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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
852
+55 vs. Q3 2025
Shares held
132.8M
+3.06M (+2.4%) vs. Q3 2025
Total value
$52.7B
−$6.43B (−10.9%) vs. Q3 2025
New holders
172
290 more added
Sold out
117
291 more reduced

26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 852 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2025: $52.7B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding ALNY in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Wealthcare Advisory Partners LLC1,311$521.3K0.01%+1,311New
AlphaCentric Advisors LLC1,295$515.0K0.51%+1,295New
Sava Infond d.o.o.1,285$511.0K0.07%−355−21.6%Reduced
S-Bank Fund Management Ltd1,281$509.4K0.07%−312−19.6%Reduced
Crossmark Global Holdings, Inc.1,281$509.4K0.01%+57+4.7%Added
Winslow Capital Management, LLC1,266$503.4K0.00%−69−5.2%Reduced
Frank, Rimerman Advisors LLC1,250$497.1K0.03%−1−0.1%Reduced
Pinnacle Financial Partners, Inc.1,237$491.9K0.00%+1,237New
Farther Finance Advisors, LLC1,235$491.0K0.01%+507+69.6%Added
Cigna Investments Inc1,230$490.0K0.07%00.0%Unchanged
Bridges Investment Management Inc1,216$483.5K0.01%+422+53.1%Added
Smartleaf Asset Management LLC1,203$477.9K0.02%+126+11.7%Added
Norden Group LLC1,190$473.2K0.05%−221−15.7%Reduced
Wedmont Private Capital1,113$470.2K0.02%+58+5.5%Added
Caerus Investment Advisors, LLC1,173$466.4K0.16%−499−29.8%Reduced
Mathes Company, Inc.1,155$459.0K0.16%00.0%Unchanged
Lecap Asset Management Ltd1,151$457.7K0.18%−267−18.8%Reduced
Hilltop Holdings Inc.1,139$452.9K0.03%−50−4.2%Reduced
Sagespring Wealth Partners, LLC1,136$451.8K0.01%−151−11.7%Reduced
Flow Traders U.S. LLC1,135$451.0K0.01%+1,135New
TB Alternative Assets Ltd.1,133$450.5K0.07%00.0%Unchanged
Banque Pictet & Cie SA1,120$445.4K0.00%−265−19.1%Reduced
Abel Hall, LLC1,111$441.8K0.10%+1,111New
Simplify Asset Management Inc.1,109$441.0K0.01%+335+43.3%Added
North Star Asset Management Inc1,105$439.4K0.02%−200−15.3%Reduced
Capital Group Private Client Services, Inc.1,070$425.5K0.01%00.0%Unchanged
EverSource Wealth Advisors, LLC1,061$421.9K0.02%−69−6.1%Reduced
Sentinus, LLC1,051$417.9K0.04%+1,051New
Coastal Bridge Advisors, LLC1,048$416.7K0.03%−49−4.5%Reduced
Prosperity Consulting Group, LLC1,041$414.0K0.02%+1,041New
Nichols & Pratt Advisers LLP1,039$413.2K0.03%−4−0.4%Reduced
Elevate Capital Advisors, LLC1,039$413.2K0.27%+1,039New
Asahi Life Asset Management Co., Ltd.1,033$410.8K0.23%−10−1.0%Reduced
Waddell & Associates, LLC1,017$404.4K0.03%−1−0.1%Reduced
Breakwater Capital Group1,007$400.4K0.06%−20−1.9%Reduced
Parcion Private Wealth LLC1,002$398.4K0.02%+213+27.0%Added
Calamos Advisors LLC1,000$397.6K0.00%−200−16.7%Reduced
Westmount Partners, LLC1,000$397.6K0.10%00.0%Unchanged
Livforsakringsbolaget Skandia, Omsesidigt1,000$397.6K0.02%00.0%Unchanged
CAPROCK Group, Inc.992$394.5K0.01%+135+15.8%Added
Oppenheimer & Co Inc966$384.1K0.01%−750−43.7%Reduced
Generali Investments, Management Co LLC965$383.7K0.08%+965New
Optimist Retirement Group LLC962$382.5K0.18%+962New
