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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
435
+36 vs. Q3 2021
Shares held
112.1M
+547.7K (+0.5%) vs. Q3 2021
Total value
$19.0B
−$2.05B (−9.7%) vs. Q3 2021
New holders
77
156 more added
Sold out
41
132 more reduced

8 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 435 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2021: $19.0B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2021.

Institutions holding ALNY in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Comerica Bank11,675$1.53M0.01%−20.0%Reduced
Exchange Traded Concepts, LLC8,914$1.51M0.03%−177−1.9%Reduced
SG Americas Securities, LLC8,846$1.50M0.01%−2,041−18.7%Reduced
Westpac Banking Corp8,524$1.45M0.01%−2,445−22.3%Reduced
Daiwa Securities Group Inc.8,419$1.43M0.01%−76−0.9%Reduced
Virtu Financial LLC8,307$1.41M0.14%+8,307New
APG Asset Management N.V.8,997$1.34M0.00%−3,482−27.9%Reduced
Metropolitan Life Insurance Co7,891$1.34M0.02%−61−0.8%Reduced
Sectoral Asset Management Inc7,596$1.29M0.19%−68,250−90.0%Reduced
Truist Financial Corp7,595$1.29M0.00%+992+15.0%Added
Seeyond7,444$1.26M0.12%00.0%Unchanged
Verition Fund Management LLC7,386$1.25M0.02%+6,318+591.6%Added
Nordea Investment Management AB7,146$1.25M0.00%+1,994+38.7%Added
Vontobel Holding Ltd.7,236$1.24M0.01%+3,991+123.0%Added
KBC Group NV7,239$1.23M0.00%−7,610−51.2%Reduced
Sumitomo Mitsui DS Asset Management Company, Ltd7,146$1.21M0.03%+1,197+20.1%Added
Nisa Investment Advisors, LLC8,767$1.21M0.01%−21,760−71.3%Reduced
HighVista Strategies LLC7,093$1.20M0.96%+935+15.2%Added
Vident Investment Advisory, LLC7,025$1.19M0.03%−4,255−37.7%Reduced
Cinctive Capital Management LP6,990$1.19M0.06%+6,990New
Tower Research Capital LLC (TRC)6,731$1.14M0.02%+5,835+651.2%Added
Orion Capital Management LLC6,665$1.13M0.64%−10−0.1%Reduced
E. Ohman J:or Asset Management AB6,400$1.09M0.03%+6,400New
Alpine Global Management, LLC6,334$1.07M0.16%+6,334New
Susquehanna Fundamental Investments, LLC6,288$1.07M0.03%00.0%Unchanged
Connectus Wealth, LLC6,200$1.05M0.04%+6,200New
Values First Advisors, Inc.6,149$1.04M0.62%−368−5.6%Reduced
Advisor Group Holdings, Inc.5,848$994.0K0.00%+418+7.7%Added
Cushing Asset Management, LP5,821$987.0K0.10%−383−6.2%Reduced
Shell Asset Management Co5,808$985.0K0.02%+2,053+54.7%Added
ExodusPoint Capital Management, LP5,745$974.0K0.01%+5,745New
Schroder Investment Management Group5,711$968.0K0.00%+758+15.3%Added
Blueshift Asset Management, LLC5,702$967.0K0.09%+2,276+66.4%Added
First Hawaiian Bank5,700$967.0K0.03%+5,700New
Aevitas Wealth Management, Inc.5,457$925.0K0.55%00.0%Unchanged
CIBC Asset Management Inc5,359$909.0K0.00%+581+12.2%Added
Prudential Financial Inc4,992$905.0K0.00%+1,040+26.3%Added
Commonwealth Equity Services, LLC5,211$883.0K0.00%+942+22.1%Added
Maven Securities LTD5,086$862.0K0.11%+5,086New
Brewin Dolphin Ltd5,000$848.0K0.04%+855+20.6%Added
Pearl River Capital, LLC4,901$831.0K0.22%+4,901New
PEAK6 Investments LLC4,704$798.0K0.02%+4,704New
National Bank of Canada4,807$796.0K0.00%+4,807New
Brandywine Managers, LLC4,608$781.0K0.88%00.0%Unchanged
Gateway Investment Advisers LLC4,568$775.0K0.01%−6−0.1%Reduced
Commerce Bank4,258$722.0K0.00%+21+0.5%Added
