Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 489
- +1 vs. Q3 2022
- Shares held
- 119.5M
- −13.5M (−10.2%) vs. Q3 2022
- Total value
- $28.4B
- +$1.76B (+6.6%) vs. Q3 2022
- New holders
- 85
- 178 more added
- Sold out
- 84
- 149 more reduced
9 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital World Investors | 16,390,275 | $3.90B | 0.83% | +2,440,628+17.5% | Added |
| FMR LLC | 13,512,083 | $3.21B | 0.32% | +562,325+4.3% | Added |
| Vanguard Group Inc | 11,507,116 | $2.73B | 0.07% | +453,808+4.1% | Added |
| Baillie Gifford & Co | 9,407,871 | $2.24B | 2.33% | −106,887−1.1% | Reduced |
| BlackRock Inc. | 8,489,380 | $2.02B | 0.06% | +820,702+10.7% | Added |
| Wellington Management Group LLP | 6,234,086 | $1.48B | 0.30% | +279,793+4.7% | Added |
| Dodge & Cox | 4,590,782 | $1.09B | 0.75% | −298,515−6.1% | Reduced |
| Price T Rowe Associates Inc | 4,074,144 | $968.2M | 0.16% | +353,538+9.5% | Added |
| T. Rowe Price Investment Management, Inc. | 3,202,793 | $761.1M | 0.58% | +10,609+0.3% | Added |
| JPMorgan Chase & Co | 3,127,694 | $743.3M | 0.11% | +582,662+22.9% | Added |
| State Street Corp | 2,786,542 | $662.2M | 0.04% | −8,943−0.3% | Reduced |
| Capital International Investors | 2,005,621 | $476.6M | 0.13% | +58,907+3.0% | Added |
| Geode Capital Management, LLC | 1,689,929 | $401.1M | 0.06% | +90,455+5.7% | Added |
| RTW Investments, LP | 1,683,362 | $400.1M | 8.17% | 00.0% | Unchanged |
| Morgan Stanley | 1,390,640 | $330.5M | 0.04% | −108,119−7.2% | Reduced |
| Avoro Capital Advisors LLC | 1,105,000 | $262.6M | 3.92% | 00.0% | Unchanged |
| Norges Bank | 1,012,846 | $240.7M | 0.06% | −205,338−16.9% | Reduced |
| Bellevue Group AG | 921,213 | $218.9M | 2.91% | −35,549−3.7% | Reduced |
| Capital Research Global Investors | 832,117 | $197.8M | 0.06% | +832,117 | New |
| Massachusetts Financial Services Co | 755,542 | $179.6M | 0.06% | +219,943+41.1% | Added |
| Northern Trust Corp | 749,539 | $178.1M | 0.04% | +15,547+2.1% | Added |
| Legal & General Group Plc | 732,355 | $174.0M | 0.07% | −22,137−2.9% | Reduced |
| Loomis Sayles & Co L P | 712,556 | $169.3M | 0.34% | −35,194−4.7% | Reduced |
| American Century Companies Inc | 699,795 | $166.3M | 0.14% | +6,788+1.0% | Added |
| Invesco Ltd. | 669,849 | $159.2M | 0.05% | −67,981−9.2% | Reduced |
| UBS Asset Management Americas Inc | 657,920 | $156.4M | 0.08% | +54,388+9.0% | Added |
| Gilder Gagnon Howe & Co LLC | 649,617 | $154.4M | 2.88% | −14,366−2.2% | Reduced |
| Amundi | 667,533 | $150.3M | 0.08% | −528,376−44.2% | Reduced |
| Nuveen Asset Management, LLC | 618,644 | $147.0M | 0.06% | −15,974,624−96.3% | Reduced |
| Holocene Advisors, LP | 598,928 | $142.3M | 0.88% | −44,721−6.9% | Reduced |
| Bank of New York Mellon Corp | 574,385 | $136.5M | 0.03% | +7,247+1.3% | Added |
| Lord, Abbett & Co. LLC | 523,972 | $124.5M | 0.44% | +4,840+0.9% | Added |
| Swiss National Bank | 488,100 | $116.0M | 0.08% | −35,510−6.8% | Reduced |
| Janus Henderson Group PLC | 465,388 | $110.6M | 0.08% | −109,116−19.0% | Reduced |
| Deutsche Bank AG | 465,053 | $110.5M | 0.06% | +211,369+83.3% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 460,175 | $109.4M | 0.29% | −14,473−3.0% | Reduced |
| Pictet Asset Management SA | 441,562 | $104.9M | 0.15% | −234,247−34.7% | Reduced |
| Swedbank AB | 426,653 | $101.4M | 0.22% | +10,593+2.5% | Added |
| First Trust Advisors LP | 420,560 | $99.9M | 0.12% | −74,372−15.0% | Reduced |
| Charles Schwab Investment Management Inc | 400,576 | $95.2M | 0.03% | +21,711+5.7% | Added |
| Goldman Sachs Group Inc | 392,761 | $93.3M | 0.03% | −72,546−15.6% | Reduced |
| TD Asset Management Inc | 392,450 | $93.3M | 0.12% | +7,639+2.0% | Added |
| 1832 Asset Management L.P. | 391,345 | $93.0M | 0.19% | +4,200+1.1% | Added |
| Casdin Capital, LLC | 365,000 | $86.7M | 6.77% | −283,000−43.7% | Reduced |
| Manufacturers Life Insurance Company, The | 343,220 | $81.6M | 0.05% | −567,340−62.3% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 336,976 | $80.1M | 0.06% | −1,709−0.5% | Reduced |
| Rock Springs Capital Management LP | 332,500 | $79.0M | 1.90% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 320,495 | $76.2M | 0.51% | −32,553−9.2% | Reduced |
| Bank of America Corp | 303,209 | $72.1M | 0.01% | +65,400+27.5% | Added |
