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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
823
+178 vs. Q2 2025
Shares held
129.9M
−193.8K (−0.1%) vs. Q2 2025
Total value
$59.2B
+$16.8B (+39.6%) vs. Q2 2025
New holders
225
283 more added
Sold out
47
223 more reduced

8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 823 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ3 2025: $59.2B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.

Institutions holding ALNY in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Shepherd Financial Partners LLC2,736$1.25M0.12%00.0%Unchanged
Greenleaf Trust2,735$1.25M0.01%+5+0.2%Added
Park Avenue Securities LLC2,731$1.25M0.01%+646+31.0%Added
Western Financial Corp2,724$1.24M0.54%+2,724New
FORA Capital, LLC2,719$1.24M0.22%+2,719New
Regal Investment Advisors LLC2,702$1.23M0.08%−204−7.0%Reduced
Central Pacific Bank - Trust Division2,635$1.20M0.15%−383−12.7%Reduced
Everhart Financial Group, Inc.2,630$1.20M0.12%+437+19.9%Added
Y-Intercept (Hong Kong) Ltd2,614$1.19M0.03%+2,614New
Kovitz Investment Group Partners, LLC2,607$1.19M0.00%+257+10.9%Added
NEOS Investment Management LLC2,563$1.17M0.01%−2,738−51.7%Reduced
Tema ETFs LLC2,563$1.17M0.10%−2,738−51.7%Reduced
Vestcor Inc2,527$1.15M0.03%−309−10.9%Reduced
Horizon Kinetics Asset Management LLC2,480$1.13M0.01%−279−10.1%Reduced
Principal Securities, Inc.2,438$1.11M0.02%+724+42.2%Added
QRG Capital Management, Inc.2,435$1.11M0.01%+299+14.0%Added
Nixon Peabody Trust Co2,347$1.07M0.08%+10+0.4%Added
Persistent Asset Partners Ltd2,252$1.03M0.74%+2,252New
Anchor Investment Management, LLC2,249$1.03M0.08%+2,049+1,024.5%Added
UniSuper Management Pty Ltd2,200$1.00M0.01%00.0%Unchanged
Ethic Inc.2,184$996.0K0.02%+8+0.4%Added
United Capital Financial Advisers, LLC2,145$978.1K0.01%+570+36.2%Added
Aristeia Capital LLC2,100$957.6K0.03%+2,100New
Whitebox Advisors LLC2,100$957.6K0.02%+2,100New
Exchange Traded Concepts, LLC2,073$945.3K0.01%−733−26.1%Reduced
Pinkerton Retirement Specialists, LLC2,049$934.3K0.10%+2,049New
Bannerman Wealth Management Group, LLC2,047$933.4K0.69%−117−5.4%Reduced
Archford Capital Strategies, LLC2,024$922.9K0.11%+7+0.3%Added
Harvest Fund Management Co., Ltd2,021$920.0K0.04%+896+79.6%Added
CSS LLC2,010$916.6K0.05%+2,010New
Security National Bank of So Dak2,000$912.0K0.46%00.0%Unchanged
Signaturefd, LLC1,998$911.2K0.01%+92+4.8%Added
Fred Alger Management, LLC1,986$905.6K0.00%+1,986New
Greenland Capital Management LP1,959$893.3K0.13%+959+95.9%Added
Meeder Advisory Services, Inc.1,889$861.4K0.04%+764+67.9%Added
Siemens Fonds Invest GmbH1,837$837.7K0.05%−6−0.3%Reduced
Financiere des Professionnels - Fonds d,investissement inc.1,804$822.6K0.05%+1,804New
Two Sigma Securities, LLC1,740$793.4K0.12%+1,740New
Nomura Holdings Inc1,726$787.1K0.00%+1,726New
Oppenheimer & Co Inc1,716$782.5K0.01%00.0%Unchanged
Fort Sheridan Advisors LLC1,701$775.7K0.10%00.0%Unchanged
Emerald Advisers, LLC1,695$772.9K0.02%−246−12.7%Reduced
Caerus Investment Advisors, LLC1,672$762.4K0.31%+1,672New
Ballentine Partners, LLC1,661$757.4K0.01%+44+2.7%Added
R Squared Ltd1,660$757.0K0.33%+1,660New
Yousif Capital Management, LLC1,647$751.0K0.01%+80+5.1%Added
