Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 793
- −48 vs. Q4 2025
- Shares held
- 131.4M
- +14.7M (+12.6%) vs. Q4 2025
- Total value
- $43.4B
- −$2.95B (−6.4%) vs. Q4 2025
- New holders
- 106
- 323 more added
- Sold out
- 154
- 258 more reduced
11 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 14,579,166 | $4.82B | 0.25% | −1,322,983−8.3% | Reduced |
| Capital World Investors | 10,802,348 | $3.57B | 0.49% | −5,499,424−33.7% | Reduced |
| BlackRock, Inc. | 10,444,908 | $3.46B | 0.06% | +44,034+0.4% | Added |
| Capital Research Global Investors | 9,471,181 | $3.13B | 0.49% | +2,691,473+39.7% | Added |
| Vanguard Portfolio Management LLC | 6,491,280 | $2.15B | 0.11% | +6,491,280 | New |
| JPMorgan Chase & Co | 6,323,752 | $2.00B | 0.14% | +1,603,753+34.0% | Added |
| Vanguard Capital Management LLC | 5,946,706 | $1.97B | 0.05% | +5,946,706 | New |
| T. Rowe Price Investment Management, Inc. | 5,193,324 | $1.72B | 1.18% | +3,439,684+196.1% | Added |
| Invesco Ltd. | 4,075,120 | $1.35B | 0.13% | −1,058,863−20.6% | Reduced |
| State Street Corp | 3,322,698 | $1.10B | 0.04% | +93,742+2.9% | Added |
| Geode Capital Management, LLC | 2,660,385 | $884.6M | 0.06% | +9,663+0.4% | Added |
| Baillie Gifford & Co | 2,493,866 | $825.1M | 0.84% | −107,113−4.1% | Reduced |
| Two Sigma Investments, LP | 1,992,577 | $659.3M | 0.55% | +1,376,457+223.4% | Added |
| Wellington Management Group LLP | 1,935,925 | $640.5M | 0.12% | +306,994+18.8% | Added |
| Dodge & Cox | 1,929,253 | $638.3M | 0.35% | −35,162−1.8% | Reduced |
| American Century Companies Inc | 1,802,363 | $596.3M | 0.31% | +317,202+21.4% | Added |
| Price T Rowe Associates Inc | 1,432,748 | $474.1M | 0.05% | −270,083−15.9% | Reduced |
| Clearbridge Investments, LLC | 1,356,036 | $448.7M | 0.39% | +759,023+127.1% | Added |
| Orbis Allan Gray Ltd | 1,334,825 | $441.7M | 1.86% | −283,394−17.5% | Reduced |
| Marshall Wace, LLP | 1,099,318 | $363.7M | 0.39% | +549,396+99.9% | Added |
| D. E. Shaw & Co., Inc. | 1,059,062 | $350.4M | 0.28% | +614,569+138.3% | Added |
| Morgan Stanley | 1,002,681 | $331.8M | 0.02% | +32,524+3.4% | Added |
| Bank of America Corp | 966,912 | $319.9M | 0.02% | +281,735+41.1% | Added |
| Legal & General Group Plc | 934,881 | $309.3M | 0.07% | −26,615−2.8% | Reduced |
| AQR Capital Management LLC | 913,104 | $297.9M | 0.14% | −6,855−0.7% | Reduced |
| Northern Trust Corp | 858,120 | $283.9M | 0.04% | +3780.0% | Added |
| Vanguard Fiduciary Trust Co | 840,888 | $278.2M | 0.07% | +840,888 | New |
| Qube Research & Technologies Ltd | 838,187 | $277.3M | 0.39% | +63,511+8.2% | Added |
| Royal Bank of Canada | 791,515 | $261.9M | 0.05% | +200,020+33.8% | Added |
| Deutsche Bank AG | 761,464 | $251.9M | 0.08% | +49,489+7.0% | Added |
| Amundi | 747,544 | $247.3M | 0.07% | +138,665+22.8% | Added |
| Federated Hermes, Inc. | 687,816 | $227.6M | 0.37% | +59,753+9.5% | Added |
