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Wave Life Sciences, Inc.

WVE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001631574

In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q2 2025

Institutional positions in Wave Life Sciences, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
177
−17 vs. Q1 2025
Shares held
138.9M
+7.62M (+5.8%) vs. Q1 2025
Total value
$903.1M
−$158.3M (−14.9%) vs. Q1 2025
New holders
23
84 more added
Sold out
40
39 more reduced

3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 177 institutions
Q1 2021: 102 institutionsQ2 2021: 87 institutionsQ3 2021: 88 institutionsQ4 2021: 90 institutionsQ1 2022: 82 institutionsQ2 2022: 60 institutionsQ3 2022: 61 institutionsQ4 2022: 75 institutionsQ1 2023: 73 institutionsQ2 2023: 81 institutionsQ3 2023: 85 institutionsQ4 2023: 115 institutionsQ1 2024: 132 institutionsQ2 2024: 144 institutionsQ3 2024: 162 institutionsQ4 2024: 184 institutionsQ1 2025: 197 institutionsQ2 2025: 177 institutionsQ3 2025: 189 institutionsQ4 2025: 219 institutionsQ1 2026: 232 institutionsQ2 2026: 239 institutions
Value heldQ2 2025: $903.1M
Q1 2021: $214.8MQ2 2021: $246.7MQ3 2021: $183.5MQ4 2021: $148.5MQ1 2022: $95.4MQ2 2022: $220.3MQ3 2022: $242.8MQ4 2022: $476.9MQ1 2023: $303.5MQ2 2023: $262.7MQ3 2023: $417.4MQ4 2023: $468.0MQ1 2024: $572.3MQ2 2024: $474.4MQ3 2024: $986.1MQ4 2024: $1.59BQ1 2025: $1.06BQ2 2025: $903.1MQ3 2025: $1.05BQ4 2025: $3.11BQ1 2026: $1.25BQ2 2026: $1.06B
Institutions holding WVE and their total value by quarter
QuarterHoldersValue
Q2 2026239$1.06B
Q1 2026232$1.25B
Q4 2025219$3.11B
Q3 2025189$1.05B
Q2 2025177$903.1M
Q1 2025197$1.06B
Q4 2024184$1.59B
Q3 2024162$986.1M
Q2 2024144$474.4M
Q1 2024132$572.3M
Q4 2023115$468.0M
Q3 202385$417.4M
Q2 202381$262.7M
Q1 202373$303.5M
Q4 202275$476.9M
Q3 202261$242.8M
Q2 202260$220.3M
Q1 202282$95.4M
Q4 202190$148.5M
Q3 202188$183.5M
Q2 202187$246.7M
Q1 2021102$214.8M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q1 2025.

