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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
823
+178 vs. Q2 2025
Shares held
129.9M
−193.8K (−0.1%) vs. Q2 2025
Total value
$59.2B
+$16.8B (+39.6%) vs. Q2 2025
New holders
225
283 more added
Sold out
47
223 more reduced

8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 823 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ3 2025: $59.2B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.

Institutions holding ALNY in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Toronto Dominion Bank21,227$9.68M0.02%−2,404−10.2%Reduced
Ilmarinen Mutual Pension Insurance Co21,000$9.58M0.07%00.0%Unchanged
Andra AP-fonden20,700$9.44M0.12%+13,800+200.0%Added
Utah Retirement Systems20,599$9.39M0.09%−371−1.8%Reduced
Stifel Financial Corp20,295$9.25M0.01%+6,595+48.1%Added
Police & Firemen's Retirement System of New Jersey20,093$9.16M0.07%+1,130+6.0%Added
MML Investors Services, LLC19,678$8.97M0.02%+1,840+10.3%Added
Quantinno Capital Management LP19,265$8.79M0.02%+5,801+43.1%Added
Acadian Asset Management LLC19,083$8.70M0.02%+11,364+147.2%Added
British Columbia Investment Management Corp18,739$8.54M0.05%−1,732−8.5%Reduced
Elo Mutual Pension Insurance Co17,865$8.15M0.13%+3,738+26.5%Added
Caisse de Depot Et Placement du Quebec17,826$8.13M0.01%−2,218−11.1%Reduced
Silvant Capital Management LLC17,676$8.06M0.28%−1,671−8.6%Reduced
Entropy Technologies, LP17,181$7.83M0.59%+16,081+1,461.9%Added
Rafferty Asset Management, LLC17,151$7.82M0.03%−15,045−46.7%Reduced
Verition Fund Management LLC17,033$7.77M0.04%+11,330+198.7%Added
Capital Group Investment Management Pte. Ltd.16,863$7.69M1.29%−875−4.9%Reduced
Nissay Asset Management Corp16,575$7.56M0.04%+287+1.8%Added
Jefferies Financial Group Inc.16,542$7.54M0.07%+8,200+98.3%Added
EFG Asset Management (North America) Corp.16,335$7.44M0.96%−4,827−22.8%Reduced
Twin Tree Management, LP16,005$7.30M0.34%+16,005New
Quantessence Capital LLC15,874$7.24M2.29%+15,874New
Sumitomo Mitsui DS Asset Management Company, Ltd15,826$7.22M0.06%+1,018+6.9%Added
Daiwa Securities Group Inc.15,496$7.07M0.02%+2,555+19.7%Added
Mutual of America Capital Management LLC15,307$6.98M0.07%−639−4.0%Reduced
Soleus Capital Management, L.P.15,250$6.95M0.37%−91,500−85.7%Reduced
Wealth Enhancement Advisory Services, LLC14,525$6.68M0.01%+9,407+183.8%Added
Federation des caisses Desjardins du Quebec14,627$6.67M0.03%+7,078+93.8%Added
Cetera Investment Advisers14,523$6.62M0.01%+4,635+46.9%Added
Rakuten Investment Management, Inc.31,152$6.58M0.03%+31,152New
OP Asset Management Ltd14,386$6.56M0.09%+452+3.2%Added
Linden Advisors LP14,364$6.55M0.04%+14,364New
JustInvest LLC13,985$6.38M0.07%+595+4.4%Added
Aware Super Pty Ltd as trustee of Aware Super13,665$6.23M0.09%00.0%Unchanged
Tredje AP-fonden13,456$6.14M0.05%+1,254+10.3%Added
Wealthfront Advisers LLC13,420$6.12M0.01%+1,336+11.1%Added
Hantz Financial Services, Inc.13,146$6.00M0.09%+12,767+3,368.6%Added
The PNC Financial Services Group, Inc.13,115$5.98M0.00%−55−0.4%Reduced
Holocene Advisors, LP13,086$5.97M0.01%−583,730−97.8%Reduced
SRS Capital Advisors, Inc.13,085$5.97M0.09%+12,935+8,623.3%Added
Campbell & CO Investment Adviser LLC12,697$5.79M0.44%+12,697New
Fieldview Capital Management, LLC12,658$5.77M0.94%+12,658New
Public Employees Retirement Association of Colorado12,445$5.67M0.02%−396−3.1%Reduced