Cynosure Management, LLC950$377.8K0.04%+950New
Ostrum Asset Management947$376.6K0.02%+566+148.6%Added
Aaron Wealth Advisors932$370.6K0.02%−177−16.0%Reduced
Picton Mahoney Asset Management932$370.6K0.00%+932New
Prelude Capital Management, LLC928$369.0K0.03%+928New
Thayer Partners, LLC927$368.6K0.18%+927New
HCR Wealth Advisors924$367.4K0.04%00.0%Unchanged
denkapparat Operations GmbH912$362.7K0.20%+912New
Atomi Financial Group, Inc.907$360.8K0.01%−35−3.7%Reduced
waypoint wealth counsel895$355.9K0.13%+274+44.1%Added
GAMMA Investing LLC893$355.1K0.02%+70+8.5%Added
Beese Fulmer Investment Management, Inc.888$353.1K0.02%+888New
Savant Capital, LLC875$347.9K0.00%−8−0.9%Reduced
Ellevest, Inc.863$343.2K0.05%+89+11.5%Added
Jackson Thornton Asset Management, LLC842$342.2K0.03%−76−8.3%Reduced
Poinciana Advisors Group, LLC851$338.4K0.27%−6−0.7%Reduced
Stephens Inc845$336.0K0.00%+146+20.9%Added
Warren Averett Asset Management, LLC840$334.0K0.00%−25−2.9%Reduced
Snowden Capital Advisors LLC834$331.6K0.01%−33−3.8%Reduced
We Are One Seven, LLC833$331.2K0.01%+133+19.0%Added
HighPoint Advisor Group LLC832$330.8K0.01%+128+18.2%Added
Nwam LLC914$330.3K0.02%+2+0.2%Added
Parallel Advisors, LLC826$328.5K0.01%+30+3.8%Added
Chapin Davis, Inc.825$328.1K0.08%00.0%Unchanged
Cookson Peirce & Co Inc811$322.5K0.01%+264+48.3%Added
Concurrent Investment Advisors, LLC802$318.9K0.00%+802New
Ascent Group, LLC795$316.1K0.01%+171+27.4%Added
Blueshift Asset Management, LLC791$314.5K0.09%+188+31.2%Added
Beacon Pointe Advisors, LLC790$314.1K0.00%−164−17.2%Reduced
Lido Advisors, LLC717$311.9K0.00%+59+9.0%Added
Jones Financial Companies LLLP780$310.2K0.00%+238+43.9%Added
Perigon Wealth Management, LLC776$308.6K0.01%−407−34.4%Reduced
Wick Capital Partners, LLC769$305.8K0.05%+769New
SkyOak Wealth, LLC760$302.2K0.05%−87−10.3%Reduced
Kaufman Rossin Wealth, LLC749$297.7K0.16%+266+55.1%Added
Benjamin Edwards Inc733$291.4K0.00%+246+50.5%Added
Banco Santander, S.A.731$290.7K0.00%+731New
Sym Financial Corp729$289.9K0.03%+54+8.0%Added
Meridian Financial, LLC728$289.5K0.16%−100−12.1%Reduced
Perfromance Wealth Partners, LLC725$288.3K0.01%00.0%Unchanged
Ofi Invest Asset Management776$281.4K0.00%+373+92.6%Added
Bradley Foster & Sargent Inc701$278.8K0.00%+81+13.1%Added
Independent Financial Group, LLC698$277.6K0.01%+66+10.4%Added
GenTrust, LLC695$276.4K0.01%+695New
Essex Financial Services, Inc.690$274.2K0.02%−24−3.4%Reduced
Dynasty Wealth Management, LLC688$273.6K0.00%+20+3.0%Added
Ashton Thomas Securities, LLC688$273.6K0.05%+688New
Fiduciary Trust Co680$270.5K0.00%+7+1.0%Added
SRS Capital Advisors, Inc.678$269.6K0.01%−12,407−94.8%Reduced
Scientech Research LLC676$268.8K0.17%−3,196−82.5%Reduced
Glenmede Trust Co NA675$268.4K0.00%+675New
Savvy Advisors, Inc.672$267.2K0.01%−38−5.4%Reduced
EP Wealth Advisors, LLC671$266.8K0.00%+671New
L2 Asset Management, LLC671$266.8K0.04%+60+9.8%Added
Legacy Wealth Asset Management, LLC668$265.6K0.07%−26−3.7%Reduced
IFP Advisors, Inc664$264.0K0.01%+173+35.2%Added
Skopos Labs, Inc.648$258.3K0.01%+648New