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Wave Life Sciences, Inc.

WVE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001631574

In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q1 2026

Institutional positions in Wave Life Sciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
232
+16 vs. Q4 2025
Shares held
172.6M
−6.53M (−3.6%) vs. Q4 2025
Total value
$1.25B
−$1.80B (−59.0%) vs. Q4 2025
New holders
51
107 more added
Sold out
35
48 more reduced

3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 232 institutions
Q1 2021: 102 institutionsQ2 2021: 87 institutionsQ3 2021: 88 institutionsQ4 2021: 90 institutionsQ1 2022: 82 institutionsQ2 2022: 60 institutionsQ3 2022: 61 institutionsQ4 2022: 75 institutionsQ1 2023: 73 institutionsQ2 2023: 81 institutionsQ3 2023: 85 institutionsQ4 2023: 115 institutionsQ1 2024: 132 institutionsQ2 2024: 144 institutionsQ3 2024: 162 institutionsQ4 2024: 184 institutionsQ1 2025: 197 institutionsQ2 2025: 177 institutionsQ3 2025: 189 institutionsQ4 2025: 219 institutionsQ1 2026: 232 institutionsQ2 2026: 239 institutions
Value heldQ1 2026: $1.25B
Q1 2021: $214.8MQ2 2021: $246.7MQ3 2021: $183.5MQ4 2021: $148.5MQ1 2022: $95.4MQ2 2022: $220.3MQ3 2022: $242.8MQ4 2022: $476.9MQ1 2023: $303.5MQ2 2023: $262.7MQ3 2023: $417.4MQ4 2023: $468.0MQ1 2024: $572.3MQ2 2024: $474.4MQ3 2024: $986.1MQ4 2024: $1.59BQ1 2025: $1.06BQ2 2025: $903.1MQ3 2025: $1.05BQ4 2025: $3.11BQ1 2026: $1.25BQ2 2026: $1.06B
Institutions holding WVE and their total value by quarter
QuarterHoldersValue
Q2 2026239$1.06B
Q1 2026232$1.25B
Q4 2025219$3.11B
Q3 2025189$1.05B
Q2 2025177$903.1M
Q1 2025197$1.06B
Q4 2024184$1.59B
Q3 2024162$986.1M
Q2 2024144$474.4M
Q1 2024132$572.3M
Q4 2023115$468.0M
Q3 202385$417.4M
Q2 202381$262.7M
Q1 202373$303.5M
Q4 202275$476.9M
Q3 202261$242.8M
Q2 202260$220.3M
Q1 202282$95.4M
Q4 202190$148.5M
Q3 202188$183.5M
Q2 202187$246.7M
Q1 2021102$214.8M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q4 2025.