Trexquant Investment LP12,396$5.65M0.06%−8,147−39.7%Reduced
Nordea Investment Management AB12,481$5.65M0.00%+1,186+10.5%Added
Credit Agricole S A12,367$5.64M0.02%+12,367New
Nisa Investment Advisors, LLC12,133$5.53M0.02%+3,891+47.2%Added
CIBC World Markets Inc.12,116$5.52M0.01%+12,116New
Assetmark, Inc11,918$5.43M0.01%+375+3.2%Added
Zacks Investment Management11,904$5.43M0.04%−27−0.2%Reduced
Comerica Bank11,790$5.38M0.02%−6,827−36.7%Reduced
Alberta Investment Management Corp11,700$5.34M0.04%+11,700New
Liontrust Investment Partners LLP11,656$5.32M0.08%−1,113−8.7%Reduced
Virtu Financial LLC11,656$5.32M0.30%+11,656New
Dark Forest Capital Management LP11,598$5.29M0.20%+11,598New
Mercer Global Advisors Inc11,484$5.24M0.01%+8,921+348.1%Added
Raiffeisen Bank International AG11,609$5.19M0.07%+2,705+30.4%Added
Cullen/Frost Bankers, Inc.11,043$5.04M0.06%+248+2.3%Added
Traynor Capital Management, Inc.10,873$4.96M0.28%+668+6.5%Added
Silvercrest Asset Management Group LLC10,807$4.93M0.03%+556+5.4%Added
Mirae Asset Global ETFs Holdings Ltd.10,671$4.86M0.01%−887−7.7%Reduced
Schroder Investment Management Group10,818$4.84M0.00%+2,238+26.1%Added
Balyasny Asset Management LLC10,260$4.68M0.01%−105,015−91.1%Reduced
Blair William & Co10,244$4.67M0.01%−348−3.3%Reduced
Headlands Technologies LLC10,192$4.65M0.37%+10,192New
Amalgamated Bank10,144$4.63M0.03%+676+7.1%Added
Himension Fund10,094$4.60M0.28%−3,392−25.2%Reduced
Diadema Partners LP10,000$4.56M3.18%+10,000New
Bank of Montreal9,933$4.53M0.00%−3,178−24.2%Reduced
Employees Retirement System of Texas9,792$4.46M0.04%+318+3.4%Added
Mackenzie Financial Corp9,773$4.46M0.01%+698+7.7%Added
Lazard Asset Management LLC9,751$4.45M0.01%+2,001+25.8%Added
EFG Asset Management (Americas) Corp.9,738$4.44M0.77%−1,877−16.2%Reduced
Schonfeld Strategic Advisors LLC9,709$4.43M0.03%−49,048−83.5%Reduced
J. Safra Sarasin Holding AG9,522$4.34M0.07%−5,474−36.5%Reduced
Hudson Bay Capital Management LP9,411$4.29M0.03%−5,937−38.7%Reduced
Commonwealth Equity Services, LLC9,407$4.29M0.01%−519−5.2%Reduced
O'Shaughnessy Asset Management, LLC9,308$4.24M0.02%+2,872+44.6%Added
Prudential Financial Inc9,132$4.16M0.00%−74,790−89.1%Reduced
Motley Fool Asset Management LLC9,046$4.12M0.17%+2,394+36.0%Added
ASR Vermogensbeheer N.V.8,876$4.05M0.05%−50−0.6%Reduced
Guggenheim Capital LLC8,625$3.93M0.03%−2,024−19.0%Reduced
NWK Group, Inc.8,538$3.89M1.32%+8,538New
Catalyst Funds Management Pty Ltd8,320$3.79M0.58%−2,450−22.7%Reduced
Genus Capital Management Inc.8,260$3.77M0.44%+30+0.4%Added
S&CO Inc8,200$3.74M0.23%−1,850−18.4%Reduced
La Banque Postale Asset Management SA8,184$3.73M0.05%−138−1.7%Reduced
St Germain D J Co Inc8,151$3.72M0.15%−843−9.4%Reduced
MetLife Investment Management7,992$3.64M0.02%+231+3.0%Added
Kentucky Retirement Systems7,836$3.57M0.10%−417−5.1%Reduced
Wolverine Asset Management LLC7,800$3.56M0.05%+7,800New
Prudential PLC7,696$3.51M0.03%+3,584+87.2%Added
Captrust Financial Advisors7,669$3.50M0.01%+4,163+118.7%Added
NewEdge Wealth, LLC7,993$3.47M0.05%+7,091+786.1%Added
SummitTX Capital, L.P.7,525$3.43M0.14%+2,725+56.8%Added
Ci Investments Inc.7,224$3.29M0.01%+3,109+75.6%Added
J.P. Marvel Investment Advisors, LLC7,105$3.24M0.47%+281+4.1%Added
Advisory Services Network, LLC7,006$3.19M0.05%+591+9.2%Added
Toroso Investments, LLC6,891$3.14M0.01%+1,317+23.6%Added
Capula Management Ltd6,888$3.14M0.02%+6,888New