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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
435
+36 vs. Q3 2021
Shares held
112.1M
+547.7K (+0.5%) vs. Q3 2021
Total value
$19.0B
−$2.05B (−9.7%) vs. Q3 2021
New holders
77
156 more added
Sold out
41
132 more reduced

8 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 435 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2021: $19.0B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2021.

Institutions holding ALNY in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Driehaus Capital Management LLC63,011$10.7M0.11%+18,509+41.6%Added
Voya Investment Management LLC58,727$9.96M0.02%+21,248+56.7%Added
Teachers Retirement System of the State of Kentucky58,126$9.86M0.09%+5,835+11.2%Added
Parkman Healthcare Partners LLC57,682$9.78M2.21%−17,285−23.1%Reduced
Victory Capital Management Inc56,362$9.56M0.01%+484+0.9%Added
DekaBank Deutsche Girozentrale56,279$9.54M0.02%+11,843+26.7%Added
Canada Pension Plan Investment Board56,137$9.52M0.01%−35,151−38.5%Reduced
Storebrand Asset Management AS52,855$8.96M0.04%−452−0.8%Reduced
Asset Management One Co.,Ltd.52,312$8.90M0.03%−336−0.6%Reduced
Great West Life Assurance Co51,477$8.71M0.02%−15,739−23.4%Reduced
Allianz Asset Management GmbH51,064$8.67M0.01%−4,490−8.1%Reduced
683 Capital Management, LLC49,000$8.31M0.40%00.0%Unchanged
Skandinaviska Enskilda Banken AB (publ)46,489$7.95M0.04%+5,200+12.6%Added
D. E. Shaw & Co., Inc.46,340$7.86M0.01%+13,277+40.2%Added
Wells Fargo & Company45,167$7.66M0.00%−91,083−66.8%Reduced
Raymond James & Associates43,503$7.38M0.01%+3,802+9.6%Added
Eaton Vance Management43,335$7.35M0.01%−674−1.5%Reduced
Macquarie Group Ltd43,115$7.31M0.01%−10,478−19.6%Reduced
Rosenblum Silverman Sutton S F Inc42,359$7.18M1.62%−665−1.5%Reduced
Lord, Abbett & Co. LLC42,000$7.12M0.02%−238,000−85.0%Reduced
HSBC Holdings PLC41,340$7.02M0.01%+12,626+44.0%Added
Ensign Peak Advisors, Inc40,760$6.91M0.01%−127,839−75.8%Reduced
Bank of Montreal39,484$6.85M0.00%−13,857−26.0%Reduced
Royal London Asset Management Ltd40,303$6.84M0.03%−977−2.4%Reduced
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund39,915$6.77M0.06%−969−2.4%Reduced
Aviva PLC38,217$6.48M0.03%+1,965+5.4%Added
Erste Asset Management GmbH36,800$6.26M0.11%00.0%Unchanged
Logos Global Management LP35,000$5.93M0.61%+35,000New
Karani Asset Management LLC34,675$5.88M2.91%+2,186+6.7%Added
Envestnet Asset Management Inc34,313$5.82M0.00%+2,828+9.0%Added
Federation des caisses Desjardins du Quebec32,446$5.50M0.05%−1,569−4.6%Reduced
Arizona State Retirement System32,359$5.49M0.04%−629−1.9%Reduced
Jefferies Group LLC31,959$5.42M0.10%+18,515+137.7%Added
Rafferty Asset Management, LLC31,945$5.42M0.03%+15,515+94.4%Added
Prosight Management, LP31,907$5.41M3.60%+31,907New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.29,719$5.17M0.02%+1,087+3.8%Added
Principal Financial Group Inc30,022$5.09M0.00%−8,618−22.3%Reduced
PointState Capital LP30,000$5.09M0.16%+18,000+150.0%Added
Ghost Tree Capital, LLC30,000$5.09M1.95%+30,000New
Andra AP-fonden28,400$4.82M0.10%+8,500+42.7%Added
Royal Bank of Canada28,201$4.78M0.00%+3,609+14.7%Added
Taylor Wealth Management Partners27,133$4.60M1.62%−696−2.5%Reduced
Brown Advisory Inc26,578$4.51M0.01%+26,578New
Guggenheim Capital LLC26,305$4.46M0.02%+2,461+10.3%Added
