Ionis Pharmaceuticals Inc
IONS- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
近 90 天，Ionis Pharmaceuticals Inc 內部人申報 1 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 515 家機構在 13F 申報持有，市值合計 $142.6 億；大師中只有方舟投資持有。
2025 年第 1 季 13F 持有人
Ionis Pharmaceuticals Inc 在 2025/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 344
- 較 2024 年第 4 季 −6 家
- 持有股數
- 1.67 億
- 較 2024 年第 4 季 +668.6 萬 (+4.2%)
- 總市值
- $50.3 億
- 較 2024 年第 4 季 −$5.65 億 (−10.1%)
- 新進機構
- 54
- 另有 102 家加碼
- 清倉機構
- 60
- 另有 123 家減碼
另有 6 家機構在 2024 年第 4 季持有、還沒有申報 2025 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 IONS 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 515 | $142.6 億 |
| 2026 年第 1 季 | 497 | $129.7 億 |
| 2025 年第 4 季 | 494 | $134.6 億 |
| 2025 年第 3 季 | 437 | $110.1 億 |
| 2025 年第 2 季 | 363 | $66.7 億 |
| 2025 年第 1 季 | 344 | $50.3 億 |
| 2024 年第 4 季 | 356 | $56.1 億 |
| 2024 年第 3 季 | 354 | $63.1 億 |
| 2024 年第 2 季 | 357 | $68.3 億 |
| 2024 年第 1 季 | 361 | $61.7 億 |
| 2023 年第 4 季 | 365 | $72.1 億 |
| 2023 年第 3 季 | 312 | $63.5 億 |
| 2023 年第 2 季 | 305 | $56.0 億 |
| 2023 年第 1 季 | 315 | $46.9 億 |
| 2022 年第 4 季 | 339 | $49.3 億 |
| 2022 年第 3 季 | 350 | $55.9 億 |
| 2022 年第 2 季 | 351 | $46.1 億 |
| 2022 年第 1 季 | 333 | $46.3 億 |
| 2021 年第 4 季 | 341 | $37.5 億 |
| 2021 年第 3 季 | 326 | $40.8 億 |
| 2021 年第 2 季 | 338 | $49.6 億 |
| 2021 年第 1 季 | 365 | $55.5 億 |
2025 年第 1 季持有機構
每家機構持有 Ionis Pharmaceuticals Inc 的股數、市值與佔組合比重；股數變化跟 2024 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| SummitTX Capital, L.P. | 35,103 | $105.9 萬 | 0.05% | +35,103 | 新進 |
| Creative Planning | 36,122 | $109.0 萬 | 0.00% | −10,681−22.8% | 減碼 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 36,509 | $110.1 萬 | 0.00% | +187+0.5% | 加碼 |
| Capital Counsel LLC | 37,080 | $111.9 萬 | 0.05% | 00.0% | 不變 |
| Grandfield & Dodd, LLC | 37,761 | $113.9 萬 | 0.07% | +1,874+5.2% | 加碼 |
| Prelude Capital Management, LLC | 37,772 | $114.0 萬 | 0.11% | +22,177+142.2% | 加碼 |
| Blair William & Co | 38,381 | $115.8 萬 | 0.00% | −1,501−3.8% | 減碼 |
| Arizona State Retirement System | 40,687 | $122.8 萬 | 0.01% | −460−1.1% | 減碼 |
| Point72 (DIFC) Ltd | 41,347 | $124.7 萬 | 0.12% | +41,347 | 新進 |
| Guggenheim Capital LLC | 41,414 | $124.9 萬 | 0.01% | +6,041+17.1% | 加碼 |
| NJ State Employees Deferred Compensation Plan | 42,000 | $126.7 萬 | 0.16% | 00.0% | 不變 |
| Raiffeisen Bank International AG | 41,754 | $129.9 萬 | 0.02% | +40,000+2,280.5% | 加碼 |
| Handelsbanken Fonder AB | 43,211 | $130.4 萬 | 0.01% | −600−1.4% | 減碼 |
| Great West Life Assurance Co | 43,853 | $132.6 萬 | 0.00% | +4,639+11.8% | 加碼 |
| Readystate Asset Management LP | 46,394 | $140.0 萬 | 0.07% | +46,394 | 新進 |
| Schroder Investment Management Group | 45,950 | $143.1 萬 | 0.00% | −54,709−54.4% | 減碼 |
| Public Employees Retirement System of Ohio | 48,177 | $145.3 萬 | 0.01% | −5,571−10.4% | 減碼 |
| Verition Fund Management LLC | 52,287 | $157.7 萬 | 0.01% | −147,897−73.9% | 減碼 |
| Erste Asset Management GmbH | 51,300 | $159.8 萬 | 0.02% | 00.0% | 不變 |
| Jane Street Group, LLC | 54,117 | $163.3 萬 | 0.00% | −110,517−67.1% | 減碼 |
| Ensign Peak Advisors, Inc | 55,100 | $166.2 萬 | 0.00% | +1,780+3.3% | 加碼 |