Institutions holding WVE in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.26,975,505$195.6M2.07%+8,772,496+48.2%Added
GSK plc18,245,691$132.3M22.08%00.0%Unchanged
BlackRock, Inc.14,117,412$102.4M0.00%+1,468,505+11.6%Added
Maverick Capital LtdSuperinvestorMaverick Capital10,161,399$73.7M0.86%+881,162+9.5%Added
Price T Rowe Associates Inc8,704,550$63.1M0.01%+1,297,178+17.5%Added
Driehaus Capital Management LLC5,431,021$39.4M0.29%−1,150,046−17.5%Reduced
Federated Hermes, Inc.5,317,457$38.6M0.06%+572,937+12.1%Added
FMR LLC5,192,761$37.6M0.00%−9,943,222−65.7%Reduced
683 Capital Management, LLC4,900,000$35.5M3.30%+885,000+22.0%Added
Primecap Management Co4,832,952$35.0M0.03%+737,670+18.0%Added
M28 Capital Management LP4,588,284$33.3M61.83%−1,076,264−19.0%Reduced
State Street Corp3,674,033$26.6M0.00%+677,949+22.6%Added
Geode Capital Management, LLC3,579,099$26.0M0.00%+408,989+12.9%Added
Siren, L.L.C.2,450,000$17.8M0.49%00.0%Unchanged
Citadel Advisors LLC2,202,856$16.0M0.01%+1,412,892+178.9%Added
Two Sigma Investments, LP1,878,115$13.6M0.01%+1,128,667+150.6%Added
First Light Asset Management, LLC1,843,968$13.4M1.20%−9,883−0.5%Reduced
Marshall Wace, LLP1,789,882$13.0M0.01%+1,789,882New
Pfizer Inc1,875,000$11.9M5.00%00.0%Unchanged
Vanguard Capital Management LLC1,611,853$11.7M0.00%+1,611,853New
Squarepoint Ops LLC1,462,390$10.6M0.02%+578,804+65.5%Added
Affinity Asset Advisors, LLC1,401,727$10.2M0.60%−1,298,273−48.1%Reduced
Goldman Sachs Group Inc1,383,590$10.0M0.00%−1,470,492−51.5%Reduced
Morgan Stanley1,361,001$9.87M0.00%+951,338+232.2%Added
RTW Investments, LP1,350,000$9.79M0.10%00.0%Unchanged
Schroder Investment Management Group1,441,059$9.54M0.01%+435,075+43.2%Added
Algert Global LLC1,315,589$9.54M0.14%+1,193,119+974.2%Added
Emerald Advisers, LLC1,261,183$9.14M0.29%−1,193,906−48.6%Reduced
Northern Trust Corp1,189,230$8.62M0.00%+156,162+15.1%Added
Charles Schwab Investment Management Inc1,179,279$8.55M0.00%−12,082−1.0%Reduced
Vanguard Portfolio Management LLC1,176,207$8.53M0.00%+1,176,207New
Pictet Asset Management Holding SA1,149,127$8.20M0.01%+343,226+42.6%Added
Trexquant Investment LP1,089,642$7.90M0.06%+698,531+178.6%Added
Adage Capital Partners GP, L.L.C.1,000,000$7.25M0.01%−8,786,061−89.8%Reduced
Millennium Management LLC972,241$7.05M0.01%+387,608+66.3%Added
Kynam Capital Management, LP965,193$7.00M0.44%−1,203,912−55.5%Reduced
Vanguard Fiduciary Trust Co878,833$6.37M0.00%+878,833New
Baker Bros. Advisors LP822,638$5.96M0.03%+478,575+139.1%Added
Emerald Mutual Fund Advisers Trust814,529$5.91M0.29%−600,136−42.4%Reduced
SymBiosis Capital Partners, LLC750,000$5.44M10.30%+750,000New
Nuveen, LLC657,720$4.77M0.00%+324,985+97.7%Added
Connor, Clark & Lunn Investment Management Ltd.624,735$4.53M0.01%+555,657+804.4%Added
JPMorgan Chase & Co670,170$4.44M0.00%−222,716−24.9%Reduced
Tang Capital Management LLC600,000$4.35M0.22%00.0%Unchanged
Renaissance Technologies LLC597,220$4.33M0.01%+360,800+152.6%Added
Standard Life Aberdeen plc550,000$3.99M0.01%+550,000New
Sphera Funds Management Ltd.548,272$3.97M0.68%+140,106+34.3%Added
UBS Group AG538,997$3.91M0.00%+270,274+100.6%Added
Kennedy Capital Management, Inc.519,768$3.77M0.08%+27,331+5.6%Added
