Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 823
- +178 vs. Q2 2025
- Shares held
- 129.9M
- −193.8K (−0.1%) vs. Q2 2025
- Total value
- $59.2B
- +$16.8B (+39.6%) vs. Q2 2025
- New holders
- 225
- 283 more added
- Sold out
- 47
- 223 more reduced
8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| M&T Bank Corp | 6,802 | $3.10M | 0.01% | −1,401−17.1% | Reduced |
| Winton Group Ltd | 6,800 | $3.10M | 0.12% | +3,267+92.5% | Added |
| BI Asset Management Fondsmaeglerselskab A/S | 6,705 | $3.06M | 0.03% | −207−3.0% | Reduced |
| Colony Group, LLC | 6,617 | $2.99M | 0.00% | +3,467+110.1% | Added |
| Truist Financial Corp | 6,466 | $2.95M | 0.00% | +2,459+61.4% | Added |
| Gulf International Bank (UK) Ltd | 6,378 | $2.91M | 0.10% | −117−1.8% | Reduced |
| Pathstone Holdings, LLC | 6,297 | $2.87M | 0.01% | +221+3.6% | Added |
| Point72 Asset Management, L.P. | 6,197 | $2.83M | 0.01% | −195,199−96.9% | Reduced |
| Maryland State Retirement & Pension System | 6,186 | $2.82M | 0.06% | +165+2.7% | Added |
| Sanctuary Advisors, LLC | 6,175 | $2.82M | 0.02% | +2,103+51.6% | Added |
| Brevan Howard Capital Management LP | 6,170 | $2.81M | 0.04% | +6,170 | New |
| Mirae Asset Global Investments Co., Ltd. | 6,160 | $2.81M | 0.01% | +1,385+29.0% | Added |
| Wolverine Trading, LLC | 6,262 | $2.80M | 0.06% | +5,140+458.1% | Added |
| Thematics Asset Management | 6,125 | $2.79M | 0.13% | +7+0.1% | Added |
| Bridgeway Capital Management, LLC | 6,030 | $2.75M | 0.06% | +6,030 | New |
| Bank of Nova Scotia | 5,944 | $2.71M | 0.00% | +3,265+121.9% | Added |
| Intech Investment Management LLC | 5,812 | $2.65M | 0.02% | +1,404+31.9% | Added |
| AustralianSuper Pty Ltd | 5,742 | $2.62M | 0.01% | +1,524+36.1% | Added |
| E. Ohman J:or Asset Management AB | 5,700 | $2.60M | 0.06% | 00.0% | Unchanged |
| US Bancorp | 5,646 | $2.57M | 0.00% | +946+20.1% | Added |
| Gilbert & Cook, Inc. | 5,508 | $2.51M | 0.32% | +1,514+37.9% | Added |
| CIBC Asset Management Inc | 5,498 | $2.51M | 0.01% | +40+0.7% | Added |
| Dai-Ichi Life Insurance Company, Ltd | 5,455 | $2.49M | 0.06% | +2,000+57.9% | Added |
| Mirabella Financial Services LLP | 5,447 | $2.48M | 0.22% | +2,477+83.4% | Added |
| Principal Financial Group Inc | 5,420 | $2.47M | 0.00% | −45,114−89.3% | Reduced |
| Brinker Capital Investments, LLC | 5,398 | $2.46M | 0.02% | +1,089+25.3% | Added |
| West Michigan Advisors, LLC | 5,396 | $2.46M | 0.59% | +5,396 | New |
| Vident Advisory, LLC | 5,237 | $2.39M | 0.02% | +1,312+33.4% | Added |
| Atria Investments LLC | 5,194 | $2.37M | 0.03% | +918+21.5% | Added |
| Gateway Investment Advisers LLC | 5,141 | $2.34M | 0.02% | −748−12.7% | Reduced |
| Buckingham Strategic Partners | 5,127 | $2.28M | 0.03% | +4,317+533.0% | Added |
