Zymeworks Inc.
ZYME- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001937653
No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Zymeworks Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 186
- +15 vs. Q4 2024
- Shares held
- 70.6M
- +5.43M (+8.3%) vs. Q4 2024
- Total value
- $840.9M
- −$113.0M (−11.8%) vs. Q4 2024
- New holders
- 32
- 60 more added
- Sold out
- 17
- 64 more reduced
3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 202 | $1.79B |
| Q1 2026 | 212 | $1.76B |
| Q4 2025 | 210 | $1.88B |
| Q3 2025 | 184 | $1.26B |
| Q2 2025 | 182 | $949.0M |
| Q1 2025 | 186 | $840.9M |
| Q4 2024 | 174 | $973.2M |
| Q3 2024 | 163 | $834.7M |
| Q2 2024 | 164 | $580.6M |
| Q1 2024 | 171 | $713.0M |
| Q4 2023 | 157 | $674.0M |
| Q3 2023 | 140 | $395.5M |
| Q2 2023 | 137 | $547.9M |
| Q1 2023 | 116 | $512.6M |
| Q4 2022 | 96 | $449.9M |
| Q3 2022 | 91 | $293.7M |
| Q2 2022 | 114 | $253.3M |
| Q1 2022 | 120 | $327.3M |
| Q4 2021 | 114 | $693.9M |
| Q3 2021 | 123 | $1.07B |
| Q2 2021 | 109 | $1.20B |
| Q1 2021 | 125 | $1.12B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Intech Investment Management LLC | 40,263 | $479.5K | 0.00% | +6,405+18.9% | Added |
| Citigroup Inc | 41,198 | $490.7K | 0.00% | −41,938−50.4% | Reduced |
| HighVista Strategies LLC | 41,607 | $495.5K | 0.19% | +41,607 | New |
| Prudential Financial Inc | 42,570 | $507.0K | 0.00% | +22,910+116.5% | Added |
| California State Teachers Retirement System | 43,783 | $521.5K | 0.00% | 00.0% | Unchanged |
| Virginia Retirement Systems Et Al | 44,175 | $526.1K | 0.00% | +44,175 | New |
| Victory Capital Management Inc | 44,270 | $527.3K | 0.00% | −7,310−14.2% | Reduced |
| Legal & General Group Plc | 46,790 | $557.3K | 0.00% | −292−0.6% | Reduced |
| AQR Capital Management LLC | 48,485 | $577.5K | 0.00% | +22,411+86.0% | Added |
| Envestnet Asset Management Inc | 49,512 | $589.7K | 0.00% | −4,578−8.5% | Reduced |
| ADAR1 Capital Management, LLC | 50,000 | $595.5K | 0.11% | +50,000 | New |
| Alliancebernstein L.P. | 50,030 | $595.9K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 56,771 | $676.0K | 0.00% | −4,155−6.8% | Reduced |
| Ritholtz Wealth Management | 60,494 | $720.5K | 0.02% | −13,972−18.8% | Reduced |
| Bank of America Corp | 62,131 | $740.0K | 0.00% | +30,431+96.0% | Added |
| D. E. Shaw & Co., Inc. | 63,099 | $751.5K | 0.00% | +42,259+202.8% | Added |
| Squarepoint Ops LLC | 63,602 | $757.5K | 0.00% | +63,602 | New |
| HRT Financial LP | 65,380 | $778.0K | 0.00% | −30,594−31.9% | Reduced |
| Stifel Financial Corp | 67,030 | $798.3K | 0.00% | +2,700+4.2% | Added |
| Acuta Capital Partners, LLC | 68,459 | $815.3K | 0.95% | +1,219+1.8% | Added |
| Fisher Asset Management, LLC | 71,974 | $857.2K | 0.00% | +8,374+13.2% | Added |
| Credit Agricole S A | 75,000 | $893.3K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 75,430 | $898.4K | 0.00% | −145,460−65.9% | Reduced |
| Invesco Ltd. | 78,206 | $931.4K | 0.00% | +8,824+12.7% | Added |