Institutions holding WVE in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.18,202,009$118.3M1.99%00.0%Unchanged
Adage Capital Partners GP, L.L.C.15,016,500$97.6M0.16%+2,500,000+20.0%Added
BlackRock, Inc.10,383,716$67.5M0.00%+755,104+7.8%Added
Maverick Capital LtdSuperinvestorMaverick Capital8,261,683$53.7M0.82%00.0%Unchanged
Driehaus Capital Management LLC6,531,519$42.5M0.34%+172,920+2.7%Added
M28 Capital Management LP5,664,548$36.8M62.80%00.0%Unchanged
Price T Rowe Associates Inc5,190,403$33.7M0.00%+1,065,112+25.8%Added
Kynam Capital Management, LP4,560,053$29.6M3.19%−339,444−6.9%Reduced
683 Capital Management, LLC4,100,000$26.7M2.70%+175,000+4.5%Added
Bellevue Group AG4,094,458$26.6M0.59%00.0%Unchanged
Siren, L.L.C.3,696,322$24.0M1.24%00.0%Unchanged
Vanguard Group Inc3,477,077$22.6M0.00%+270,674+8.4%Added
Loomis Sayles & Co L P3,295,700$21.4M0.03%+859,160+35.3%Added
Emerald Advisers, LLC3,257,119$21.2M0.78%+123,561+3.9%Added
Geode Capital Management, LLC2,759,381$17.9M0.00%+166,982+6.4%Added
State Street Corp2,756,755$17.9M0.00%+338,792+14.0%Added
Primecap Management Co2,465,850$16.0M0.01%−41,670−1.7%Reduced
Artisan Partners Limited Partnership2,264,835$14.7M0.02%−105,318−4.4%Reduced
Affinity Asset Advisors, LLC2,000,308$13.0M1.92%+175,308+9.6%Added
Emerald Mutual Fund Advisers Trust1,937,489$12.6M0.77%+6,669+0.3%Added
Pfizer Inc1,875,000$12.2M2.12%00.0%Unchanged
JPMorgan Chase & Co1,569,015$10.2M0.00%+390,078+33.1%Added
Morgan Stanley1,544,038$10.0M0.00%+364,111+30.9%Added
MPM Oncology Impact Management LP1,505,262$9.78M1.70%−4,318−0.3%Reduced
Charles Schwab Investment Management Inc1,010,658$6.57M0.00%+47,533+4.9%Added
Northern Trust Corp1,008,782$6.56M0.00%+37,036+3.8%Added
Goldman Sachs Group Inc1,007,081$6.55M0.00%+449,437+80.6%Added
Polar Capital Holdings Plc1,003,500$6.52M0.03%00.0%Unchanged
StemPoint Capital LP900,338$5.85M1.88%+810,505+902.2%Added
RTW Investments, LP900,000$5.85M0.08%00.0%Unchanged
Millennium Management LLC692,415$4.50M0.00%+666,193+2,540.6%Added
Voloridge Investment Management, LLC683,193$4.44M0.02%−87,514−11.4%Reduced
Bank of America Corp645,560$4.20M0.00%+110,295+20.6%Added
Schroder Investment Management Group621,378$4.04M0.00%+142,109+29.7%Added
FMR LLC619,137$4.02M0.00%−1,525,690−71.1%Reduced
UBS Group AG607,272$3.95M0.00%+438,983+260.9%Added
Qube Research & Technologies Ltd591,384$3.84M0.01%+216,520+57.8%Added
Barclays PLC573,187$3.73M0.00%+311,973+119.4%Added
Walleye Capital LLC467,887$3.04M0.03%+77,047+19.7%Added
Woodline Partners LP452,060$2.94M0.02%00.0%Unchanged
Moody Aldrich Partners LLC421,852$2.74M0.53%−17,975−4.1%Reduced
Newtyn Management, LLC400,000$2.60M0.39%00.0%Unchanged
Universal- Beteiligungs- und Servicegesellschaft mbH358,429$2.33M0.00%−4,129−1.1%Reduced
Platinum Investment Management Ltd355,353$2.31M0.15%+43,361+13.9%Added
Baker Bros. Advisors LP344,063$2.24M0.02%00.0%Unchanged
Ensign Peak Advisors, Inc313,307$2.04M0.00%+313,307New
Principal Financial Group Inc302,276$1.96M0.00%−5,768−1.9%Reduced
Wellington Management Group LLP297,887$1.94M0.00%−1,782−0.6%Reduced
UBS Asset Management Americas Inc295,061$1.92M0.00%+111,659+60.9%Added