| UBS Asset Management Americas Inc | 677,519 | $224.2M | 0.05% | +25,153+3.9% | Added |
| Charles Schwab Investment Management Inc | 673,356 | $222.8M | 0.03% | +25,517+3.9% | Added |
| Manufacturers Life Insurance Company, The | 662,365 | $219.2M | 0.19% | +598,953+944.5% | Added |
| Loomis Sayles & Co L P | 512,097 | $169.4M | 0.23% | +23,200+4.7% | Added |
| Massachusetts Financial Services Co | 496,004 | $164.1M | 0.06% | +697+0.1% | Added |
| Bank of New York Mellon Corp | 491,200 | $162.5M | 0.03% | −12,933−2.6% | Reduced |
| Franklin Resources Inc | 470,390 | $155.6M | 0.04% | −317,233−40.3% | Reduced |
| Goldman Sachs Group Inc | 469,388 | $155.3M | 0.02% | +94,065+25.1% | Added |
| UBS Group AG | 458,870 | $151.8M | 0.03% | −366,970−44.4% | Reduced |
| Millennium Management LLC | 447,887 | $148.2M | 0.11% | +372,457+493.8% | Added |
| Squarepoint Ops LLC | 426,723 | $141.2M | 0.30% | +75,754+21.6% | Added |
| Raymond James Financial Inc | 406,956 | $130.0M | 0.04% | +18,251+4.7% | Added |
| Swiss National Bank | 387,720 | $128.3M | 0.07% | +28,520+7.9% | Added |
| Dimensional Fund Advisors LP | 384,205 | $127.1M | 0.03% | +82,340+27.3% | Added |
| First Trust Advisors LP | 382,701 | $126.6M | 0.09% | +125,747+48.9% | Added |
| Wells Fargo & Company | 342,763 | $113.4M | 0.02% | +85,123+33.0% | Added |
| Nuveen, LLC | 322,232 | $106.6M | 0.03% | −243,557−43.0% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 314,417 | $104.0M | 0.07% | −13,346−4.1% | Reduced |
| Congress Asset Management Co | 285,739 | $94.5M | 0.68% | +16,500+6.1% | Added |
| TD Asset Management Inc | 281,848 | $93.3M | 0.08% | +12,747+4.7% | Added |
| BNP Paribas Arbitrage, SA | 280,965 | $93.0M | 0.06% | −108,470−27.9% | Reduced |
| Gilder Gagnon Howe & Co LLC | 280,092 | $92.7M | 1.11% | −39,213−12.3% | Reduced |
| Allspring Global Investments Holdings, LLC | 281,793 | $92.6M | 0.16% | +3,136+1.1% | Added |
| Pinebridge Investments LLC | 271,419 | $89.8M | 0.76% | +171,220+170.9% | Added |
| Citigroup Inc | 263,375 | $87.1M | 0.06% | +90,813+52.6% | Added |
| Nomura Asset Management International Inc. | 258,905 | $85.7M | 0.15% | −52,852−17.0% | Reduced |
| Polar Capital Holdings Plc | 257,674 | $85.3M | 0.37% | +17,068+7.1% | Added |
| Westfield Capital Management Co LP | 245,539 | $81.2M | 0.34% | +152,095+162.8% | Added |
| Woodline Partners LP | 243,883 | $80.7M | 0.31% | +242,124+13,764.9% | Added |
| Ameriprise Financial Inc | 239,941 | $79.4M | 0.02% | +58,804+32.5% | Added |
| Bellevue Group AG | 234,543 | $77.6M | 1.85% | −211,360−47.4% | Reduced |
| Pictet Asset Management Holding SA | 237,920 | $77.5M | 0.08% | −78,133−24.7% | Reduced |
| Man Group plc | 232,369 | $76.9M | 0.16% | +88,159+61.1% | Added |
| California Public Employees Retirement System | 227,997 | $75.4M | 0.05% | −9,008−3.8% | Reduced |
