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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Zymeworks Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
157
+18 vs. Q3 2023
Shares held
64.9M
+2.65M (+4.3%) vs. Q3 2023
Total value
$674.0M
+$279.2M (+70.7%) vs. Q3 2023
New holders
32
54 more added
Sold out
14
39 more reduced

1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 157 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ4 2023: $674.0M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2023.

Institutions holding ZYME in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Old Well Partners, LLC19,200$199.5K0.19%00.0%Unchanged
Janus Henderson Group PLC18,536$192.7K0.00%−11−0.1%Reduced
Cubist Systematic Strategies, LLC18,170$188.8K0.00%+18,170New
ExodusPoint Capital Management, LP18,006$187.0K0.00%+18,006New
Tower Research Capital LLC (TRC)17,092$177.6K0.00%+14,612+589.2%Added
State Board of Administration of Florida Retirement System15,340$159.4K0.00%00.0%Unchanged
Renaissance Technologies LLC14,700$153.0K0.00%−1,158−7.3%Reduced
Shell Asset Management Co14,392$150.0K0.01%+6,092+73.4%Added
ProShare Advisors LLC13,453$139.8K0.00%+13,453New
Price T Rowe Associates Inc13,313$139.0K0.00%+1,752+15.2%Added
Zurcher Kantonalbank (Zurich Cantonalbank)12,439$129.2K0.00%00.0%Unchanged
One Wealth Advisors, LLC12,121$125.9K0.02%00.0%Unchanged
HSBC Holdings PLC11,749$122.9K0.00%00.0%Unchanged
Shay Capital LLC11,339$117.8K0.05%−60,854−84.3%Reduced
State of Wyoming10,989$114.2K0.02%−8,657−44.1%Reduced
Point72 Middle East FZE10,437$108.4K0.01%+10,437New
Arizona State Retirement System10,429$108.4K0.00%+380+3.8%Added
Janney Montgomery Scott LLC10,267$107.0K0.00%−29,683−74.3%Reduced
Virtus ETF Advisers LLC10,264$106.6K0.07%−1,607−13.5%Reduced
Hunter Perkins Capital Management, LLC10,190$106.0K0.02%00.0%Unchanged
Fox Run Management, L.L.C.10,142$105.4K0.03%+10,142New
Vontobel Holding Ltd.10,000$103.9K0.00%−1,999−16.7%Reduced
Compagnie Lombard Odier SCmA10,000$103.9K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.8,100$84.2K0.02%+8,100New
AJOVista, LLC6,362$66.1K0.08%+6,362New
Ameritas Investment Partners, Inc.5,616$58.4K0.00%+1,208+27.4%Added
New York State Teachers Retirement System4,781$50.0K0.00%+4,781New
Amalgamated Bank4,655$48.0K0.00%−536−10.3%Reduced
Gladius Capital Management LP4,491$46.7K0.03%+551+14.0%Added
DekaBank Deutsche Girozentrale3,843$40.0K0.00%−9,191−70.5%Reduced
Virtus Fund Advisers, LLC3,100$32.2K0.20%+3,100New
Metropolitan Life Insurance Co2,995$31.1K0.00%00.0%Unchanged
Plato Investment Management Ltd2,088$21.7K0.03%+2,088New
US Bancorp1,535$15.9K0.00%+137+9.8%Added
Cutler Group LP1,400$14.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.1,037$10.8K0.00%+400+62.8%Added
Global Retirement Partners, LLC905$9.54K0.00%00.0%Unchanged
Stonehage Fleming Financial Services Holdings Ltd550$5.71K0.00%00.0%Unchanged
Robeco Institutional Asset Management B.V.536$5.57K0.00%+536New
Federated Hermes, Inc.398$4.13K0.00%+398New
Parallel Advisors, LLC329$3.42K0.00%+13+4.1%Added
Lindbrook Capital, LLC318$3.30K0.00%+318New
Daiwa Securities Group Inc.286$3.00K0.00%+286New
HighMark Wealth Management LLC280$2.91K0.00%00.0%Unchanged
Security National Bank135$1.40K0.00%+135New
TD Waterhouse Canada Inc.96$1.39K0.00%00.0%Unchanged
Eagle Bay Advisors LLC110$1.14K0.00%00.0%Unchanged
Frazier Financial Advisors, LLC107$1.11K0.00%+107New
GAMMA Investing LLC57$6180.00%+57New
Steward Partners Investment Advisory, LLC53$5510.00%00.0%Unchanged
Nisa Investment Advisors, LLC35$3640.00%−25−41.7%Reduced
Allworth Financial LP34$3540.00%+34New
Farther Finance Advisors, LLC25$2600.00%+25New
Toronto Dominion Bank16$1660.00%00.0%Unchanged
The PNC Financial Services Group, Inc.9$940.00%+9New
Asset Dedication, LLC47$00.00%00.0%Unchanged
CWM, LLC3$00.00%−37−92.5%Reduced
Point72 Asset Management, L.P.0$00.00%−295,114−100.0%Sold out
Mariner, LLC0$00.00%−162,550−100.0%Sold out
Clearline Capital LP0$00.00%−153,136−100.0%Sold out
Prosight Management, LP0$00.00%−106,405−100.0%Sold out
Wela Strategies, Inc.0$00.00%−70,255−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−65,068−100.0%Sold out
683 Capital Management, LLC0$00.00%−64,900−100.0%Sold out
Bank of Montreal0$00.00%−36,634−100.0%Sold out
Trexquant Investment LP0$00.00%−36,486−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−18,052−100.0%Sold out
Walleye Capital LLC0$00.00%−11,468−100.0%Sold out
Simplex Trading, LLC0$00.00%−11,143−100.0%Sold out
Group One Trading, L.P.0$00.00%−7,327−100.0%Sold out
Comerica Bank0$00.00%−77−100.0%Sold out
Virginia Retirement Systems Et Al––––Not filed