Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Zymeworks Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 212
- +4 vs. Q4 2025
- Shares held
- 70.3M
- +1.16M (+1.7%) vs. Q4 2025
- Total value
- $1.76B
- −$60.1M (−3.3%) vs. Q4 2025
- New holders
- 40
- 77 more added
- Sold out
- 36
- 58 more reduced
2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| State Street Corp | 1,011,777 | $25.3M | 0.00% | −25,865−2.5% | Reduced |
| Nextech Invest, Ltd. | 1,113,946 | $27.9M | 1.96% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 1,139,135 | $28.5M | 0.01% | −20,080−1.7% | Reduced |
| Citadel Advisors LLC | 1,150,018 | $28.8M | 0.02% | +894,667+350.4% | Added |
| Vanguard Capital Management LLC | 1,705,580 | $42.7M | 0.00% | +1,705,580 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,908,039 | $47.8M | 0.06% | +85,991+4.7% | Added |
| Morgan Stanley | 2,480,568 | $62.1M | 0.00% | −112,512−4.3% | Reduced |
| Perceptive Advisors LLC | 3,510,078 | $87.9M | 1.74% | +248,228+7.6% | Added |
| BVF Inc | 3,734,142 | $93.5M | 2.98% | −204,499−5.2% | Reduced |
| BlackRock, Inc. | 4,553,888 | $114.0M | 0.00% | −41,660−0.9% | Reduced |
| Rubric Capital Management LP | 7,000,000 | $175.3M | 2.15% | +1,250,000+21.7% | Added |
| EcoR1 Capital, LLC | 22,970,388 | $575.2M | 24.58% | 00.0% | Unchanged |
| Siren, L.L.C. | 0 | $0 | 0.00% | −1,680,121−100.0% | Sold out |
| Vestal Point Capital, LP | 0 | $0 | 0.00% | −865,000−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −663,546−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −423,646−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −381,621−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −288,571−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −220,877−100.0% | Sold out |
| Jupiter Asset Management Ltd | 0 | $0 | 0.00% | −125,506−100.0% | Sold out |
| Opaleye Management Inc. | 0 | $0 | 0.00% | −108,929−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −101,274−100.0% | Sold out |
| Acuta Capital Partners, LLC | 0 | $0 | 0.00% | −80,143−100.0% | Sold out |
| NEOS Investment Management LLC | 0 | $0 | 0.00% | −77,115−100.0% | Sold out |
| Penserra Capital Management LLC | 0 | $0 | 0.00% | −60,146−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −34,631−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −31,415−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −24,103−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −23,333−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −22,643−100.0% | Sold out |
| Seven Fleet Capital Management LP | 0 | $0 | 0.00% | −20,600−100.0% | Sold out |
| Change Path, LLC | 0 | $0 | 0.00% | −18,264−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −13,252−100.0% | Sold out |
| Baader Bank INC | 0 | $0 | 0.00% | −10,013−100.0% | Sold out |
| VARCOV Co. | 0 | $0 | 0.00% | −9,818−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −8,841−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −8,313−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −8,020−100.0% | Sold out |
| Cresset Asset Management, LLC | 0 | $0 | 0.00% | −8,120−100.0% | Sold out |
| Apollon Wealth Management, LLC | 0 | $0 | 0.00% | −7,875−100.0% | Sold out |
| CFG Wealth Management Services, Inc. | 0 | $0 | 0.00% | −3,080−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −1,566−100.0% | Sold out |
| Thurston, Springer, Miller, Herd & Titak, Inc. | 0 | $0 | 0.00% | −610−100.0% | Sold out |
| Truvestments Capital LLC | 0 | $0 | 0.00% | −231−100.0% | Sold out |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −186−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −169−100.0% | Sold out |
| Quarry LP | 0 | $0 | 0.00% | −90−100.0% | Sold out |
| Innovative Advisory Group, LLC | 0 | $0 | 0.00% | −8−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Comerica Bank | – | – | – | – | Not filed |