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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
852
+55 vs. Q3 2025
Shares held
132.8M
+3.06M (+2.4%) vs. Q3 2025
Total value
$52.7B
−$6.43B (−10.9%) vs. Q3 2025
New holders
172
290 more added
Sold out
117
291 more reduced

26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 852 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2025: $52.7B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding ALNY in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Bare Financial Services, Inc1$3980.00%−2−66.7%Reduced
Davis Capital Management1$3980.00%00.0%Unchanged
Seneschal Advisors, LLC1$3980.00%00.0%Unchanged
ROSS\JOHNSON & Associates LLC1$3980.01%00.0%Unchanged
Chilton Capital Management LLC1$3980.00%+1New
Hollencrest Capital Management1$3980.00%+1New
Financial Consulate, Inc1$3980.00%+1New
Atlantic Private Wealth, LLC1$3980.00%+1New
Glen Eagle Advisors, LLC1$3980.00%+1New
Central Trust Co1$5530.00%00.0%Unchanged
Creative Financial Designs Inc2$7950.00%00.0%Unchanged
Battery Global Advisors, LLC2$7950.00%+2New
Retirement Wealth Solutions LLC2$7960.00%−3−60.0%Reduced
Quaker Wealth Management, LLC2$7960.00%00.0%Unchanged
Breakwater Investment Management2$7960.00%00.0%Unchanged
Acumen Wealth Advisors, LLC2$7960.00%+2New
PEAK6 LLC2$8660.00%−1−33.3%Reduced
Ogorek Anthony Joseph3$1.00K0.00%00.0%Unchanged
Investors Portfolio Services LLC3$1.13K0.00%+3New
Wealth Watch Advisors, INC3$1.19K0.00%−6−66.7%Reduced
TD Private Client Wealth LLC3$1.19K0.00%00.0%Unchanged
Rialto Wealth Management, LLC3$1.19K0.00%00.0%Unchanged
DV Trading LLC3$1.19K0.00%+3New
First Command Advisory Services, Inc.3$1.19K0.00%+3New
Independence Bank of Kentucky3$1.19K0.00%+3New
Rosenberg Matthew Hamilton3$1.19K0.00%+3New
1015 Capital Partners, LLC3$1.19K0.00%+3New
Kayne Anderson Rudnick Investment Management LLC3$1.44K0.00%+1+50.0%Added
Beaird Harris Wealth Management, LLC4$1.59K0.00%00.0%Unchanged
American Capital Advisory, LLC4$1.59K0.00%00.0%Unchanged
Greykasell Wealth Strategies, Inc.4$1.59K0.00%00.0%Unchanged
JNBA Financial Advisors4$1.59K0.00%+4New
Jessup Wealth Management, Inc4$1.59K0.00%+4New
United Financial Planning Group LLC4$1.59K0.00%+4New
Purpose Unlimited Inc.4$1.59K0.00%+4New
Winnow Wealth LLC4$1.59K0.00%−3−42.9%Reduced
Abound Wealth Management4$1.73K0.00%00.0%Unchanged
Montag A & Associates Inc5$1.86K0.00%−1−16.7%Reduced
CBIZ Investment Advisory Services, LLC5$1.99K0.00%00.0%Unchanged
High Note Wealth, LLC5$1.99K0.00%+5New
Dunhill Financial, LLC5$1.99K0.00%+5New
Lodestone Wealth Management LLC5$1.99K0.00%+5New
Nemes Rush Group LLC5$1.99K0.00%+5New
Optima Capital LLC5$1.99K0.00%+5New
Asset Dedication, LLC5$1.99K0.00%00.0%Unchanged
CX Institutional5$2.00K0.00%+5New
