Wave Life Sciences, Inc.
WVE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001631574
In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in Wave Life Sciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 219
- +35 vs. Q3 2025
- Shares held
- 182.7M
- +39.1M (+27.3%) vs. Q3 2025
- Total value
- $3.11B
- +$2.06B (+195.7%) vs. Q3 2025
- New holders
- 73
- 79 more added
- Sold out
- 38
- 47 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 239 | $1.06B |
| Q1 2026 | 232 | $1.25B |
| Q4 2025 | 219 | $3.11B |
| Q3 2025 | 189 | $1.05B |
| Q2 2025 | 177 | $903.1M |
| Q1 2025 | 197 | $1.06B |
| Q4 2024 | 184 | $1.59B |
| Q3 2024 | 162 | $986.1M |
| Q2 2024 | 144 | $474.4M |
| Q1 2024 | 132 | $572.3M |
| Q4 2023 | 115 | $468.0M |
| Q3 2023 | 85 | $417.4M |
| Q2 2023 | 81 | $262.7M |
| Q1 2023 | 73 | $303.5M |
| Q4 2022 | 75 | $476.9M |
| Q3 2022 | 61 | $242.8M |
| Q2 2022 | 60 | $220.3M |
| Q1 2022 | 82 | $95.4M |
| Q4 2021 | 90 | $148.5M |
| Q3 2021 | 88 | $183.5M |
| Q2 2021 | 87 | $246.7M |
| Q1 2021 | 102 | $214.8M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| GSK plc | 18,245,691 | $310.2M | 38.82% | +18,245,691 | New |
| Ra Capital Management, L.P. | 18,203,009 | $309.5M | 3.17% | +1,0000.0% | Added |
| FMR LLC | 15,135,983 | $257.3M | 0.01% | +10,005,609+195.0% | Added |
| BlackRock, Inc. | 12,648,907 | $215.0M | 0.00% | +2,218,094+21.3% | Added |
| Adage Capital Partners GP, L.L.C. | 9,786,061 | $166.4M | 0.25% | −4,781,723−32.8% | Reduced |
| Maverick Capital LtdSuperinvestorMaverick Capital | 9,280,237 | $157.8M | 1.69% | +888,381+10.6% | Added |
| Price T Rowe Associates Inc | 7,407,372 | $125.9M | 0.01% | +3,362,880+83.1% | Added |
| Darwin Global Management, Ltd. | 7,298,421 | $125.2M | 2.53% | +7,298,421 | New |
| Driehaus Capital Management LLC | 6,581,067 | $111.9M | 0.76% | +283,007+4.5% | Added |
| M28 Capital Management LP | 5,664,548 | $96.3M | 70.00% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 4,744,520 | $80.7M | 0.13% | +993,827+26.5% | Added |
| Primecap Management Co | 4,095,282 | $69.6M | 0.05% | +2,196,632+115.7% | Added |
| 683 Capital Management, LLC | 4,015,000 | $68.3M | 5.68% | −135,000−3.3% | Reduced |
| Vanguard Group Inc | 3,573,746 | $60.8M | 0.00% | +433,910+13.8% | Added |
| Geode Capital Management, LLC | 3,170,110 | $53.9M | 0.00% | +251,740+8.6% | Added |
| State Street Corp | 2,996,084 | $50.9M | 0.00% | +149,718+5.3% | Added |
| Goldman Sachs Group Inc | 2,854,082 | $48.5M | 0.01% | +728,945+34.3% | Added |
| Affinity Asset Advisors, LLC | 2,700,000 | $45.9M | 3.30% | +600,000+28.6% | Added |
| Emerald Advisers, LLC | 2,455,089 | $41.7M | 1.29% | −541,811−18.1% | Reduced |
| Siren, L.L.C. | 2,450,000 | $41.6M | 1.24% | −1,246,322−33.7% | Reduced |
| Kynam Capital Management, LP | 2,169,105 | $36.9M | 2.40% | −2,390,948−52.4% | Reduced |
| Loomis Sayles & Co L P | 2,040,223 | $34.7M | 0.04% | −865,243−29.8% | Reduced |
| Pfizer Inc | 1,875,000 | $31.9M | 13.48% | 00.0% | Unchanged |
| First Light Asset Management, LLC | 1,853,851 | $31.5M | 2.41% | +1,853,851 | New |
