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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Zymeworks Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
157
+18 vs. Q3 2023
Shares held
64.9M
+2.65M (+4.3%) vs. Q3 2023
Total value
$674.0M
+$279.2M (+70.7%) vs. Q3 2023
New holders
32
54 more added
Sold out
14
39 more reduced

1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 157 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ4 2023: $674.0M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q3 2023.

Institutions holding ZYME in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Stifel Financial Corp70,025$727.6K0.00%+7,750+12.4%Added
Swiss National Bank73,600$764.7K0.00%−4,000−5.2%Reduced
Susquehanna International Group, LLP76,740$797.3K0.00%+11,219+17.1%Added
Rhumbline Advisers77,597$806.2K0.00%+5,490+7.6%Added
Connor, Clark & Lunn Investment Management Ltd.82,474$856.9K0.00%+64,552+360.2%Added
Royal Bank of Canada85,187$885.0K0.00%+3,433+4.2%Added
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main85,878$892.3K0.00%00.0%Unchanged
SummerHaven Investment Management, LLC87,509$909.2K0.58%+1,199+1.4%Added
Barclays PLC93,329$969.7K0.00%+93,329New
Bank of America Corp94,643$983.3K0.00%+4,943+5.5%Added
North Growth Management Ltd.97,000$1.01M0.21%00.0%Unchanged
Ameriprise Financial Inc122,926$1.28M0.00%+122,926New
Charles Schwab Investment Management Inc125,491$1.30M0.00%+3,625+3.0%Added
UBS Oconnor LLC136,313$1.42M0.04%−208,159−60.4%Reduced
Advantage Alpha Capital Partners LP136,819$1.42M0.27%+136,819New
Kennedy Capital Management, Inc.156,034$1.62M0.04%−2,641−1.7%Reduced
O'Shaughnessy Asset Management, LLC168,700$1.75M0.02%+44,152+35.4%Added
Citadel Advisors LLC173,573$1.80M0.00%+136,567+369.0%Added
Nuveen Asset Management, LLC194,982$2.03M0.00%−835−0.4%Reduced
Goldman Sachs Group Inc200,621$2.08M0.00%+32,050+19.0%Added
Norges Bank201,700$2.10M0.00%+201,700New
Wellington Management Group LLP205,246$2.13M0.00%+48,564+31.0%Added
Allspring Global Investments Holdings, LLC227,625$2.37M0.00%+38,181+20.2%Added
Prudential Financial Inc236,260$2.45M0.00%+15,550+7.0%Added
Wells Fargo & Company238,246$2.48M0.00%+46,616+24.3%Added
Tejara Capital Ltd255,575$2.66M1.11%−32,518−11.3%Reduced
Empowered Funds, LLC273,416$2.84M0.07%+24,661+9.9%Added
Bank of New York Mellon Corp276,899$2.88M0.00%+137,484+98.6%Added
Dimensional Fund Advisors LP342,215$3.56M0.00%−6,984−2.0%Reduced
Monaco Asset Management SAM350,000$3.64M1.40%−66,275−15.9%Reduced
Picton Mahoney Asset Management356,906$3.71M0.17%−1,912−0.5%Reduced
Arrowstreet Capital, Limited Partnership367,018$3.81M0.00%−104,987−22.2%Reduced
Jacobs Levy Equity Management, Inc368,041$3.82M0.02%+304,040+475.1%Added
Silvercrest Asset Management Group LLC375,848$3.91M0.03%00.0%Unchanged
Platinum Investment Management Ltd409,839$4.26M0.17%00.0%Unchanged
Northern Trust Corp417,146$4.33M0.00%−2,721−0.6%Reduced
Jupiter Asset Management Ltd495,582$5.15M0.05%+20,858+4.4%Added
Geode Capital Management, LLC639,672$6.65M0.00%+40,209+6.7%Added
Bridgeway Capital Management, LLC680,316$7.07M0.15%+24,661+3.8%Added
AQR Capital Management LLC686,190$7.13M0.01%−113,489−14.2%Reduced
Granahan Investment Management Inc700,558$7.28M0.24%−20,623−2.9%Reduced
Deutsche Bank AG888,635$9.23M0.00%+773,782+673.7%Added
State Street Corp1,007,812$10.5M0.00%+70,710+7.5%Added
Perceptive Advisors LLC1,074,807$11.2M0.25%−371,316−25.7%Reduced
Tang Capital Management LLC1,100,000$11.4M1.06%00.0%Unchanged
Acadian Asset Management LLC1,254,021$13.0M0.05%+428,033+51.8%Added
Samsara BioCapital, LLC1,458,875$15.2M2.36%00.0%Unchanged
Farallon Capital Management, L.L.C.1,756,000$18.2M0.11%−244,000−12.2%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,771,776$18.4M0.05%+213,525+13.7%Added
Credit Suisse AG2,303,621$24.0M0.02%−185,555−7.5%Reduced
Vanguard Group Inc2,394,712$24.9M0.00%+10,726+0.4%Added
Rubric Capital Management LP3,475,384$36.1M1.35%+823,990+31.1%Added
BlackRock Inc.3,923,328$40.8M0.00%+304,353+8.4%Added
Morgan Stanley4,861,286$50.5M0.00%+376,568+8.4%Added
Redmile Group, LLC5,790,230$60.2M2.15%+129,000+2.3%Added
BVF Inc5,870,000$61.0M1.53%00.0%Unchanged
EcoR1 Capital, LLC13,437,473$139.6M3.63%00.0%Unchanged
Point72 Asset Management, L.P.0$00.00%−295,114−100.0%Sold out
Mariner, LLC0$00.00%−162,550−100.0%Sold out
Clearline Capital LP0$00.00%−153,136−100.0%Sold out
Prosight Management, LP0$00.00%−106,405−100.0%Sold out
Wela Strategies, Inc.0$00.00%−70,255−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−65,068−100.0%Sold out
683 Capital Management, LLC0$00.00%−64,900−100.0%Sold out
Bank of Montreal0$00.00%−36,634−100.0%Sold out
Trexquant Investment LP0$00.00%−36,486−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−18,052−100.0%Sold out
Walleye Capital LLC0$00.00%−11,468−100.0%Sold out
Simplex Trading, LLC0$00.00%−11,143−100.0%Sold out
Group One Trading, L.P.0$00.00%−7,327−100.0%Sold out
Comerica Bank0$00.00%−77−100.0%Sold out
Virginia Retirement Systems Et Al––––Not filed