Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 852
- +55 vs. Q3 2025
- Shares held
- 132.8M
- +3.06M (+2.4%) vs. Q3 2025
- Total value
- $52.7B
- −$6.43B (−10.9%) vs. Q3 2025
- New holders
- 172
- 290 more added
- Sold out
- 117
- 291 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 109,604 | $43.6M | 0.05% | +77,235+238.6% | Added |
| HighTower Advisors, LLC | 106,491 | $42.3M | 0.05% | −4,133−3.7% | Reduced |
| Pinebridge Investments LLC | 100,199 | $39.8M | 0.29% | +100,199 | New |
| Nomura Asset Management Co Ltd | 94,278 | $37.5M | 0.09% | +4,409+4.9% | Added |
| FIL Ltd | 94,164 | $37.4M | 0.03% | −41,320−30.5% | Reduced |
| Westfield Capital Management Co LP | 93,444 | $37.2M | 0.15% | +5,536+6.3% | Added |
| SG Americas Securities, LLC | 90,921 | $36.2M | 0.05% | +59,071+185.5% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 89,804 | $35.7M | 0.08% | +48,860+119.3% | Added |
| HSBC Holdings PLC | 89,517 | $35.7M | 0.02% | +16,503+22.6% | Added |
| Life Cycle Investment Partners Ltd | 88,076 | $35.0M | 0.25% | +88,076 | New |
| Bridgewater Associates, LP | 85,617 | $34.0M | 0.12% | +51,706+152.5% | Added |
| Hudson Bay Capital Management LP | 85,000 | $33.8M | 0.19% | +75,589+803.2% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 80,101 | $31.9M | 0.05% | +69,430+650.6% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 79,397 | $31.6M | 0.07% | +1,936+2.5% | Added |
| Millennium Management LLC | 75,430 | $30.0M | 0.02% | −474,501−86.3% | Reduced |
| Casdin Capital, LLC | 75,000 | $29.8M | 1.85% | +20,000+36.4% | Added |
| Storebrand Asset Management AS | 74,780 | $29.7M | 0.08% | +2,763+3.8% | Added |
| Rock Springs Capital Management LP | 71,250 | $28.3M | 1.45% | −3,000−4.0% | Reduced |
| Fiera Capital Corp | 70,720 | $28.1M | 0.09% | +16,916+31.4% | Added |
| Soleus Capital Management, L.P. | 70,000 | $27.8M | 1.18% | +54,750+359.0% | Added |
| Driehaus Capital Management LLC | 69,778 | $27.7M | 0.19% | +8,399+13.7% | Added |
| Schroder Investment Management Group | 68,049 | $27.0M | 0.02% | +57,231+529.0% | Added |
| Deerfield Management Company, L.P. (Series C) | 67,935 | $27.0M | 0.35% | 00.0% | Unchanged |
| Capital International Ltd | 67,667 | $26.9M | 0.95% | −10,556−13.5% | Reduced |
| Danske Bank A/S | 67,201 | $26.7M | 0.06% | +9,794+17.1% | Added |
| National Bank of Canada | 66,433 | $26.4M | 0.03% | +65,476+6,841.8% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 66,218 | $26.3M | 0.11% | −13,434−16.9% | Reduced |
| State of Wisconsin Investment Board | 66,065 | $26.3M | 0.06% | −2,464−3.6% | Reduced |
| Asset Management One Co.,Ltd. | 65,187 | $26.0M | 0.07% | −4,423−6.4% | Reduced |
| Ieq Capital, LLC | 64,905 | $25.8M | 0.08% | +2,728+4.4% | Added |
