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Wave Life Sciences, Inc.

WVE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001631574

In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q1 2025

Institutional positions in Wave Life Sciences, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
197
+14 vs. Q4 2024
Shares held
131.4M
+3.33M (+2.6%) vs. Q4 2024
Total value
$1.06B
−$522.2M (−33.0%) vs. Q4 2024
New holders
34
83 more added
Sold out
20
51 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 197 institutions
Q1 2021: 102 institutionsQ2 2021: 87 institutionsQ3 2021: 88 institutionsQ4 2021: 90 institutionsQ1 2022: 82 institutionsQ2 2022: 60 institutionsQ3 2022: 61 institutionsQ4 2022: 75 institutionsQ1 2023: 73 institutionsQ2 2023: 81 institutionsQ3 2023: 85 institutionsQ4 2023: 115 institutionsQ1 2024: 132 institutionsQ2 2024: 144 institutionsQ3 2024: 162 institutionsQ4 2024: 184 institutionsQ1 2025: 197 institutionsQ2 2025: 177 institutionsQ3 2025: 189 institutionsQ4 2025: 219 institutionsQ1 2026: 232 institutionsQ2 2026: 239 institutions
Value heldQ1 2025: $1.06B
Q1 2021: $214.8MQ2 2021: $246.7MQ3 2021: $183.5MQ4 2021: $148.5MQ1 2022: $95.4MQ2 2022: $220.3MQ3 2022: $242.8MQ4 2022: $476.9MQ1 2023: $303.5MQ2 2023: $262.7MQ3 2023: $417.4MQ4 2023: $468.0MQ1 2024: $572.3MQ2 2024: $474.4MQ3 2024: $986.1MQ4 2024: $1.59BQ1 2025: $1.06BQ2 2025: $903.1MQ3 2025: $1.05BQ4 2025: $3.11BQ1 2026: $1.25BQ2 2026: $1.06B
Institutions holding WVE and their total value by quarter
QuarterHoldersValue
Q2 2026239$1.06B
Q1 2026232$1.25B
Q4 2025219$3.11B
Q3 2025189$1.05B
Q2 2025177$903.1M
Q1 2025197$1.06B
Q4 2024184$1.59B
Q3 2024162$986.1M
Q2 2024144$474.4M
Q1 2024132$572.3M
Q4 2023115$468.0M
Q3 202385$417.4M
Q2 202381$262.7M
Q1 202373$303.5M
Q4 202275$476.9M
Q3 202261$242.8M
Q2 202260$220.3M
Q1 202282$95.4M
Q4 202190$148.5M
Q3 202188$183.5M
Q2 202187$246.7M
Q1 2021102$214.8M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q4 2024.

Institutions holding WVE in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.18,202,009$147.1M2.46%00.0%Unchanged
Adage Capital Partners GP, L.L.C.12,516,500$101.1M0.19%+2,894,396+30.1%Added
BlackRock, Inc.9,628,612$77.8M0.00%+268,449+2.9%Added
Maverick Capital LtdSuperinvestorMaverick Capital8,261,683$66.8M1.20%+4410.0%Added
Driehaus Capital Management LLC6,358,599$51.4M0.50%−353,850−5.3%Reduced
M28 Capital Management LP5,664,548$45.8M62.72%00.0%Unchanged
Kynam Capital Management, LP4,899,497$39.6M3.39%00.0%Unchanged
Price T Rowe Associates Inc4,125,291$33.3M0.00%−973,575−19.1%Reduced
Bellevue Group AG4,094,458$33.1M0.74%00.0%Unchanged
683 Capital Management, LLC3,925,000$31.7M3.22%+140,000+3.7%Added
Siren, L.L.C.3,696,322$29.9M1.68%−54,169−1.4%Reduced