| Polar Capital Holdings Plc | 297,500 | $70.7M | 0.56% | +182,500+158.7% | Added |
| California Public Employees Retirement System | 270,883 | $64.4M | 0.05% | +1,123+0.4% | Added |
| Eagle Asset Management Inc | 263,673 | $61.6M | 0.38% | +153+0.1% | Added |
| Voloridge Investment Management, LLC | 210,011 | $49.9M | 0.28% | +138,481+193.6% | Added |
| California State Teachers Retirement System | 201,731 | $47.9M | 0.08% | +3,380+1.7% | Added |
| AXA S.A. | 201,416 | $47.9M | 0.17% | +13,576+7.2% | Added |
| Wells Fargo & Company | 199,416 | $47.4M | 0.01% | +135,604+212.5% | Added |
| Royal Bank of Canada | 196,580 | $46.7M | 0.01% | +130,564+197.8% | Added |
| Citigroup Inc | 196,261 | $46.6M | 0.07% | +12,231+6.6% | Added |
| Dimensional Fund Advisors LP | 194,576 | $46.2M | 0.02% | +18,310+10.4% | Added |
| Handelsbanken Fonder AB | 192,294 | $45.7M | 0.29% | +64,701+50.7% | Added |
| Voya Investment Management LLC | 185,199 | $44.0M | 0.05% | +99,505+116.1% | Added |
| Two Sigma Investments, LP | 182,707 | $43.4M | 0.14% | −34,005−15.7% | Reduced |
| D. E. Shaw & Co., Inc. | 176,416 | $41.9M | 0.07% | +25,272+16.7% | Added |
| Barclays PLC | 162,134 | $38.5M | 0.03% | +20,780+14.7% | Added |
| Franklin Resources Inc | 160,845 | $38.2M | 0.02% | +1,550+1.0% | Added |
| National Pension Service | 156,230 | $37.1M | 0.07% | −757−0.5% | Reduced |
| Eagle Health Investments LP | 155,716 | $37.0M | 8.54% | −6,000−3.7% | Reduced |
| New York State Common Retirement Fund | 154,698 | $36.8M | 0.05% | +6,680+4.5% | Added |
| Rhumbline Advisers | 148,396 | $35.3M | 0.05% | +11,711+8.6% | Added |
| Tekla Capital Management LLC | 143,214 | $34.0M | 1.29% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 137,032 | $32.6M | 0.08% | −1,760−1.3% | Reduced |
| Farallon Capital Management, L.L.C. | 130,056 | $30.9M | 0.20% | −298,400−69.6% | Reduced |
| Aviva PLC | 129,840 | $30.9M | 0.15% | +42,365+48.4% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 126,847 | $30.1M | 0.11% | +61,583+94.4% | Added |
| Credit Suisse AG | 126,079 | $30.0M | 0.03% | +12,570+11.1% | Added |
| HighTower Advisors, LLC | 125,742 | $29.9M | 0.07% | −1,122−0.9% | Reduced |
| APG Asset Management N.V. | 125,190 | $29.8M | 0.06% | +101,998+439.8% | Added |
| CIBC Private Wealth Group, LLC | 121,866 | $28.6M | 0.10% | +2,458+2.1% | Added |
| Two Sigma Advisers, LP | 120,000 | $28.5M | 0.08% | +56,200+88.1% | Added |
| Jane Street Group, LLC | 118,976 | $28.3M | 0.05% | −154,013−56.4% | Reduced |
| Tobam | 116,048 | $27.6M | 1.83% | +15,183+15.1% | Added |
| Novo Holdings A/S | 112,000 | $26.6M | 1.66% | +12,000+12.0% | Added |
| Tang Capital Management LLC | 105,000 | $25.0M | 3.63% | +5,000+5.0% | Added |
| Woodline Partners LP | 95,068 | $22.6M | 0.31% | +95,068 | New |
| Van Eck Associates Corp | 92,380 | $22.0M | 0.06% | +22,484+32.2% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 91,566 | $21.8M | 0.16% | −24,873−21.4% | Reduced |
| DekaBank Deutsche Girozentrale | 90,353 | $21.3M | 0.06% | +1,962+2.2% | Added |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 88,910 | $21.1M | 1.05% | 00.0% | Unchanged |
| Capital International Ltd | 88,045 | $20.9M | 1.44% | +20,030+29.4% | Added |
| Treasurer of the State of North Carolina | 86,367 | $20.5M | 0.12% | +1,880+2.2% | Added |
| State of Wisconsin Investment Board | 85,434 | $20.3M | 0.07% | −4,935−5.5% | Reduced |
| Rhenman & Partners Asset Management AB | 73,000 | $17.3M | 1.81% | −2,000−2.7% | Reduced |
| State of New Jersey Common Pension Fund D | 72,232 | $17.2M | 0.06% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 71,184 | $16.9M | 0.01% | −3,784−5.0% | Reduced |
| Driehaus Capital Management LLC | 69,251 | $16.5M | 0.25% | +1,169+1.7% | Added |
| Public Employees Retirement System of Ohio | 68,099 | $16.2M | 0.07% | +6,707+10.9% | Added |
| Capital International Sarl | 66,876 | $15.9M | 1.12% | +22,551+50.9% | Added |
| Canada Pension Plan Investment Board | 62,123 | $14.8M | 0.03% | −9,060−12.7% | Reduced |
| Teachers Retirement System of the State of Kentucky | 61,053 | $14.5M | 0.15% | +1,596+2.7% | Added |
| Neuberger Berman Group LLC | 60,770 | $14.4M | 0.01% | +55,952+1,161.3% | Added |