Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 852
- +55 vs. Q3 2025
- Shares held
- 132.8M
- +3.06M (+2.4%) vs. Q3 2025
- Total value
- $52.7B
- −$6.43B (−10.9%) vs. Q3 2025
- New holders
- 172
- 290 more added
- Sold out
- 117
- 291 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| USS Investment Management Ltd | 26,224 | $10.4M | 0.05% | −142−0.5% | Reduced |
| Varma Mutual Pension Insurance Co | 26,100 | $10.4M | 0.06% | +26,100 | New |
| Erste Asset Management GmbH | 26,010 | $10.4M | 0.09% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 25,999 | $10.3M | 0.03% | +10,503+67.8% | Added |
| Illinois Municipal Retirement Fund | 25,771 | $10.2M | 0.13% | −1,374−5.1% | Reduced |
| Quantinno Capital Management LP | 25,592 | $10.2M | 0.02% | +6,327+32.8% | Added |
| Assenagon Asset Management S.A. | 25,590 | $10.2M | 0.02% | −54,791−68.2% | Reduced |
| CWM, LLC | 25,475 | $10.1M | 0.03% | −3,812−13.0% | Reduced |
| Macquarie Group Ltd | 25,281 | $10.1M | 0.04% | −623,063−96.1% | Reduced |
| China Universal Asset Management Co., Ltd. | 25,267 | $10.0M | 0.77% | +2,480+10.9% | Added |
| Mizuho Markets Cayman LP | 24,958 | $9.92M | 0.50% | +24,958 | New |
| Brown Advisory Inc | 24,858 | $9.88M | 0.01% | −1,734−6.5% | Reduced |
| Cerity Partners LLC | 24,578 | $9.77M | 0.01% | −2,851−10.4% | Reduced |
| Eurizon Capital SGR S.p.A. | 24,410 | $9.71M | 0.03% | +24,410 | New |
| Creative Planning | 23,815 | $9.47M | 0.01% | +953+4.2% | Added |
| CI Private Wealth, LLC | 23,763 | $9.45M | 0.01% | −15,629−39.7% | Reduced |
| British Columbia Investment Management Corp | 23,220 | $9.23M | 0.05% | +4,481+23.9% | Added |
| Toronto Dominion Bank | 23,199 | $9.23M | 0.02% | +1,972+9.3% | Added |
| Swiss Life Asset Management Ltd | 22,472 | $8.94M | 0.05% | +951+4.4% | Added |
| Nomura Holdings Inc | 22,437 | $8.92M | 0.03% | +20,711+1,199.9% | Added |
| Banco Bilbao Vizcaya Argentaria, S.A. | 21,926 | $8.72M | 0.06% | −309−1.4% | Reduced |
| Credit Agricole S A | 21,540 | $8.57M | 0.02% | +9,173+74.2% | Added |
| Investment Management Corp of Ontario | 21,535 | $8.56M | 0.11% | −16,423−43.3% | Reduced |
| Acadian Asset Management LLC | 21,308 | $8.47M | 0.01% | +2,225+11.7% | Added |
| Avidity Partners Management LP | 21,000 | $8.35M | 2.41% | +21,000 | New |
| Capital Fund Management S.A. | 20,940 | $8.33M | 0.08% | +20,940 | New |
| Utah Retirement Systems | 20,725 | $8.24M | 0.08% | +126+0.6% | Added |
| Thrivent Financial for Lutherans | 20,641 | $8.21M | 0.01% | +20,641 | New |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 20,482 | $8.14M | 0.29% | +20,482 | New |
| Stifel Financial Corp | 20,427 | $8.12M | 0.01% | +132+0.7% | Added |
| Engineers Gate Manager LP | 20,199 | $8.03M | 0.10% | −23,650−53.9% | Reduced |
