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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
443
+10 vs. Q4 2021
Shares held
114.0M
+1.95M (+1.7%) vs. Q4 2021
Total value
$18.6B
−$367.5M (−1.9%) vs. Q4 2021
New holders
68
154 more added
Sold out
58
149 more reduced

2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 443 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ1 2022: $18.6B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2021.

Institutions holding ALNY in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Sector Gamma AS59,251$9.68M2.10%+59,251New
DekaBank Deutsche Girozentrale57,168$9.52M0.02%+889+1.6%Added
Voya Investment Management LLC58,283$9.52M0.02%−444−0.8%Reduced
Citigroup Inc57,009$9.31M0.01%−12,301−17.7%Reduced
Alliancebernstein L.P.56,537$9.23M0.00%−13,343−19.1%Reduced
Driehaus Capital Management LLC54,449$8.89M0.11%−8,562−13.6%Reduced
Parkman Healthcare Partners LLC54,008$8.82M2.58%−3,674−6.4%Reduced
Eversept Partners, LP52,871$8.63M0.79%−17,369−24.7%Reduced
Asset Management One Co.,Ltd.50,233$8.20M0.03%−2,079−4.0%Reduced
683 Capital Management, LLC49,000$8.00M0.47%00.0%Unchanged
HSBC Holdings PLC47,827$7.82M0.01%+6,487+15.7%Added
Two Sigma Advisers, LP46,700$7.63M0.02%+42,900+1,128.9%Added
Storebrand Asset Management AS45,859$7.49M0.04%−6,996−13.2%Reduced
Allianz Asset Management GmbH44,928$7.34M0.01%−6,136−12.0%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.44,379$7.25M0.03%+43,121+3,427.7%Added
Macquarie Group Ltd43,211$7.06M0.01%+96+0.2%Added
Brown Advisory Inc42,608$6.96M0.01%+16,030+60.3%Added
Victory Capital Management Inc51,485$6.87M0.01%−4,877−8.7%Reduced
Rosenblum Silverman Sutton S F Inc41,761$6.82M1.75%−598−1.4%Reduced
Royal London Asset Management Ltd41,560$6.79M0.03%+1,257+3.1%Added
Russell Investments Group, Ltd.39,988$6.58M0.01%−35,680−47.2%Reduced
Banco Santander, S.A.40,000$6.53M0.07%+40,000New
Allspring Global Investments Holdings, LLC39,968$6.53M0.01%+14,121+54.6%Added
EFG Asset Management (North America) Corp.39,195$6.40M0.96%+39,195New
Squarepoint Ops LLC37,438$6.11M0.05%+37,438New
Rafferty Asset Management, LLC37,035$6.05M0.04%+5,090+15.9%Added
Karani Asset Management LLC36,960$6.04M3.26%+2,285+6.6%Added
Skandinaviska Enskilda Banken AB (publ)36,873$6.02M0.04%−9,616−20.7%Reduced
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund36,615$5.98M0.06%−3,300−8.3%Reduced
Ensign Peak Advisors, Inc36,430$5.95M0.01%−4,330−10.6%Reduced
Erste Asset Management GmbH35,930$5.94M0.11%−870−2.4%Reduced
Sabadell Asset Management, S.A S.G.I.I.C34,532$5.60M0.97%+34,532New
Federation des caisses Desjardins du Quebec33,575$5.48M0.05%+1,129+3.5%Added
Arizona State Retirement System33,292$5.44M0.04%+933+2.9%Added
Raymond James & Associates33,060$5.40M0.00%−10,443−24.0%Reduced
Twin Tree Management, LP31,784$5.19M0.10%+31,784New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.31,637$5.17M0.02%+1,918+6.5%Added
Majedie Asset Management Ltd31,529$5.14M0.42%+31,529New
Envestnet Asset Management Inc31,420$5.13M0.00%−2,893−8.4%Reduced
Jacobs Levy Equity Management, Inc31,274$5.11M0.03%−36,472−53.8%Reduced
Voloridge Investment Management, LLC29,380$4.80M0.03%+29,380New
Principal Financial Group Inc28,465$4.65M0.00%−1,557−5.2%Reduced
Cubist Systematic Strategies, LLC28,200$4.61M0.04%+10,534+59.6%Added
SEI Investments Co28,442$4.59M0.01%+3,001+11.8%Added