| Candriam Luxembourg S.C.A. | 224,330 | $74.2M | 0.39% | 00.0% | Unchanged |
| Barclays PLC | 220,623 | $73.0M | 0.03% | −1,938−0.9% | Reduced |
| Vanguard Asset Management, Ltd | 219,235 | $72.5M | 0.06% | +219,235 | New |
| Royal London Asset Management Ltd | 215,075 | $71.2M | 0.15% | −37,997−15.0% | Reduced |
| Jacobs Levy Equity Management, Inc | 212,204 | $70.2M | 0.30% | −189,167−47.1% | Reduced |
| Canada Pension Plan Investment Board | 208,938 | $69.1M | 0.04% | −49,773−19.2% | Reduced |
| Korea Investment CORP | 200,321 | $66.3M | 0.14% | +10,552+5.6% | Added |
| California State Teachers Retirement System | 196,863 | $65.1M | 0.07% | −4,953−2.5% | Reduced |
| Victory Capital Management Inc | 195,937 | $64.8M | 0.04% | −24,929−11.3% | Reduced |
| Rhumbline Advisers | 195,277 | $64.6M | 0.06% | +110.0% | Added |
| Voloridge Investment Management, LLC | 189,217 | $62.6M | 0.25% | +28,640+17.8% | Added |
| National Pension Service | 183,789 | $60.8M | 0.05% | +15,640+9.3% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 180,012 | $59.6M | 0.07% | +70,408+64.2% | Added |
| Life Cycle Investment Partners Ltd | 177,541 | $58.7M | 0.37% | +89,465+101.6% | Added |
| Susquehanna International Group, LLP | 174,268 | $57.7M | 0.07% | −17,552−9.2% | Reduced |
| ProShare Advisors LLC | 174,013 | $57.6M | 0.09% | −37,064−17.6% | Reduced |
| Envestnet Asset Management Inc | 171,797 | $56.8M | 0.02% | +51,276+42.5% | Added |
| CIBC Bancorp USA Inc. | 169,031 | $55.9M | 0.08% | +169,031 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 152,197 | $50.4M | 0.03% | +13,402+9.7% | Added |
| SCS Capital Management LLC | 149,547 | $49.5M | 0.52% | −640.0% | Reduced |
| Voya Investment Management LLC | 148,488 | $49.1M | 0.05% | −50,125−25.2% | Reduced |
| Janus Henderson Group PLC | 147,089 | $48.7M | 0.02% | +10,664+7.8% | Added |
| Russell Investments Group, Ltd. | 147,533 | $48.5M | 0.05% | −18,207−11.0% | Reduced |
| Antipodes Partners Ltd | 145,310 | $48.1M | 0.93% | +97,424+203.4% | Added |
| Capital Fund Management S.A. | 140,109 | $46.4M | 0.42% | +119,169+569.1% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 139,708 | $46.1M | 0.08% | +15,063+12.1% | Added |
| Standard Life Aberdeen plc | 138,331 | $45.8M | 0.07% | +5,485+4.1% | Added |
| Handelsbanken Fonder AB | 136,462 | $45.2M | 0.15% | +277+0.2% | Added |
| Brown Advisory Inc | 133,953 | $44.3M | 0.07% | +109,095+438.9% | Added |
| Soleus Capital Management, L.P. | 131,650 | $43.6M | 1.76% | +61,650+88.1% | Added |
| Assenagon Asset Management S.A. | 128,896 | $42.6M | 0.07% | +103,306+403.7% | Added |
| HRT Financial LP | 128,633 | $42.6M | 0.11% | +128,633 | New |
| Robeco Institutional Asset Management B.V. | 126,463 | $41.8M | 0.06% | −18,258−12.6% | Reduced |
| OrbiMed Advisors LLC | 119,000 | $39.4M | 0.89% | −169,800−58.8% | Reduced |