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Zymeworks Inc.

ZYME
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001937653

No open-market purchases or sales by Zymeworks Inc. insiders were filed in the last 90 days; 202 institutions reported holding it in 13F filings for Q2 2026, worth $1.79B in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Zymeworks Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
116
+21 vs. Q4 2022
Shares held
56.7M
−535.1K (−0.9%) vs. Q4 2022
Total value
$512.6M
+$62.8M (+14.0%) vs. Q4 2022
New holders
40
36 more added
Sold out
19
27 more reduced

1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZYME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 116 institutions
Q1 2021: 125 institutionsQ2 2021: 109 institutionsQ3 2021: 123 institutionsQ4 2021: 114 institutionsQ1 2022: 120 institutionsQ2 2022: 114 institutionsQ3 2022: 91 institutionsQ4 2022: 96 institutionsQ1 2023: 116 institutionsQ2 2023: 137 institutionsQ3 2023: 140 institutionsQ4 2023: 157 institutionsQ1 2024: 171 institutionsQ2 2024: 164 institutionsQ3 2024: 163 institutionsQ4 2024: 174 institutionsQ1 2025: 186 institutionsQ2 2025: 182 institutionsQ3 2025: 184 institutionsQ4 2025: 210 institutionsQ1 2026: 212 institutionsQ2 2026: 202 institutions
Value heldQ1 2023: $512.6M
Q1 2021: $1.12BQ2 2021: $1.20BQ3 2021: $1.07BQ4 2021: $693.9MQ1 2022: $327.3MQ2 2022: $253.3MQ3 2022: $293.7MQ4 2022: $449.9MQ1 2023: $512.6MQ2 2023: $547.9MQ3 2023: $395.5MQ4 2023: $674.0MQ1 2024: $713.0MQ2 2024: $580.6MQ3 2024: $834.7MQ4 2024: $973.2MQ1 2025: $840.9MQ2 2025: $949.0MQ3 2025: $1.26BQ4 2025: $1.88BQ1 2026: $1.76BQ2 2026: $1.79B
Institutions holding ZYME and their total value by quarter
QuarterHoldersValue
Q2 2026202$1.79B
Q1 2026212$1.76B
Q4 2025210$1.88B
Q3 2025184$1.26B
Q2 2025182$949.0M
Q1 2025186$840.9M
Q4 2024174$973.2M
Q3 2024163$834.7M
Q2 2024164$580.6M
Q1 2024171$713.0M
Q4 2023157$674.0M
Q3 2023140$395.5M
Q2 2023137$547.9M
Q1 2023116$512.6M
Q4 202296$449.9M
Q3 202291$293.7M
Q2 2022114$253.3M
Q1 2022120$327.3M
Q4 2021114$693.9M
Q3 2021123$1.07B
Q2 2021109$1.20B
Q1 2021125$1.12B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Zymeworks Inc.; share changes are against Q4 2022.

Institutions holding ZYME in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Frazier Life Sciences Management, L.P.610,000$5.51M0.40%00.0%Unchanged
Millennium Management LLC649,183$5.87M0.01%+533,661+462.0%Added
Granahan Investment Management Inc650,389$5.88M0.18%−88,059−11.9%Reduced
BlackRock Inc.751,573$6.79M0.00%+75,166+11.1%Added
Tang Capital Management LLC1,100,000$9.94M1.48%+700,000+175.0%Added
Samsara BioCapital, LLC1,620,687$14.7M3.03%00.0%Unchanged
Farallon Capital Management, L.L.C.2,000,000$18.1M0.11%+500,000+33.3%Added
Vanguard Group Inc2,040,149$18.4M0.00%−496,246−19.6%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.2,306,472$20.9M0.07%+14,665+0.6%Added
Credit Suisse AG2,485,285$22.5M0.02%+46,190+1.9%Added
Rubric Capital Management LP2,854,732$25.8M1.03%−163,485−5.4%Reduced
Perceptive Advisors LLC3,378,498$30.5M0.90%−1,132,777−25.1%Reduced
Morgan Stanley5,563,301$50.3M0.01%−10,079−0.2%Reduced
BVF Inc5,870,000$53.1M1.94%00.0%Unchanged
Redmile Group, LLC6,067,918$54.9M2.38%−108,000−1.7%Reduced
EcoR1 Capital, LLC10,087,473$91.2M2.94%+2,518,900+33.3%Added
Baker Bros. Advisors LP0$00.00%−1,708,472−100.0%Sold out
Brookfield Asset Management Inc.0$00.00%−741,186−100.0%Sold out
Sessa Capital IM, L.P.0$00.00%−740,878−100.0%Sold out
Woodline Partners LP0$00.00%−600,403−100.0%Sold out
Artal Group S.A.0$00.00%−450,000−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−369,187−100.0%Sold out
Sectoral Asset Management Inc0$00.00%−192,124−100.0%Sold out
Ci Investments Inc.0$00.00%−147,170−100.0%Sold out
Candriam Luxembourg S.C.A.0$00.00%−120,305−100.0%Sold out
Thrivent Financial for Lutherans0$00.00%−117,092−100.0%Sold out
AlphaCentric Advisors LLC0$00.00%−52,500−100.0%Sold out
Invesco Ltd.0$00.00%−51,180−100.0%Sold out
Parallax Volatility Advisers, L.P.0$00.00%−30,000−100.0%Sold out
Group One Trading, L.P.0$00.00%−27,939−100.0%Sold out
Walleye Trading LLC0$00.00%−24,378−100.0%Sold out
Forefront Wealth Management Inc.0$00.00%−13,400−100.0%Sold out
Alpine Global Management, LLC0$00.00%−13,046−100.0%Sold out
Rockefeller Capital Management L.P.0$00.00%−1,500−100.0%Sold out
GWM Advisors LLC0$00.00%−100−100.0%Sold out
CoreCap Advisors, LLC––––Not filed