SG Americas Securities, LLC28,014$4.57M0.04%+19,168+216.7%Added
UBS Group AG27,976$4.57M0.00%−61,497−68.7%Reduced
Bridgeway Capital Management, LLC27,700$4.52M0.09%+27,700New
Gateway Investment Advisers LLC26,239$4.29M0.04%+21,671+474.4%Added
Taylor Wealth Management Partners26,056$4.25M1.72%−1,077−4.0%Reduced
Guggenheim Capital LLC25,744$4.20M0.03%−561−2.1%Reduced
Toronto Dominion Bank25,613$4.18M0.01%+2,185+9.3%Added
Novo Holdings A/S25,000$4.08M0.22%00.0%Unchanged
Sphera Funds Management Ltd.24,768$4.04M0.68%+24,768New
Teacher Retirement System of Texas24,543$4.01M0.02%+1,905+8.4%Added
Group One Trading, L.P.23,996$3.92M0.09%+2,854+13.5%Added
Forsta Ap-Fonden23,300$3.81M0.04%−500−2.1%Reduced
Prosight Management, LP22,704$3.71M2.61%−9,203−28.8%Reduced
Royal Bank of Canada22,595$3.69M0.00%−5,606−19.9%Reduced
Capital International Ltd21,839$3.57M0.20%+21,839New
Trexquant Investment LP21,496$3.51M0.16%+21,496New
Utah Retirement Systems21,372$3.49M0.05%−100−0.5%Reduced
DnB Asset Management AS21,355$3.49M0.02%+1,868+9.6%Added
Gulf International Bank (UK) Ltd19,911$3.25M0.05%00.0%Unchanged
Jefferies Group LLC19,788$3.23M0.07%−12,171−38.1%Reduced
Capital International Inc19,390$3.17M0.04%+19,390New
Mackenzie Financial Corp19,376$3.16M0.00%+1,965+11.3%Added
DCF Advisers, LLC19,000$3.10M1.82%+1,000+5.6%Added
IFM Investors Pty Ltd18,978$3.10M0.05%+3,046+19.1%Added
British Columbia Investment Management Corp18,462$3.02M0.02%−2,486−11.9%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)18,409$3.01M0.01%+144+0.8%Added
ETF Managers Group, LLC16,900$2.79M0.06%−5,379−24.1%Reduced
EFG Asset Management (Americas) Corp.16,738$2.73M0.51%+16,738New
LPL Financial LLC16,608$2.71M0.00%+714+4.5%Added
Westwood Holdings Group Inc.16,380$2.67M0.02%−1,676−9.3%Reduced
CWM Advisors, LLC15,733$2.57M0.30%−2,803−15.1%Reduced
Public Employees Retirement Association of Colorado15,690$2.56M0.01%−773−4.7%Reduced
Zeke Capital Advisors, LLC15,633$2.55M0.13%+1,278+8.9%Added
The PNC Financial Services Group, Inc.15,510$2.53M0.00%+10.0%Added
ProShare Advisors LLC15,190$2.48M0.01%−4,656−23.5%Reduced
Profund Advisors LLC14,975$2.44M0.10%−1,471−8.9%Reduced
D. E. Shaw & Co., Inc.14,883$2.43M0.00%−31,457−67.9%Reduced
Susquehanna Fundamental Investments, LLC14,180$2.31M0.05%+7,892+125.5%Added
Tower Research Capital LLC (TRC)14,135$2.31M0.02%+7,404+110.0%Added
Nissay Asset Management Corp14,023$2.29M0.02%+386+2.8%Added
Xponance, Inc.13,783$2.25M0.04%+387+2.9%Added
Exchange Traded Concepts, LLC13,532$2.21M0.04%+4,618+51.8%Added
Amalgamated Bank13,355$2.18M0.02%+2,877+27.5%Added
Amalgamated Financial Corp.13,355$2.18M0.02%+13,355New
Capital International Sarl13,315$2.17M0.11%+13,315New
Wealthfront Advisers LLC12,845$2.10M0.01%+11,526+873.8%Added
National Bank of Canada12,189$2.04M0.01%+7,382+153.6%Added
Ameriprise Financial Inc12,652$2.02M0.00%+115+0.9%Added
Stifel Financial Corp12,176$1.99M0.00%−2,500−17.0%Reduced
Vident Investment Advisory, LLC12,161$1.98M0.05%+5,136+73.1%Added
First Foundation Advisors12,034$1.97M0.07%−2,430−16.8%Reduced
Comerica Bank11,666$1.96M0.01%−9−0.1%Reduced
Raymond James Financial Services Advisors, Inc.11,850$1.94M0.00%+1,017+9.4%Added
Banque Pictet & Cie SA11,774$1.92M0.01%−4,707−28.6%Reduced
Bamco Inc11,500$1.88M0.00%+11,500New
AQR Capital Management LLC11,247$1.84M0.00%+9,123+429.5%Added