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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
443
+10 vs. Q4 2021
Shares held
114.0M
+1.95M (+1.7%) vs. Q4 2021
Total value
$18.6B
−$367.5M (−1.9%) vs. Q4 2021
New holders
68
154 more added
Sold out
58
149 more reduced

2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 443 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ1 2022: $18.6B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2021.

Institutions holding ALNY in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC16,045,316$2.62B0.21%−1,894,704−10.6%Reduced
Vanguard Group Inc10,829,144$1.77B0.04%+126,373+1.2%Added
Baillie Gifford & Co10,139,729$1.66B1.16%−477,022−4.5%Reduced
BlackRock Inc.7,608,954$1.24B0.03%−62,448−0.8%Reduced
Wellington Management Group LLP7,034,487$1.15B0.20%+190,057+2.8%Added
Price T Rowe Associates Inc6,794,166$1.11B0.11%+258,798+4.0%Added
Capital World Investors5,999,674$979.7M0.17%+5,680,728+1,781.1%Added
Dodge & Cox5,475,668$894.1M0.54%+44,600+0.8%Added
JPMorgan Chase & Co2,919,015$476.6M0.06%−53,070−1.8%Reduced
State Street Corp2,909,490$475.1M0.02%+59,101+2.1%Added
Manufacturers Life Insurance Company, The1,751,063$286.1M0.19%+48,393+2.8%Added
RTW Investments, LP1,683,362$274.9M5.69%−292,517−14.8%Reduced
Geode Capital Management, LLC1,570,283$256.0M0.03%+64,992+4.3%Added
Avoro Capital Advisors LLC1,300,000$212.3M3.88%+225,000+20.9%Added
Norges Bank1,295,087$211.5M0.05%+25,896+2.0%Added
Bellevue Group AG1,229,563$200.8M2.33%−105,577−7.9%Reduced
American Century Companies Inc1,131,844$184.8M0.13%+129,270+12.9%Added
Farallon Capital Management, L.L.C.1,023,873$167.2M0.92%−166,155−14.0%Reduced
Casdin Capital, LLC1,000,000$163.3M7.32%00.0%Unchanged
Invesco Ltd.968,755$158.2M0.04%+78,665+8.8%Added
Amundi874,950$142.0M0.10%+620,695+244.1%Added
Loomis Sayles & Co L P868,748$141.9M0.19%−127,689−12.8%Reduced
Morgan Stanley848,657$138.6M0.02%−217,032−20.4%Reduced
Holocene Advisors, LP799,222$130.5M0.69%+76,483+10.6%Added
Gilder Gagnon Howe & Co LLC791,224$129.2M1.19%−48,344−5.8%Reduced
Northern Trust Corp763,340$124.6M0.02%−6,073−0.8%Reduced
Legal & General Group Plc757,422$123.7M0.04%+77,852+11.5%Added
Goldman Sachs Group Inc681,553$111.3M0.03%−5,142−0.7%Reduced
Pictet Asset Management SA660,940$107.9M0.12%+46,948+7.6%Added
Artal Group S.A.650,000$106.1M4.49%00.0%Unchanged
Bank of New York Mellon Corp638,868$104.3M0.02%+36,554+6.1%Added
UBS Asset Management Americas Inc605,165$98.8M0.04%−35,545−5.5%Reduced
Janus Henderson Group PLC598,448$97.7M0.05%+97,115+19.4%Added
Swiss National Bank518,010$84.6M0.05%+66,300+14.7%Added
Blackstone Group Inc.517,391$84.5M0.21%00.0%Unchanged
Mitsubishi UFJ Trust & Banking Corp468,452$76.5M0.18%−2,559−0.5%Reduced
Deep Track Capital, LP463,663$75.7M4.89%+463,663New
Swedbank AB438,356$71.6M0.13%+1,791+0.4%Added
First Trust Advisors LP402,652$65.7M0.07%−104,444−20.6%Reduced
TD Asset Management Inc392,682$64.1M0.06%−3,791−1.0%Reduced
Rockefeller Capital Management L.P.373,964$61.1M0.29%−12,296−3.2%Reduced
Charles Schwab Investment Management Inc372,623$60.8M0.02%+9,662+2.7%Added
Nuveen Asset Management, LLC362,035$58.8M0.02%−228,509−38.7%Reduced
Rock Springs Capital Management LP332,500$54.3M1.37%00.0%Unchanged
Sumitomo Mitsui Trust Holdings, Inc.322,743$52.7M0.04%−1,709−0.5%Reduced
Eaton Vance Management306,228$50.0M0.06%+262,893+606.7%Added
Candriam Luxembourg S.C.A.303,653$49.6M0.34%+63,082+26.2%Added
