Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 625
- +39 vs. Q4 2024
- Shares held
- 129.4M
- +2.10M (+1.7%) vs. Q4 2024
- Total value
- $34.8B
- +$4.88B (+16.3%) vs. Q4 2024
- New holders
- 106
- 235 more added
- Sold out
- 67
- 205 more reduced
8 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital World Investors | 16,749,623 | $4.52B | 0.73% | +149,098+0.9% | Added |
| FMR LLC | 15,309,860 | $4.13B | 0.26% | +1,823,957+13.5% | Added |
| Vanguard Group Inc | 13,056,605 | $3.53B | 0.06% | +323,206+2.5% | Added |
| BlackRock, Inc. | 9,559,382 | $2.58B | 0.05% | −325,875−3.3% | Reduced |
| Capital Research Global Investors | 7,154,728 | $1.93B | 0.42% | +186,215+2.7% | Added |
| Regeneron Pharmaceuticals, Inc. | 4,444,445 | $1.20B | 97.23% | 00.0% | Unchanged |
| T. Rowe Price Investment Management, Inc. | 4,418,145 | $1.19B | 0.79% | +33,696+0.8% | Added |
| Baillie Gifford & Co | 3,657,607 | $987.6M | 0.86% | −382,652−9.5% | Reduced |
| Price T Rowe Associates Inc | 3,505,168 | $946.5M | 0.12% | +185,783+5.6% | Added |
| State Street Corp | 3,366,583 | $909.0M | 0.04% | −56,294−1.6% | Reduced |
| Dodge & Cox | 3,351,762 | $905.0M | 0.52% | −188,500−5.3% | Reduced |
| Wellington Management Group LLP | 2,610,986 | $705.0M | 0.14% | −1,585,637−37.8% | Reduced |
| Geode Capital Management, LLC | 2,322,834 | $625.8M | 0.05% | +116,034+5.3% | Added |
| JPMorgan Chase & Co | 2,218,872 | $599.1M | 0.05% | −31,188−1.4% | Reduced |
| Norges Bank | 2,136,024 | $576.8M | 0.08% | −320,058−13.0% | Reduced |
| American Century Companies Inc | 1,760,435 | $475.4M | 0.29% | +156,411+9.8% | Added |
| Orbis Allan Gray Ltd | 1,634,923 | $441.5M | 2.53% | +162,121+11.0% | Added |
| Winslow Capital Management, LLC | 1,187,178 | $320.6M | 1.28% | +166,611+16.3% | Added |
| Bank of America Corp | 1,064,573 | $287.5M | 0.03% | +646,021+154.3% | Added |
| Invesco Ltd. | 913,792 | $246.7M | 0.05% | +355,302+63.6% | Added |
| Legal & General Group Plc | 881,111 | $237.9M | 0.06% | +52,194+6.3% | Added |
| Northern Trust Corp | 865,020 | $233.6M | 0.03% | −13,840−1.6% | Reduced |
| AQR Capital Management LLC | 828,344 | $217.0M | 0.22% | +14,988+1.8% | Added |
| Bellevue Group AG | 768,147 | $207.4M | 4.65% | −2,121−0.3% | Reduced |
| UBS Asset Management Americas Inc | 736,111 | $198.8M | 0.05% | +25,513+3.6% | Added |
| Morgan Stanley | 641,765 | $173.3M | 0.01% | −85,459−11.8% | Reduced |
| Deutsche Bank AG | 576,993 | $155.8M | 0.06% | +20,414+3.7% | Added |
| Nuveen, LLC | 883,374 | $148.7M | 0.05% | +883,374 | New |
| Charles Schwab Investment Management Inc | 546,642 | $147.6M | 0.03% | +32,680+6.4% | Added |
| Loomis Sayles & Co L P | 497,484 | $134.3M | 0.19% | −5,561−1.1% | Reduced |
| TD Asset Management Inc | 486,584 | $131.4M | 0.12% | −17,454−3.5% | Reduced |