Citigroup Inc501,477$3.64M0.00%+454,718+972.5%Added
Walleye Capital LLC493,512$3.58M0.02%+114,689+30.3%Added
AQR Capital Management LLC451,185$3.27M0.00%+248,464+122.6%Added
Universal- Beteiligungs- und Servicegesellschaft mbH415,458$3.01M0.01%+3,964+1.0%Added
Wellington Management Group LLP373,794$2.71M0.00%+8,559+2.3%Added
Bank of New York Mellon Corp361,204$2.62M0.00%+39,759+12.4%Added
Jump Financial, LLC360,054$2.61M0.04%+46,545+14.8%Added
Woodline Partners LP350,531$2.54M0.01%00.0%Unchanged
TD Asset Management Inc338,826$2.46M0.00%+86,666+34.4%Added
Aquatic Capital Management LLC323,573$2.35M0.07%+323,573New
HRT Financial LP321,376$2.33M0.01%+21,658+7.2%Added
Newtyn Management, LLC300,000$2.17M0.23%00.0%Unchanged
Alliancebernstein L.P.125,096$2.13M0.00%+13,066+11.7%Added
Voloridge Investment Management, LLC288,502$2.09M0.01%−433,735−60.1%Reduced
Gsa Capital Partners LLP282,719$2.05M0.13%+282,719New
BNP Paribas Arbitrage, SA281,023$2.04M0.00%+199,001+242.6%Added
Platinum Investment Management Ltd275,269$2.00M0.50%+44,582+19.3%Added
Moody Aldrich Partners LLC272,533$1.98M0.36%−1,892−0.7%Reduced
Susquehanna International Group, LLP259,825$1.88M0.00%−119,162−31.4%Reduced
Privium Fund Management B.V.241,010$1.75M0.36%+48,000+24.9%Added
Manufacturers Life Insurance Company, The240,983$1.75M0.00%+58,255+31.9%Added
Bank of America Corp236,760$1.72M0.00%+53,905+29.5%Added
UBS Asset Management Americas Inc225,114$1.63M0.00%+60,129+36.4%Added
Swiss National Bank219,700$1.59M0.00%00.0%Unchanged
Balyasny Asset Management LLC211,074$1.53M0.00%+211,074New
Scientech Research LLC200,331$1.45M1.21%+184,758+1,186.4%Added
Invesco Ltd.199,740$1.45M0.00%+19,808+11.0%Added
Susquehanna Portfolio Strategies, LLC195,840$1.42M0.02%−34,672−15.0%Reduced
Barclays PLC189,865$1.38M0.00%−86,916−31.4%Reduced
Sofinnova Investments, Inc.189,253$1.37M0.07%+31,071+19.6%Added
Capital Fund Management S.A.183,331$1.33M0.01%+183,331New
Caitong International Asset Management Co., Ltd180,980$1.31M0.24%+170,623+1,647.4%Added
Elmind Capital, LP177,846$1.29M0.37%−270,000−60.3%Reduced
Duquesne Family Office LLCSuperinvestorDuquesne Family Office173,000$1.25M0.04%00.0%Unchanged
Rhumbline Advisers167,528$1.21M0.00%+25,633+18.1%Added
F/M Investments LLC164,921$1.20M0.08%−230,973−58.3%Reduced
Boothbay Fund Management, LLC160,311$1.16M0.03%−74,488−31.7%Reduced
Y-Intercept (Hong Kong) Ltd157,013$1.14M0.02%+157,013New
Qube Research & Technologies Ltd155,924$1.13M0.00%+155,924New
Mirae Asset Global ETFs Holdings Ltd.150,368$1.09M0.00%+15,810+11.7%Added
Burkehill Global Management, LP150,000$1.09M0.05%00.0%Unchanged
Twinbeech Capital LP145,825$1.06M0.11%+145,825New
California State Teachers Retirement System145,206$1.05M0.00%+37,526+34.8%Added
Advisory Services Network, LLC144,950$1.05M0.01%+124,050+593.5%Added
Capstone Capital Management Ltd144,029$1.04M1.05%+144,029New
Fred Alger Management, LLC139,218$1.01M0.00%+139,218New
Wells Fargo & Company136,173$987.3K0.00%−64,717−32.2%Reduced
James J. Burns & Company, LLC114,800$832.3K0.11%+8,998+8.5%Added
Deutsche Bank AG114,110$827.3K0.00%+18,404+19.2%Added
XTX Topco Ltd109,862$796.5K0.01%+109,862New
State of Wisconsin Investment Board108,164$784.2K0.00%+21,023+24.1%Added