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Wave Life Sciences, Inc.

WVE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001631574

In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q4 2024

Institutional positions in Wave Life Sciences, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
184
+23 vs. Q3 2024
Shares held
128.6M
+8.38M (+7.0%) vs. Q3 2024
Total value
$1.59B
+$605.0M (+61.4%) vs. Q3 2024
New holders
47
76 more added
Sold out
24
38 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 184 institutions
Q1 2021: 102 institutionsQ2 2021: 87 institutionsQ3 2021: 88 institutionsQ4 2021: 90 institutionsQ1 2022: 82 institutionsQ2 2022: 60 institutionsQ3 2022: 61 institutionsQ4 2022: 75 institutionsQ1 2023: 73 institutionsQ2 2023: 81 institutionsQ3 2023: 85 institutionsQ4 2023: 115 institutionsQ1 2024: 132 institutionsQ2 2024: 144 institutionsQ3 2024: 162 institutionsQ4 2024: 184 institutionsQ1 2025: 197 institutionsQ2 2025: 177 institutionsQ3 2025: 189 institutionsQ4 2025: 219 institutionsQ1 2026: 232 institutionsQ2 2026: 239 institutions
Value heldQ4 2024: $1.59B
Q1 2021: $214.8MQ2 2021: $246.7MQ3 2021: $183.5MQ4 2021: $148.5MQ1 2022: $95.4MQ2 2022: $220.3MQ3 2022: $242.8MQ4 2022: $476.9MQ1 2023: $303.5MQ2 2023: $262.7MQ3 2023: $417.4MQ4 2023: $468.0MQ1 2024: $572.3MQ2 2024: $474.4MQ3 2024: $986.1MQ4 2024: $1.59BQ1 2025: $1.06BQ2 2025: $903.1MQ3 2025: $1.05BQ4 2025: $3.11BQ1 2026: $1.25BQ2 2026: $1.06B
Institutions holding WVE and their total value by quarter
QuarterHoldersValue
Q2 2026239$1.06B
Q1 2026232$1.25B
Q4 2025219$3.11B
Q3 2025189$1.05B
Q2 2025177$903.1M
Q1 2025197$1.06B
Q4 2024184$1.59B
Q3 2024162$986.1M
Q2 2024144$474.4M
Q1 2024132$572.3M
Q4 2023115$468.0M
Q3 202385$417.4M
Q2 202381$262.7M
Q1 202373$303.5M
Q4 202275$476.9M
Q3 202261$242.8M
Q2 202260$220.3M
Q1 202282$95.4M
Q4 202190$148.5M
Q3 202188$183.5M
Q2 202187$246.7M
Q1 2021102$214.8M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q3 2024.

Institutions holding WVE in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.18,202,009$225.2M3.00%00.0%Unchanged
Adage Capital Partners GP, L.L.C.9,622,104$119.0M0.21%−81,247−0.8%Reduced
BlackRock, Inc.9,360,163$115.8M0.00%+2,061,740+28.2%Added
Maverick Capital LtdSuperinvestorMaverick Capital8,261,242$102.2M1.84%−1,786,278−17.8%Reduced
Driehaus Capital Management LLC6,712,449$83.0M0.69%+853,589+14.6%Added
M28 Capital Management LP5,664,548$70.1M68.79%−500,000−8.1%Reduced
Price T Rowe Associates Inc5,098,866$63.1M0.01%+1,972,262+63.1%Added
Kynam Capital Management, LP4,899,497$60.6M4.00%00.0%Unchanged
Bellevue Group AG4,094,458$50.6M0.97%00.0%Unchanged
683 Capital Management, LLC3,785,000$46.8M4.61%−415,000−9.9%Reduced