| Pictet Asset Management Holding SA | 480,967 | $129.7M | 0.14% | +50,355+11.7% | Added |
| Bank of New York Mellon Corp | 474,832 | $128.2M | 0.03% | −4,371−0.9% | Reduced |
| Franklin Resources Inc | 458,314 | $123.8M | 0.04% | +44,175+10.7% | Added |
| Amundi | 454,995 | $119.3M | 0.04% | −41,306−8.3% | Reduced |
| Goldman Sachs Group Inc | 423,367 | $114.3M | 0.02% | +116,912+38.1% | Added |
| Swiss National Bank | 364,200 | $98.3M | 0.07% | +1,600+0.4% | Added |
| OrbiMed Advisors LLC | 346,100 | $93.5M | 2.24% | −69,500−16.7% | Reduced |
| Gilder Gagnon Howe & Co LLC | 345,575 | $93.3M | 1.22% | −19,888−5.4% | Reduced |
| Royal Bank of Canada | 337,231 | $91.1M | 0.02% | +27,044+8.7% | Added |
| Qube Research & Technologies Ltd | 330,347 | $89.2M | 0.14% | −154,913−31.9% | Reduced |
| Dimensional Fund Advisors LP | 309,819 | $83.6M | 0.02% | −23,842−7.1% | Reduced |
| Jennison Associates LLC | 309,219 | $83.5M | 0.06% | +49,306+19.0% | Added |
| Point72 Asset Management, L.P. | 300,635 | $81.2M | 0.23% | +300,635 | New |
| Wells Fargo & Company | 300,080 | $81.0M | 0.02% | +23,118+8.3% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 291,476 | $78.7M | 0.06% | +4,773+1.7% | Added |
| D. E. Shaw & Co., Inc. | 289,862 | $78.3M | 0.09% | −73,223−20.2% | Reduced |
| Millennium Management LLC | 287,337 | $77.6M | 0.08% | −46,105−13.8% | Reduced |
| Royal London Asset Management Ltd | 286,943 | $77.5M | 0.18% | +5,434+1.9% | Added |
| Adage Capital Partners GP, L.L.C. | 282,184 | $76.2M | 0.14% | +189,128+203.2% | Added |
| Polar Capital Holdings Plc | 280,000 | $75.6M | 0.47% | −30,000−9.7% | Reduced |
| UBS Group AG | 278,638 | $75.2M | 0.02% | −11,328−3.9% | Reduced |
| SEI Investments Co | 277,369 | $74.9M | 0.10% | +11,369+4.3% | Added |
| Two Sigma Advisers, LP | 275,800 | $74.5M | 0.17% | +197,000+250.0% | Added |
| Raymond James Financial Inc | 268,970 | $72.6M | 0.03% | −8,516−3.1% | Reduced |
| Marshall Wace, LLP | 268,932 | $72.6M | 0.10% | −109,717−29.0% | Reduced |
| Federated Hermes, Inc. | 264,173 | $71.3M | 0.15% | +14,582+5.8% | Added |
| Allspring Global Investments Holdings, LLC | 270,924 | $69.3M | 0.12% | +270,924 | New |
| Candriam Luxembourg S.C.A. | 249,919 | $67.5M | 0.42% | −32,488−11.5% | Reduced |
| Allianz Asset Management GmbH | 218,503 | $59.0M | 0.09% | +109,632+100.7% | Added |
| Standard Life Aberdeen plc | 215,385 | $57.1M | 0.11% | +24,544+12.9% | Added |
| California Public Employees Retirement System | 201,481 | $54.4M | 0.04% | −2,651−1.3% | Reduced |
| California State Teachers Retirement System | 197,443 | $53.3M | 0.07% | +1,081+0.6% | Added |
| Two Sigma Investments, LP | 197,415 | $53.3M | 0.12% | +90,298+84.3% | Added |
| Citigroup Inc | 194,734 | $52.6M | 0.04% | +107,837+124.1% | Added |
| Westfield Capital Management Co LP | 192,172 | $51.9M | 0.25% | −23,954−11.1% | Reduced |
