Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 435
- +36 vs. Q3 2021
- Shares held
- 112.1M
- +547.7K (+0.5%) vs. Q3 2021
- Total value
- $19.0B
- −$2.05B (−9.7%) vs. Q3 2021
- New holders
- 77
- 156 more added
- Sold out
- 41
- 132 more reduced
8 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 17,940,020 | $3.04B | 0.22% | +113,092+0.6% | Added |
| Vanguard Group Inc | 10,702,771 | $1.81B | 0.04% | +88,189+0.8% | Added |
| Baillie Gifford & Co | 10,616,751 | $1.80B | 0.99% | +200,967+1.9% | Added |
| BlackRock Inc. | 7,671,402 | $1.30B | 0.03% | −1,249,570−14.0% | Reduced |
| Wellington Management Group LLP | 6,844,430 | $1.16B | 0.19% | −526,642−7.1% | Reduced |
| Price T Rowe Associates Inc | 6,535,368 | $1.11B | 0.10% | +661,133+11.3% | Added |
| Dodge & Cox | 5,431,068 | $921.0M | 0.57% | +58,968+1.1% | Added |
| JPMorgan Chase & Co | 2,972,085 | $504.0M | 0.06% | +526,426+21.5% | Added |
| State Street Corp | 2,850,389 | $483.4M | 0.02% | +49,564+1.8% | Added |
| RTW Investments, LP | 1,975,879 | $335.1M | 4.89% | +292,517+17.4% | Added |
| Manufacturers Life Insurance Company, The | 1,702,670 | $289.1M | 0.18% | −28,763−1.7% | Reduced |
| Geode Capital Management, LLC | 1,505,291 | $254.9M | 0.03% | +51,272+3.5% | Added |
| Bellevue Group AG | 1,335,140 | $226.4M | 2.33% | −73,278−5.2% | Reduced |
| Massachusetts Financial Services Co | 1,322,211 | $224.2M | 0.06% | −43,076−3.2% | Reduced |
| Norges Bank | 1,269,191 | $215.2M | 0.04% | +274,303+27.6% | Added |
| Farallon Capital Management, L.L.C. | 1,190,028 | $201.8M | 1.14% | +375,727+46.1% | Added |
| Avoro Capital Advisors LLC | 1,075,000 | $182.3M | 3.10% | +225,000+26.5% | Added |
| Morgan Stanley | 1,065,689 | $180.7M | 0.02% | −815,190−43.3% | Reduced |
| American Century Companies Inc | 1,002,574 | $170.0M | 0.11% | −68,897−6.4% | Reduced |
| Casdin Capital, LLC | 1,000,000 | $169.6M | 4.78% | 00.0% | Unchanged |
| Loomis Sayles & Co L P | 996,437 | $169.0M | 0.20% | +28,330+2.9% | Added |
| Federated Hermes, Inc. | 992,180 | $168.3M | 0.31% | +33,360+3.5% | Added |
| Invesco Ltd. | 890,090 | $150.9M | 0.04% | −164,082−15.6% | Reduced |
| Gilder Gagnon Howe & Co LLC | 839,568 | $142.4M | 0.81% | −84,116−9.1% | Reduced |
| Northern Trust Corp | 769,413 | $130.5M | 0.02% | −9,708−1.2% | Reduced |
| Holocene Advisors, LP | 722,739 | $122.6M | 0.65% | +61,509+9.3% | Added |
| Goldman Sachs Group Inc | 686,695 | $116.5M | 0.03% | +20,240+3.0% | Added |
| Legal & General Group Plc | 679,570 | $115.2M | 0.03% | +12,785+1.9% | Added |
| Artal Group S.A. | 650,000 | $110.2M | 3.24% | −50,000−7.1% | Reduced |
| UBS Asset Management Americas Inc | 640,710 | $108.7M | 0.04% | −4,862−0.8% | Reduced |
| Pictet Asset Management SA | 613,992 | $104.1M | 0.10% | −209,712−25.5% | Reduced |