| Bellevue Group AG | 1,490,518 | $25.3M | 0.48% | −2,603,940−63.6% | Reduced |
| Emerald Mutual Fund Advisers Trust | 1,414,665 | $24.0M | 1.17% | −351,397−19.9% | Reduced |
| RTW Investments, LP | 1,350,000 | $22.9M | 0.23% | +450,000+50.0% | Added |
| Charles Schwab Investment Management Inc | 1,191,361 | $20.3M | 0.00% | +192,989+19.3% | Added |
| Northern Trust Corp | 1,033,068 | $17.6M | 0.00% | +21,318+2.1% | Added |
| Schroder Investment Management Group | 1,005,984 | $17.3M | 0.01% | +450,440+81.1% | Added |
| JPMorgan Chase & Co | 892,886 | $15.2M | 0.00% | +32,745+3.8% | Added |
| Squarepoint Ops LLC | 883,586 | $15.0M | 0.03% | +609,995+223.0% | Added |
| Pictet Asset Management Holding SA | 805,901 | $13.8M | 0.01% | +790,175+5,024.6% | Added |
| Citadel Advisors LLC | 789,964 | $13.4M | 0.01% | +789,964 | New |
| Two Sigma Investments, LP | 749,448 | $12.7M | 0.02% | +186,444+33.1% | Added |
| Voloridge Investment Management, LLC | 722,237 | $12.3M | 0.04% | +722,237 | New |
| Tang Capital Management LLC | 600,000 | $10.2M | 0.50% | +600,000 | New |
| Millennium Management LLC | 584,633 | $9.94M | 0.01% | +193,884+49.6% | Added |
| Eventide Asset Management, LLC | 500,000 | $8.50M | 0.13% | +500,000 | New |
| Kennedy Capital Management, Inc. | 492,437 | $8.37M | 0.18% | −48,000−8.9% | Reduced |
| Elmind Capital, LP | 447,846 | $7.61M | 2.25% | +447,846 | New |
| Exome Asset Management LLC | 421,488 | $7.17M | 3.54% | +421,488 | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 411,494 | $7.00M | 0.01% | +42,789+11.6% | Added |
| Morgan Stanley | 409,663 | $6.96M | 0.00% | −97,627−19.2% | Reduced |
| Sphera Funds Management Ltd. | 408,166 | $6.94M | 1.45% | +358,166+716.3% | Added |
| Ameriprise Financial Inc | 398,416 | $6.77M | 0.00% | +290,551+269.4% | Added |
| F/M Investments LLC | 395,894 | $6.73M | 0.26% | +77,807+24.5% | Added |
| Trexquant Investment LP | 391,111 | $6.65M | 0.06% | +391,111 | New |
| Susquehanna International Group, LLP | 378,987 | $6.44M | 0.01% | +182,707+93.1% | Added |
| Walleye Capital LLC | 378,823 | $6.44M | 0.04% | −351,816−48.2% | Reduced |
| Wellington Management Group LLP | 365,235 | $6.21M | 0.00% | −64,384−15.0% | Reduced |
| Boone Capital Management LLC | 352,144 | $5.99M | 1.88% | +352,144 | New |
| Woodline Partners LP | 350,531 | $5.96M | 0.02% | +350,531 | New |
| Baker Bros. Advisors LP | 344,063 | $5.85M | 0.03% | 00.0% | Unchanged |
| Jacobs Levy Equity Management, Inc | 338,546 | $5.76M | 0.02% | +338,546 | New |
| Nuveen, LLC | 332,735 | $5.66M | 0.00% | +83,266+33.4% | Added |
| Jain Global LLC | 328,145 | $5.58M | 0.05% | +328,145 | New |
| Bank of New York Mellon Corp | 321,445 | $5.46M | 0.00% | +23,589+7.9% | Added |
| Jump Financial, LLC | 313,509 | $5.33M | 0.07% | +313,509 | New |
| Newtyn Management, LLC | 300,000 | $5.10M | 0.54% | 00.0% | Unchanged |
| HRT Financial LP | 299,718 | $5.09M | 0.02% | +299,718 | New |
| Barclays PLC | 276,781 | $4.71M | 0.00% | +3,907+1.4% | Added |