| Worldquant Millennium Advisors LLC | 191,105 | $51.6M | 0.33% | +40,914+27.2% | Added |
| Rhumbline Advisers | 181,463 | $49.0M | 0.05% | +1,885+1.0% | Added |
| Janus Henderson Group PLC | 181,649 | $48.8M | 0.03% | −28,431−13.5% | Reduced |
| First Trust Advisors LP | 180,460 | $48.7M | 0.04% | −147,322−44.9% | Reduced |
| Sofinnova Investments, Inc. | 176,181 | $47.6M | 3.59% | +66,024+59.9% | Added |
| National Pension Service | 173,659 | $46.9M | 0.05% | +14,148+8.9% | Added |
| Prudential Financial Inc | 172,006 | $46.4M | 0.07% | +153,253+817.2% | Added |
| SCS Capital Management LLC | 171,077 | $46.2M | 0.59% | +171,077 | New |
| CIBC Private Wealth Group, LLC | 205,511 | $46.1M | 0.10% | +2,143+1.1% | Added |
| Eventide Asset Management, LLC | 166,450 | $44.9M | 0.90% | −73,968−30.8% | Reduced |
| Antipodes Partners Ltd | 159,554 | $43.1M | 1.35% | +25,795+19.3% | Added |
| Woodline Partners LP | 156,464 | $42.2M | 0.27% | +156,464 | New |
| Jacobs Levy Equity Management, Inc | 152,970 | $41.3M | 0.16% | +152,970 | New |
| Deerfield Management Company, L.P. (Series C) | 145,000 | $39.2M | 0.78% | −191−0.1% | Reduced |
| 1832 Asset Management L.P. | 144,045 | $38.9M | 0.07% | +144,045 | New |
| Rock Springs Capital Management LP | 143,250 | $38.7M | 2.21% | −112,950−44.1% | Reduced |
| SG Americas Securities, LLC | 132,960 | $35.9M | 0.12% | +131,293+7,876.0% | Added |
| Russell Investments Group, Ltd. | 129,196 | $34.9M | 0.05% | +56,036+76.6% | Added |
| State Board of Administration of Florida Retirement System | 125,240 | $33.8M | 0.07% | 00.0% | Unchanged |
| Capital International Sarl | 121,160 | $32.7M | 0.74% | +6,018+5.2% | Added |
| Casdin Capital, LLC | 120,000 | $32.4M | 2.65% | −20,000−14.3% | Reduced |
| FIL Ltd | 117,862 | $31.8M | 0.03% | +95,796+434.1% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 117,720 | $31.8M | 0.06% | −6,640−5.3% | Reduced |
| Handelsbanken Fonder AB | 116,683 | $31.5M | 0.13% | +62,337+114.7% | Added |
| HighTower Advisors, LLC | 113,857 | $30.7M | 0.04% | −1,523−1.3% | Reduced |
| DekaBank Deutsche Girozentrale | 113,042 | $30.0M | 0.06% | −151−0.1% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 110,665 | $29.9M | 0.08% | −6,021−5.2% | Reduced |
| Ameriprise Financial Inc | 109,136 | $29.5M | 0.01% | −18,937−14.8% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 105,879 | $28.6M | 0.03% | +11,181+11.8% | Added |
| Korea Investment CORP | 105,759 | $28.6M | 0.07% | +12,156+13.0% | Added |
| Robeco Institutional Asset Management B.V. | 103,481 | $27.9M | 0.05% | +3,487+3.5% | Added |
| Frontier Capital Management Co LLC | 102,420 | $27.7M | 0.30% | −2,298−2.2% | Reduced |
| Manufacturers Life Insurance Company, The | 98,869 | $26.7M | 0.03% | −10,233−9.4% | Reduced |
| Jane Street Group, LLC | 98,551 | $26.6M | 0.05% | −62,086−38.6% | Reduced |