Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2025 年第 4 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2025/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 494
- 較 2025 年第 3 季 +68 家
- 持有股數
- 1.70 億
- 較 2025 年第 3 季 +278.5 萬 (+1.7%)
- 總市值
- $134.6 億
- 較 2025 年第 3 季 +$25.0 億 (+22.8%)
- 新進機構
- 112
- 另有 167 家加碼
- 清倉機構
- 44
- 另有 142 家減碼
另有 11 家機構在 2025 年第 3 季持有、還沒有申報 2025 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2025 年第 4 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2025 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 25,017 | $197.9 萬 | 0.29% | +19,554+357.9% | 加碼 |
| Profund Advisors LLC | 26,673 | $211.0 萬 | 0.06% | +741+2.9% | 加碼 |
| HSBC Holdings PLC | 26,941 | $214.2 萬 | 0.00% | −18,515−40.7% | 減碼 |
| Swedbank AB | 27,253 | $215.6 萬 | 0.00% | +27,253 | 新進 |
| Qsemble Capital Management, LP | 27,579 | $218.2 萬 | 0.18% | +27,579 | 新進 |
| Standard Life Aberdeen plc | 28,926 | $228.8 萬 | 0.00% | −58,998−67.1% | 減碼 |
| Kornitzer Capital Management Inc | 29,105 | $230.2 萬 | 0.05% | +29,105 | 新進 |
| Assenagon Asset Management S.A. | 29,316 | $231.9 萬 | 0.00% | −282,981−90.6% | 減碼 |
| Jane Street Group, LLC | 30,471 | $241.1 萬 | 0.00% | −334,599−91.7% | 減碼 |
| Wolverine Asset Management LLC | 30,515 | $241.4 萬 | 0.03% | +30,515 | 新進 |
| PEAK6 LLC | 30,642 | $242.4 萬 | 0.07% | +24,530+401.3% | 加碼 |
| LPL Financial LLC | 31,069 | $245.8 萬 | 0.00% | +6,606+27.0% | 加碼 |
| Mutual of America Capital Management LLC | 31,459 | $248.9 萬 | 0.03% | +31,459 | 新進 |
| Twin Tree Management, LP | 32,476 | $256.9 萬 | 0.26% | +3,901+13.7% | 加碼 |
| Prelude Capital Management, LLC | 32,481 | $257.0 萬 | 0.19% | −4,812−12.9% | 減碼 |
| Susquehanna International Group, LLP | 32,504 | $257.1 萬 | 0.00% | −388,446−92.3% | 減碼 |
| Lisanti Capital Growth, LLC | 32,789 | $259.4 萬 | 0.61% | −59,335−64.4% | 減碼 |
| Calamos Advisors LLC | 33,189 | $262.6 萬 | 0.01% | +7,326+28.3% | 加碼 |
| SG Americas Securities, LLC | 33,409 | $264.3 萬 | 0.00% | +28,259+548.7% | 加碼 |
| KLP Kapitalforvaltning AS | 33,500 | $265.0 萬 | 0.01% | +2,000+6.3% | 加碼 |
| Blair William & Co | 33,788 | $267.3 萬 | 0.01% | −583−1.7% | 減碼 |
| Pathstone Holdings, LLC | 34,304 | $271.4 萬 | 0.01% | +702+2.1% | 加碼 |
| Acadian Asset Management LLC | 34,691 | $274.1 萬 | 0.00% | −75,753−68.6% | 減碼 |
| Raiffeisen Bank International AG | 35,000 | $276.4 萬 | 0.04% | −15,000−30.0% | 減碼 |
| Bamco Inc | 36,000 | $284.8 萬 | 0.01% | +11,000+44.0% | 加碼 |
| Bank of Montreal | 36,362 | $287.7 萬 | 0.00% | −711,040−95.1% | 減碼 |
| Stanley-Laman Group, Ltd. | 36,512 | $288.8 萬 | 0.37% | +738+2.1% | 加碼 |
| Guggenheim Capital LLC | 37,709 | $298.3 萬 | 0.02% | +2,352+6.7% | 加碼 |
| Grandfield & Dodd, LLC | 37,821 | $299.2 萬 | 0.17% | +146+0.4% | 加碼 |
| West Michigan Advisors, LLC | 38,413 | $303.9 萬 | 0.70% | +38,413 | 新進 |