D.A. Davidson & Co.4,229$717.0K0.01%+187+4.6%Added
Livingston Group Asset Management CO (operating as Southport Capital Management)4,175$708.0K0.12%+4,175New
J.P. Marvel Investment Advisors, LLC4,008$680.0K0.13%+4,008New
Echo Street Capital Management LLC3,931$667.0K0.00%+2,111+116.0%Added
Cresset Asset Management, LLC3,852$654.0K0.01%+1,402+57.2%Added
Private Advisor Group, LLC3,825$649.0K0.00%−1,149−23.1%Reduced
Two Sigma Advisers, LP3,800$644.0K0.00%+3,800New
Impax Asset Management Group plc3,791$642.0K0.00%−12,521−76.8%Reduced
Walleye Capital LLC3,772$640.0K0.02%+104+2.8%Added
Davenport & Co LLC3,705$628.0K0.00%+288+8.4%Added
Wolverine Trading, LLC3,626$620.0K0.01%+1,482+69.1%Added
Advisors Asset Management, Inc.3,644$618.0K0.01%−49−1.3%Reduced
Spectrum Planning & Advisory Services Inc.3,635$616.0K0.56%00.0%Unchanged
M&T Bank Corp3,587$608.0K0.00%+15+0.4%Added
Qube Research & Technologies Ltd3,527$598.0K0.00%−41,372−92.1%Reduced
Sanders Morris Harris LLC3,500$596.0K0.10%00.0%Unchanged
Citizens Business Bank3,500$594.0K0.07%00.0%Unchanged
Astrantus Ltd3,420$580.0K0.43%+3,420New
Kornitzer Capital Management Inc3,360$570.0K0.01%00.0%Unchanged
Panagora Asset Management Inc3,342$567.0K0.00%−2,667−44.4%Reduced
Walleye Trading LLC3,305$560.0K0.01%+1,705+106.6%Added
Cambridge Investment Research Advisors, Inc.3,276$556.0K0.00%−56−1.7%Reduced
Neuberger Berman Group LLC3,701$553.0K0.00%+3,701New
Hall Laurie J Trustee3,250$551.0K0.20%−550−14.5%Reduced
Greenleaf Trust3,187$540.0K0.01%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd3,134$531.0K0.13%+3,134New
Clearstead Advisors, LLC3,110$527.0K0.04%+110+3.7%Added
Advisory Research Inc3,089$524.0K0.04%−213−6.5%Reduced
Spearhead Capital Advisors, LLC3,082$523.0K0.06%+165+5.7%Added
Horizon Kinetics Asset Management LLC3,000$509.0K0.01%00.0%Unchanged
Lloyd Park, LLC3,000$509.0K0.40%+3,000New
Emerald Advisers, LLC2,990$507.0K0.02%−42−1.4%Reduced
Cetera Advisor Networks LLC2,986$506.0K0.01%+225+8.1%Added
Dai-Ichi Life Insurance Company, Ltd2,939$498.0K0.01%−418−12.5%Reduced
JustInvest LLC2,889$490.0K0.03%+438+17.9%Added
Agf Investments Inc.2,882$489.0K0.00%−529−15.5%Reduced
Oppenheimer & Co Inc2,843$482.0K0.01%+504+21.5%Added
TD Waterhouse Canada Inc.2,876$481.8K0.00%+2,876New
Brinker Capital Investments, LLC2,822$479.0K0.01%+349+14.1%Added
Banque Cantonale Vaudoise2,800$475.0K0.02%−300−9.7%Reduced
AlphaCrest Capital Management LLC2,789$473.0K0.02%−2,119−43.2%Reduced
Azzad Asset Management Inc2,687$455.6K0.06%+2,687New
Redpoint Investment Management Pty Ltd2,490$422.0K0.03%00.0%Unchanged
VELA Investment Management, LLC2,431$412.0K0.28%+2,431New
Privium Fund Management B.V.2,400$410.0K0.08%+2,400New
New York Life Investments Alternatives2,398$407.0K0.27%+2,398New
B. Metzler seel. Sohn & Co. AG2,319$397.0K0.01%+2,319New
Corient Capital Partners, LLC2,312$392.0K0.03%+38+1.7%Added
Argent Trust Co2,257$383.0K0.02%+31+1.4%Added
American International Group, Inc.2,251$382.0K0.00%−78−3.3%Reduced
Veriti Management LLC2,187$371.0K0.05%+87+4.1%Added
Toroso Investments, LLC2,181$370.0K0.01%−193−8.1%Reduced
Monograph Wealth Advisors, LLC2,134$362.0K0.09%+2,134New
AQR Capital Management LLC2,124$360.0K0.00%+2,124New