Bank of New York Mellon Corp289,282$1.88M0.00%+42,031+17.0%Added
Susquehanna Portfolio Strategies, LLC285,086$1.85M0.04%+270,758+1,889.7%Added
Dark Forest Capital Management LP280,765$1.82M0.07%+83,549+42.4%Added
Cinctive Capital Management LP277,764$1.81M0.10%+277,764New
D. E. Shaw & Co., Inc.271,474$1.76M0.00%+164,920+154.8%Added
Macquarie Group Ltd266,856$1.74M0.00%−5,470−2.0%Reduced
Nuveen, LLC249,469$1.62M0.00%+199,266+396.9%Added
F/M Investments LLC243,677$1.58M0.06%+3,259+1.4%Added
Two Sigma Investments, LP243,167$1.58M0.00%+1,453+0.6%Added
Susquehanna International Group, LLP224,426$1.46M0.00%+107,337+91.7%Added
Swiss National Bank205,200$1.33M0.00%+13,200+6.9%Added
TD Asset Management Inc179,608$1.17M0.00%+25,200+16.3%Added
Twinbeech Capital LP163,745$1.06M0.02%−232,303−58.7%Reduced
Manufacturers Life Insurance Company, The163,699$1.06M0.00%+7,913+5.1%Added
Rhumbline Advisers162,599$1.06M0.00%+29,899+22.5%Added
Ikarian Capital, LLC161,137$1.05M0.35%+161,137New
New York State Common Retirement Fund150,513$978.3K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.145,308$944.5K0.00%+87,959+153.4%Added
Privium Fund Management B.V.135,550$883.8K0.19%+22,000+19.4%Added
Boothbay Fund Management, LLC132,891$863.8K0.03%+86,145+184.3%Added
Wells Fargo & Company124,667$810.3K0.00%−98,295−44.1%Reduced
James J. Burns & Company, LLC121,913$792.4K0.13%00.0%Unchanged
Sofinnova Investments, Inc.117,903$766.4K0.05%+117,903New
Invesco Ltd.114,959$747.2K0.00%+36,079+45.7%Added
ADAR1 Capital Management, LLC114,814$746.3K0.12%+91,714+397.0%Added
Legal & General Group Plc102,050$663.3K0.00%−13,962−12.0%Reduced
Norges Bank100,000$650.0K0.00%00.0%Unchanged
Compass Rose Asset Management, LP100,000$650.0K0.24%+100,000New
California State Teachers Retirement System98,237$638.5K0.00%00.0%Unchanged
Citigroup Inc98,075$637.5K0.00%+6,914+7.6%Added
China Universal Asset Management Co., Ltd.93,370$606.9K0.06%+40,850+77.8%Added
Alliancebernstein L.P.92,830$603.4K0.00%−735−0.8%Reduced
Two Sigma Advisers, LP92,300$600.0K0.00%+62,700+211.8%Added
SEI Investments Co88,819$577.3K0.00%−3,792−4.1%Reduced
Deutsche Bank AG84,531$549.5K0.00%+13,621+19.2%Added
a16z Perennial Management, L.P.77,619$504.5K0.04%00.0%Unchanged
BNP Paribas Arbitrage, SA72,459$471.0K0.00%−161,194−69.0%Reduced
Superstring Capital Management LP70,242$456.6K0.57%+70,242New
MetLife Investment Management67,257$437.2K0.00%+11,854+21.4%Added
Intech Investment Management LLC66,194$430.3K0.00%−10,499−13.7%Reduced
Franklin Resources Inc61,982$402.9K0.00%+16,466+36.2%Added
Man Group plc59,279$385.3K0.00%+59,279New
Glenmede Investment Management, LP53,021$344.6K0.00%+53,021New
Verition Fund Management LLC52,728$342.7K0.00%−102,029−65.9%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)52,303$340.0K0.00%+10,329+24.6%Added
Janus Henderson Group PLC51,700$335.8K0.00%00.0%Unchanged
Handelsbanken Fonder AB50,800$330.0K0.00%+50,800New
Squarepoint Ops LLC46,154$300.0K0.00%+870+1.9%Added
Simplex Trading, LLC46,230$300.0K0.01%+34,716+301.5%Added
State of Wisconsin Investment Board45,458$295.5K0.00%−60,444−57.1%Reduced
Engineers Gate Manager LP44,413$288.7K0.00%−71,255−61.6%Reduced