| Susquehanna Portfolio Strategies, LLC | 5,005 | $2.28M | 0.04% | 00.0% | Unchanged |
| Brighton Jones LLC | 4,941 | $2.25M | 0.05% | +3,909+378.8% | Added |
| Burney Co | 4,883 | $2.23M | 0.07% | −259−5.0% | Reduced |
| Plato Investment Management Ltd | 4,906 | $2.22M | 0.15% | +793+19.3% | Added |
| Banque Cantonale Vaudoise | 4,860 | $2.22M | 0.08% | −883−15.4% | Reduced |
| CIBC Bancorp USA Inc. | 4,675 | $2.13M | 0.01% | +4,675 | New |
| Integrated Wealth Concepts LLC | 4,636 | $2.11M | 0.02% | +1,191+34.6% | Added |
| ProShare Advisors LLC | 4,631 | $2.11M | 0.00% | +390+9.2% | Added |
| Donoghue Forlines LLC | 4,627 | $2.11M | 0.65% | +4,627 | New |
| Azzad Asset Management Inc | 4,620 | $2.11M | 0.21% | +1,969+74.3% | Added |
| Allstate Corp | 4,571 | $2.08M | 0.05% | +4,571 | New |
| Highland Capital Management, LLC | 4,569 | $2.08M | 0.10% | +4,569 | New |
| Aigen Investment Management, LP | 4,538 | $2.07M | 0.32% | +4,538 | New |
| Commerce Bank | 4,531 | $2.07M | 0.01% | −5−0.1% | Reduced |
| Advisors Asset Management, Inc. | 4,522 | $2.06M | 0.03% | −23−0.5% | Reduced |
| Omers Administration Corp | 4,517 | $2.06M | 0.01% | 00.0% | Unchanged |
| Tokio Marine Asset Management Co Ltd | 4,444 | $2.03M | 0.07% | +4,444 | New |
| Pallas Capital Advisors LLC | 4,425 | $2.02M | 0.07% | +1,855+72.2% | Added |
| Rockefeller Capital Management L.P. | 4,380 | $2.00M | 0.00% | +4,380 | New |
| Metis Global Partners, LLC | 4,311 | $1.97M | 0.05% | −326−7.0% | Reduced |
| Sequoia Financial Advisors, LLC | 4,306 | $1.96M | 0.01% | +389+9.9% | Added |
| Oppenheimer Asset Management Inc. | 4,300 | $1.96M | 0.02% | +2,972+223.8% | Added |
| Soros Fund Management LLCSuperinvestorSoros Fund Management | 4,295 | $1.96M | 0.03% | +4,295 | New |
| Empowered Funds, LLC | 4,285 | $1.95M | 0.02% | +1,432+50.2% | Added |
| Howland Capital Management LLC | 4,243 | $1.93M | 0.07% | +243+6.1% | Added |
| Merit Financial Group, LLC | 4,232 | $1.93M | 0.02% | +2,342+123.9% | Added |
| AG2R la Mondiale Gestion D'Actifs | 5,825 | $1.90M | 0.10% | 00.0% | Unchanged |
| Polar Asset Management Partners Inc. | 4,104 | $1.87M | 0.04% | −5,496−57.3% | Reduced |
| Moore Capital Management, LP | 4,104 | $1.87M | 0.04% | +4,104 | New |
| Shaolin Capital Management LLC | 4,104 | $1.87M | 0.09% | +4,104 | New |
| Sona Asset Management (US) LLC | 4,104 | $1.87M | 0.07% | +4,104 | New |
| Keybank National Association | 4,060 | $1.85M | 0.01% | +1,303+47.3% | Added |
| Knollwood Investment Advisory, LLC | 4,059 | $1.85M | 0.17% | −1,296−24.2% | Reduced |
| Janney Montgomery Scott LLC | 4,055 | $1.85M | 0.00% | +4,055 | New |
| Atlantic Trust, LLC | 3,994 | $1.82M | 0.31% | −286−6.7% | Reduced |