Vanguard Group Inc3,206,403$25.9M0.00%+23,891+0.8%Added
Emerald Advisers, LLC3,133,558$25.3M1.14%−28,811−0.9%Reduced
Geode Capital Management, LLC2,592,399$21.0M0.00%+121,648+4.9%Added
Primecap Management Co2,507,520$20.3M0.02%−12,000−0.5%Reduced
Loomis Sayles & Co L P2,436,540$19.7M0.03%+775,674+46.7%Added
State Street Corp2,417,963$19.5M0.00%−8,634−0.4%Reduced
Artisan Partners Limited Partnership2,370,153$19.2M0.03%+463,363+24.3%Added
FMR LLC2,144,827$17.3M0.00%+317,107+17.3%Added
Emerald Mutual Fund Advisers Trust1,930,820$15.6M1.11%−2140.0%Reduced
Pfizer Inc1,875,000$15.2M3.02%00.0%Unchanged
Affinity Asset Advisors, LLC1,825,000$14.7M2.31%+325,000+21.7%Added
MPM Oncology Impact Management LP1,509,580$12.2M2.10%+20,343+1.4%Added
Morgan Stanley1,179,927$9.53M0.00%+121,541+11.5%Added
JPMorgan Chase & Co1,178,937$9.53M0.00%+474,600+67.4%Added
Silverarc Capital Management, LLC1,050,374$8.49M1.77%+441,477+72.5%Added
Polar Capital Holdings Plc1,003,500$8.11M0.05%+3,500+0.4%Added
Northern Trust Corp971,746$7.85M0.00%+9,995+1.0%Added
Charles Schwab Investment Management Inc963,125$7.78M0.00%+48,656+5.3%Added
RTW Investments, LP900,000$7.27M0.11%00.0%Unchanged
Voloridge Investment Management, LLC770,707$6.23M0.02%−75,123−8.9%Reduced
Goldman Sachs Group Inc557,644$4.51M0.00%+20,624+3.8%Added
Bank of America Corp535,265$4.32M0.00%+99,369+22.8%Added
Schroder Investment Management Group479,269$4.13M0.00%+479,269New
Woodline Partners LP452,060$3.65M0.02%+247+0.1%Added
Moody Aldrich Partners LLC439,827$3.55M0.74%+41,352+10.4%Added
Newtyn Management, LLC400,000$3.23M0.51%−25,000−5.9%Reduced
Twinbeech Capital LP396,048$3.20M0.06%+396,048New
Walleye Capital LLC390,840$3.16M0.03%−135,858−25.8%Reduced
Qube Research & Technologies Ltd374,864$3.03M0.00%+344,567+1,137.3%Added
Universal- Beteiligungs- und Servicegesellschaft mbH362,558$2.93M0.01%+267+0.1%Added
Baker Bros. Advisors LP344,063$2.78M0.03%00.0%Unchanged
Platinum Investment Management Ltd311,992$2.52M0.15%00.0%Unchanged
Principal Financial Group Inc308,044$2.49M0.00%+59,399+23.9%Added
Wellington Management Group LLP299,669$2.42M0.00%−11,634−3.7%Reduced
Macquarie Group Ltd272,326$2.20M0.00%+38,645+16.5%Added
Barclays PLC261,214$2.11M0.00%+65,661+33.6%Added
Bank of New York Mellon Corp247,251$2.00M0.00%+2,278+0.9%Added
Two Sigma Investments, LP241,714$1.95M0.00%−149,906−38.3%Reduced
F/M Investments LLC240,418$1.94M0.08%+14,384+6.4%Added
BNP Paribas Arbitrage, SA233,653$1.89M0.00%+90,811+63.6%Added
Trexquant Investment LP223,412$1.81M0.02%−215,940−49.1%Reduced
Wells Fargo & Company222,962$1.80M0.00%+173,106+347.2%Added
EAM Investors, LLC213,848$1.73M0.30%−869−0.4%Reduced
Renaissance Technologies LLC210,220$1.70M0.00%+168,700+406.3%Added
Dark Forest Capital Management LP197,216$1.59M0.07%+173,065+716.6%Added
