital Management LP74,250$33.9M1.98%−25,750−25.8%Reduced
HSBC Holdings PLC73,014$33.3M0.02%−8,734−10.7%Reduced
Storebrand Asset Management AS72,017$32.8M0.09%+27,696+62.5%Added
Man Group plc71,673$32.7M0.06%+63,564+783.9%Added
Asset Management One Co.,Ltd.69,610$31.7M0.09%+300+0.4%Added
State of Wisconsin Investment Board68,529$31.2M0.07%−9,577−12.3%Reduced
Deerfield Management Company, L.P. (Series C)67,935$31.0M0.47%−77,065−53.1%Reduced
Ensign Peak Advisors, Inc67,733$30.9M0.05%−32,476−32.4%Reduced
Manufacturers Life Insurance Company, The67,672$30.9M0.03%−19,168−22.1%Reduced
Lord, Abbett & Co. LLC67,220$30.7M0.09%+67,220New
New York State Common Retirement Fund64,424$29.4M0.04%+1,152+1.8%Added
Swedbank AB63,578$29.0M0.03%−737−1.1%Reduced
Panagora Asset Management Inc62,354$28.4M0.11%−30,145−32.6%Reduced
Ieq Capital, LLC62,177$28.4M0.09%+56,055+915.6%Added
AXA Investment Managers S.A.61,663$28.1M0.08%+61,663New
Driehaus Capital Management LLC61,379$28.0M0.20%−18,335−23.0%Reduced
Citigroup Inc60,866$27.8M0.02%−187,372−75.5%Reduced
Integral Health Asset Management, LLC60,000$27.4M1.99%+5,000+9.1%Added
Danske Bank A/S57,407$26.2M0.07%+2,400+4.4%Added
Treasurer of the State of North Carolina56,123$25.6M0.08%−2,181−3.7%Reduced
Casdin Capital, LLC55,000$25.1M2.09%−26,500−32.5%Reduced
Fiera Capital Corp53,804$24.5M0.08%+26,061+93.9%Added
Quadrature Capital Ltd48,920$22.3M0.26%+47,033+2,492.5%Added
KLP Kapitalforvaltning AS48,800$22.3M0.09%−300−0.6%Reduced
LPL Financial LLC48,480$22.1M0.01%+18,141+59.8%Added
State of New Jersey Common Pension Fund D45,532$20.8M0.08%+1,673+3.8%Added
Engineers Gate Manager LP43,849$20.0M0.23%+11,219+34.4%Added
Alliancebernstein L.P.43,776$20.0M0.01%−23,355−34.8%Reduced
Lansforsakringar Fondforvaltning AB (publ)42,404$19.3M0.10%+2,173+5.4%Added
Resona Asset Management Co.,Ltd.41,497$18.9M0.09%−2,203−5.0%Reduced
Van Eck Associates Corp41,133$18.8M0.02%−13,427−24.6%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)40,944$18.7M0.04%+10,193+33.1%Added
Groupama Asset Managment32,082$18.6M0.27%−16,303−33.7%Reduced
CI Private Wealth, LLC39,392$18.0M0.03%−2,760−6.5%Reduced
Bronte Capital Management Pty Ltd.34,974$17.8M1.61%+34,974New
Public Employees Retirement System of Ohio38,994$17.8M0.06%+242+0.6%Added
Arizona State Retirement System38,512$17.6M0.09%+584+1.5%Added
Investment Management Corp of Ontario37,958$17.3M0.26%+6,437+20.4%Added
Oddo BHF Asset Management SAS37,927$17.3M0.66%+1,987+5.5%Added
Parnassus Investments37,014$16.9M0.04%−398−1.1%Reduced
Jump Financial, LLC34,877$15.9M0.20%+17,485+100.5%Added
Artia Global Partners LP34,570$15.8M2.77%+13,600+64.9%Added
DnB Asset Management AS34,268$15.6M0.06%+6,805+24.8%Added
Rosenblum Silverman Sutton S F Inc34,002$15.5M3.54%−390−1.1%Reduced
Voleon Capital Management LP33,965$15.5M0.38%+32,609+2,404.8%Added
Bridgewater Associates, LP33,911$15.5M0.06%+33,911New
Teacher Retirement System of Texas33,642$15.3M0.06%−2,766−7.6%Reduced
AIA Group Ltd33,313$15.2M0.27%+3,081+10.2%Added
Teachers Retirement System of the State of Kentucky32,818$15.0M0.11%−400−1.2%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.32,369$14.8M0.04%+967+3.1%Added
Palo Alto Investors LP32,320$14.7M2.73%−43,215−57.2%Reduced
Antipodes Partners Ltd31,956$14.6M0.33%−90,848−74.0%Reduced
Rhenman & Partners Asset Management AB31,875$14.5M1.61%−19,322−37.7%Reduced
SG Americas Securities, LLC31,850$14.5M0.05%+31,850New
ExodusPoint Capital Management, LP30,823$14.1M0.20%+30,823New
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund30,215$13.8M0.12%+200+0.7%Added
Zurich Insurance Group Ltd29,988$13.7M0.10%−37,806−55.8%Reduced
CWM, LLC29,287$13.4M0.04%+23,775+431.3%Added
Polymer Capital Management (HK) LTD28,900$13.2M1.83%+31+0.1%Added
Gotham Asset Management, LLC28,135$12.8M0.06%+10,348+58.2%Added
STRS Ohio27,985$12.8M0.05%−2,155−7.1%Reduced
Forsta Ap-Fonden27,900$12.7M0.08%+1,500+5.7%Added
U.S. Capital Wealth Advisors, LLC27,544$12.6M0.34%−24,483−47.1%Reduced
Cerity Partners LLC27,429$12.5M0.02%+17,316+171.2%Added
Illinois Municipal Retirement Fund27,145$12.4M0.16%+1,099+4.2%Added
Brown Advisory Inc26,592$12.1M0.02%−2,879−9.8%Reduced
USS Investment Management Ltd26,366$12.0M0.06%00.0%Unchanged
Mariner, LLC26,332$12.0M0.02%+11,259+74.7%Added
Xponance, Inc.26,152$11.9M0.09%+1,135+4.5%Added
Erste Asset Management GmbH26,010$11.6M0.11%−3,800−12.7%Reduced
IFM Investors Pty Ltd26,041$11.6M0.10%+683+2.7%Added
Mediolanum International Funds Ltd25,451$11.4M0.12%+25,451New
Advisor Group Holdings, Inc.24,938$11.3M0.02%+21,151+558.5%Added
Kornitzer Capital Management Inc23,689$10.8M0.22%+525+2.3%Added
Eagle Health Investments LP23,686$10.8M2.84%−22,400−48.6%Reduced
Creative Planning22,862$10.4M0.01%+7,282+46.7%Added
China Universal Asset Management Co., Ltd.22,787$10.4M0.86%−5,030−18.1%Reduced
AMF Pensionsforsakring AB22,558$10.3M0.07%−9,979−30.7%Reduced
Walleye Capital LLC22,345$10.2M0.08%−16,370−42.3%Reduced
Banco Bilbao Vizcaya Argentaria, S.A.22,235$10.1M0.08%−16−0.1%Reduced
Atika Capital Management LLC22,206$10.1M0.86%−5,494−19.8%Reduced
Natixis Advisors, L.P.21,682$9.89M0.01%+11,573+114.5%Added
Swiss Life Asset Management Ltd21,521$9.81M0.05%−2,268−9.5%Reduced