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Wave Life Sciences, Inc.

WVE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001631574

In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q1 2026

Institutional positions in Wave Life Sciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
232
+16 vs. Q4 2025
Shares held
172.6M
−6.53M (−3.6%) vs. Q4 2025
Total value
$1.25B
−$1.80B (−59.0%) vs. Q4 2025
New holders
51
107 more added
Sold out
35
48 more reduced

3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 232 institutions
Q1 2021: 102 institutionsQ2 2021: 87 institutionsQ3 2021: 88 institutionsQ4 2021: 90 institutionsQ1 2022: 82 institutionsQ2 2022: 60 institutionsQ3 2022: 61 institutionsQ4 2022: 75 institutionsQ1 2023: 73 institutionsQ2 2023: 81 institutionsQ3 2023: 85 institutionsQ4 2023: 115 institutionsQ1 2024: 132 institutionsQ2 2024: 144 institutionsQ3 2024: 162 institutionsQ4 2024: 184 institutionsQ1 2025: 197 institutionsQ2 2025: 177 institutionsQ3 2025: 189 institutionsQ4 2025: 219 institutionsQ1 2026: 232 institutionsQ2 2026: 239 institutions
Value heldQ1 2026: $1.25B
Q1 2021: $214.8MQ2 2021: $246.7MQ3 2021: $183.5MQ4 2021: $148.5MQ1 2022: $95.4MQ2 2022: $220.3MQ3 2022: $242.8MQ4 2022: $476.9MQ1 2023: $303.5MQ2 2023: $262.7MQ3 2023: $417.4MQ4 2023: $468.0MQ1 2024: $572.3MQ2 2024: $474.4MQ3 2024: $986.1MQ4 2024: $1.59BQ1 2025: $1.06BQ2 2025: $903.1MQ3 2025: $1.05BQ4 2025: $3.11BQ1 2026: $1.25BQ2 2026: $1.06B
Institutions holding WVE and their total value by quarter
QuarterHoldersValue
Q2 2026239$1.06B
Q1 2026232$1.25B
Q4 2025219$3.11B
Q3 2025189$1.05B
Q2 2025177$903.1M
Q1 2025197$1.06B
Q4 2024184$1.59B
Q3 2024162$986.1M
Q2 2024144$474.4M
Q1 2024132$572.3M
Q4 2023115$468.0M
Q3 202385$417.4M
Q2 202381$262.7M
Q1 202373$303.5M
Q4 202275$476.9M
Q3 202261$242.8M
Q2 202260$220.3M
Q1 202282$95.4M
Q4 202190$148.5M
Q3 202188$183.5M
Q2 202187$246.7M
Q1 2021102$214.8M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q4 2025.