Siren, L.L.C.3,750,491$46.4M2.05%−1,970,681−34.4%Reduced
Vanguard Group Inc3,182,512$39.4M0.00%+294,956+10.2%Added
Emerald Advisers, LLC3,162,369$39.1M1.52%+280,859+9.7%Added
Primecap Management Co2,519,520$31.2M0.02%−61,180−2.4%Reduced
Geode Capital Management, LLC2,470,751$30.6M0.00%+201,087+8.9%Added
State Street Corp2,426,597$30.0M0.00%+105,349+4.5%Added
Emerald Mutual Fund Advisers Trust1,931,034$23.9M1.45%−192,432−9.1%Reduced
Artisan Partners Limited Partnership1,906,790$23.6M0.04%−53,680−2.7%Reduced
Pfizer Inc1,875,000$23.2M0.89%+1,875,000New
FMR LLC1,827,720$22.6M0.00%+287,530+18.7%Added
Loomis Sayles & Co L P1,660,866$20.5M0.03%+1,660,866New
Affinity Asset Advisors, LLC1,500,000$18.6M2.90%+100,000+7.1%Added
MPM Oncology Impact Management LP1,489,237$18.4M2.62%+864,766+138.5%Added
Millennium Management LLC1,180,838$14.6M0.01%+329,173+38.7%Added
Morgan Stanley1,058,386$13.1M0.00%+414,051+64.3%Added
Polar Capital Holdings Plc1,000,000$12.4M0.07%+1,000,000New
Northern Trust Corp961,751$11.9M0.00%+162,386+20.3%Added
Charles Schwab Investment Management Inc914,469$11.3M0.00%+69,852+8.3%Added
RTW Investments, LP900,000$11.1M0.17%00.0%Unchanged
Voloridge Investment Management, LLC845,830$10.5M0.04%+845,830New
StemPoint Capital LP721,209$8.92M2.24%+421,209+140.4%Added
D. E. Shaw & Co., Inc.716,253$8.86M0.01%+297,792+71.2%Added
JPMorgan Chase & Co704,337$8.71M0.00%+328,670+87.5%Added
Silverarc Capital Management, LLC608,897$7.53M1.68%−18,655−3.0%Reduced
Polar Asset Management Partners Inc.557,323$6.89M0.10%+71,300+14.7%Added
Nuveen Asset Management, LLC553,439$6.85M0.00%+137,159+32.9%Added
Goldman Sachs Group Inc537,020$6.64M0.00%+162,657+43.4%Added
Walleye Capital LLC526,698$6.52M0.06%−75,743−12.6%Reduced
Woodline Partners LP451,813$5.59M0.04%00.0%Unchanged
Trexquant Investment LP439,352$5.43M0.06%+150,538+52.1%Added
Bank of America Corp435,896$5.39M0.00%+160,820+58.5%Added
Newtyn Management, LLC425,000$5.26M0.92%00.0%Unchanged
Moody Aldrich Partners LLC398,475$4.93M0.91%+95,413+31.5%Added
Two Sigma Investments, LP391,620$4.84M0.01%+265,437+210.4%Added
Connor, Clark & Lunn Investment Management Ltd.387,871$4.80M0.02%+62,862+19.3%Added
Universal- Beteiligungs- und Servicegesellschaft mbH362,291$4.48M0.01%+362,291New
Baker Bros. Advisors LP344,063$4.26M0.05%00.0%Unchanged
TD Asset Management Inc316,206$3.91M0.00%+64,400+25.6%Added
Platinum Investment Management Ltd311,992$3.86M0.23%−149,675−32.4%Reduced
Wellington Management Group LLP311,303$3.85M0.00%−4,199−1.3%Reduced
Principal Financial Group Inc248,645$3.08M0.00%+248,645New
Bank of New York Mellon Corp244,973$3.03M0.00%+43,143+21.4%Added
Macquarie Group Ltd233,681$2.89M0.00%+151,726+185.1%Added
F/M Investments LLC226,034$2.80M0.10%+226,034New