Massachusetts Financial Services Co302,743$49.4M0.01%−1,019,468−77.1%Reduced
Deutsche Bank AG282,110$46.1M0.02%+7,462+2.7%Added
Bank of America Corp277,257$45.3M0.00%+12,779+4.8%Added
Eagle Asset Management Inc255,937$41.8M0.21%+607+0.2%Added
California Public Employees Retirement System245,603$40.1M0.03%−64,072−20.7%Reduced
Polar Capital Holdings Plc229,833$37.5M0.22%−305,798−57.1%Reduced
AXA S.A.207,896$33.9M0.10%−5,808−2.7%Reduced
California State Teachers Retirement System199,213$32.5M0.04%−10,519−5.0%Reduced
Franklin Resources Inc191,669$31.3M0.01%−18,638−8.9%Reduced
Parametric Portfolio Associates LLC189,206$30.9M0.02%−16,492−8.0%Reduced
New York State Common Retirement Fund186,700$30.5M0.03%−941−0.5%Reduced
Dimensional Fund Advisors LP181,271$29.6M0.01%+2,111+1.2%Added
National Pension Service180,898$29.5M0.05%+5,105+2.9%Added
Perceptive Advisors LLC180,079$29.4M0.61%+180,079New
Handelsbanken Fonder AB171,400$28.0M0.16%−16,400−8.7%Reduced
Tekla Capital Management LLC158,606$25.9M0.91%−31,089−16.4%Reduced
Tobam155,585$25.4M1.28%+73,732+90.1%Added
State Board of Administration of Florida Retirement System145,019$23.7M0.05%−2,974−2.0%Reduced
HighTower Advisors, LLC134,689$22.0M0.05%+5,036+3.9%Added
International Biotechnology Trust PLC38,000$21.7M9.54%−90,000−70.3%Reduced
Eagle Health Investments LP131,244$21.4M5.28%+17,542+15.4%Added
Rhenman & Partners Asset Management AB130,000$21.2M2.09%−45,000−25.7%Reduced
CIBC Private Wealth Group, LLC120,277$19.6M0.04%+2,025+1.7%Added
Credit Suisse AG119,610$19.5M0.02%+6,071+5.3%Added
State of Wisconsin Investment Board117,519$19.2M0.04%+24,318+26.1%Added
Artisan Partners Limited Partnership117,345$19.2M0.03%−121,791−50.9%Reduced
Rhumbline Advisers115,877$18.9M0.02%−3,955−3.3%Reduced
Van Eck Associates Corp100,006$16.3M0.03%+1,392+1.4%Added
LMR Partners LLP92,114$15.0M0.22%+69,886+314.4%Added
Nicholas Investment Partners, LP86,164$14.1M1.00%+86,164New
Morningstar Investment Services LLC83,831$13.9M0.15%+1,264+1.5%Added
Susquehanna International Group, LLP83,747$13.7M0.02%−59,208−41.4%Reduced
Lombard Odier Asset Management (Switzerland) SA83,038$13.6M1.06%+83,038New
USS Investment Management Ltd79,962$13.1M0.11%+4,222+5.6%Added
Barclays PLC79,598$13.0M0.01%−2,367−2.9%Reduced
Parnassus Investments77,587$12.7M0.03%00.0%Unchanged
Treasurer of the State of North Carolina77,559$12.7M0.07%+1,775+2.3%Added
Bank of Montreal73,751$12.4M0.01%+34,267+86.8%Added
Two Sigma Investments, LP73,949$12.1M0.04%+73,949New
Aviva PLC73,040$11.9M0.06%+34,823+91.1%Added
Adage Capital Partners GP, L.L.C.72,300$11.8M0.02%−60,000−45.4%Reduced
State of New Jersey Common Pension Fund D71,899$11.7M0.04%00.0%Unchanged
Jane Street Group, LLC67,563$11.0M0.02%−48,394−41.7%Reduced
BNP Paribas Arbitrage, SA66,700$10.9M0.02%+681+1.0%Added
Teachers Retirement System of the State of Kentucky66,123$10.8M0.11%+7,997+13.8%Added
Great West Life Assurance Co62,369$10.8M0.02%+10,892+21.2%Added
Mirae Asset Global Investments Co., Ltd.65,572$10.7M0.02%−9,597−12.8%Reduced
Wells Fargo & Company64,309$10.5M0.00%+19,142+42.4%Added
Millennium Management LLC63,957$10.4M0.01%−19,460−23.3%Reduced
Duquesne Family Office LLCSuperinvestorDuquesne Family Office63,945$10.4M0.48%+63,945New
Public Employees Retirement System of Ohio63,361$10.3M0.04%−1,430−2.2%Reduced
Nomura Asset Management Co Ltd62,910$10.3M0.06%−617−1.0%Reduced
Korea Investment CORP61,623$10.1M0.02%−1,439−2.3%Reduced