| Swiss National Bank | 80,100 | $954.0K | 0.00% | −10,100−11.2% | Reduced |
| Rhumbline Advisers | 82,738 | $985.4K | 0.00% | −21,138−20.3% | Reduced |
| Aquilo Capital Management, LLC | 84,482 | $1.01M | 2.71% | +84,482 | New |
| Voloridge Investment Management, LLC | 95,394 | $1.14M | 0.00% | +51,686+118.3% | Added |
| O'Shaughnessy Asset Management, LLC | 96,329 | $1.15M | 0.01% | −36,248−27.3% | Reduced |
| North Growth Management Ltd. | 97,000 | $1.15M | 0.24% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 98,165 | $1.17M | 0.00% | +71,383+266.5% | Added |
| Wells Fargo & Company | 100,309 | $1.19M | 0.00% | −63,749−38.9% | Reduced |
| Dark Forest Capital Management LP | 105,829 | $1.26M | 0.06% | +105,829 | New |
| Verition Fund Management LLC | 114,156 | $1.36M | 0.01% | +98,342+621.9% | Added |
| Raymond James Financial Inc | 116,711 | $1.39M | 0.00% | +56,069+92.5% | Added |
| Bank of New York Mellon Corp | 120,727 | $1.44M | 0.00% | +440.0% | Added |
| ExodusPoint Capital Management, LP | 133,320 | $1.59M | 0.02% | +133,320 | New |
| Charles Schwab Investment Management Inc | 133,639 | $1.59M | 0.00% | +2,333+1.8% | Added |
| Jane Street Group, LLC | 135,763 | $1.62M | 0.00% | +112,636+487.0% | Added |
| Kennedy Capital Management, Inc. | 136,319 | $1.62M | 0.04% | −3,634−2.6% | Reduced |
| Opaleye Management Inc. | 175,000 | $2.08M | 0.46% | +175,000 | New |
| Citadel Advisors LLC | 180,670 | $2.15M | 0.00% | +122,312+209.6% | Added |
| Federated Hermes, Inc. | 181,912 | $2.17M | 0.00% | +286+0.2% | Added |
| Wellington Management Group LLP | 182,246 | $2.17M | 0.00% | −36,852−16.8% | Reduced |
| Tejara Capital Ltd | 189,409 | $2.26M | 1.11% | +150,872+391.5% | Added |
| Nuveen, LLC | 198,812 | $2.37M | 0.00% | +198,812 | New |
| Goldman Sachs Group Inc | 200,047 | $2.38M | 0.00% | −49,913−20.0% | Reduced |
| Norges Bank | 201,700 | $2.40M | 0.00% | 00.0% | Unchanged |
| Picton Mahoney Asset Management | 208,029 | $2.48M | 0.08% | +1,460+0.7% | Added |
| UBS Group AG | 214,300 | $2.55M | 0.00% | +47,404+28.4% | Added |
| Trexquant Investment LP | 220,809 | $2.63M | 0.03% | +118,813+116.5% | Added |
| Hillsdale Investment Management Inc. | 236,925 | $2.82M | 0.14% | +6,900+3.0% | Added |
| Walleye Capital LLC | 247,959 | $2.95M | 0.03% | −204,845−45.2% | Reduced |
| Platinum Investment Management Ltd | 278,658 | $3.32M | 0.19% | −27,802−9.1% | Reduced |
| Silvercrest Asset Management Group LLC | 280,726 | $3.34M | 0.02% | −1,619−0.6% | Reduced |
| Millennium Management LLC | 295,606 | $3.52M | 0.00% | +295,606 | New |
| Schroder Investment Management Group | 321,949 | $3.98M | 0.00% | −15,212−4.5% | Reduced |
| Susquehanna International Group, LLP | 351,161 | $4.18M | 0.01% | +299,645+581.7% | Added |
| Empowered Funds, LLC | 360,044 | $4.29M | 0.06% | +7,291+2.1% | Added |
| Jupiter Asset Management Ltd | 369,499 | $4.40M | 0.04% | 00.0% | Unchanged |
| Northern Trust Corp | 386,923 | $4.61M | 0.00% | −7,907−2.0% | Reduced |
