Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 852
- +55 vs. Q3 2025
- Shares held
- 132.8M
- +3.06M (+2.4%) vs. Q3 2025
- Total value
- $52.7B
- −$6.43B (−10.9%) vs. Q3 2025
- New holders
- 172
- 290 more added
- Sold out
- 117
- 291 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Grandfield & Dodd, LLC | 3,129 | $1.24M | 0.07% | +9+0.3% | Added |
| Polymer Capital Management (US) LLC | 3,070 | $1.22M | 0.16% | +2,262+280.0% | Added |
| Cambridge Investment Research Advisors, Inc. | 3,032 | $1.21M | 0.00% | −148−4.7% | Reduced |
| Balyasny Asset Management LLC | 3,026 | $1.20M | 0.00% | −7,234−70.5% | Reduced |
| GWM Advisors LLC | 3,017 | $1.20M | 0.00% | +1,493+98.0% | Added |
| Sivik Global Healthcare LLC | 3,000 | $1.19M | 0.58% | +3,000 | New |
| Sectoral Asset Management Inc | 2,990 | $1.19M | 0.95% | −283−8.6% | Reduced |
| Everence Capital Management Inc | 2,970 | $1.18M | 0.07% | 00.0% | Unchanged |
| Orion Capital Management LLC | 2,967 | $1.18M | 0.40% | −173−5.5% | Reduced |
| Virtu Financial LLC | 2,941 | $1.17M | 0.05% | −8,715−74.8% | Reduced |
| Generali Investments CEE, investicni spolecnost, a.s. | 2,900 | $1.15M | 0.08% | 00.0% | Unchanged |
| Fig Financial Advisory Services Inc | 2,845 | $1.13M | 0.72% | +33+1.2% | Added |
| Hall Laurie J Trustee | 2,812 | $1.12M | 0.37% | −438−13.5% | Reduced |
| Robertson Stephens Wealth Management, LLC | 2,800 | $1.11M | 0.03% | +2,800 | New |
| Shepherd Financial Partners LLC | 2,736 | $1.09M | 0.10% | 00.0% | Unchanged |
| Greenleaf Trust | 2,733 | $1.09M | 0.01% | −2−0.1% | Reduced |
| Western Financial Corp | 2,731 | $1.09M | 0.43% | +7+0.3% | Added |
| Regal Investment Advisors LLC | 2,714 | $1.08M | 0.06% | +12+0.4% | Added |
| Wiley Bros.-Aintree Capital, LLC | 2,697 | $1.07M | 0.01% | −46−1.7% | Reduced |
| Anchor Investment Management, LLC | 2,695 | $1.07M | 0.09% | +446+19.8% | Added |
| Financiere des Professionnels - Fonds d,investissement inc. | 2,689 | $1.07M | 0.06% | +885+49.1% | Added |
| Mitsubishi UFJ Morgan Stanley Securities Co., Ltd. | 2,682 | $1.07M | 1.68% | +2,682 | New |
| RMB Capital Management, LLC | 2,662 | $1.06M | 0.02% | +2,662 | New |
| Principal Securities, Inc. | 2,626 | $1.04M | 0.02% | +188+7.7% | Added |
| RSM US Wealth Management LLC | 2,575 | $1.02M | 0.01% | −189−6.8% | Reduced |
| Everhart Financial Group, Inc. | 2,541 | $1.01M | 0.09% | −89−3.4% | Reduced |
| Oxford Asset Management LLP | 2,534 | $1.01M | 0.36% | −816−24.4% | Reduced |
| UniSuper Management Pty Ltd | 2,500 | $994.1K | 0.01% | +300+13.6% | Added |
| Theory Financial LLC | 2,744 | $991.5K | 0.33% | +2,744 | New |
| Portman Square Capital LLP | 2,457 | $977.0K | 0.17% | +2,457 | New |
| United Capital Financial Advisers, LLC | 2,449 | $973.9K | 0.01% | +304+14.2% | Added |
| ING Groep NV | 2,444 | $971.9K | 0.01% | +2,444 | New |
| Draper Asset Management, LLC | 2,422 | $963.1K | 0.51% | +1,680+226.4% | Added |
| Inceptionr LLC | 2,415 | $960.3K | 0.27% | −1,104−31.4% | Reduced |
| Central Pacific Bank - Trust Division | 2,413 | $959.5K | 0.12% | −222−8.4% | Reduced |
| Park Avenue Securities LLC | 2,391 | $951.0K | 0.01% | −340−12.4% | Reduced |
| Horizon Kinetics Asset Management LLC | 2,376 | $944.8K | 0.01% | −104−4.2% | Reduced |
| QRG Capital Management, Inc. | 2,363 | $939.5K | 0.01% | −72−3.0% | Reduced |
| Exchange Traded Concepts, LLC | 2,361 | $938.9K | 0.01% | +288+13.9% | Added |
| Nixon Peabody Trust Co | 2,337 | $929.3K | 0.07% | −10−0.4% | Reduced |
| Vontobel Holding Ltd. | 2,319 | $922.2K | 0.00% | −463−16.6% | Reduced |
| Capstone Capital Management Ltd | 2,301 | $915.0K | 0.88% | +2,301 | New |
| Twin Capital Management Inc | 2,208 | $878.0K | 0.11% | +2,208 | New |
| Private Advisory Group LLC | 2,155 | $856.9K | 0.07% | +736+51.9% | Added |
| ICICI Prudential Asset Management Co Ltd | 2,120 | $843.0K | 0.10% | +2,120 | New |
| Alpine Global Management, LLC | 2,062 | $820.0K | 0.18% | +2,062 | New |
| DRW Securities, LLC | 2,041 | $811.6K | 0.06% | +2,041 | New |