| AIA Group Ltd | 20,177 | $8.02M | 0.12% | −13,136−39.4% | Reduced |
| Teacher Retirement System of Texas | 20,035 | $7.97M | 0.03% | −13,607−40.4% | Reduced |
| Empowered Funds, LLC | 19,431 | $7.73M | 0.13% | +15,146+353.5% | Added |
| Police & Firemen's Retirement System of New Jersey | 19,295 | $7.67M | 0.06% | −798−4.0% | Reduced |
| Liontrust Investment Partners LLP | 18,387 | $7.31M | 0.11% | +6,731+57.7% | Added |
| Wealthfront Advisers LLC | 18,254 | $7.26M | 0.02% | +4,834+36.0% | Added |
| Silvant Capital Management LLC | 17,964 | $7.14M | 0.24% | +288+1.6% | Added |
| Vinva Investment Management Ltd | 17,961 | $7.14M | 0.09% | +16,703+1,327.7% | Added |
| iA Global Asset Management Inc. | 17,780 | $7.07M | 0.09% | +16,133+979.5% | Added |
| MML Investors Services, LLC | 17,650 | $7.02M | 0.02% | −2,028−10.3% | Reduced |
| Cetera Investment Advisers | 17,549 | $6.98M | 0.01% | +3,026+20.8% | Added |
| Elo Mutual Pension Insurance Co | 17,441 | $6.94M | 0.11% | −424−2.4% | Reduced |
| Artia Global Partners LP | 17,400 | $6.92M | 1.11% | −17,170−49.7% | Reduced |
| Prosight Management, LP | 17,109 | $6.80M | 1.41% | +17,109 | New |
| Entropy Technologies, LP | 16,097 | $6.40M | 0.35% | −1,084−6.3% | Reduced |
| Assetmark, Inc | 16,033 | $6.38M | 0.01% | +4,115+34.5% | Added |
| Sumitomo Mitsui DS Asset Management Company, Ltd | 15,869 | $6.31M | 0.05% | +43+0.3% | Added |
| Oppenheimer Asset Management Inc. | 15,592 | $6.20M | 0.08% | +11,292+262.6% | Added |
| Profund Advisors LLC | 15,589 | $6.20M | 0.19% | +12,053+340.9% | Added |
| Mutual of America Capital Management LLC | 15,466 | $6.15M | 0.06% | +159+1.0% | Added |
| Shelton Capital Management | 15,064 | $5.99M | 0.12% | +15,064 | New |
| MUFG Securities EMEA plc | 15,000 | $5.96M | 0.07% | +15,000 | New |
| BI Asset Management Fondsmaeglerselskab A/S | 14,869 | $5.91M | 0.05% | +8,164+121.8% | Added |
| Capital Group Investment Management Pte. Ltd. | 14,846 | $5.90M | 0.96% | −2,017−12.0% | Reduced |
| OP Asset Management Ltd | 14,770 | $5.87M | 0.07% | +384+2.7% | Added |
| Wealth Enhancement Advisory Services, LLC | 14,087 | $5.74M | 0.01% | −438−3.0% | Reduced |
| JustInvest LLC | 13,727 | $5.46M | 0.05% | −258−1.8% | Reduced |
| Prudential Financial Inc | 13,309 | $5.29M | 0.01% | +4,177+45.7% | Added |
| Captrust Financial Advisors | 13,255 | $5.27M | 0.01% | +5,586+72.8% | Added |
| Capula Management Ltd | 13,181 | $5.24M | 0.03% | +6,293+91.4% | Added |
| Nordea Investment Management AB | 12,855 | $5.12M | 0.00% | +374+3.0% | Added |
| Rakuten Investment Management, Inc. | 12,684 | $5.06M | 0.02% | −18,468−59.3% | Reduced |
| The PNC Financial Services Group, Inc. | 12,678 | $5.04M | 0.00% | −437−3.3% | Reduced |
| Alberta Investment Management Corp | 12,600 | $5.01M | 0.03% | +900+7.7% | Added |