| Bank of New York Mellon Corp | 602,314 | $102.1M | 0.02% | +149,064+32.9% | Added |
| Nuveen Asset Management, LLC | 590,544 | $100.1M | 0.03% | −176,488−23.0% | Reduced |
| Polar Capital Holdings Plc | 535,631 | $90.8M | 0.47% | +11,919+2.3% | Added |
| Blackstone Group Inc. | 517,391 | $87.7M | 0.22% | 00.0% | Unchanged |
| First Trust Advisors LP | 507,096 | $86.0M | 0.08% | −25,190−4.7% | Reduced |
| Janus Henderson Group PLC | 501,333 | $85.0M | 0.04% | +479,756+2,223.5% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 471,011 | $79.9M | 0.17% | −15,837−3.3% | Reduced |
| Swiss National Bank | 451,710 | $76.6M | 0.05% | −12,900−2.8% | Reduced |
| Swedbank AB | 436,565 | $74.7M | 0.13% | +670.0% | Added |
| TD Asset Management Inc | 396,473 | $67.2M | 0.06% | +161,789+68.9% | Added |
| Rockefeller Capital Management L.P. | 386,260 | $65.5M | 0.31% | +68,160+21.4% | Added |
| Avidity Partners Management LP | 370,000 | $62.7M | 1.33% | −57,000−13.3% | Reduced |
| Charles Schwab Investment Management Inc | 362,961 | $61.6M | 0.02% | +10,146+2.9% | Added |
| Rock Springs Capital Management LP | 332,500 | $56.4M | 1.30% | +21,500+6.9% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 324,452 | $55.0M | 0.03% | −8,119−2.4% | Reduced |
| Capital World Investors | 318,946 | $54.1M | 0.01% | 00.0% | Unchanged |
| California Public Employees Retirement System | 309,675 | $52.5M | 0.04% | −9,284−2.9% | Reduced |
| Deutsche Bank AG | 274,648 | $46.6M | 0.02% | −7,514−2.7% | Reduced |
| Bank of America Corp | 264,478 | $44.8M | 0.00% | −39,706−13.1% | Reduced |
| Eagle Asset Management Inc | 255,330 | $43.7M | 0.19% | +1,549+0.6% | Added |
| Candriam Luxembourg S.C.A. | 240,571 | $40.8M | 0.26% | +107,492+80.8% | Added |
| Artisan Partners Limited Partnership | 239,136 | $40.6M | 0.05% | −3,648−1.5% | Reduced |
| Amundi | 254,255 | $37.6M | 0.02% | −6,114−2.3% | Reduced |
| AXA S.A. | 213,704 | $36.2M | 0.09% | +52,272+32.4% | Added |
| Franklin Resources Inc | 210,307 | $35.7M | 0.01% | +60,652+40.5% | Added |
| California State Teachers Retirement System | 209,732 | $35.6M | 0.04% | +4,340+2.1% | Added |
| Parametric Portfolio Associates LLC | 205,698 | $34.9M | 0.02% | −2,839−1.4% | Reduced |
| Tekla Capital Management LLC | 189,695 | $32.2M | 1.04% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 187,800 | $31.8M | 0.16% | +167,700+834.3% | Added |
| New York State Common Retirement Fund | 187,641 | $31.8M | 0.03% | +6,717+3.7% | Added |
| Dimensional Fund Advisors LP | 179,160 | $30.4M | 0.01% | −8,103−4.3% | Reduced |
| Rhenman & Partners Asset Management AB | 175,000 | $29.9M | 1.99% | +75,000+75.0% | Added |
| National Pension Service | 175,793 | $29.8M | 0.05% | −5,310−2.9% | Reduced |
| Assenagon Asset Management S.A. | 174,443 | $29.6M | 0.11% | −159,846−47.8% | Reduced |