| Moody Aldrich Partners LLC | 274,425 | $4.67M | 0.87% | −76,123−21.7% | Reduced |
| UBS Group AG | 268,723 | $4.57M | 0.00% | −436,885−61.9% | Reduced |
| D. E. Shaw & Co., Inc. | 266,132 | $4.52M | 0.00% | +266,132 | New |
| TD Asset Management Inc | 252,160 | $4.29M | 0.00% | +109,752+77.1% | Added |
| EAM Investors, LLC | 248,815 | $4.23M | 0.47% | +248,815 | New |
| Renaissance Technologies LLC | 236,420 | $4.02M | 0.01% | +236,420 | New |
| Boothbay Fund Management, LLC | 234,799 | $3.99M | 0.10% | +113,637+93.8% | Added |
| Platinum Investment Management Ltd | 230,687 | $3.92M | 0.91% | −37,107−13.9% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 230,512 | $3.92M | 0.06% | −74,862−24.5% | Reduced |
| Swiss National Bank | 219,700 | $3.73M | 0.00% | +8,700+4.1% | Added |
| Nomura Asset Management International Inc. | 203,744 | $3.46M | 0.01% | +203,744 | New |
| AQR Capital Management LLC | 202,721 | $3.45M | 0.00% | +192,023+1,794.9% | Added |
| Wells Fargo & Company | 200,890 | $3.42M | 0.00% | +127,079+172.2% | Added |
| Privium Fund Management B.V. | 193,010 | $3.28M | 0.60% | +23,010+13.5% | Added |
| Manufacturers Life Insurance Company, The | 182,728 | $3.13M | 0.00% | +57,369+45.8% | Added |
| Bank of America Corp | 182,855 | $3.11M | 0.00% | −482,295−72.5% | Reduced |
| Invesco Ltd. | 179,932 | $3.06M | 0.00% | +38,806+27.5% | Added |
| Squadron Capital Management LLC | 175,000 | $2.98M | 1.33% | +175,000 | New |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 173,000 | $2.94M | 0.07% | +173,000 | New |
| Principal Financial Group Inc | 170,170 | $2.89M | 0.00% | +170,170 | New |
| UBS Asset Management Americas Inc | 164,985 | $2.80M | 0.00% | +164,985 | New |
| Sofinnova Investments, Inc. | 158,182 | $2.69M | 0.12% | −12,761−7.5% | Reduced |
| Burkehill Global Management, LP | 150,000 | $2.55M | 0.17% | +150,000 | New |
| Rhumbline Advisers | 141,895 | $2.41M | 0.00% | −17,278−10.9% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 134,558 | $2.29M | 0.00% | +282+0.2% | Added |
| Algert Global LLC | 122,470 | $2.08M | 0.03% | +122,470 | New |
| Voya Investment Management LLC | 112,875 | $1.92M | 0.00% | −145,136−56.3% | Reduced |
| Alliancebernstein L.P. | 112,030 | $1.90M | 0.00% | +19,200+20.7% | Added |
| Raymond James Financial Inc | 111,170 | $1.89M | 0.00% | +95,483+608.7% | Added |
| Jane Street Group, LLC | 110,924 | $1.89M | 0.00% | −508,717−82.1% | Reduced |
| California State Teachers Retirement System | 107,680 | $1.83M | 0.00% | +9,185+9.3% | Added |
| James J. Burns & Company, LLC | 105,802 | $1.80M | 0.25% | 00.0% | Unchanged |
| Itau Unibanco Holding S.A. | 102,000 | $1.75M | 0.04% | +102,000 | New |
| LMR Partners LLP | 100,000 | $1.70M | 0.02% | +100,000 | New |
| Seven Grand Managers, LLC | 100,000 | $1.70M | 0.13% | +100,000 | New |
| Deutsche Bank AG | 95,706 | $1.63M | 0.00% | +1,441+1.5% | Added |
| Dark Forest Capital Management LP | 95,068 | $1.62M | 0.07% | −167,509−63.8% | Reduced |
| Legal & General Group Plc | 93,985 | $1.60M | 0.00% | −7,931−7.8% | Reduced |