| Federation des caisses Desjardins du Quebec | 12,549 | $4.99M | 0.02% | −2,078−14.2% | Reduced |
| Motley Fool Asset Management LLC | 12,526 | $4.98M | 0.19% | +3,480+38.5% | Added |
| Ilmarinen Mutual Pension Insurance Co | 12,500 | $4.97M | 0.04% | −8,500−40.5% | Reduced |
| Public Employees Retirement Association of Colorado | 12,445 | $4.95M | 0.02% | 00.0% | Unchanged |
| Mackenzie Financial Corp | 12,395 | $4.91M | 0.01% | +2,622+26.8% | Added |
| CIBC World Markets Inc. | 12,225 | $4.86M | 0.01% | +109+0.9% | Added |
| Zacks Investment Management | 12,008 | $4.77M | 0.04% | +104+0.9% | Added |
| Mercer Global Advisors Inc | 11,786 | $4.69M | 0.01% | +302+2.6% | Added |
| Traynor Capital Management, Inc. | 11,570 | $4.60M | 0.25% | +697+6.4% | Added |
| Raiffeisen Bank International AG | 11,506 | $4.57M | 0.06% | −103−0.9% | Reduced |
| Hantz Financial Services, Inc. | 11,323 | $4.50M | 0.07% | −1,823−13.9% | Reduced |
| Kornitzer Capital Management Inc | 11,114 | $4.42M | 0.09% | −12,575−53.1% | Reduced |
| Banque Cantonale Vaudoise | 11,037 | $4.39M | 0.16% | +6,177+127.1% | Added |
| Cullen/Frost Bankers, Inc. | 11,033 | $4.39M | 0.05% | −10−0.1% | Reduced |
| ASR Vermogensbeheer N.V. | 11,022 | $4.38M | 0.05% | +2,146+24.2% | Added |
| CIBC World Markets Corp | 10,965 | $4.36M | 0.02% | +10,965 | New |
| Amalgamated Bank | 10,679 | $4.25M | 0.03% | +535+5.3% | Added |
| Commerce Bank | 10,533 | $4.19M | 0.02% | +6,002+132.5% | Added |
| Silvercrest Asset Management Group LLC | 10,410 | $4.14M | 0.03% | −397−3.7% | Reduced |
| Atika Capital Management LLC | 10,339 | $4.11M | 0.57% | −11,867−53.4% | Reduced |
| Harvest Fund Management Co., Ltd | 10,319 | $4.10M | 0.15% | +8,298+410.6% | Added |
| Himension Fund | 10,185 | $4.05M | 0.25% | +91+0.9% | Added |
| Lazard Asset Management LLC | 10,152 | $4.04M | 0.01% | +401+4.1% | Added |
| O'Shaughnessy Asset Management, LLC | 9,927 | $3.95M | 0.02% | +619+6.7% | Added |
| Allstate Corp | 9,829 | $3.91M | 0.05% | +5,258+115.0% | Added |
| Employees Retirement System of Texas | 9,792 | $3.89M | 0.03% | 00.0% | Unchanged |
| Blair William & Co | 9,774 | $3.89M | 0.01% | −470−4.6% | Reduced |
| Commonwealth Equity Services, LLC | 9,745 | $3.87M | 0.01% | +338+3.6% | Added |
| Nisa Investment Advisors, LLC | 9,649 | $3.84M | 0.01% | −2,484−20.5% | Reduced |
| Pacer Advisors, Inc. | 9,588 | $3.81M | 0.01% | +9,588 | New |
| Campbell & CO Investment Adviser LLC | 9,490 | $3.77M | 0.18% | −3,207−25.3% | Reduced |
| J. Safra Sarasin Holding AG | 9,138 | $3.63M | 0.06% | −384−4.0% | Reduced |
| Martingale Asset Management L P | 9,124 | $3.63M | 0.09% | +9,124 | New |
| Capstone Investment Advisors, LLC | 8,918 | $3.55M | 0.03% | +7,687+624.5% | Added |
| Keystone Investors Pte Ltd | 8,880 | $3.53M | 0.32% | +8,880 | New |