| B. Metzler seel. Sohn & Co. AG | 3,913 | $1.78M | 0.02% | +680+21.0% | Added |
| Values First Advisors, Inc. | 3,882 | $1.77M | 0.95% | −65−1.6% | Reduced |
| Scientech Research LLC | 3,872 | $1.77M | 0.62% | +3,872 | New |
| Brandywine Managers, LLC | 3,718 | $1.70M | 1.63% | −500−11.9% | Reduced |
| Krilogy Financial LLC | 3,822 | $1.66M | 0.06% | +3,822 | New |
| Profund Advisors LLC | 3,536 | $1.61M | 0.05% | −2,882−44.9% | Reduced |
| Inceptionr LLC | 3,519 | $1.60M | 0.39% | −1,057−23.1% | Reduced |
| Bamco Inc | 3,500 | $1.60M | 0.00% | +3,500 | New |
| Lighthouse Investment Partners, LLC | 3,500 | $1.60M | 0.06% | +3,500 | New |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 3,500 | $1.60M | 0.00% | +3,500 | New |
| Summit Trail Advisors, LLC | 3,435 | $1.57M | 0.02% | +626+22.3% | Added |
| Spectrum Planning & Advisory Services Inc. | 3,350 | $1.53M | 0.86% | −9−0.3% | Reduced |
| Oxford Asset Management LLP | 3,350 | $1.53M | 0.50% | +882+35.7% | Added |
| Kentucky Retirement Systems Insurance Trust Fund | 3,285 | $1.50M | 0.10% | −218−6.2% | Reduced |
| Sectoral Asset Management Inc | 3,273 | $1.49M | 0.92% | −50−1.5% | Reduced |
| Hall Laurie J Trustee | 3,250 | $1.48M | 0.48% | 00.0% | Unchanged |
| Generali Asset Management SPA SGR | 3,234 | $1.47M | 0.03% | +3,184+6,368.0% | Added |
| Kennedy Capital Management, Inc. | 3,220 | $1.47M | 0.03% | +1,552+93.0% | Added |
| Cambridge Investment Research Advisors, Inc. | 3,180 | $1.45M | 0.00% | +1,796+129.8% | Added |
| Sumitomo Life Insurance Co | 3,167 | $1.44M | 0.04% | +1,049+49.5% | Added |
| Sanders Morris Harris LLC | 3,150 | $1.44M | 0.19% | +3,150 | New |
| Orion Capital Management LLC | 3,140 | $1.43M | 0.50% | −100−3.1% | Reduced |
| Grandfield & Dodd, LLC | 3,120 | $1.42M | 0.08% | +68+2.2% | Added |
| Graham Capital Management, L.P. | 3,015 | $1.37M | 0.05% | −135−4.3% | Reduced |
| Everence Capital Management Inc | 2,970 | $1.35M | 0.08% | 00.0% | Unchanged |
| Generali Investments CEE, investicni spolecnost, a.s. | 2,900 | $1.32M | 0.10% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 2,827 | $1.29M | 0.02% | −9,262−76.6% | Reduced |
| Fig Financial Advisory Services Inc | 2,812 | $1.28M | 0.80% | +2,812 | New |
| GF Fund Management Co. Ltd. | 2,797 | $1.28M | 0.02% | −505−15.3% | Reduced |
| Vontobel Holding Ltd. | 2,782 | $1.27M | 0.00% | −135−4.6% | Reduced |
| Shell Asset Management Co | 2,779 | $1.27M | 0.13% | −4,478−61.7% | Reduced |
| RSM US Wealth Management LLC | 2,764 | $1.26M | 0.02% | −1,639−37.2% | Reduced |
| Callan Family Office, LLC | 2,756 | $1.26M | 0.04% | −175−6.0% | Reduced |
| Wiley Bros.-Aintree Capital, LLC | 2,743 | $1.25M | 0.01% | +1,213+79.3% | Added |