| Fred Alger Management, LLC | 38,423 | $304.0 萬 | 0.01% | −3,978−9.4% | 減碼 |
| China Universal Asset Management Co., Ltd. | 42,394 | $335.4 萬 | 0.26% | +14,455+51.7% | 加碼 |
| Arizona State Retirement System | 42,421 | $335.6 萬 | 0.02% | −2,310−5.2% | 減碼 |
| Gotham Asset Management, LLC | 43,212 | $341.9 萬 | 0.01% | +11,060+34.4% | 加碼 |
| Russell Investments Group, Ltd. | 43,912 | $347.4 萬 | 0.00% | −33,381−43.2% | 減碼 |
| Future Fund LLC | 45,851 | $362.7 萬 | 1.28% | +9,695+26.8% | 加碼 |
| One Capital Management, LLC | 46,121 | $364.9 萬 | 0.11% | +9,695+26.6% | 加碼 |
| Lazard Asset Management LLC | 46,402 | $367.1 萬 | 0.01% | −17,389−27.3% | 減碼 |
| Van Eck Associates Corp | 47,102 | $372.6 萬 | 0.00% | −64,717−57.9% | 減碼 |
| Quantinno Capital Management LP | 47,378 | $374.8 萬 | 0.01% | +11,263+31.2% | 加碼 |
| Atika Capital Management LLC | 47,488 | $375.7 萬 | 0.52% | +25,988+120.9% | 加碼 |
| Public Employees Retirement System of Ohio | 47,598 | $376.5 萬 | 0.01% | −947−2.0% | 減碼 |
| Mariner, LLC | 47,740 | $377.7 萬 | 0.00% | +23,513+97.1% | 加碼 |
| Handelsbanken Fonder AB | 47,911 | $379.0 萬 | 0.01% | −4,000−7.7% | 減碼 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 48,921 | $387.0 萬 | 0.01% | +3,701+8.2% | 加碼 |
| Capital Counsel LLC | 49,605 | $392.4 萬 | 0.15% | 00.0% | 不變 |
| Jefferies Financial Group Inc. | 50,395 | $398.7 萬 | 0.03% | +40,226+395.6% | 加碼 |
| Alpine Global Management, LLC | 53,600 | $424.0 萬 | 0.94% | −2,300−4.1% | 減碼 |
| Ensign Peak Advisors, Inc | 53,664 | $424.5 萬 | 0.01% | +26,069+94.5% | 加碼 |
| EAM Investors, LLC | 53,914 | $426.5 萬 | 0.48% | −1,063−1.9% | 減碼 |
| DekaBank Deutsche Girozentrale | 93,807 | $429.9 萬 | 0.01% | 00.0% | 不變 |
| PDT Partners, LLC | 54,365 | $430.1 萬 | 0.28% | 00.0% | 不變 |
| Creative Planning | 54,774 | $433.3 萬 | 0.00% | +3,300+6.4% | 加碼 |
| State of New Jersey Common Pension Fund D | 54,783 | $433.4 萬 | 0.02% | −5,034−8.4% | 減碼 |
| BLB&B Advisors, LLC | 61,520 | $486.7 萬 | 0.20% | −57,080−48.1% | 減碼 |
| BI Asset Management Fondsmaeglerselskab A/S | 62,073 | $491.1 萬 | 0.04% | +62,073 | 新進 |
| Treasurer of the State of North Carolina | 66,262 | $524.2 萬 | 0.02% | −3,600−5.2% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 66,849 | $528.8 萬 | 0.04% | −2,475−3.6% | 減碼 |
| J. Goldman & Co LP | 67,639 | $535.1 萬 | 0.21% | −28,559−29.7% | 減碼 |
| Bridgewater Associates, LP | 67,706 | $535.6 萬 | 0.02% | +24,128+55.4% | 加碼 |
| Janus Henderson Group PLC | 68,191 | $539.6 萬 | 0.00% | +4,314+6.8% | 加碼 |
| Hillsdale Investment Management Inc. | 70,900 | $560.9 萬 | 0.15% | 00.0% | 不變 |
| Erste Asset Management GmbH | 71,800 | $574.3 萬 | 0.05% | 00.0% | 不變 |
| Voya Investment Management LLC | 73,760 | $583.5 萬 | 0.01% | −37,829−33.9% | 減碼 |
| Rafferty Asset Management, LLC | 73,983 | $585.3 萬 | 0.02% | −51,790−41.2% | 減碼 |
| EFG International AG | 75,276 | $595.6 萬 | 0.12% | +75,276 | 新進 |