| Davenport & Co LLC | 56,393 | $170.1 萬 | 0.01% | −6,347−10.1% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 57,549 | $173.6 萬 | 0.02% | +854+1.5% | 加碼 |
| Capital Fund Management S.A. | 58,014 | $175.0 萬 | 0.02% | +58,014 | 新進 |
| Skandinaviska Enskilda Banken AB (publ) | 59,626 | $179.9 萬 | 0.01% | 00.0% | 不變 |
| Avidity Partners Management LP | 60,000 | $181.0 萬 | 0.37% | +60,000 | 新進 |
| State of New Jersey Common Pension Fund D | 60,662 | $183.0 萬 | 0.01% | −2,544−4.0% | 減碼 |
| Lazard Asset Management LLC | 60,758 | $183.2 萬 | 0.00% | +54,201+826.6% | 加碼 |
| Voya Investment Management LLC | 63,767 | $192.4 萬 | 0.00% | −28,764−31.1% | 減碼 |
| Sphera Funds Management Ltd. | 63,821 | $192.5 萬 | 0.47% | 00.0% | 不變 |
| Simplex Trading, LLC | 64,581 | $194.8 萬 | 0.07% | +64,581 | 新進 |
| Janus Henderson Group PLC | 63,877 | $199.0 萬 | 0.00% | 00.0% | 不變 |
| Granite Investment Partners, LLC | 68,434 | $206.5 萬 | 0.10% | −5,432−7.4% | 減碼 |
| SEI Investments Co | 71,558 | $215.9 萬 | 0.00% | +1,467+2.1% | 加碼 |
| Treasurer of the State of North Carolina | 71,593 | $216.0 萬 | 0.01% | +2,790+4.1% | 加碼 |
| Susquehanna International Group, LLP | 71,811 | $216.7 萬 | 0.00% | +45,747+175.5% | 加碼 |
| HSBC Holdings PLC | 74,833 | $222.2 萬 | 0.00% | −8,222−9.9% | 減碼 |
| New York State Common Retirement Fund | 78,261 | $236.1 萬 | 0.00% | −6,000−7.1% | 減碼 |
| Rhenman & Partners Asset Management AB | 81,000 | $244.4 萬 | 0.28% | −131,500−61.9% | 減碼 |
| Jump Financial, LLC | 81,321 | $245.3 萬 | 0.04% | +41,584+104.6% | 加碼 |
| Manufacturers Life Insurance Company, The | 83,440 | $251.7 萬 | 0.00% | −202,839−70.9% | 減碼 |
| Deutsche Bank AG | 84,810 | $255.9 萬 | 0.00% | −7,091−7.7% | 減碼 |
| Nicola Wealth Management Ltd. | 87,000 | $262.5 萬 | 0.26% | 00.0% | 不變 |
| UBS Oconnor LLC | 90,779 | $273.9 萬 | 0.07% | +30,199+49.8% | 加碼 |
| Walleye Capital LLC | 94,990 | $286.6 萬 | 0.03% | +78,735+484.4% | 加碼 |
| DCF Advisers, LLC | 95,000 | $286.6 萬 | 1.54% | +12,118+14.6% | 加碼 |
| DekaBank Deutsche Girozentrale | 93,807 | $287.2 萬 | 0.01% | 00.0% | 不變 |
| PDT Partners, LLC | 96,056 | $289.8 萬 | 0.21% | +67,062+231.3% | 加碼 |
| Alliancebernstein L.P. | 100,749 | $304.0 萬 | 0.00% | +48,613+93.2% | 加碼 |
| Neuberger Berman Group LLC | 102,473 | $309.2 萬 | 0.00% | +5,842+6.0% | 加碼 |
| State of Wisconsin Investment Board | 108,316 | $326.8 萬 | 0.01% | +7,085+7.0% | 加碼 |
| American Century Companies Inc | 116,768 | $352.3 萬 | 0.00% | +116,768 | 新進 |
| Edmond de Rothschild Holding S.A. | 124,200 | $374.7 萬 | 0.07% | +124,200 | 新進 |
| Connor, Clark & Lunn Investment Management Ltd. | 129,273 | $390.0 萬 | 0.02% | +3,884+3.1% | 加碼 |
| California State Teachers Retirement System | 132,238 | $399.0 萬 | 0.00% | −1,664−1.2% | 減碼 |
| Exome Asset Management LLC | 135,616 | $409.2 萬 | 3.66% | +74,249+121.0% | 加碼 |
| Nikko Asset Management Americas, Inc. | 142,433 | $429.6 萬 | 0.06% | −14,224−9.1% | 減碼 |
| Sumitomo Mitsui Trust Holdings, Inc. | 142,433 | $429.7 萬 | 0.00% | −14,224−9.1% | 減碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 143,870 | $434.1 萬 | 0.01% | +143,870 | 新進 |
| Raymond James Financial Inc | 148,690 | $448.6 萬 | 0.00% | +43,071+40.8% | 加碼 |
