Wave Life Sciences, Inc.
WVE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001631574
In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q3 2025
Institutional positions in Wave Life Sciences, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 189
- +14 vs. Q2 2025
- Shares held
- 143.7M
- +4.85M (+3.5%) vs. Q2 2025
- Total value
- $1.05B
- +$149.2M (+16.5%) vs. Q2 2025
- New holders
- 32
- 61 more added
- Sold out
- 18
- 62 more reduced
2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 239 | $1.06B |
| Q1 2026 | 232 | $1.25B |
| Q4 2025 | 219 | $3.11B |
| Q3 2025 | 189 | $1.05B |
| Q2 2025 | 177 | $903.1M |
| Q1 2025 | 197 | $1.06B |
| Q4 2024 | 184 | $1.59B |
| Q3 2024 | 162 | $986.1M |
| Q2 2024 | 144 | $474.4M |
| Q1 2024 | 132 | $572.3M |
| Q4 2023 | 115 | $468.0M |
| Q3 2023 | 85 | $417.4M |
| Q2 2023 | 81 | $262.7M |
| Q1 2023 | 73 | $303.5M |
| Q4 2022 | 75 | $476.9M |
| Q3 2022 | 61 | $242.8M |
| Q2 2022 | 60 | $220.3M |
| Q1 2022 | 82 | $95.4M |
| Q4 2021 | 90 | $148.5M |
| Q3 2021 | 88 | $183.5M |
| Q2 2021 | 87 | $246.7M |
| Q1 2021 | 102 | $214.8M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 18,202,009 | $133.2M | 1.64% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 14,567,784 | $106.6M | 0.17% | −448,716−3.0% | Reduced |
| BlackRock, Inc. | 10,430,813 | $76.4M | 0.00% | +47,097+0.5% | Added |
| Maverick Capital LtdSuperinvestorMaverick Capital | 8,391,856 | $61.4M | 0.82% | +130,173+1.6% | Added |
| Driehaus Capital Management LLC | 6,298,060 | $46.1M | 0.33% | −233,459−3.6% | Reduced |
| M28 Capital Management LP | 5,664,548 | $41.5M | 60.97% | 00.0% | Unchanged |
| FMR LLC | 5,130,374 | $37.6M | 0.00% | +4,511,237+728.6% | Added |
| Kynam Capital Management, LP | 4,560,053 | $33.4M | 2.49% | 00.0% | Unchanged |
| 683 Capital Management, LLC | 4,150,000 | $30.4M | 2.76% | +50,000+1.2% | Added |
| Bellevue Group AG | 4,094,458 | $30.0M | 0.62% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 4,044,492 | $29.6M | 0.00% | −1,145,911−22.1% | Reduced |
| Federated Hermes, Inc. | 3,750,693 | $27.5M | 0.05% | +3,750,140+678,144.7% | Added |
| Siren, L.L.C. | 3,696,322 | $27.1M | 1.06% | 00.0% | Unchanged |
| Vanguard Group Inc | 3,139,836 | $23.0M | 0.00% | −337,241−9.7% | Reduced |
| Emerald Advisers, LLC | 2,996,900 | $21.9M | 0.70% | −260,219−8.0% | Reduced |
| Geode Capital Management, LLC | 2,918,370 | $21.4M | 0.00% | +158,989+5.8% | Added |
| Loomis Sayles & Co L P | 2,905,466 | $21.3M | 0.03% | −390,234−11.8% | Reduced |
| State Street Corp | 2,846,366 | $20.8M | 0.00% | +89,611+3.3% | Added |
| Goldman Sachs Group Inc | 2,125,137 | $15.6M | 0.00% | +1,118,056+111.0% | Added |
| StemPoint Capital LP | 2,110,152 | $15.4M | 3.11% | +1,209,814+134.4% | Added |
| Affinity Asset Advisors, LLC | 2,100,000 | $15.4M | 1.43% | +99,692+5.0% | Added |
| Primecap Management Co | 1,898,650 | $13.9M | 0.01% | −567,200−23.0% | Reduced |
| Pfizer Inc | 1,875,000 | $13.7M | 3.14% | 00.0% | Unchanged |
| Emerald Mutual Fund Advisers Trust | 1,766,062 | $12.9M | 0.67% | −171,427−8.8% | Reduced |