EAM Investors, LLC214,717$2.66M0.38%+214,717New
Swiss National Bank208,800$2.58M0.00%+52,300+33.4%Added
Manufacturers Life Insurance Company, The207,687$2.57M0.00%+39,546+23.5%Added
Barclays PLC195,553$2.42M0.00%+36,312+22.8%Added
Cinctive Capital Management LP191,963$2.37M0.13%−164,345−46.1%Reduced
Marshall Wace, LLP183,875$2.27M0.00%+55,325+43.0%Added
Maven Securities LTD170,000$2.10M0.34%−680,000−80.0%Reduced
UBS Asset Management Americas Inc165,238$2.04M0.00%+20,520+14.2%Added
Crestline Management, LP158,336$1.96M0.07%+23,076+17.1%Added
BNP Paribas Arbitrage, SA142,842$1.77M0.00%+101,014+241.5%Added
Rhumbline Advisers124,840$1.54M0.00%+17,316+16.1%Added
Jump Financial, LLC123,707$1.53M0.03%+123,707New
UBS Group AG122,115$1.51M0.00%+53,313+77.5%Added
Legal & General Group Plc118,654$1.47M0.00%+31,193+35.7%Added
James J. Burns & Company, LLC111,111$1.37M0.24%+11,000+11.0%Added
New York State Common Retirement Fund109,084$1.35M0.00%+6,900+6.8%Added
Norges Bank100,000$1.24M0.00%00.0%Unchanged
California State Teachers Retirement System98,237$1.22M0.00%+23,215+30.9%Added
Citigroup Inc94,129$1.16M0.00%+25,123+36.4%Added
Alliancebernstein L.P.90,590$1.12M0.00%+32,520+56.0%Added
Privium Fund Management B.V.88,000$1.09M0.25%+39,166+80.2%Added
Bamco Inc85,000$1.05M0.00%+85,000New
Aquatic Capital Management LLC82,018$1.01M0.03%+82,018New
Verition Fund Management LLC81,883$1.01M0.01%+81,883New
State of Wisconsin Investment Board80,827$999.8K0.00%+80,827New
a16z Perennial Management, L.P.77,619$960.1K0.11%00.0%Unchanged
SEI Investments Co77,610$960.0K0.00%+9,138+13.3%Added
Atom Investors LP77,325$956.5K0.12%+77,325New
Voya Investment Management LLC77,160$954.5K0.00%+51,281+198.2%Added
Deutsche Bank AG70,466$871.7K0.00%+25,756+57.6%Added
PDT Partners, LLC69,220$856.3K0.08%−5,747−7.7%Reduced
Quantbot Technologies LP68,927$852.6K0.03%+68,927New
Two Sigma Advisers, LP68,100$842.4K0.00%+68,100New
Federated Hermes, Inc.68,020$841.4K0.00%+68,020New
Boothbay Fund Management, LLC61,465$760.3K0.02%−112,647−64.7%Reduced
MetLife Investment Management55,941$692.0K0.00%+12,340+28.3%Added
China Universal Asset Management Co., Ltd.54,267$671.3K0.06%+30,276+126.2%Added
SG Americas Securities, LLC53,419$661.0K0.00%+16,856+46.1%Added
STRS Ohio52,900$654.4K0.00%−32,400−38.0%Reduced
Mirae Asset Global ETFs Holdings Ltd.52,392$648.1K0.00%+9,907+23.3%Added
Janus Henderson Group PLC51,700$639.3K0.00%00.0%Unchanged
Handelsbanken Fonder AB50,800$628.0K0.00%+50,800New
Wells Fargo & Company49,856$616.7K0.00%+22,873+84.8%Added
Glenmede Trust Co NA47,409$586.4K0.00%+8,334+21.3%Added
Intech Investment Management LLC47,146$583.2K0.01%+23,442+98.9%Added
Corebridge Financial, Inc.45,824$566.8K0.00%+4,423+10.7%Added