Winthrop Capital Management, LLC4$2.00K0.00%+4New
AdvisorNet Financial, Inc6$2.39K0.00%−15−71.4%Reduced
Principia Wealth Advisory, LLC6$2.39K0.00%+1+20.0%Added
American National Bank6$2.39K0.00%+6New
Steigerwald, Gordon & Koch Inc.6$2.39K0.00%+6New
ZRC Wealth Management, LLC6$2.39K0.00%+6New
Signature Equity Partners, LLC6$2.39K0.00%+6New
City Holding Co7$2.78K0.00%00.0%Unchanged
Johnson Financial Group, Inc.7$2.78K0.00%−5−41.7%Reduced
Front Row Advisors LLC7$2.78K0.00%00.0%Unchanged
Penserra Capital Management LLC9$3.00K0.00%00.0%Unchanged
Motiv8 Investments LLC7$3.00K0.00%+7New
NBC Securities, Inc.8$3.18K0.00%−4−33.3%Reduced
Highline Wealth Partners LLC8$3.18K0.00%00.0%Unchanged
Signature Resources Capital Management, LLC8$3.18K0.00%+8New
DiNuzzo Private Wealth, Inc.8$3.18K0.00%00.0%Unchanged
First Pacific Financial8$3.18K0.00%+8New
Washington Trust Advisors, Inc.9$3.42K0.00%+1+12.5%Added
Bay Harbor Wealth Management, LLC9$3.58K0.00%+3+50.0%Added
Ameriflex Group, Inc.9$3.58K0.00%−61−87.1%Reduced
Grove Bank & Trust9$3.58K0.00%+9New
Mark Sheptoff Financial Planning, LLC10$3.98K0.00%00.0%Unchanged
Archer Investment Corp10$3.98K0.00%00.0%Unchanged
Tripletail Wealth Management, LLC10$3.98K0.01%00.0%Unchanged
Toth Financial Advisory Corp10$3.98K0.00%+1+11.1%Added
HFM Investment Advisors, LLC10$3.98K0.00%+9+900.0%Added
High Point Wealth Management, LLC10$3.98K0.00%+10New
Curio Wealth, LLC10$4.01K0.00%+10New
S&T Bank11$4.37K0.00%−4−26.7%Reduced
Flagship Harbor Advisors, LLC11$4.37K0.00%+11New
Accent Capital Management, LLC12$4.77K0.00%00.0%Unchanged
Hughes Financial Services, LLC12$4.77K0.00%00.0%Unchanged
Valley National Advisers Inc13$5.00K0.00%−2−13.3%Reduced
Motco13$5.17K0.00%00.0%Unchanged
Chung Wu Investment Group, LLC13$5.17K0.00%00.0%Unchanged
Cornerstone Financial Management LLC13$5.17K0.00%+13New
Trust Co of Vermont14$5.57K0.00%00.0%Unchanged
Umb Bank N A14$5.57K0.00%+2+16.7%Added
HighMark Wealth Management LLC14$5.57K0.00%+14New
South State Corp.14$5.57K0.00%−6−30.0%Reduced
Sunbelt Securities, Inc.15$5.96K0.00%00.0%Unchanged
Sherman Asset Management, Inc.15$5.96K0.01%00.0%Unchanged
Strategic Wealth Partners, Ltd.15$5.96K0.00%+15New
Fourth Dimension Wealth, LLC16$6.36K0.00%−557−97.2%Reduced
Vermillion & White Wealth Management Group, LLC16$6.36K0.00%00.0%Unchanged
Cetera Trust Company, N.A16$6.36K0.00%00.0%Unchanged
Wilkerson Advisory Group LLC17$6.76K0.00%+17New
Raffa Wealth Management, LLC18$7.16K0.00%+3+20.0%Added
Osbon Capital Management LLC18$7.16K0.01%+18New
Elyxium Wealth, LLC18$7.16K0.00%+18New
TCTC Holdings, LLC19$7.55K0.00%00.0%Unchanged
Cromwell Holdings LLC20$7.95K0.00%00.0%Unchanged
Ares Financial Consulting, LLC20$7.95K0.01%+20New
Ancora Advisors, LLC22$8.75K0.00%+22New