| MPM Oncology Impact Management LP | 1,505,262 | $11.0M | 1.80% | 00.0% | Unchanged |
| Artisan Partners Limited Partnership | 1,232,926 | $9.03M | 0.01% | −1,031,909−45.6% | Reduced |
| Polar Capital Holdings Plc | 1,062,276 | $7.78M | 0.04% | +58,776+5.9% | Added |
| Northern Trust Corp | 1,011,750 | $7.41M | 0.00% | +2,968+0.3% | Added |
| Charles Schwab Investment Management Inc | 998,372 | $7.31M | 0.00% | −12,286−1.2% | Reduced |
| RTW Investments, LP | 900,000 | $6.59M | 0.08% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 860,141 | $6.30M | 0.00% | −708,874−45.2% | Reduced |
| Walleye Capital LLC | 730,639 | $5.35M | 0.04% | +262,752+56.2% | Added |
| UBS Group AG | 705,608 | $5.17M | 0.00% | +98,336+16.2% | Added |
| Bank of America Corp | 665,150 | $4.87M | 0.00% | +19,590+3.0% | Added |
| Point72 Asset Management, L.P. | 663,967 | $4.86M | 0.01% | +663,967 | New |
| Jane Street Group, LLC | 619,641 | $4.54M | 0.01% | +619,641 | New |
| Two Sigma Investments, LP | 563,004 | $4.12M | 0.01% | +319,837+131.5% | Added |
| Schroder Investment Management Group | 555,544 | $3.96M | 0.00% | −65,834−10.6% | Reduced |
| Kennedy Capital Management, Inc. | 540,437 | $3.96M | 0.09% | +506,437+1,489.5% | Added |
| Morgan Stanley | 507,290 | $3.71M | 0.00% | −1,036,748−67.1% | Reduced |
| Wellington Management Group LLP | 429,619 | $3.14M | 0.00% | +131,732+44.2% | Added |
| Millennium Management LLC | 390,749 | $2.86M | 0.00% | −301,666−43.6% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 368,705 | $2.70M | 0.00% | +10,276+2.9% | Added |
| Moody Aldrich Partners LLC | 350,548 | $2.57M | 0.49% | −71,304−16.9% | Reduced |
| Baker Bros. Advisors LP | 344,063 | $2.52M | 0.02% | 00.0% | Unchanged |
| F/M Investments LLC | 318,087 | $2.33M | 0.09% | +74,410+30.5% | Added |
| Ensign Peak Advisors, Inc | 313,307 | $2.29M | 0.00% | 00.0% | Unchanged |
| Susquehanna Portfolio Strategies, LLC | 305,374 | $2.24M | 0.04% | +20,288+7.1% | Added |
| Newtyn Management, LLC | 300,000 | $2.20M | 0.27% | −100,000−25.0% | Reduced |
| Bank of New York Mellon Corp | 297,856 | $2.18M | 0.00% | +8,574+3.0% | Added |
| Avidity Partners Management LP | 297,500 | $2.18M | 0.50% | +297,500 | New |
| Squarepoint Ops LLC | 273,591 | $2.00M | 0.00% | +227,437+492.8% | Added |
| Barclays PLC | 272,874 | $2.00M | 0.00% | −300,313−52.4% | Reduced |
| Platinum Investment Management Ltd | 267,794 | $1.96M | 0.13% | −87,559−24.6% | Reduced |
| Dark Forest Capital Management LP | 262,577 | $1.92M | 0.07% | −18,188−6.5% | Reduced |
| Voya Investment Management LLC | 258,011 | $1.89M | 0.00% | +227,167+736.5% | Added |
| Two Sigma Advisers, LP | 251,700 | $1.84M | 0.00% | +159,400+172.7% | Added |
| Nuveen, LLC | 249,469 | $1.83M | 0.00% | 00.0% | Unchanged |
| Swiss National Bank | 211,000 | $1.54M | 0.00% | +5,800+2.8% | Added |
| Susquehanna International Group, LLP | 196,280 | $1.44M | 0.00% | −28,146−12.5% | Reduced |
| Sofinnova Investments, Inc. | 170,943 | $1.25M | 0.08% | +53,040+45.0% | Added |
| Royal Bank of Canada | 170,498 | $1.25M | 0.00% | +143,663+535.4% | Added |