| Tang Capital Management LLC | 150,000 | $452.6 萬 | 0.25% | 00.0% | 不變 |
| Kennedy Capital Management, Inc. | 150,424 | $453.8 萬 | 0.11% | −72,854−32.6% | 減碼 |
| BLB&B Advisors, LLC | 152,200 | $459.2 萬 | 0.23% | +150+0.1% | 加碼 |
| State Board of Administration of Florida Retirement System | 152,315 | $459.5 萬 | 0.01% | 00.0% | 不變 |
| Renaissance Technologies LLC | 153,514 | $463.2 萬 | 0.01% | −52,000−25.3% | 減碼 |
| Sonora Investment Management Group, LLC | 154,147 | $465.1 萬 | 0.37% | +5,371+3.6% | 加碼 |
| Aquatic Capital Management LLC | 156,157 | $471.1 萬 | 0.12% | −73,859−32.1% | 減碼 |
| Susquehanna Fundamental Investments, LLC | 158,609 | $478.5 萬 | 0.08% | −54,406−25.5% | 減碼 |
| Rafferty Asset Management, LLC | 176,248 | $531.7 萬 | 0.02% | −61,089−25.7% | 減碼 |
| GW&K Investment Management, LLC | 182,309 | $550.0 萬 | 0.05% | −4,911−2.6% | 減碼 |
| Sicart Associates LLC | 185,646 | $560.1 萬 | 1.94% | −175−0.1% | 減碼 |
| Tocqueville Asset Management L.P. | 187,395 | $565.4 萬 | 0.09% | −164,745−46.8% | 減碼 |
| Rhumbline Advisers | 188,216 | $567.8 萬 | 0.01% | −3,677−1.9% | 減碼 |
| California Public Employees Retirement System | 191,004 | $576.3 萬 | 0.00% | −1,126−0.6% | 減碼 |
| Stifel Financial Corp | 200,942 | $606.2 萬 | 0.01% | −10,551−5.0% | 減碼 |
| Artisan Partners Limited Partnership | 203,178 | $613.0 萬 | 0.01% | −49,457−19.6% | 減碼 |
| Orion Investment Co | 215,290 | $649.5 萬 | 2.67% | −710−0.3% | 減碼 |
| Nomura Holdings Inc | 236,426 | $713.3 萬 | 0.04% | −120,829−33.8% | 減碼 |
| CI Private Wealth, LLC | 237,133 | $715.4 萬 | 0.01% | −2,030−0.8% | 減碼 |
| Great Point Partners LLC | 250,000 | $754.3 萬 | 4.10% | −255,007−50.5% | 減碼 |
| Wells Fargo & Company | 256,233 | $773.1 萬 | 0.00% | −74,776−22.6% | 減碼 |
| Privium Fund Management B.V. | 267,594 | $807.3 萬 | 2.10% | +800+0.3% | 加碼 |
| Swiss National Bank | 275,300 | $830.6 萬 | 0.01% | −3,900−1.4% | 減碼 |
| Sector Gamma AS | 285,842 | $862.4 萬 | 2.76% | +50,000+21.2% | 加碼 |
| Point72 Asset Management, L.P. | 287,204 | $866.5 萬 | 0.02% | +287,204 | 新進 |
| Squarepoint Ops LLC | 305,373 | $921.3 萬 | 0.02% | +138,905+83.4% | 加碼 |
| J. Goldman & Co LP | 307,770 | $928.5 萬 | 0.33% | −299,729−49.3% | 減碼 |
| BNP Paribas Arbitrage, SA | 308,293 | $930.1 萬 | 0.01% | +53,772+21.1% | 加碼 |
| Nuveen, LLC | 308,777 | $931.6 萬 | 0.00% | +308,777 | 新進 |
| Sovran Advisors, LLC | 328,904 | $934.1 萬 | 1.21% | +157,092+91.4% | 加碼 |
| Legal & General Group Plc | 338,462 | $1,021 萬 | 0.00% | +170,382+101.4% | 加碼 |
| Barclays PLC | 353,937 | $1,068 萬 | 0.00% | −242,135−40.6% | 減碼 |
| Baker Bros. Advisors LP | 357,915 | $1,080 萬 | 0.12% | 00.0% | 不變 |
| Ameriprise Financial Inc | 360,188 | $1,087 萬 | 0.00% | −27,260−7.0% | 減碼 |
| Voloridge Investment Management, LLC | 377,204 | $1,138 萬 | 0.04% | +60,261+19.0% | 加碼 |
| C WorldWide Group Holding A/S | 400,000 | $1,207 萬 | 0.15% | 00.0% | 不變 |
| JPMorgan Chase & Co | 421,511 | $1,272 萬 | 0.00% | +5,592+1.3% | 加碼 |
| Citigroup Inc | 426,480 | $1,287 萬 | 0.01% | +257,325+152.1% | 加碼 |
| Standard Life Aberdeen plc | 446,197 | $1,350 萬 | 0.03% | +44,696+11.1% | 加碼 |
| Teacher Retirement System of Texas | 500,451 | $1,510 萬 | 0.06% | +434,659+660.7% | 加碼 |