iA Global Asset Management Inc.1,647$751.0K0.01%+1,647New
Kestra Advisory Services, LLC1,645$750.1K0.00%+561+51.8%Added
Sava Infond d.o.o.1,640$747.8K0.11%−540−24.8%Reduced
Coldstream Capital Management Inc1,640$747.8K0.01%+38+2.4%Added
GraniteShares Advisors LLC1,639$747.4K0.43%−260−13.7%Reduced
Steel Peak Wealth Management LLC1,635$745.4K0.03%−1,173−41.8%Reduced
New York Life Investment Management LLC1,629$742.8K0.01%−474−22.5%Reduced
NorthCrest Asset Manangement, LLC1,605$737.5K0.02%+1,605New
Walleye Trading LLC1,595$727.3K0.01%+1,252+365.0%Added
S-Bank Fund Management Ltd1,593$726.4K0.10%−21−1.3%Reduced
Diversified Trust Co1,570$715.9K0.01%+472+43.0%Added
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,533$711.3K0.01%00.0%Unchanged
Forum Financial Management, LP1,556$709.5K0.01%00.0%Unchanged
Ossiam1,556$709.5K0.01%+201+14.8%Added
Fulton Bank, N.A.1,544$704.1K0.02%+123+8.7%Added
Orser Capital Management, LLC1,544$704.1K0.39%+1,544New
Tower Research Capital LLC (TRC)1,537$700.9K0.02%+1,473+2,301.6%Added
GWM Advisors LLC1,524$694.7K0.00%+820+116.5%Added
High Net Worth Advisory Group LLC1,500$684.0K0.16%00.0%Unchanged
CTC Alternative Strategies, Ltd.1,496$682.2K1.14%+1,496New
HB Wealth Management, LLC1,476$673.1K0.00%+607+69.9%Added
Point72 Asia (Singapore) Pte. Ltd.1,474$672.6K0.10%+656+80.2%Added
Qtron Investments LLC1,471$670.8K0.08%+1,471New
Fox Run Management, L.L.C.1,465$668.0K0.10%+202+16.0%Added
Virtus Investment Advisers, Inc.1,459$665.3K0.19%00.0%Unchanged
Sara-Bay Financial1,450$661.2K0.18%00.0%Unchanged
Steward Partners Investment Advisory, LLC1,443$658.0K0.00%+86+6.3%Added
Souders Financial Advisors1,423$648.9K0.08%+64+4.7%Added
Private Advisory Group LLC1,419$647.1K0.06%+1,419New
Lecap Asset Management Ltd1,418$646.6K0.22%−567−28.6%Reduced
Freestone Grove Partners LP1,412$643.9K0.00%+1,412New
Norden Group LLC1,411$643.4K0.07%+1,411New
J.Safra Asset Management Corp1,395$636.1K0.04%+1,352+3,144.2%Added
Banque Pictet & Cie SA1,385$631.6K0.01%−6−0.4%Reduced
Westpac Banking Corp1,355$617.9K0.04%00.0%Unchanged
Cubist Systematic Strategies, LLC1,352$616.4K0.01%+1,352New
Winslow Capital Management, LLC1,335$608.8K0.00%−1,176,104−99.9%Reduced
Envestnet Portfolio Solutions, Inc.1,327$605.1K0.00%+163+14.0%Added
Abn Amro Investment Solutions1,310$597.4K0.01%00.0%Unchanged
Convergence Investment Partners, LLC1,307$596.0K0.13%−952−42.1%Reduced
North Star Asset Management Inc1,305$595.1K0.02%00.0%Unchanged
Quantedge Capital Pte Ltd1,300$592.8K0.32%+1,300New
Allworth Financial LP1,290$588.1K0.00%+599+86.7%Added
Sagespring Wealth Partners, LLC1,287$587.0K0.01%+371+40.5%Added
Wetherby Asset Management Inc1,266$577.3K0.02%+40+3.3%Added
Qsemble Capital Management, LP1,255$572.3K0.06%−275−18.0%Reduced
Frank, Rimerman Advisors LLC1,251$570.5K0.04%+24+2.0%Added
Crowley Wealth Management, Inc.1,250$570.0K0.45%00.0%Unchanged
DeepCurrents Investment Group LLC1,243$566.8K0.02%+1,243New
Essential Partners LLC1,236$563.6K0.19%+1,174+1,893.5%Added
Vinva Investment Management Ltd1,258$562.9K0.01%+1,258New
Semanteon Capital Management, LP1,232$561.8K0.70%+1,232New
HBK Investments L P1,231$561.3K0.01%+1,231New
Capstone Investment Advisors, LLC1,231$561.3K0.00%+1,231New