| Farallon Capital Management, L.L.C. | 400,000 | $4.76M | 0.03% | −929,974−69.9% | Reduced |
| Granahan Investment Management Inc | 407,589 | $4.85M | 0.24% | −3,531−0.9% | Reduced |
| Renaissance Technologies LLC | 450,600 | $5.37M | 0.01% | +164,900+57.7% | Added |
| Assenagon Asset Management S.A. | 495,067 | $5.90M | 0.01% | −147,184−22.9% | Reduced |
| Vestal Point Capital, LP | 500,000 | $5.96M | 0.43% | +315,000+170.3% | Added |
| Samsara BioCapital, LLC | 666,667 | $7.94M | 1.42% | −333,333−33.3% | Reduced |
| Geode Capital Management, LLC | 705,035 | $8.40M | 0.00% | +15,151+2.2% | Added |
| Bridgeway Capital Management, LLC | 766,944 | $9.13M | 0.23% | +7,291+1.0% | Added |
| Prosight Management, LP | 957,229 | $11.4M | 3.75% | +137,229+16.7% | Added |
| Dimensional Fund Advisors LP | 1,079,458 | $12.9M | 0.00% | +106,716+11.0% | Added |
| State Street Corp | 1,085,133 | $12.9M | 0.00% | +1720.0% | Added |
| Tang Capital Management LLC | 1,100,000 | $13.1M | 0.72% | 00.0% | Unchanged |
| Nextech Invest, Ltd. | 1,113,946 | $13.3M | 3.08% | +1,113,946 | New |
| Blackstone Group Inc. | 1,382,587 | $16.5M | 0.07% | +812,872+142.7% | Added |
| Deutsche Bank AG | 1,552,612 | $18.5M | 0.01% | +5,840+0.4% | Added |
| Vanguard Group Inc | 1,767,041 | $21.0M | 0.00% | −726,247−29.1% | Reduced |
| Perceptive Advisors LLC | 1,864,672 | $22.2M | 0.79% | −265,348−12.5% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 2,197,879 | $26.2M | 0.07% | +60,226+2.8% | Added |
| UBS Asset Management Americas Inc | 3,879,945 | $46.2M | 0.01% | +2,514,834+184.2% | Added |
| Morgan Stanley | 4,073,463 | $48.5M | 0.00% | −127,974−3.0% | Reduced |
| BlackRock, Inc. | 4,089,421 | $48.7M | 0.00% | −95,535−2.3% | Reduced |
| BVF Inc | 4,308,935 | $51.3M | 2.09% | 00.0% | Unchanged |
| Rubric Capital Management LP | 4,338,444 | $51.7M | 0.93% | +421,113+10.7% | Added |
| Redmile Group, LLC | 4,788,945 | $57.0M | 5.39% | −51,518−1.1% | Reduced |
| EcoR1 Capital, LLC | 17,259,548 | $205.6M | 12.23% | +2,231,469+14.8% | Added |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −330,127−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −230,970−100.0% | Sold out |
| Panagora Asset Management Inc | 0 | $0 | 0.00% | −214,338−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −121,526−100.0% | Sold out |
| Public Employees Retirement System of Ohio | 0 | $0 | 0.00% | −50,583−100.0% | Sold out |
| STRS Ohio | 0 | $0 | 0.00% | −49,000−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −48,612−100.0% | Sold out |
| Polar Asset Management Partners Inc. | 0 | $0 | 0.00% | −36,000−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −21,868−100.0% | Sold out |
| Monaco Asset Management SAM | 0 | $0 | 0.00% | −15,000−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −10,010−100.0% | Sold out |
| Compagnie Lombard Odier SCmA | 0 | $0 | 0.00% | −7,000−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −5,633−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −169−100.0% | Sold out |