Institutions holding WVE in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Tudor Investment Corp Et Al97,900$709.8K0.00%+97,900New
Simplex Trading, LLC89,263$647.2K0.02%+68,137+322.5%Added
Quadrature Capital Ltd86,677$628.4K0.01%+86,677New
Ikarian Capital, LLC85,285$618.3K0.09%00.0%Unchanged
Nomura Asset Management International Inc.81,955$594.0K0.00%−121,789−59.8%Reduced
Engineers Gate Manager LP80,217$581.6K0.01%+80,217New
SEI Investments Co80,161$581.2K0.00%+25,704+47.2%Added
Legal & General Group Plc79,054$572.7K0.00%−14,931−15.9%Reduced
a16z Perennial Management, L.P.77,619$562.7K0.05%00.0%Unchanged
Virtu Financial LLC76,779$557.0K0.02%+49,890+185.5%Added
MetLife Investment Management76,265$552.9K0.00%+11,502+17.8%Added
Vanguard Asset Management, Ltd74,695$541.5K0.00%+74,695New
D. E. Shaw & Co., Inc.72,305$524.2K0.00%−193,827−72.8%Reduced
Voya Investment Management LLC69,092$500.9K0.00%−43,783−38.8%Reduced
Handelsbanken Fonder AB65,500$475.0K0.00%+10,800+19.7%Added
Winton Group Ltd65,045$471.6K0.02%+50,345+342.5%Added
Man Group plc64,036$464.3K0.00%+32,618+103.8%Added
Russell Investments Group, Ltd.58,052$420.9K0.00%+8,149+16.3%Added
Vanguard Global Advisers, LLC56,601$410.4K0.00%+56,601New
J. Goldman & Co LP53,896$390.7K0.02%+134+0.2%Added
Verition Fund Management LLC53,895$390.7K0.00%+53,895New
Zurcher Kantonalbank (Zurich Cantonalbank)51,955$376.7K0.00%−10,774−17.2%Reduced
Janus Henderson Group PLC51,700$374.6K0.00%00.0%Unchanged
Quantinno Capital Management LP47,885$347.2K0.00%+8,960+23.0%Added
Matisse Capital46,723$338.7K0.14%+4,530+10.7%Added
ADAR1 Capital Management, LLC44,900$325.5K0.02%+44,900New
Glenmede Trust Co NA44,241$320.7K0.00%+1,509+3.5%Added
Caption Management, LLC43,200$313.2K0.01%+43,200New
Ameriprise Financial Inc40,374$292.7K0.00%−358,042−89.9%Reduced
Knott David M Jr40,000$290.0K0.17%−50,000−55.6%Reduced
Raymond James Financial Inc39,625$287.3K0.00%−71,545−64.4%Reduced
Intech Investment Management LLC39,437$285.9K0.00%+8,770+28.6%Added
Envestnet Asset Management Inc38,546$279.5K0.00%−1,274−3.2%Reduced
Police & Firemen's Retirement System of New Jersey38,172$276.7K0.00%+7,139+23.0%Added
State of New Jersey Common Pension Fund D38,071$276.0K0.00%+49+0.1%Added
New York State Common Retirement Fund35,920$260.4K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.33,407$242.2K0.02%−6,335−15.9%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.33,023$239.4K0.00%−816−2.4%Reduced
Exchange Traded Concepts, LLC32,778$237.6K0.00%+7,163+28.0%Added
Arizona State Retirement System30,598$221.8K0.00%−47−0.2%Reduced
HighTower Advisors, LLC29,232$211.9K0.00%+6,402+28.0%Added
AlphaCentric Advisors LLC29,175$211.5K0.21%+1,585+5.7%Added
ProShare Advisors LLC28,678$207.9K0.00%+142+0.5%Added
Entropy Technologies, LP28,348$205.5K0.01%−2,265−7.4%Reduced
Vanguard Investments Australia, Ltd.27,701$200.8K0.00%+27,701New
Advisor Group Holdings, Inc.27,666$200.6K0.00%+26,491+2,254.6%Added
Creative Planning27,574$199.9K0.00%+9,453+52.2%Added
Victory Capital Management Inc24,793$179.7K0.00%+9,072+57.7%Added
KLP Kapitalforvaltning AS24,000$174.0K0.00%00.0%Unchanged
Brinker Capital Investments, LLC22,846$165.6K0.00%−2,184−8.7%Reduced
Ieq Capital, LLC22,532$163.4K0.00%+22,532New
Private Advisor Group, LLC22,100$160.2K0.00%+22,100New
AlphaGrep UK Ltd21,614$156.7K0.05%+21,614New
Prudential Financial Inc21,090$152.9K0.00%+21,090New
SG Americas Securities, LLC20,923$152.0K0.00%−46,108−68.8%Reduced
Mariner, LLC20,891$151.3K0.00%+20,891New
Profund Advisors LLC18,953$137.4K0.01%+4,368+29.9%Added
Gabelli Funds LLC17,500$126.9K0.00%+17,500New
Chicago Partners Investment Group LLC16,783$123.9K0.00%+16,783New
State Board of Administration of Florida Retirement System16,950$122.9K0.00%00.0%Unchanged
Royal Bank of Canada16,702$122.0K0.00%−6,504−28.0%Reduced
Canada Pension Plan Investment Board16,800$121.8K0.00%+16,800New
Virtus Investment Advisers, Inc.16,465$119.4K0.03%+401+2.5%Added
Walleye Trading LLC16,288$118.1K0.00%−16,953−51.0%Reduced
Savant Capital, LLC15,951$115.6K0.00%+3,000+23.2%Added
Axq Capital, LP15,745$114.2K0.01%+15,745New
Pavaki Capital Management LLC15,000$108.8K0.08%+15,000New
CWM, LLC14,851$107.7K0.00%+12,734+601.5%Added
Teacher Retirement System of Texas14,422$104.6K0.00%−2,021−12.3%Reduced
Cresset Asset Management, LLC14,380$104.3K0.00%−3,549−19.8%Reduced
First Trust Advisors LP13,518$98.0K0.00%+1,830+15.7%Added
Mercer Global Advisors Inc12,626$91.5K0.00%+12,626New
Xponance, Inc.12,303$89.2K0.00%+12,303New
Bridgefront Capital, LLC12,146$88.1K0.02%+12,146New
Ameritas Investment Partners, Inc.11,436$82.9K0.00%+2,072+22.1%Added
Insigneo Advisory Services, LLC11,000$79.8K0.01%+11,000New
Rafferty Asset Management, LLC10,420$75.5K0.00%−1,137−9.8%Reduced
LPL Financial LLC10,373$75.2K0.00%+10,373New
Inceptionr LLC10,132$73.5K0.02%−504−4.7%Reduced
Bessemer Group Inc9,925$72.0K0.00%−37−0.4%Reduced
Mirae Asset Global Investments Co., Ltd.9,819$71.2K0.00%+1,695+20.9%Added
Tower Research Capital LLC (TRC)9,740$70.6K0.00%+211+2.2%Added
Acadian Asset Management LLC9,755$70.0K0.00%+3,932+67.5%Added
US Bancorp7,025$50.9K0.00%+762+12.2%Added
Group One Trading, L.P.6,260$45.4K0.00%−61,709−90.8%Reduced
Hudson Bay Capital Management LP6,200$45.0K0.00%+6,200New
Bellevue Group AG5,261$38.1K0.00%−1,485,257−99.6%Reduced
GF Fund Management Co. Ltd.3,754$27.2K0.00%+469+14.3%Added
KBC Group NV3,297$24.0K0.00%+3,297New
Ancora Advisors, LLC3,000$21.8K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC2,970$21.5K0.00%+2,570+642.5%Added
Capital Advisors, Ltd. LLC2,500$18.0K0.00%+2,500New
Quadrant Capital Group LLC2,396$17.4K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.2,266$16.4K0.00%+1,405+163.2%Added
Larson Financial Group LLC2,083$15.1K0.00%+1,241+147.4%Added
Smartleaf Asset Management LLC2,252$14.9K0.00%+9+0.4%Added
Farther Finance Advisors, LLC1,972$13.5K0.00%+27+1.4%Added
Nisa Investment Advisors, LLC1,814$13.2K0.00%+506+38.7%Added
MAI Capital Management1,341$9.72K0.00%+1,330+12,090.9%Added
Sterling Capital Management LLC1,334$9.67K0.00%−90−6.3%Reduced