| Archford Capital Strategies, LLC | 2,024 | $804.8K | 0.09% | 00.0% | Unchanged |
| Elm Partners Management LLC | 2,008 | $798.5K | 0.04% | +2,008 | New |
| Security National Bank of So Dak | 2,000 | $795.3K | 0.39% | 00.0% | Unchanged |
| TCW Group Inc | 2,000 | $795.3K | 0.01% | +2,000 | New |
| Sivia Capital Partners, LLC | 1,997 | $794.1K | 0.16% | +901+82.2% | Added |
| Tema ETFs LLC | 1,996 | $793.7K | 0.06% | −567−22.1% | Reduced |
| Signaturefd, LLC | 1,981 | $787.9K | 0.01% | −17−0.9% | Reduced |
| V-Square Quantitative Management LLC | 1,958 | $778.6K | 0.08% | +1,958 | New |
| Kovitz Investment Group Partners, LLC | 1,955 | $777.6K | 0.02% | −652−25.0% | Reduced |
| Bannerman Wealth Management Group, LLC | 1,947 | $774.2K | 0.55% | −100−4.9% | Reduced |
| Quest Partners LLC | 1,881 | $748.0K | 0.04% | +1,550+468.3% | Added |
| XTX Topco Ltd | 1,856 | $738.0K | 0.02% | +1,022+122.5% | Added |
| Global Retirement Partners, LLC | 1,856 | $738.0K | 0.01% | +1,407+313.4% | Added |
| AlphaGrep UK Ltd | 1,856 | $738.0K | 0.25% | +1,856 | New |
| Kestra Advisory Services, LLC | 1,851 | $736.0K | 0.00% | +206+12.5% | Added |
| Meeder Advisory Services, Inc. | 1,838 | $730.9K | 0.03% | −51−2.7% | Reduced |
| Siemens Fonds Invest GmbH | 1,837 | $729.7K | 0.04% | 00.0% | Unchanged |
| GraniteShares Advisors LLC | 1,786 | $710.2K | 0.43% | +147+9.0% | Added |
| Ossiam | 1,786 | $710.2K | 0.01% | +230+14.8% | Added |
| Evolve Private Wealth, LLC | 1,783 | $709.0K | 0.04% | +1,783 | New |
| Woodline Partners LP | 1,759 | $699.5K | 0.00% | −90,032−98.1% | Reduced |
| Davenport & Co LLC | 1,759 | $699.5K | 0.00% | +1,759 | New |
| Sara-Bay Financial | 1,750 | $695.2K | 0.21% | +300+20.7% | Added |
| New York Life Investment Management LLC | 1,745 | $693.9K | 0.01% | +116+7.1% | Added |
| NorthCrest Asset Manangement, LLC | 1,733 | $689.4K | 0.02% | +128+8.0% | Added |
| Ballentine Partners, LLC | 1,721 | $684.4K | 0.01% | +60+3.6% | Added |
| Virtus Investment Advisers, Inc. | 1,717 | $682.8K | 0.19% | +258+17.7% | Added |
| HB Wealth Management, LLC | 1,701 | $676.7K | 0.00% | +225+15.2% | Added |
| Fort Sheridan Advisors LLC | 1,701 | $676.4K | 0.09% | 00.0% | Unchanged |
| J.Safra Asset Management Corp | 1,639 | $651.7K | 0.03% | +244+17.5% | Added |
| Emerald Advisers, LLC | 1,622 | $645.0K | 0.02% | −73−4.3% | Reduced |
| Coldstream Capital Management Inc | 1,574 | $625.9K | 0.01% | −66−4.0% | Reduced |
| Diversified Trust Co | 1,548 | $615.6K | 0.01% | −22−1.4% | Reduced |
| Forum Financial Management, LP | 1,546 | $614.8K | 0.01% | −10−0.6% | Reduced |
| Orser Capital Management, LLC | 1,539 | $612.0K | 0.37% | −5−0.3% | Reduced |
| EntryPoint Capital, LLC | 1,527 | $607.2K | 0.24% | +469+44.3% | Added |
| Vise Technologies, Inc. | 1,515 | $602.4K | 0.01% | +491+47.9% | Added |
| High Net Worth Advisory Group LLC | 1,500 | $596.5K | 0.14% | 00.0% | Unchanged |
| Yousif Capital Management, LLC | 1,676 | $595.9K | 0.01% | +29+1.8% | Added |
| Steel Peak Wealth Management LLC | 1,484 | $590.0K | 0.02% | −151−9.2% | Reduced |
| Qtron Investments LLC | 1,471 | $584.9K | 0.08% | 00.0% | Unchanged |
| Summit Financial, LLC | 1,456 | $579.0K | 0.01% | +1,456 | New |
| 111 Capital | 1,451 | $577.0K | 0.13% | +1,451 | New |
| Krilogy Financial LLC | 1,587 | $573.5K | 0.02% | −2,235−58.5% | Reduced |
| Persistent Asset Partners Ltd | 1,433 | $569.8K | 0.27% | −819−36.4% | Reduced |
| Fulton Bank, N.A. | 1,430 | $568.6K | 0.02% | −114−7.4% | Reduced |
| Steward Partners Investment Advisory, LLC | 1,425 | $566.7K | 0.00% | −18−1.2% | Reduced |
| Souders Financial Advisors | 1,410 | $560.7K | 0.06% | −13−0.9% | Reduced |
| Altfest L J & Co Inc | 1,378 | $548.0K | 0.06% | +1,378 | New |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 1,533 | $543.8K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 1,353 | $538.1K | 0.00% | +63+4.9% | Added |
| Headlands Technologies LLC | 1,345 | $534.8K | 0.04% | −8,847−86.8% | Reduced |
| PSP Research LLC | 1,318 | $524.1K | 0.46% | +1,318 | New |