| New York State Common Retirement Fund | 64,424 | $25.6M | 0.03% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 63,412 | $25.2M | 0.02% | −4,260−6.3% | Reduced |
| Swedbank AB | 61,942 | $24.6M | 0.02% | −1,636−2.6% | Reduced |
| Integral Health Asset Management, LLC | 60,000 | $23.9M | 1.21% | 00.0% | Unchanged |
| Capital International Inc | 59,552 | $23.7M | 0.19% | −16,086−21.3% | Reduced |
| LMR Partners LLP | 59,022 | $23.5M | 0.23% | +59,022 | New |
| Ensign Peak Advisors, Inc | 57,932 | $23.0M | 0.04% | −9,801−14.5% | Reduced |
| Great West Life Assurance Co | 57,879 | $23.0M | 0.04% | −35,213−37.8% | Reduced |
| Treasurer of the State of North Carolina | 53,114 | $21.1M | 0.07% | −3,009−5.4% | Reduced |
| Caisse de Depot Et Placement du Quebec | 51,598 | $20.5M | 0.03% | +33,772+189.5% | Added |
| Voleon Capital Management LP | 51,117 | $20.3M | 0.44% | +17,152+50.5% | Added |
| KLP Kapitalforvaltning AS | 50,440 | $20.1M | 0.08% | +1,640+3.4% | Added |
| Mirae Asset Global Investments Co., Ltd. | 49,462 | $19.7M | 0.05% | +43,302+703.0% | Added |
| Frontier Capital Management Co LLC | 48,859 | $19.4M | 0.21% | −70,019−58.9% | Reduced |
| Andra AP-fonden | 48,540 | $19.3M | 0.24% | +27,840+134.5% | Added |
| Van Eck Associates Corp | 47,922 | $19.1M | 0.02% | +6,789+16.5% | Added |
| Antipodes Partners Ltd | 47,886 | $19.0M | 0.40% | +15,930+49.8% | Added |
| Allianz Asset Management GmbH | 47,875 | $19.0M | 0.02% | −58,941−55.2% | Reduced |
| Parkman Healthcare Partners LLC | 47,703 | $19.0M | 1.81% | −39,987−45.6% | Reduced |
| Intech Investment Management LLC | 46,710 | $18.6M | 0.17% | +40,898+703.7% | Added |
| Forsta Ap-Fonden | 46,420 | $18.5M | 0.11% | +18,520+66.4% | Added |
| LPL Financial LLC | 45,919 | $18.3M | 0.00% | −2,561−5.3% | Reduced |
| DekaBank Deutsche Girozentrale | 113,193 | $18.2M | 0.03% | 00.0% | Unchanged |
| Rhenman & Partners Asset Management AB | 45,675 | $18.2M | 1.70% | +13,800+43.3% | Added |
| Rafferty Asset Management, LLC | 45,031 | $17.9M | 0.06% | +27,880+162.6% | Added |
| State of New Jersey Common Pension Fund D | 44,976 | $17.9M | 0.06% | −556−1.2% | Reduced |
| Schonfeld Strategic Advisors LLC | 44,894 | $17.9M | 0.09% | +35,185+362.4% | Added |
| Advisor Group Holdings, Inc. | 44,718 | $17.8M | 0.03% | +19,780+79.3% | Added |
| Parnassus Investments | 44,560 | $17.7M | 0.05% | +7,546+20.4% | Added |
| Public Employees Retirement System of Ohio | 44,498 | $17.7M | 0.06% | +5,504+14.1% | Added |
| Natixis Advisors, L.P. | 44,335 | $17.6M | 0.02% | +22,653+104.5% | Added |
| Alliancebernstein L.P. | 44,319 | $17.6M | 0.01% | +543+1.2% | Added |
| Mariner, LLC | 42,443 | $16.9M | 0.02% | +16,111+61.2% | Added |
| Mediolanum International Funds Ltd | 42,476 | $16.9M | 0.17% | +17,025+66.9% | Added |
| Lansforsakringar Fondforvaltning AB (publ) | 42,340 | $16.8M | 0.08% | −64−0.2% | Reduced |