| Boothbay Fund Management, LLC | 75,562 | $597.8 萬 | 0.16% | −87,900−53.8% | 減碼 |
| Victory Capital Management Inc | 80,729 | $638.6 萬 | 0.00% | +62,518+343.3% | 加碼 |
| ExodusPoint Capital Management, LP | 83,875 | $663.5 萬 | 0.07% | −68,250−44.9% | 減碼 |
| Nicola Wealth Management Ltd. | 87,000 | $688.3 萬 | 0.63% | 00.0% | 不變 |
| Citigroup Inc | 89,340 | $706.8 萬 | 0.00% | −66,513−42.7% | 減碼 |
| Envestnet Asset Management Inc | 89,919 | $711.3 萬 | 0.00% | +62,410+226.9% | 加碼 |
| HealthInvest Partners AB | 92,377 | $730.8 萬 | 2.33% | +92,377 | 新進 |
| Millennium Management LLC | 93,262 | $737.8 萬 | 0.01% | −686,308−88.0% | 減碼 |
| Nikko Asset Management Americas, Inc. | 93,571 | $740.1 萬 | 0.09% | −21,021−18.3% | 減碼 |
| Sumitomo Mitsui Trust Holdings, Inc. | 93,751 | $741.7 萬 | 0.00% | −21,021−18.3% | 減碼 |
| State of Wisconsin Investment Board | 94,761 | $749.7 萬 | 0.02% | −2,076−2.1% | 減碼 |
| Susquehanna Portfolio Strategies, LLC | 95,960 | $759.1 萬 | 0.12% | 00.0% | 不變 |
| Simplex Trading, LLC | 96,647 | $764.6 萬 | 0.22% | −3,559−3.6% | 減碼 |
| DCF Advisers, LLC | 103,000 | $814.8 萬 | 2.69% | −5,413−5.0% | 減碼 |
| Neuberger Berman Group LLC | 108,044 | $854.7 萬 | 0.01% | −6,699−5.8% | 減碼 |
| Kennedy Capital Management, Inc. | 109,291 | $864.6 萬 | 0.18% | −13,475−11.0% | 減碼 |
| Healthcare of Ontario Pension Plan Trust Fund | 110,000 | $870.2 萬 | 0.01% | −6,000−5.2% | 減碼 |
| Skandinaviska Enskilda Banken AB (publ) | 115,293 | $912.2 萬 | 0.04% | −40,497−26.0% | 減碼 |
| SEI Investments Co | 115,917 | $917.0 萬 | 0.01% | −3,111−2.6% | 減碼 |
| Exome Asset Management LLC | 116,515 | $921.8 萬 | 4.55% | −14,501−11.1% | 減碼 |
| Balyasny Asset Management LLC | 120,577 | $953.9 萬 | 0.02% | −639,534−84.1% | 減碼 |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 121,628 | $962.2 萬 | 0.35% | +121,628 | 新進 |
| Edmond de Rothschild Holding S.A. | 122,190 | $966.6 萬 | 0.14% | −34,500−22.0% | 減碼 |
| Algert Global LLC | 127,205 | $1,006 萬 | 0.16% | −125,076−49.6% | 減碼 |
| Trexquant Investment LP | 132,241 | $1,046 萬 | 0.09% | −82,880−38.5% | 減碼 |
| Aquatic Capital Management LLC | 132,826 | $1,051 萬 | 0.30% | −26,219−16.5% | 減碼 |
| State Board of Administration of Florida Retirement System | 135,878 | $1,075 萬 | 0.02% | −7,656−5.3% | 減碼 |
| Adage Capital Partners GP, L.L.C. | 140,000 | $1,108 萬 | 0.02% | −1,175,000−89.4% | 減碼 |
| Fisher Asset Management, LLC | 141,615 | $1,120 萬 | 0.00% | +135,405+2,180.4% | 加碼 |
| California State Teachers Retirement System | 144,173 | $1,141 萬 | 0.01% | −939−0.6% | 減碼 |
| Artia Global Partners LP | 144,376 | $1,142 萬 | 1.84% | +84,200+139.9% | 加碼 |
| ADAR1 Capital Management, LLC | 147,130 | $1,164 萬 | 0.87% | +13,312+9.9% | 加碼 |
| Great Lakes Advisors, LLC | 149,180 | $1,180 萬 | 0.10% | −37,770−20.2% | 減碼 |
| Deutsche Bank AG | 149,443 | $1,182 萬 | 0.00% | +60,640+68.3% | 加碼 |