| State Board of Administration of Florida Retirement System | 147,993 | $25.1M | 0.05% | −2,091−1.4% | Reduced |
| Susquehanna International Group, LLP | 142,955 | $24.2M | 0.04% | +98,562+222.0% | Added |
| Adage Capital Partners GP, L.L.C. | 132,300 | $22.4M | 0.04% | +132,300 | New |
| HighTower Advisors, LLC | 129,653 | $22.0M | 0.05% | +123,016+1,853.5% | Added |
| International Biotechnology Trust PLC | 128,000 | $21.7M | 4.84% | +53,000+70.7% | Added |
| Rhumbline Advisers | 119,832 | $20.3M | 0.02% | +3,723+3.2% | Added |
| CIBC Private Wealth Group, LLC | 118,252 | $20.1M | 0.04% | −893−0.7% | Reduced |
| Jane Street Group, LLC | 115,957 | $19.7M | 0.04% | +100,355+643.2% | Added |
| Eagle Health Investments LP | 113,702 | $19.3M | 4.70% | +23,600+26.2% | Added |
| Credit Suisse AG | 113,539 | $19.3M | 0.02% | −44,147−28.0% | Reduced |
| Natixis | 104,062 | $17.6M | 0.06% | +1,546+1.5% | Added |
| Van Eck Associates Corp | 98,614 | $16.7M | 0.04% | +5,913+6.4% | Added |
| EcoR1 Capital, LLC | 98,146 | $16.6M | 0.53% | +98,146 | New |
| State of Wisconsin Investment Board | 93,201 | $15.8M | 0.03% | −6,189−6.2% | Reduced |
| UBS Group AG | 89,473 | $15.2M | 0.01% | +67,281+303.2% | Added |
| Millennium Management LLC | 83,417 | $14.1M | 0.02% | +71,585+605.0% | Added |
| Morningstar Investment Services LLC | 82,567 | $14.0M | 0.16% | +1,973+2.4% | Added |
| Barclays PLC | 81,965 | $13.9M | 0.01% | −15,510−15.9% | Reduced |
| Tobam | 81,853 | $13.9M | 0.62% | +72,659+790.3% | Added |
| Balyasny Asset Management LLC | 81,241 | $13.8M | 0.06% | +41,097+102.4% | Added |
| Parnassus Investments | 77,587 | $13.2M | 0.03% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 75,668 | $12.9M | 0.02% | +17,891+31.0% | Added |
| USS Investment Management Ltd | 75,740 | $12.9M | 0.10% | 00.0% | Unchanged |
| Treasurer of the State of North Carolina | 75,784 | $12.9M | 0.07% | −520−0.7% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 75,169 | $12.8M | 0.03% | −9,294−11.0% | Reduced |
| State of New Jersey Common Pension Fund D | 71,899 | $12.2M | 0.04% | 00.0% | Unchanged |
| Citadel Advisors LLC | 70,768 | $12.0M | 0.01% | +49,889+238.9% | Added |
| Eversept Partners, LP | 70,240 | $11.9M | 0.99% | +11,007+18.6% | Added |
| Alliancebernstein L.P. | 69,880 | $11.8M | 0.00% | +3,194+4.8% | Added |
| Citigroup Inc | 69,310 | $11.8M | 0.01% | −1,682−2.4% | Reduced |
| Jacobs Levy Equity Management, Inc | 67,746 | $11.5M | 0.08% | +67,746 | New |
| BNP Paribas Arbitrage, SA | 66,019 | $11.2M | 0.03% | −11,162−14.5% | Reduced |
| Public Employees Retirement System of Ohio | 64,791 | $11.0M | 0.04% | −2,219−3.3% | Reduced |
| Nomura Asset Management Co Ltd | 63,527 | $10.8M | 0.05% | +20,703+48.3% | Added |
| Korea Investment CORP | 63,062 | $10.7M | 0.03% | +39,762+170.7% | Added |