| Privium Fund Management B.V. | 170,000 | $1.24M | 0.22% | +34,450+25.4% | Added |
| Rhumbline Advisers | 159,173 | $1.17M | 0.00% | −3,426−2.1% | Reduced |
| TD Asset Management Inc | 142,408 | $1.04M | 0.00% | −37,200−20.7% | Reduced |
| Invesco Ltd. | 141,126 | $1.03M | 0.00% | +26,167+22.8% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 134,276 | $982.9K | 0.00% | −11,032−7.6% | Reduced |
| Man Group plc | 132,771 | $971.9K | 0.00% | +73,492+124.0% | Added |
| Qube Research & Technologies Ltd | 127,983 | $936.8K | 0.00% | −463,401−78.4% | Reduced |
| Manufacturers Life Insurance Company, The | 125,359 | $917.6K | 0.00% | −38,340−23.4% | Reduced |
| Boothbay Fund Management, LLC | 121,162 | $886.9K | 0.02% | −11,729−8.8% | Reduced |
| ADAR1 Capital Management, LLC | 119,067 | $871.6K | 0.09% | +4,253+3.7% | Added |
| Cinctive Capital Management LP | 110,537 | $809.1K | 0.04% | −167,227−60.2% | Reduced |
| Ameriprise Financial Inc | 107,865 | $789.6K | 0.00% | +107,865 | New |
| New York State Common Retirement Fund | 107,046 | $783.6K | 0.00% | −43,467−28.9% | Reduced |
| James J. Burns & Company, LLC | 105,802 | $774.5K | 0.12% | −16,111−13.2% | Reduced |
| Legal & General Group Plc | 101,916 | $746.0K | 0.00% | −134−0.1% | Reduced |
| California State Teachers Retirement System | 98,495 | $721.0K | 0.00% | +258+0.3% | Added |
| Ikarian Capital, LLC | 95,955 | $702.4K | 0.16% | −65,182−40.5% | Reduced |
| Deutsche Bank AG | 94,265 | $690.0K | 0.00% | +9,734+11.5% | Added |
| ExodusPoint Capital Management, LP | 94,080 | $688.7K | 0.01% | +83,816+816.6% | Added |
| Alliancebernstein L.P. | 92,830 | $679.5K | 0.00% | 00.0% | Unchanged |
| Knott David M Jr | 90,000 | $658.8K | 0.28% | +50,000+125.0% | Added |
| Macquarie Group Ltd | 81,955 | $600.0K | 0.00% | −184,901−69.3% | Reduced |
| China Universal Asset Management Co., Ltd. | 77,895 | $570.2K | 0.05% | −15,475−16.6% | Reduced |
| a16z Perennial Management, L.P. | 77,619 | $568.2K | 0.05% | 00.0% | Unchanged |
| Wells Fargo & Company | 73,811 | $540.3K | 0.00% | −50,856−40.8% | Reduced |
| SEI Investments Co | 72,255 | $528.9K | 0.00% | −16,564−18.6% | Reduced |
| Twinbeech Capital LP | 65,091 | $476.5K | 0.02% | −98,654−60.2% | Reduced |
| Franklin Resources Inc | 62,259 | $455.7K | 0.00% | +277+0.4% | Added |
| HighVista Strategies LLC | 59,261 | $433.8K | 0.11% | +23,303+64.8% | Added |
| MetLife Investment Management | 59,206 | $433.4K | 0.00% | −8,051−12.0% | Reduced |
| State of Wisconsin Investment Board | 59,131 | $432.8K | 0.00% | +13,673+30.1% | Added |
| SummitTX Capital, L.P. | 53,611 | $392.4K | 0.02% | +53,611 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 52,046 | $381.0K | 0.00% | −257−0.5% | Reduced |
| Janus Henderson Group PLC | 51,700 | $378.7K | 0.00% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 51,198 | $375.0K | 0.03% | +51,198 | New |
| Handelsbanken Fonder AB | 50,800 | $372.0K | 0.00% | 00.0% | Unchanged |
| Sphera Funds Management Ltd. | 50,000 | $366.0K | 0.09% | +50,000 | New |
| Intech Investment Management LLC | 45,888 | $335.9K | 0.00% | −20,306−30.7% | Reduced |