| NEOS Investment Management LLC | 40,701 | $16.2M | 0.09% | +38,138+1,488.0% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 40,459 | $16.1M | 0.03% | +40,459 | New |
| Tredje AP-fonden | 40,447 | $16.1M | 0.12% | +26,991+200.6% | Added |
| Guggenheim Capital LLC | 40,135 | $16.0M | 0.12% | +31,510+365.3% | Added |
| Natixis | 39,779 | $15.8M | 0.06% | +39,779 | New |
| Gotham Asset Management, LLC | 39,622 | $15.8M | 0.06% | +11,487+40.8% | Added |
| Resona Asset Management Co.,Ltd. | 39,247 | $15.6M | 0.08% | −2,250−5.4% | Reduced |
| Bronte Capital Management Pty Ltd. | 38,864 | $15.5M | 1.62% | +3,890+11.1% | Added |
| Citadel Advisors LLC | 38,459 | $15.3M | 0.01% | −183,384−82.7% | Reduced |
| Polymer Capital Management (HK) LTD | 36,765 | $14.6M | 2.28% | +7,865+27.2% | Added |
| Arizona State Retirement System | 36,390 | $14.5M | 0.08% | −2,122−5.5% | Reduced |
| PensionDanmark Pensionsforsikringsaktieselskab | 36,262 | $14.4M | 0.13% | +36,262 | New |
| Groupama Asset Managment | 35,878 | $14.3M | 0.21% | +3,796+11.8% | Added |
| Nissay Asset Management Corp | 35,813 | $14.2M | 0.07% | +19,238+116.1% | Added |
| Lord, Abbett & Co. LLC | 35,406 | $14.1M | 0.04% | −31,814−47.3% | Reduced |
| PFA Pension, Forsikringsaktieselskab | 35,405 | $14.1M | 0.04% | +35,405 | New |
| Bank of Montreal | 35,116 | $14.0M | 0.01% | +25,183+253.5% | Added |
| Eventide Asset Management, LLC | 34,035 | $13.5M | 0.21% | −67,704−66.5% | Reduced |
| Rosenblum Silverman Sutton S F Inc | 33,180 | $13.2M | 3.05% | −822−2.4% | Reduced |
| Teachers Retirement System of the State of Kentucky | 31,616 | $12.6M | 0.09% | −1,202−3.7% | Reduced |
| Panagora Asset Management Inc | 30,843 | $12.3M | 0.04% | −31,511−50.5% | Reduced |
| DnB Asset Management AS | 30,707 | $12.2M | 0.04% | −3,561−10.4% | Reduced |
| Jump Financial, LLC | 30,562 | $12.2M | 0.15% | −4,315−12.4% | Reduced |
| GF Fund Management Co. Ltd. | 30,462 | $12.1M | 0.21% | +27,665+989.1% | Added |
| Zurich Insurance Group Ltd | 30,322 | $12.1M | 0.08% | +334+1.1% | Added |
| Fjarde Ap-Fonden /Fourth Swedish National Pension Fund | 30,215 | $12.0M | 0.10% | 00.0% | Unchanged |
| Oddo BHF Asset Management SAS | 30,133 | $12.0M | 0.45% | −7,794−20.6% | Reduced |
| CIBC Asset Management Inc | 29,832 | $11.9M | 0.03% | +24,334+442.6% | Added |
| STRS Ohio | 28,036 | $11.1M | 0.04% | +51+0.2% | Added |
| U.S. Capital Wealth Advisors, LLC | 27,343 | $10.9M | 0.28% | −201−0.7% | Reduced |
| Xponance, Inc. | 27,328 | $10.9M | 0.08% | +1,176+4.5% | Added |
| Trexquant Investment LP | 26,741 | $10.6M | 0.09% | +14,345+115.7% | Added |
| EFG International AG | 26,400 | $10.5M | 0.20% | +26,400 | New |
| Jefferies Financial Group Inc. | 26,322 | $10.5M | 0.09% | +9,780+59.1% | Added |
| IFM Investors Pty Ltd | 26,238 | $10.4M | 0.09% | +197+0.8% | Added |