Swiss National Bank192,000$1.55M0.00%−16,800−8.0%Reduced
UBS Asset Management Americas Inc183,402$1.48M0.00%+18,164+11.0%Added
UBS Group AG168,289$1.36M0.00%+46,174+37.8%Added
Manufacturers Life Insurance Company, The155,786$1.26M0.00%−51,901−25.0%Reduced
Verition Fund Management LLC154,757$1.25M0.01%+72,874+89.0%Added
TD Asset Management Inc154,408$1.25M0.00%−161,798−51.2%Reduced
New York State Common Retirement Fund150,513$1.22M0.00%+41,429+38.0%Added
Rhumbline Advisers132,700$1.07M0.00%+7,860+6.3%Added
Connor, Clark & Lunn Investment Management Ltd.126,046$1.02M0.00%−261,825−67.5%Reduced
James J. Burns & Company, LLC121,913$985.1K0.18%+10,802+9.7%Added
Susquehanna International Group, LLP117,089$946.1K0.00%+76,558+188.9%Added
Legal & General Group Plc116,012$937.8K0.00%−2,642−2.2%Reduced
Engineers Gate Manager LP115,668$934.6K0.02%+73,289+172.9%Added
Privium Fund Management B.V.113,550$917.5K0.24%+25,550+29.0%Added
Prelude Capital Management, LLC109,330$883.4K0.09%+109,330New
D. E. Shaw & Co., Inc.106,554$861.0K0.00%−609,699−85.1%Reduced
State of Wisconsin Investment Board105,902$855.7K0.00%+25,075+31.0%Added
Hussman Strategic Advisors, Inc.105,000$848.4K0.21%+63,000+150.0%Added
Norges Bank100,000$808.0K0.00%00.0%Unchanged
Atom Investors LP98,798$798.3K0.10%+21,473+27.8%Added
California State Teachers Retirement System98,237$793.8K0.00%00.0%Unchanged
ExodusPoint Capital Management, LP96,268$778.0K0.01%+96,268New
Alliancebernstein L.P.93,565$756.0K0.00%+2,975+3.3%Added
Susquehanna Fundamental Investments, LLC93,223$753.2K0.01%+93,223New
SEI Investments Co92,611$748.3K0.00%+15,001+19.3%Added
Citigroup Inc91,161$736.6K0.00%−2,968−3.2%Reduced
StemPoint Capital LP89,833$725.9K0.23%−631,376−87.5%Reduced
Invesco Ltd.78,880$637.4K0.00%+38,870+97.2%Added
a16z Perennial Management, L.P.77,619$627.2K0.08%00.0%Unchanged
Tudor Investment Corp Et Al76,926$621.6K0.01%+76,926New
Intech Investment Management LLC76,693$619.7K0.01%+29,547+62.7%Added
Voya Investment Management LLC75,369$609.0K0.00%−1,791−2.3%Reduced
Aquatic Capital Management LLC71,741$579.7K0.01%−10,277−12.5%Reduced
Deutsche Bank AG70,910$573.0K0.00%+444+0.6%Added
Citadel Advisors LLC61,956$500.6K0.00%+58,738+1,825.3%Added
Mirae Asset Global ETFs Holdings Ltd.57,349$463.4K0.00%+4,957+9.5%Added
PDT Partners, LLC55,918$451.8K0.03%−13,302−19.2%Reduced
Federated Hermes, Inc.55,858$451.3K0.00%−12,162−17.9%Reduced
MetLife Investment Management55,403$447.7K0.00%−538−1.0%Reduced
Janus Henderson Group PLC51,700$445.7K0.00%00.0%Unchanged
Glenmede Trust Co NA53,792$434.6K0.00%+6,383+13.5%Added
HighVista Strategies LLC53,374$431.3K0.17%+53,374New
Nuveen, LLC50,203$431.0K0.00%+50,203New
China Universal Asset Management Co., Ltd.52,520$424.4K0.04%−1,747−3.2%Reduced