Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Zymeworks Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 210
- +28 vs. Q3 2025
- Shares held
- 71.5M
- −2.08M (−2.8%) vs. Q3 2025
- Total value
- $1.88B
- +$625.5M (+49.8%) vs. Q3 2025
- New holders
- 47
- 71 more added
- Sold out
- 19
- 62 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| MAI Capital Management | 5 | $132 | 0.00% | +5 | New |
| Larson Financial Group LLC | 6 | $158 | 0.00% | +6 | New |
| Innovative Advisory Group, LLC | 8 | $211 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 11 | $290 | 0.00% | −1−8.3% | Reduced |
| Essential Partners LLC | 12 | $316 | 0.00% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 12 | $318 | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 18 | $474 | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 20 | $527 | 0.00% | +20 | New |
| International Assets Investment Management, LLC | 25 | $658 | 0.00% | +25 | New |
| Sunbelt Securities, Inc. | 27 | $711 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 54 | $1.00K | 0.00% | +1+1.9% | Added |
| Signaturefd, LLC | 42 | $1.11K | 0.00% | +42 | New |
| UMA Financial Services, Inc. | 51 | $1.34K | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 53 | $1.40K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 56 | $1.47K | 0.00% | +1+1.8% | Added |
| True Wealth Design, LLC | 58 | $1.53K | 0.00% | 00.0% | Unchanged |
| Bare Financial Services, Inc | 64 | $1.69K | 0.00% | 00.0% | Unchanged |
| Kilter Group LLC | 66 | $1.74K | 0.00% | 00.0% | Unchanged |
| Quarry LP | 90 | $2.37K | 0.00% | −2,852−96.9% | Reduced |
| IFP Advisors, Inc | 96 | $2.53K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 146 | $3.85K | 0.00% | +6+4.3% | Added |
| SRS Capital Advisors, Inc. | 169 | $4.45K | 0.00% | −2,812−94.3% | Reduced |
| EverSource Wealth Advisors, LLC | 182 | $4.79K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 186 | $5.00K | 0.00% | −100−35.0% | Reduced |
| Comerica Bank | 211 | $5.56K | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 230 | $6.05K | 0.00% | −50−17.9% | Reduced |
| Truvestments Capital LLC | 231 | $6.08K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 279 | $7.35K | 0.00% | +217+350.0% | Added |
| Los Angeles Capital Management LLC | 387 | $7.40K | 0.00% | +387 | New |
| US Bancorp | 287 | $7.56K | 0.00% | +39+15.7% | Added |
| TD Waterhouse Canada Inc. | 311 | $8.19K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 329 | $8.66K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 331 | $8.71K | 0.00% | +210+173.6% | Added |
| Huntington National Bank | 364 | $9.58K | 0.00% | +364 | New |
| Umb Bank N A | 466 | $12.3K | 0.00% | +466 | New |
| National Bank of Canada | 545 | $14.3K | 0.00% | −4−0.7% | Reduced |
| Federation des caisses Desjardins du Quebec | 570 | $15.0K | 0.00% | −300−34.5% | Reduced |
| Thurston, Springer, Miller, Herd & Titak, Inc. | 610 | $16.1K | 0.01% | +610 | New |
| NBC Securities, Inc. | 623 | $16.4K | 0.00% | +623 | New |
| The PNC Financial Services Group, Inc. | 781 | $20.6K | 0.00% | +468+149.5% | Added |
| Nisa Investment Advisors, LLC | 968 | $25.5K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 985 | $25.9K | 0.00% | +180+22.4% | Added |
| Optiver Holding B.V. | 1,148 | $30.3K | 0.00% | −362−24.0% | Reduced |
| DekaBank Deutsche Girozentrale | 3,843 | $35.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 1,353 | $35.6K | 0.00% | −9,948−88.0% | Reduced |
| Caitong International Asset Management Co., Ltd | 1,399 | $36.8K | 0.01% | +1,399 | New |
| GF Fund Management Co. Ltd. | 1,470 | $38.7K | 0.00% | −147−9.1% | Reduced |
| Amalgamated Bank | 1,566 | $41.0K | 0.00% | −314−16.7% | Reduced |
| Advisor Group Holdings, Inc. | 2,510 | $66.1K | 0.00% | +1,735+223.9% | Added |
| CFG Wealth Management Services, Inc. | 3,080 | $81.1K | 0.07% | +3,080 | New |