SEI Investments Co25,441$4.42M0.01%+1,379+5.7%Added
Allspring Global Investments Holdings, LLC25,847$4.38M0.00%+25,847New
Novo Holdings A/S25,000$4.24M0.20%00.0%Unchanged
Brookfield Asset Management Inc.24,352$4.13M0.02%+24,352New
Tudor Investment Corp Et Al24,057$4.08M0.08%−4,196−14.9%Reduced
Forsta Ap-Fonden23,800$4.04M0.04%+500+2.1%Added
Toronto Dominion Bank23,428$3.97M0.01%+8,089+52.7%Added
Teacher Retirement System of Texas22,638$3.84M0.02%−6,797−23.1%Reduced
Nomura Holdings Inc22,403$3.81M0.02%+20,674+1,195.7%Added
ETF Managers Group, LLC22,279$3.81M0.08%−3,423−13.3%Reduced
LMR Partners LLP22,228$3.77M0.05%+22,228New
Edgestream Partners, L.P.21,987$3.73M0.23%+5,566+33.9%Added
Utah Retirement Systems21,472$3.64M0.04%00.0%Unchanged
Group One Trading, L.P.21,142$3.58M0.07%+9,356+79.4%Added
British Columbia Investment Management Corp20,948$3.55M0.02%−711−3.3%Reduced
Integral Health Asset Management, LLC20,000$3.39M0.95%−5,000−20.0%Reduced
Varma Mutual Pension Insurance Co20,000$3.39M0.05%+20,000New
Gulf International Bank (UK) Ltd19,911$3.38M0.05%−3,700−15.7%Reduced
ProShare Advisors LLC19,846$3.37M0.01%−8,361−29.6%Reduced
DnB Asset Management AS19,487$3.30M0.02%+1,670+9.4%Added
CWM Advisors, LLC18,536$3.14M0.36%+3,781+25.6%Added
Zurcher Kantonalbank (Zurich Cantonalbank)18,265$3.10M0.01%−8,836−32.6%Reduced
Goldstream Capital Management Ltd18,096$3.07M0.75%+18,096New
Westwood Holdings Group Inc.18,056$3.06M0.03%+6,928+62.3%Added
DCF Advisers, LLC18,000$3.05M1.54%+500+2.9%Added
Cubist Systematic Strategies, LLC17,666$3.00M0.03%+778+4.6%Added
Mackenzie Financial Corp17,411$2.95M0.00%+1,756+11.2%Added
SG3 Management, LLC17,000$2.88M0.29%−23,250−57.8%Reduced
Banque Pictet & Cie SA16,481$2.79M0.02%+16,481New
Public Employees Retirement Association of Colorado16,463$2.79M0.01%00.0%Unchanged
Profund Advisors LLC16,446$2.79M0.09%−2,826−14.7%Reduced
IFM Investors Pty Ltd15,932$2.70M0.05%−59−0.4%Reduced
LPL Financial LLC15,894$2.69M0.00%+2,792+21.3%Added
The PNC Financial Services Group, Inc.15,509$2.63M0.00%+60.0%Added
Stifel Financial Corp14,676$2.49M0.00%+674+4.8%Added
First Foundation Advisors14,464$2.45M0.08%+600+4.3%Added
Zeke Capital Advisors, LLC14,355$2.43M0.14%+1,274+9.7%Added
Nissay Asset Management Corp13,637$2.31M0.02%+371+2.8%Added
Xponance, Inc.13,396$2.27M0.04%+9+0.1%Added
Natixis Advisors, L.P.12,523$2.12M0.01%−7,329−36.9%Reduced
Ameriprise Financial Inc12,537$2.07M0.00%+1,823+17.0%Added
Duality Advisers, LP12,173$2.06M0.22%−4,631−27.6%Reduced
CWM, LLC11,998$2.04M0.01%+11,998New
Cutler Group LP11,582$1.96M0.13%+11,582New
Standard Life Aberdeen plc11,167$1.89M0.00%+382+3.5%Added
Employees Retirement System of Texas11,018$1.87M0.02%00.0%Unchanged
Beacon Investment Advisory Services, Inc.11,013$1.87M0.07%+1,732+18.7%Added
Allstate Corp10,859$1.84M0.04%+5,490+102.3%Added
Raymond James Financial Services Advisors, Inc.10,833$1.84M0.00%+520+5.0%Added
Cullen/Frost Bankers, Inc.10,549$1.79M0.03%00.0%Unchanged
Amalgamated Bank10,478$1.78M0.01%+3,602+52.4%Added
Cookson Peirce & Co Inc9,728$1.65M0.09%+500+5.4%Added
US Bancorp9,599$1.63M0.00%+1,008+11.7%Added
AtonRa Partners9,432$1.60M0.56%+748+8.6%Added
Maryland State Retirement & Pension System9,099$1.54M0.04%+272+3.1%Added
MML Investors Services, LLC9,043$1.53M0.01%+814+9.9%Added