| Mirae Asset Global Investments Co., Ltd. | 3,637 | $95.8K | 0.00% | +731+25.2% | Added |
| Ameritas Investment Partners, Inc. | 4,164 | $109.6K | 0.00% | 00.0% | Unchanged |
| Cygnus Capital Advisors, LLC | 5,997 | $158.0K | 0.12% | +5,997 | New |
| CWM, LLC | 6,975 | $184.0K | 0.00% | +7+0.1% | Added |
| Persistent Asset Partners Ltd | 7,346 | $193.4K | 0.09% | +7,346 | New |
| Allspring Global Investments Holdings, LLC | 7,707 | $205.2K | 0.00% | +7,707 | New |
| Apollon Wealth Management, LLC | 7,875 | $207.3K | 0.00% | +7,875 | New |
| KLP Kapitalforvaltning AS | 8,000 | $210.6K | 0.00% | +700+9.6% | Added |
| Cresset Asset Management, LLC | 8,120 | $213.8K | 0.00% | +8,120 | New |
| Skopos Labs, Inc. | 8,020 | $214.5K | 0.01% | +8,020 | New |
| Quest Partners LLC | 8,313 | $218.9K | 0.01% | −158−1.9% | Reduced |
| Group One Trading, L.P. | 8,841 | $232.8K | 0.01% | +1,973+28.7% | Added |
| Voya Investment Management LLC | 9,234 | $243.1K | 0.00% | +9,234 | New |
| VARCOV Co. | 9,818 | $258.5K | 0.10% | +9,818 | New |
| Baader Bank INC | 10,013 | $263.5K | 0.02% | +10,013 | New |
| Abacus Wealth Partners, LLC | 10,222 | $269.1K | 0.03% | +10,222 | New |
| Arizona State Retirement System | 10,395 | $273.7K | 0.00% | −664−6.0% | Reduced |
| Virtus Investment Advisers, Inc. | 10,441 | $274.9K | 0.07% | +1,755+20.2% | Added |
| State of Wyoming | 10,875 | $286.3K | 0.03% | +10,875 | New |
| James Investment Research Inc | 10,925 | $287.7K | 0.03% | +347+3.3% | Added |
| Ewing Morris & Co. Investment Partners Ltd. | 10,850 | $289.2K | 0.13% | 00.0% | Unchanged |
| Janney Montgomery Scott LLC | 11,067 | $291.0K | 0.00% | 00.0% | Unchanged |
| Winton Group Ltd | 11,180 | $294.4K | 0.01% | +11,180 | New |
| Northwest & Ethical Investments L.P. | 12,044 | $319.6K | 0.01% | +2,014+20.1% | Added |
| China Universal Asset Management Co., Ltd. | 12,195 | $321.1K | 0.02% | −981−7.4% | Reduced |
| ProShare Advisors LLC | 12,387 | $326.2K | 0.00% | +1,186+10.6% | Added |
| Prudential Financial Inc | 12,755 | $335.8K | 0.00% | −20,635−61.8% | Reduced |
| Walleye Trading LLC | 13,252 | $348.9K | 0.01% | +13,252 | New |
| Walleye Capital LLC | 13,667 | $359.9K | 0.00% | +13,591+17,882.9% | Added |
| Police & Firemen's Retirement System of New Jersey | 13,702 | $360.8K | 0.00% | −503−3.5% | Reduced |
| Lazard Asset Management LLC | 13,776 | $362.7K | 0.00% | −1,532−10.0% | Reduced |
| Agf Management Ltd | 15,000 | $394.9K | 0.00% | +15,000 | New |
| State Board of Administration of Florida Retirement System | 15,340 | $403.9K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 17,371 | $457.4K | 0.00% | +4,000+29.9% | Added |
| Manufacturers Life Insurance Company, The | 17,433 | $459.0K | 0.00% | −141−0.8% | Reduced |
| Bank of Montreal | 17,468 | $459.9K | 0.00% | −10,174−36.8% | Reduced |
| SG Americas Securities, LLC | 17,557 | $462.0K | 0.00% | +3,933+28.9% | Added |
| HSBC Holdings PLC | 17,868 | $476.2K | 0.00% | −19,732−52.5% | Reduced |
| Janus Henderson Group PLC | 18,200 | $479.1K | 0.00% | 00.0% | Unchanged |
| Change Path, LLC | 18,264 | $480.9K | 0.01% | +18,264 | New |
| Vinva Investment Management Ltd | 12,216 | $483.9K | 0.01% | −2,378−16.3% | Reduced |
| Duncan Williams Asset Management, LLC | 22,095 | $510.6K | 0.13% | 00.0% | Unchanged |
| PSP Research LLC | 20,312 | $534.8K | 0.47% | +20,312 | New |
| Intech Investment Management LLC | 20,330 | $535.3K | 0.00% | +3,348+19.7% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 20,421 | $537.7K | 0.00% | −9,287−31.3% | Reduced |
| Seven Fleet Capital Management LP | 20,600 | $542.4K | 0.37% | +20,600 | New |
| Y-Intercept (Hong Kong) Ltd | 22,643 | $596.2K | 0.01% | +22,643 | New |
| Quadrature Capital Ltd | 23,017 | $606.0K | 0.01% | +23,017 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 23,109 | $608.5K | 0.00% | +164+0.7% | Added |
| BNP Paribas Arbitrage, SA | 23,298 | $613.4K | 0.00% | +7,838+50.7% | Added |